1.A Case of Breast Carcinoma with Leser-Trelat Sign Responding to Tamoxifen.
Bum Joon KO ; Ga Hee JUNG ; Sang Hoon LEE ; Moon Kyun CHO ; Jong Suk LEE ; Sung Yul LEE
Korean Journal of Dermatology 2014;52(9):672-673
No abstract available.
Breast Neoplasms*
;
Tamoxifen*
2.Influence of tamoxifen and 17beta-estradiol on the growth of human cervical and ovarian cancer cells in vitro.
Lae Ok PARK ; Duck Yeong RO ; Jin Woo KIM ; Do Kang KIM ; Dae Heon KIM ; Seung Jo KIM
Korean Journal of Obstetrics and Gynecology 1991;34(1):63-69
No abstract available.
Humans*
;
Ovarian Neoplasms*
;
Tamoxifen*
3.A Case of Radiation Recall Dermatitis after Hormonal Therapy of Letrozol (Femara(R)).
Ji Young AHN ; Ji Young KIM ; Seong Jun SEO ; Chang Kwun HONG ; Kye Yong SONG
Korean Journal of Dermatology 2006;44(1):83-85
Radiation recall dermatitis gap (RRD) is the development of an inflammatory reaction throughout a previously irradiated area, precipitated by the administration of certain drugs. Usually chemotherapeutic agents have been associated with RRD, but other drugs reported include tamoxifen, interferon alfa-2b, simvastatin, and antituberculous drugs. We present a case of RRD after chemotherapy with letrozol (Femara(R)). Letrozol is a third generation aromatase inhibitor, which acts as an anti-estrogen agent. This is the first reported case of RRD triggered by letrozol.
Aromatase
;
Drug Therapy
;
Interferons
;
Radiodermatitis*
;
Simvastatin
;
Tamoxifen
4.Effect of calcitonin, NaF and tamoxifen on osteoporosis induced by ovariectomy in rat.
Hwan Mo LEE ; Byeong Mun PARK ; Hung Nam KIM
The Journal of the Korean Orthopaedic Association 1993;28(6):2273-2280
No abstract available.
Animals
;
Calcitonin*
;
Female
;
Osteoporosis*
;
Ovariectomy*
;
Rats*
;
Tamoxifen*
5.Invasive ductal carcinoma in a 51-year-old male: Case report
Stephen Matthew B Santos ; Eillen A Borje
Southern Philippines Medical Center Journal of Health Care Services 2019;5(2):1-8
Male breast cancer (MBC), which constitutes only 1% of all breast cancer cases worldwide, is associated with mutations in the BRCA1 and BRCA2 genes, Klinefelter’s syndrome and a positive family history of breast or ovarian malignancy. Patients with MBC typically present with a palpable subareolar mass, with or without nipple involvement. MBC can be identified by mammography and/or ultrasonography. The definitive diagnosis is made through core needle biopsy and cytology. Breast cancer in men are typically low-grade, and usually estrogen- and progesterone-receptor positive. The surgical treatment of choice is usually a modified radical mastectomy. Hormone therapy, can be used as first-line treatment for hormone-receptor positive MBC, and as adjuvant or palliative therapy for advanced cases. The use of adjuvant cytotoxic chemotherapy has been shown to reduce cancer recurrence and improve overall survival. We present the case of a 51-year-old male who came in due to an enlarging right breast mass that had been removed twice in the past eight years. We were able to establish that the patient had MBC, for which he subsequently underwent a modified radical mastectomy
Klinefelter Syndrome
;
Mastectomy, Modified Radical
;
Tamoxifen x
6.In vitro respones of gynecological cancer cell lines to the GnRH agonist, medroxyprogesterone acetate and tamoxifen.
Jong Woo SOHN ; Jai Kyung PRK ; Seon Kyung LEE ; Seung Bo KIM ; Bo Hoon OH
Korean Journal of Obstetrics and Gynecology 1993;36(9):3436-3443
No abstract available.
Cell Line*
;
Gonadotropin-Releasing Hormone*
;
Medroxyprogesterone Acetate*
;
Medroxyprogesterone*
;
Tamoxifen*
7.Tamoxifen Only versus L-Carnitine and Tamoxifen in the Oral Therapy of Peyronie's Disease.
