The purpose of this study was to clarify the factor structure of the diversifying interpersonal work of pharmacists and its influential factors. A questionnaire-based survey was conducted for pharmacists registered with an internet research company. We collected data on respondents’ basic characteristics (gender and age), years of experience as a pharmacist, whether the respondents were certified as pharmacists, home-care experience, participation in study sessions and workshops, and experiences related to medication support. Factor analysis revealed three main factors from 26 items regarding pharmacists’ interpersonal work: Factor 1, “basic abilities of patient medication record management and medication counseling,” Factor 2, “clinical knowledge and assessment ability,” and Factor 3, “cooperation and support system.” Multiple regression analysis revealed a significant association between age and Factor 1 (β=−0.131, P<0.001). Home-care experience was associated with Factor 2 (β=0.076, P=0.013) and Factor 3 (β=0.115, P<0.001). Participation in study sessions and workshops were significantly associated with all the factors (Factor 1: β=0.103, P=0.001, Factor 2: β=0.247, P<0.001, Factor 3: β=0.238, P<0.001). This study clarified the factor structure of interpersonal work performed by community pharmacists. It is suggested that providing educational programs based on pharmacists’ ages and strengthening regional cooperation such as home medical care are necessary to standardize the quality of pharmacists’ interpersonal work.