The formula of the skin cream containing the extracts of Centella asiatica (L.) Urb. and Curcuma longa L. - the two medicinal plants available in Vietnam – was established by means of experimental design and computer – aided optimization. At first, the formulae were designed by varying the amounts of their ingredients such as Polawax, cetostearyl alcohol, Tween 80 and Span. Then, the Oil-in-Water emulsion – type creams were manufactured by using the PUC VIKOSATOR emulsor. Next, the resulted products were evaluated for their physics – chemical parameters including the melting point, the extrudability and the number of the Oil particles. After that, the multiple – objective optimization was performed by the CAD/Chem artificial intelligence software, which is the unification of neural networks, fuzzy logic and genetic algorithms. At the end, the optimized formula was strictly evaluated by both hypothetical tests and experimental trials. In drug quality control, the investigation of skin cream was proven to meet its ointment requirements.
Cookery ; Chemistry ; Pharmaceutical ; Plants, Medicinal

Two samples Amomum from NinhThuan were investigated. They were identified as Amomum thyrsoideum Gagnep. and Amomum longiligulare T.L. Wu. The leaf-oils and fruit-oils from two varitae were analysed by GC/MS. 14 compounds were detected in the leaf-oils and 19 in the fruit-oils. The main components in the leaf-oils, from A. thyrsoideum were cis-Ocimene (39.03%) and -Pinene (41.55%), from A. longiligulare were -Pinene (22.50%) and -Pinene (61.77%). The main components of the fruit-oils were camphor (34.29-35.77% and 44.46%) and bornyl acetate (41.22-43.25%, and 26.62%). The fruits from the two varieties are rich on essential oil. The amount of oil were 3.0-3.75%
Amomum ; Oils ; Plants, Medicinal ; Medicine, Traditional

Investigatetion of the fruits and leaves oil of Litsea cubeba (Lour.) Pers. wild growing in the moutain areas in Ba Vi district, Ha Tay province. The major components of the fruits oil of Litsea cubeba (Lour.) Pers. is citral, which includes of neral (citral b) and geranial (citral a) with content over 65% equivalent in some Northern provinces. Fruits and leaves oil analysis were carried out by a combination of capilarry GC and MS. The main components of the leaves oil are linalol (over 85%), 1.8-cineol (-50%), sabinen (10-15%) and -terpineol or -terpinyl acetate (10-20%). This plant in Ba Vi has many biochemical diversification, that is also a character of Lauraceae as Long nao, Vu huong.
Plants ; Biochemistry ; Medicine, Traditional ; Oils

Materials and methods: Fruits and leaves of Litsea cubeba (Lour.) Pers. were collected in August 2001. The essential oil analysis was carried out by combination of capillary gas chromatography and mas spectrometry. Results: 16 constituents were identified in the fruit oil, and 27 in the leaf oil. The major components of the fruit oil were geranial (46.83%) and neral (38.77%). The monoterpenic hydrocarbon compounds occurred in a very low amount, except l-limonene (2.14%). The other oxygenated compounds as well as the sesquiterpenic compounds were only about 1%. The major constituents of the leaf oil were cis-ocimene (42.84%) and cineole (10.54%). In addition, there were: linalool (2.07%), terpinene-4-ol (3.65%) and alpha-terpineol (3.65%). The monoterpenic hydrocarbon compounds were found at the level of 74.56%.
Chemistry ; Biochemistry ; Plants

Analysis on chemical contents of essential oil of Hybtis suaveolens (L) Poit collected in Ninh Thuan, Vung Tau and Phu Quocs showed that: 41 ingredients in essential oil of wild Hybtis suaveolens (L) Poit were identified by chromatography combining with mass spectrum. Hybtis suaveolens (L) Poit collected in others local but its compositions were rather similar. Major compositions was beta-caryophylen (30.35-44.27%) and 1,8-cineol (7.34-28.20%). In addition, some familiar monoterpens such as alpha - pinen, beta-pinen, sabinen, myrcen were in all three essential oils. Essential oil of Hyptis suaveolens (L.) Poit. had strong scent. With rather high content of sesquiterpen, essential oil of Hyptis suaveolens (L.) Poit. can be used as flavouring indicator in flavouring technology
Oils, Volatile ; yptis ; Epidemiology

Essential oils of leaves and trunk barks of Cinnamomum cassia J.S. Persl. of two different origins (Quang Nam and Thanh Hoa) have been grown in Phuoc Son district, Quang Nam province were selected and analyzed by GC/MS. The barks of Quang Nam origin gave higher oil percentage and cinnamaldehyde content (6.80% and 88.74%, respectively), while those of Thanh Hoa origins were only 0.65% and 67.39%, respectively
Cinnamomum aromaticum ; Oils, Volatile ; Plant Leaves

Clinical trial was carried out on 30 patients (28 females, 2 males at the age of 18 and 60 years old) with low blood pressure (systolic blood pressure <90mmHg and/or diastolic blood pressure <60mmHg) with other clinical symptoms such as headache, dizzy, fatigue, and insomnia were treated by 'Sinh mach Bao nguyen' tea- a herbal formula of traditional medicine. After 30 days of treatment, 93.33% of patients have higher blood pressure. Some clinical symptoms reduced significantly. There was no side-effect
Hypertension ; Blood Pressure ; Therapeutics ; Medicine, Traditional ; Tea

The study had been conducted in 85 patients aged from 22-49, who were diagnosed as cervical erosion to find out the effect of cryosurgery method. Results: this method was effective in treating cervical erosion; 80% of the patients recovered after the 1st time treatment and 20% in the 2 nd times. The percentage of the recovery related to diameter injuries. This method did not cause any serious complications but some light complications such as disordered menstruation (17.6%), menorrhagia (11.8%), backache or lower backache (5.9%), appendage inflammation (4.7%). After the treatment, 8.2% of these cases are able to get pregnant and give birth as common
Uterine Cervical Erosion, Cryosurgery, Therapeutics

With the method of water vapor distillation using the "modified apparatus for quantifying essential oil" of Ha Noi college of Pharmacy the essential oil was analysed by GC/MS. Results found essential oil in all organs of the plant such as root, stem, small branch and leaf, but the most was in leaf. The essential oil is a yellow liquid, heavier considerably than water. In the above- ground organs, there is almost 98,45%-99,03% of methyl salicylat. In the root, this content is lower, an addition with other components such as delta- tetradecalaction caryophylen oxid, nootkalon
Chemistry ; Oils, volatile ; Gaultheria

16 adult rabbits induced the experimental superficial thermal burn was randomly divided into 2 groups: group I treated by hyperbasic oxygen combining with saline and group II (control) only treated by saline. The bacterial tests implemented after 3,7 and 14 days of the treatment have shown that the hyperbasic oxygen inhibited the common bacteria in the infected burns. In the 14 days, the rate of burns infected S.aureus and P.acruginosa and number of bacterials/1cm2 of burn surface in the group I was less this in group II (control).
burns ; Hyperbaric Oxygenation