Korean Journal of Andrology 2006;24(1):8-12
PURPOSE: To evaluate the effects of oral Tamoxifen only versus L-Carnitine plus Tamoxifen in patients with Peyronie's disease. MATERIALS AND METHODS: All 45 patients with Peyronie's disease, diagnosed using accepted definitions, were randomized into two groups and treated for 3 months with Tamoxifen only(40 mg/day)(n=17) or a combination ofL-Carnitine(2 g/day) and Tamoxifen(40 mg/day)(n=28). A medical history was obtained, and a physical examination was performed. Plaque size, pain, erectile function(IIEF score), and penile curvature were assessed. Both before and after therapy, the differences between the 2 groups were compared using independent-sample t-test with p<0.05 considered significant. RESULTS: The mean age of the 45 patients was 52.1 years, and no severe adverse events occurred in either group. In the Tamoxifen only group, the mean decrease of plaque-length was 0.46+/-0.88 mm, and mean reduction in the pain rating scale was 0.44+/-0.53. In the L-Carnitine and Tamoxifen group, mean decrease of plaque-length was 1.57+/-0.92 mm, and mean reduction in the pain rating scale was 1.27+/-0.96. Based on IIEF scores, the improvement of erectile function was 0.88+/-0.64 in the Tamoxifen only group and 1.56+/-0.75 in the L-Carnitine and Tamoxifen group. The degree of penile curvature was also measured, and the reduction of curvature angle was 9.17+/-4.92 degrees in the Tamoxifen only group and 9.55+/-6.50 degrees in the L-Carnitine and Tamoxifen group. CONCLUSIONS: This study showed significantly greater improvements in plaque size, pain, erectile function, and curvature in patients with Peyronie's disease who were treated with L-Carnitine and Tamoxifen compared with those treated with Tamoxifen only.
Carnitine*
;
Humans
;
Male
;
Penile Induration*
;
Physical Examination
;
Tamoxifen*
8.Effects of verapamil, tamoxifen and cyclosporin A for the modulation of multidrug resistance in human lung cancer lines.
Joo Hang KIM ; Byung Soo KIM ; Jung Joo CHOI ; Kyung Mi KIM ; Nae Choon YOO ; Jin Hyuk CHOI ; Ho Young LIM ; Jae Kyung ROH ; Kyung Sik LEE ; Byung Soo KIM
Journal of the Korean Cancer Association 1993;25(2):225-235
No abstract available.
Cyclosporine*
;
Drug Resistance, Multiple*
;
Humans*
;
Lung Neoplasms*
;
Lung*
;
Tamoxifen*
;
Verapamil*
9.Effect of Potassium Aminobezoate in Oral Therapy for Peyronie's Disease: Preliminary Study.
Byeong Kuk HAM ; Jong Jin PARK ; Tae Il NOH ; Sang Woo KIM ; Tae Yong PARK ; Sun Tae AHN ; Mimi OH ; Du Geon MOON
Korean Journal of Andrology 2011;29(3):213-217
PURPOSE: To evaluate the effect and improvement of potassium aminobenzoate (500 mg Peyron capsule) in oral therapy for Peyronie's disease. MATERIALS AND METHODS: From February 2011 to September 2011, 31 patients with Peyronie's disease received potassium aminobezoate (500 mg Peyron capsules) and were divided into two groups. Group 1 (N=10) received potassium aminobezoate (500 mg Peyron capsule) 3 g four times daily without previous treatment of Peyronie's disease, while group 2 (N=21) received the same drug with previous treatment of Peyronie's disease (10 mg Tamoxifen +300 mg L-carnitine two times daily). Outcomes were assessed by subjective symptom change, pain relief, resolutions of the plaque, and curvature. RESULTS: After 3 months, there were no significant improvements in clinical outcomes of either group and among all the patients, 23 stopped taking potassium aminobezoate (23/31, 74%). The reasons for ceasing the therapy were gastrointestinal trouble (8/23, 35%), too many doses to take (7/23, 30%), ineffectiveness (6/23, 26%), and high price (2/23, 9%). CONCLUSIONS: Athough the etiology of Peyronie's disease has not been elucidated, potassium aminobenzoate in therapy of Peyronie's disease has been used. The use of this medication has the limitations of gastrointestinal trouble, ineffectiveness, too many doses, and high price. Further evaluations of the effect and appropriate dosing of potassium aminobenzoate are needed.
4-Aminobenzoic Acid
;
Carnitine
;
Humans
;
Male
;
Penile Induration
;
Potassium
;
Tamoxifen
10.Idiopathic Retroperitoneal Fibrosis Treated with Medical Therapy.
Myung Hoon KWON ; Joon Hwa NOH ; Lee Chul YANG ; Joon BAE ; Young Bong JEONG ; Sang Ik KIM
Korean Journal of Urology 2002;43(3):246-249
Retroperitoneal fibrosis, although benign, has a malignant course due to an encasement and obstruction of the retroperitoneal structures, particularly the urinary system. The most common treatment is often a surgical exploration followed by urologic intervention. However, steroid or azathioprine therapy has been advocated, with varying results and major side-effects. Recently, the successful medical therapy in patients with an early stage and low malignant potential has been reported. Here we report a male patient who underwent successful treatment of an idiopathic retroperitoneal fibrosis with tamoxifen and prednisolone.
Azathioprine
;
Humans
;
Male
;
Prednisolone
;
Retroperitoneal Fibrosis*
;
Tamoxifen
;
Ureter