The patient was a 52-year-old man with a history of antiphospholipid syndrome (APS), renal dysfunction and myasthenia gravis (MG). On May 2, 1998, he had sudden chest pain while sleeping. Enhanced computed tomography revealed acute aortic dissection (DeBakey type I). We performed emergency graft replacement of the ascending aorta and the aortic arch under extracorporeal circulation. Because of perioperative anuria, we used peritoneal dialysis (PD) just after the operation. Two days after the operation, we performed re-intubation nine hours after the extubation of the tracheal tube, and performed re-extubation three days later. For a while, his postoperative course was uneventful, but because of gradual worsening of APS, we administered more prednisolone, but 74 days after the operation, he died of multiple organ failure caused by an opportunistic infection, sepsis, and disseminated intravascular coagulation. This was very rare case of acute aortic dissection with MG and APS. After administration of more glucocorticoids, it is important to be wary of opportunistic infections.

In this study, we investigated the relationship of an osteoarthritis of the knee (OA) and a knee pain of single-leg on the bilateral difference of ground reaction force in stepping. The subjects were 29 middle-aged women (mean age 63.7±6.7 years). We categorized them into groups based on the following conditions: osteoarthritis of the knee (OA groups; n = 9), knee pain (KP groups; n = 7), and no pain (NP groups; n = 13). We measured the ground reaction force in a vertical direction when stepping on a platform. The evaluation variables were as follows: peak of ground reaction force at the early stance phase (F1), middle phase (F2), and late phase (F3). We calculated the bilateral difference of ground reaction force of the left and right leg and the affected side and the unaffected side ratio. The result of two way ANOVA, there was a significant difference between the leg in F1 and F3 and the group at F2. The result of comparison between the OA groups and the KP groups, there was no significant difference in the unaffected side and the affected side ratio, those in the OA groups tended to have a load on the unaffected side, while those in the KP groups had a load on the affected side. Therefore, it was suggested that there was the relationship of the OA and a knee pain of single-leg on the bilateral difference of ground reaction force in stepping.