1.To study the therapeutic effects of 'Sinh mach Bao nguyen" tea on low blood pressure
Journal of Medical and Pharmaceutical Information 2003;0(3):27-29
Clinical trial was carried out on 30 patients (28 females, 2 males at the age of 18 and 60 years old) with low blood pressure (systolic blood pressure <90mmHg and/or diastolic blood pressure <60mmHg) with other clinical symptoms such as headache, dizzy, fatigue, and insomnia were treated by 'Sinh mach Bao nguyen' tea- a herbal formula of traditional medicine. After 30 days of treatment, 93.33% of patients have higher blood pressure. Some clinical symptoms reduced significantly. There was no side-effect
Hypertension
;
Blood Pressure
;
Therapeutics
;
Medicine, Traditional
;
Tea
2.Assessing the results of treatment of cervical erosion by cryosurgery
Journal of Medical and Pharmaceutical Information 2004;0(1):33-36
The study had been conducted in 85 patients aged from 22-49, who were diagnosed as cervical erosion to find out the effect of cryosurgery method. Results: this method was effective in treating cervical erosion; 80% of the patients recovered after the 1st time treatment and 20% in the 2 nd times. The percentage of the recovery related to diameter injuries. This method did not cause any serious complications but some light complications such as disordered menstruation (17.6%), menorrhagia (11.8%), backache or lower backache (5.9%), appendage inflammation (4.7%). After the treatment, 8.2% of these cases are able to get pregnant and give birth as common
Uterine Cervical Erosion, Cryosurgery, Therapeutics
3.Local bacterial flora changes in the experimental supraficial thermal burn under hyperbaric oxygen
Journal of Practical Medicine 2002;242(6):81-82
16 adult rabbits induced the experimental superficial thermal burn was randomly divided into 2 groups: group I treated by hyperbasic oxygen combining with saline and group II (control) only treated by saline. The bacterial tests implemented after 3,7 and 14 days of the treatment have shown that the hyperbasic oxygen inhibited the common bacteria in the infected burns. In the 14 days, the rate of burns infected S.aureus and P.acruginosa and number of bacterials/1cm2 of burn surface in the group I was less this in group II (control).
burns
;
Hyperbaric Oxygenation
4.Efficacy of hyper pressure oxygen therapy in the local treatment of deep thermal burn
Journal of Practical Medicine 2002;408(2):36-39
The study of hyperbaric oxygen therapy (HBOT) on the full thickness thermal burn wound was done in 24 rabbits. After infliction of the burn wound, the animals were randomized into 2 groups: a HBOT group (n=12) and non-HBOT group (n=12). Studying a change of the burn wound, we found that (1) HBOT had statistically significant effect on anti inflammation (p<0.01). (2) HBOT had statistically significant effect on decrease the time of necrosis separation (p<0.01). HBOT had statistically significant effect on decrease the time of burn wound healing.
burns
;
therapeutics
5.Formulation and optimization of the recipe of Centella asiatica and Curcuma longa cream
Pharmaceutical Journal 2001;298(2):15-18
The formula of the skin cream containing the extracts of Centella asiatica (L.) Urb. and Curcuma longa L. - the two medicinal plants available in Vietnam – was established by means of experimental design and computer – aided optimization. At first, the formulae were designed by varying the amounts of their ingredients such as Polawax, cetostearyl alcohol, Tween 80 and Span. Then, the Oil-in-Water emulsion – type creams were manufactured by using the PUC VIKOSATOR emulsor. Next, the resulted products were evaluated for their physics – chemical parameters including the melting point, the extrudability and the number of the Oil particles. After that, the multiple – objective optimization was performed by the CAD/Chem artificial intelligence software, which is the unification of neural networks, fuzzy logic and genetic algorithms. At the end, the optimized formula was strictly evaluated by both hypothetical tests and experimental trials. In drug quality control, the investigation of skin cream was proven to meet its ointment requirements.
