1.Isolation and structural determination of urs 12-en-3 beta -acetyloxy extracted from Radix-Streptocauli
Pharmaceutical Journal 1999;282(10):13-15
From a polar fraction, obtained from alcoholic root extract of Streptocaulon juventas by fractionated precipitation and liquid-liquid extractions, 5 pure compounds (St3 - St7) were isolated by chromatographical methods besides two formerly reported compounds - lupeol acetate and lupeol. Of those, the structure of St3. was deduced to be urs-12-en-3-acetyloxy by their spectroscopic data compared to those of published data of related compounds. To the best of our knowledge, this is the first time this compounds are known as constituents of the plant and also of the genus Streptocaulon
Plants, Medicinal
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Medicine, Traditional
2.Suicidal ideation and adverse experiences among adolescents with their separated/divorced parents in Hue city
Thi Tra My TRAN ; Binh Thang TRAN ; Minh Tam NGUYEN ; Nu Hong Duc VO ; Van Thong NGUYEN ; Ngo Bao Khuyen NGUYEN ; Thi Thu Ha PHAM ; Uyen Phuong HO ; Hoang Linh VO ; Thi Thu Tham LUONG ; Tuan Anh HOANG ; Cao Khoa DANG ; Thanh Gia NGUYEN ; Minh Tu NGUYEN
Hue Journal of Medicine and Pharmacy 2023;13(6):25-
Background: Suicide continues to be a leading cause of death worldwide. Recently, more than 45,000 children in the age group of 10 to 19 years died by suicide, making it the second leading cause of death in the age group of 15 to 19, surpassed only by traffic accidents, tuberculosis, and fighting. Objective: To determine the prevalence of suicidal ideation among adolescents whose parents are separated/divorced; and to explore the factors associated with suicidal ideation and describe adverse experiences among adolescents. Methods: A cross-sectional descriptive study was conducted in 309 adolescents with separated/separated parents in Hue City. Data was collected through direct interviews using a structured questionnaire. Suicidal ideation was defined as the presence of thoughts or plans related to suicide within the last 12 months. Multivariate logistic regression was applied to identify factors associated with suicidal ideation in adolescents with separated/ separated parents. Results: The study found that 15.5% (95% CI:11.7 - 20.1) of adolescents with separated /separated parents reported experiencing suicidal thoughts, in which men accounted 8.4% (95% CI:5.6 – 11.2) and women accounted 7.1% (95% CI:4.5 - 10.6). Several factors were identified as increasing the risk of suicidal ideation, including alcohol use (OR = 3.24; 95% CI:1.42 - 7.42), hyperactivity/inattention (OR = 4.96; 95% CI:1.58 - 15.605), and a poor quality of family relationships (OR = 4.82; 95% CI:1.26 - 18.50). On the contrary, certain factors were found to reduce the risk, including being in the 14-15 age group of 14-15 (OR = 0.26; 95% CI:0.10 - 0.69) and participating in physical activity (OR = 0.44; 95% CI:0.21 – 0.94). Conclusions: The research highlights a significant percentage of adolescents with separated / divided parents who experience suicidal ideation. Therefore, it is imperative for families, schools, and society to develop comprehensive strategies to monitor and address various risky behaviours among students simultaneously.