1.Results of Mass Gastric Examination Conducted by the Nagano Prefectural Welfare Federation of Agricultural Cooperatives
Zenji Shimizu ; Kenji Usui ; Shigenobu Terashima ; Yoshio Takahashi ; Yoshimaru Sugiyama ; Tsutomu Fujita ; Kunihiro Oguchi ; Hajime Fushimi ; Etsuji Sano ; Takao Suzuki ; Takeshi Okada
Journal of the Japanese Association of Rural Medicine 1983;31(5):744-752
In order to carry out mass examination for detection of stomach ailments effectively and improve screening accuracy, the Nagano Prefectural Welfare Federation of Agricultural Cooperatives, with its mass gastric examination committee as a driving force, has made every endeavor in close collaboration with Federation-affiliated hospitals.
The ratio of those receiving detailed examination to the total number of those who have undergone mass screenings, and the detection ratio of gastric cancer cases, especially those in early stages, have increased steadily over the past years.
This is due in the main to untiring effort exerted by public health nurses and other persons concerned with health problems.
However, the results of X-ray examination made on the basis of the diagnostic standards prepared by the Federation show that there is much need of improving examiners' ability to read mass miniature radiographs correctly.
2.Necessity of pharyngeal anesthesia during transoral gastrointestinal endoscopy: a randomized clinical trial
Tomoyuki HAYASHI ; Yoshiro ASAHINA ; Yasuhito TAKEDA ; Masaki MIYAZAWA ; Hajime TAKATORI ; Hidenori KIDO ; Jun SEISHIMA ; Noriho IIDA ; Kazuya KITAMURA ; Takeshi TERASHIMA ; Sakae MIYAGI ; Tadashi TOYAMA ; Eishiro MIZUKOSHI ; Taro YAMASHITA
Clinical Endoscopy 2023;56(5):594-603
Background/Aims:
The necessity for pharyngeal anesthesia during upper gastrointestinal endoscopy is controversial. This study aimed to compare the observation ability with and without pharyngeal anesthesia under midazolam sedation.
Methods:
This prospective, single-blinded, randomized study included 500 patients who underwent transoral upper gastrointestinal endoscopy under intravenous midazolam sedation. Patients were randomly allocated to pharyngeal anesthesia: PA+ or PA– groups (250 patients/group). The endoscopists obtained 10 images of the oropharynx and hypopharynx. The primary outcome was the non-inferiority of the PA– group in terms of the pharyngeal observation success rate.
Results:
The pharyngeal observation success rates in the pharyngeal anesthesia with and without (PA+ and PA–) groups were 84.0% and 72.0%, respectively. The PA– group was inferior (p=0.707, non-inferiority) to the PA+ group in terms of observable parts (8.33 vs. 8.86, p=0.006), time (67.2 vs. 58.2 seconds, p=0.001), and pain (1.21±2.37 vs. 0.68±1.78, p=0.004, 0–10 point visual analog scale). Suitable quality images of the posterior wall of the oropharynx, vocal fold, and pyriform sinus were inferior in the PA– group. Subgroup analysis showed a higher sedation level (Ramsay score ≥5) with almost no differences in the pharyngeal observation success rate between the groups.
Conclusions
Non-pharyngeal anesthesia showed no non-inferiority in pharyngeal observation ability. Pharyngeal anesthesia may improve pharyngeal observation ability in the hypopharynx and reduce pain. However, deeper anesthesia may reduce this difference.