Cookery
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Chemistry
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Pharmaceutical
;
Plants, Medicinal
6.Study fluctuation and confirmation of Japanese encephalitis vector in Ha Nam province, 2006-2007 \r\n', u'\r\n', u'
Thoang Dinh Dang ; Tam Ngoc Nguyen ; Trang Minh Bui ; Yen Thi Nguyen ; Nga Thi Phan
Journal of Preventive Medicine 2008;0(3):45-53
Background: Japanese Encephalitis (JE) virus is a leading cause of encephalitis in children with high mortality and complication. JE is a dangerous infectious disease via Culex mosquitoes. Objective: To identify the density of some mosquitoes and vectors that transmit JE virus in Ha Nam province. Subject and Method:There were 30.333 mosquitoes including 05 genera and 15 species which were collected at night from April 2006 to March 2007 in the following communes: Tanson (midland area) Hungcong (plain area) and Liemchinh (suburban area). Results: A total of 06 Culex species, the highest rate is Culex tritaeniohychus (41.20%); Culex annulus (15.56%); other Culex species occupied around 0.15% -2.49%. In these communes, the density of Culex tritaeniohychus was higher than Culex annulus. They were found to be active all year round, but the highest density of Culex tritaeniohychus and Culex annulus is 5.86 and 2.15, respectively in April and fall to 4.35% and 1.71% in July. The collected mosquitoes during April, May, June and July includes 133 and 28 Culex tritaeniohychus and Culex annulus pools, respectively; all were to be processed for the isolation of Japanese Encephalitis (JE) virus. There were 12 Culex tritaeniohychus and 2 Culex annulus pools which were collected in Tanson commune yielding positive. Conclusion: The results were confirmed that Culex tritaenioohychus and Culex annulus are the major vectors that transmit JE virus in Ha Nam, 2006 - 2007. All 14 JE virus strains were isolated from collected mosquito pools during April, May and June; whereas JE virus strain was not yet isolated from collected mosquito pool in July. Thus, in order to control JE disease, it is necessary to control JE vectors in April, May and June.
Vector
;
Culex tritaenioohychus
;
Japanese encephalitis
;
Ha Nam
7.Does conventional freezing affect sperm DNA fragmentation?
Minh Tam LE ; Thai Thanh Thi NGUYEN ; Tung Thanh NGUYEN ; Trung Van NGUYEN ; Tam An Thi NGUYEN ; Quoc Huy Vu NGUYEN ; Thanh Ngoc CAO
Clinical and Experimental Reproductive Medicine 2019;46(2):67-75
OBJECTIVE: Sperm cryopreservation has been widely used in assisted reproductive technology, as it offers great potential for the treatment of some types of male infertility. However, cryopreservation may result in changes in membrane lipid composition and acrosome status, as well as reductions in sperm motility and viability. This study aimed to evaluate sperm DNA fragmentation damage caused by conventional freezing using the sperm chromatin dispersion test. METHODS: In total, 120 fresh human semen samples were frozen by conventional methods, using SpermFreeze Solution as a cryoprotectant. Routine semen analysis and a Halosperm test (using the Halosperm kit) were performed on each sample before freezing and after thawing. Semen parameters and sperm DNA fragmentation were compared between these groups. RESULTS: There was a significant decrease in sperm progressive motility, viability, and normal morphology after conventional freezing (32.78%, 79.58%, and 3.87% vs. 16%, 55.99%, and 2.55%, respectively). The sperm head, midpiece, and tail defect rate increased slightly after freezing. Furthermore, the DNA fragmentation index (DFI) was significantly higher after thawing than before freezing (19.21% prior to freezing vs. 22.23% after thawing). Significant increases in the DFI after cryopreservation were observed in samples with both normal and abnormal motility and morphology, as well as in those with normal viability. CONCLUSION: Conventional freezing seems to damage some sperm parameters, in particular causing a reduction in sperm DNA integrity.
Acrosome
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Chromatin
;
Cryopreservation
;
DNA Fragmentation
;
DNA
;
Freezing
;
Humans
;
Infertility, Male
;
Male
;
Membranes
;
Reproductive Techniques, Assisted
;
Semen
;
Semen Analysis
;
Sperm Head
;
Sperm Motility
;
Spermatozoa
;
Tail
8.Thinning and drilling laser-assisted hatching in thawed embryo transfer: A randomized controlled trial.
Minh Tam LE ; Thi Tam An NGUYEN ; Thi Thai Thanh NGUYEN ; Van Trung NGUYEN ; Dinh Duong LE ; Vu Quoc Huy NGUYEN ; Ngoc Thanh CAO ; Alar AINTS ; Andres SALUMETS
Clinical and Experimental Reproductive Medicine 2018;45(3):129-134
OBJECTIVE: In frozen and thawed embryos, the zona pellucida (ZP) can be damaged due to hardening. Laser-assisted hatching (LAH) of embryos can increase the pregnancy rate. This study compared thinning and drilling of the ZP before frozen embryo transfer (FET). METHODS: Patients were randomly allocated into two groups for LAH using thinning or drilling on day 2 after thawing. Twenty-five percent of the ZP circumference and 50% of the ZP thickness was removed in the thinning group, and a hole 40 µm in diameter was made in the drilling group. RESULTS: A total of 171 in vitro fertilization/intracytoplasmic sperm injection FET cycles, including 85 cycles with drilling LAH and 86 cycles with thinning LAH, were carried out. The thinning group had a similar β-human chorionic gonadotropin-positive rate (38.4% vs. 29.4%), implantation rate (16.5% vs. 14.4%), clinical pregnancy rate (36.0% vs. 25.9%), miscarriage rate (5.8% vs. 2.4%), ongoing pregnancy rate (30.2% vs. 23.5%), and multiple pregnancy rate (7.0% vs. 10.6%) to the drilling LAH group. There were no significant differences in pregnancy outcomes between subgroups defined based on age (older or younger than 35 years) or ZP thickness (greater or less than 17 µm) according to the LAH method. CONCLUSION: The present study demonstrated that partial ZP thinning or drilling resulted in similar outcomes in implantation and pregnancy rates using thawed embryos, irrespective of women's age or ZP thickness.
Abortion, Spontaneous
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Chorion
;
Embryo Transfer*
;
Embryonic Structures*
;
Female
;
Humans
;
In Vitro Techniques
;
Methods
;
Pregnancy
;
Pregnancy Outcome
;
Pregnancy Rate
;
Pregnancy, Multiple
;
Reproductive Techniques, Assisted
;
Spermatozoa
;
Zona Pellucida
9.Epidemiological characteristics of HIV/AIDS patients and community care in Thua Thien Hue
Ngoc Thi Tran ; Son Dinh Nguyen ; Minh Quang Duong ; Hoa Thai Nguyen ; Tam Le Nguyen ; Son Van Ly ; Son Huu Le ; Dung My Tran ; Hao Van Huynh
Journal of Preventive Medicine 2007;17(4):39-44
Background: HIV/AIDS pandemic really become danger to mankind on the earth. Objectives: Description epidemiological characteristics of HIV/AIDS patients. Studying clinical expression, learning aboutdemands of infected patients and community care for infected patients. Subjects and method: 71 HIV/AIDS people in Thua Thien Hue were studied in 2006. Using descriptive method to give epidemiological characteristics and behaviour of HIV/AIDS people. People were determined HIV/AIDS infection based on the criteria of Ministry of Health. The information were collected by target study. Results: HIV/AIDS people mainly from the age of 20 to 39 (83,10%), males were 52,10% and in various levels of education and all kinds of occupation. The rate of sexually transmitted infection was 84,5% and infection transmission was 15,5%. The rate of sexually transmitted infection within the last 12 months was 57,7%. 63,4% of infected people used condom while having sex with their spouses or partners. 1,4% of infected people using drug infection within the last month. 38% of the infected people had manifestations of AIDS, 77,8% of HIV/AIDS were treated with antiviral drugs. Families and communities had positive attitudes and behaviors to the HIV/AIDS people. Infected people being remoted from the society was 12,7%, 88,7% of them receiving supports from their communities such as disease treatment, spirit and material supports and job opportunities. Conclusion: Strengthen communication activities to change behavior of HIV/AIDS people and in communitiy to reduce alienation, discrimination for infected people. Execute socialization in care and support for HIV/AIDS people.
HIV/ immunology
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isolation &
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purification
;
pathogenicity
;
Community Health Services/ organization &
;
administration
;
Epidemiologic Methods
;
10.Mental health and its determinants among adolescents living in families with separated or divorced parents in an urban area of Vietnam
Binh Thang TRAN ; Minh Tu NGUYEN ; Minh Tam NGUYEN ; Thanh Gia NGUYEN ; Vo Nu Hong DUC ; Thi Tra My TRAN
Osong Public Health and Research Perspectives 2023;14(4):300-311
Objectives:
We assessed the prevalence of stress, anxiety, and depression among adolescents living in families with separated or divorced parents in Hue City, Vietnam and identified factors associated with these conditions.
Methods:
This cross-sectional study enrolled 309 adolescents, aged 12 to 17 years, living in families with separated or divorced parents in Hue City, Vietnam. The depression anxiety stress scale-21 (DASS-21) was used to measure stress, anxiety, and depression. Predictors of overall and individual mental health problems were identified using ordered and binary logistic regression, respectively.
Results:
The DASS-21 scale revealed a 49.2% prevalence of stress, while anxiety and depression had s prevalence rates of 61.5%. Among participants, 42.4% experienced all 3 mental health issues. Several factors were identified as significant predictors of mental health problems, including poor to average economic status (adjusted odds ratio [aOR], 2.00; 95% confidence interval [CI], 1.21–3.31; p=0.007); being in high school (aOR, 5.02; 95% CI, 2.93–8.60; p<0.001); maternal occupation of teacher, healthcare professional, or official (aOR, 2.39; 95% CI, 1.13–5.03; p=0.022); longer duration of family separation or divorce (aOR, 1.24; 95% CI, 1.05–1.45; p=0.009); living with one’s mother (aOR, 1.69; 95% CI, 1.03–2.76; p=0.04); alcohol consumption (aOR, 1.70; 95% CI, 0.99–2.92; p=0.050); and being bullied (aOR, 5.33; 95% CI, 1.10–25.69; p=0.037). Most of these factors were associated with stress, anxiety, and depression. Additionally, smoking was associated with stress.
Conclusion
Adolescents with separated or divorced parents were at increased risk of stress, anxiety, and depression. The findings of this study provide important implications for prevention programs.