1.A study of sports injuries and behavior of handball players seeking medical advice after the injury. I: About the injury situation japanese and korean teams.
YOUNGMI LEE ; TAKEO NAKAGAWA ; TAKAYUKI MIURA
Japanese Journal of Physical Fitness and Sports Medicine 1998;47(5):517-524
The purpose of this study is to obtain more information about the occurrence of sports injury and through this to prevent injury in handball players.
Aquestionnaire was delivered to Japanese and Korean company handball players totaling 244 women (8 Japanese teams, 136 women and 7 Korean teames, 108 women), during the period from December, 1996 through March, 1997. The return rate was 88.9%. Injury rate in Korean teams was 73.2% and 71.7% in Japanese teams ; no statistical differences were found among these two countries. The injury rate was high on ankle joint, knee joint and lumbar in that order. Korean teams presented higher occurrence of jumper's knee and stress fracture.
2.A study of sports injuries and behavior of handball players seeking medical advice after the injury. II: Comparison of sequela occurence between japanese and korean teams.
YOUNGMI LEE ; TAKEO NAKAGAWA ; TAKAYUKI MIURA
Japanese Journal of Physical Fitness and Sports Medicine 1998;47(5):543-548
A study was conducted to clarify the occurrence of injuries among Japanese and Korean handball players, their present condition, and the response to prescribed treatments. It was also ascertained whether players, after receiving proper treatment, were less susceptible to injury sequelae. A questionnaire was delivered to Japanese and Korean company handball players totaling 244 women (8 Japanese teams, 136 women ; 7 Korean teams, 108 women), during the period from December 1996 through March 1997.
The rate of injuries and the treatment situation during and after the period when the injury was sustained, and the occurrence of sequelae in the lower limbs after the player had joined the team, were examined, and a comparison between the two countries was made. The return rate was 88.9%.
1. The emergency treatment rate after injury was similar in the twe countries. However, Japanese players usually used taping and cooling, whereas Korea players used heat treatment. 2. Both Japanese and Korean players' injuries were diagnosed at hospital, although Koreans also went to bonesetters. 3. Japanese players resumed playing upon receiving their doctors' consent, whereas some Korean players were forced to resume playing before fully recovering ; there was a significant difference between the two countries. 4. Many players in both countries, resumed playing even though they felt pain in daily life. 5. Players who had undergone cooling treatment immediately after the injury, and who resumed activities upon their doctors' consent, and only after the pain had disappeared during daily life, had a lower incidence of sequelae.
3.EFFECT OF TWO PASSIVE STRETCHING METHODS FOR TRICEPS SURAE ON DORSIFLEXION OF ANKLE JOINT
TAKAYUKI INAMI ; TAKUYA SHIMIZU ; HIROFUMI MIYAGAWA ; MASAYUKI INOUE ; TAKEO NAKAGAWA ; FUJIMARU TAKAYANAGI ; SHIGEO NIWA
Japanese Journal of Physical Fitness and Sports Medicine 2010;59(5):549-554
Stretching for the triceps surae muscle in the knee flexed position (medical stretching: MS) and knee extended position (static stretching: SS) were performed and the effect on the dorsiflexion angle of the ankle joint was examined. Five elderly females were selected as subjects. We measured the maximal dorsiflexion angle of the ankle joint in the following leg positions: (1) the maximal dorsiflexion angle in the extended knee position (EDF angle) and (2) the maximal dorsiflexion angle in the 90°flexed-knee position (FDF angle). There was a significant increase in the maximal dorsiflexion angle after MS and SS were carried out (p<0.01), but there was no significant difference between MS and SS. It was concluded that MS for triceps surae is equally effective as SS in increasing the maximal dorsiflexion angle of the ankle joint.
4.Association of hypertension with changes in the body mass index of university students.
Akira UCHIYAMA ; Takuya SHIMIZU ; Takeo NAKAGAWA ; Toyoho TANAKA
Environmental Health and Preventive Medicine 2008;13(5):271-280
BACKGROUNDThere are few longitudinal studies on the associations of obesity with hypertension in young adults.
OBJECTIVESTo analyze longitudinally to what extent weight gain associates with hypertension in young adults.
METHODSThe subjects of this study consisted of 6,178 university students (male 4,098; female 2,080). The associations of hypertension with body type change were longitudinally examined by using the records of health examinations while at university. The prevalence ratios (PRs) for hypertension in their senior year were calculated on groups that changed toward obese against those that changed toward underweight. The logistic regression analyses were used to estimate odds ratios (ORs) for hypertension in their senior year of each factor. The analyses were conducted on (i) all subjects, (ii) non-hypertensive subjects in their freshman year, and (iii) by schools, in order to take into account physical activities.
RESULTSThe PRs of hypertension in subjects changed toward obese from their freshmen to seniors against ones toward underweight were 1.47 (95% CI; 1.00-2.15) for males and 3.50 (0.93-13.22) for females. In analyses limited to non-hypertensive subjects in their freshman year, results were similar to those of all subjects. The analyses by school also showed similar results to those including all subjects. In logistic regression analyses, although the factor most strongly associated with hypertension was body type in their senior year, the body type in their freshman still showed significant association with hypertension after the adjustment of senior year body type and hypertension in freshman year. The ORs for hypertension in obese subjects to normal weight ones in their senior year were 9.13 (95% CI; 5.77-14.45) for males and 22.59 (5.69-89.67) for females after adjusted by hypertension in freshman, body type in freshman and school.
CONCLUSIONSThese data suggest that the increase of BMI is linked to hypertension in university students.
5.Cryopreservation of mouse resources
Toru TAKEO ; Satohiro NAKAO ; Yoshiko NAKAGAWA ; Jorge M. SZTEIN ; Naomi NAKAGATA
Laboratory Animal Research 2020;36(3):152-157
The cryopreservation of sperm and embryos is useful to efficiently archive valuable resources of genetically engineered mice. Till date, more than 60,000 strains of genetically engineered mice have been archived in mouse banks worldwide. Researchers can request for the archived mouse strains for their research projects. The research infrastructure of mouse banks improves the availability of mouse resources, the productivity of research projects, and the reproducibility of animal experiments. Our research team manages the mouse bank at the Center for Animal Resources and Development in Kumamoto University and continuously develops new techniques in mouse reproductive technology to efficiently improve the system of mouse banking. In this review, we introduce the activities of mouse banks and the latest techniques used in mouse reproductive technology.
6.Existence of a Neuropathic Pain Component in Patients with Osteoarthritis of the Knee.
Seiji OHTORI ; Sumihisa ORITA ; Masaomi YAMASHITA ; Tetsuhiro ISHIKAWA ; Toshinori ITO ; Tomonori SHIGEMURA ; Hideki NISHIYAMA ; Shin KONNO ; Hideyuki OHTA ; Masashi TAKASO ; Gen INOUE ; Yawara EGUCHI ; Nobuyasu OCHIAI ; Shunji KISHIDA ; Kazuki KUNIYOSHI ; Yasuchika AOKI ; Gen ARAI ; Masayuki MIYAGI ; Hiroto KAMODA ; Miyako SUZKUKI ; Junichi NAKAMURA ; Takeo FURUYA ; Gou KUBOTA ; Yoshihiro SAKUMA ; Yasuhiro OIKAWA ; Masahiko SUZUKI ; Takahisa SASHO ; Koichi NAKAGAWA ; Tomoaki TOYONE ; Kazuhisa TAKAHASHI
Yonsei Medical Journal 2012;53(4):801-805
PURPOSE: Pain from osteoarthritis (OA) is generally classified as nociceptive (inflammatory). Animal models of knee OA have shown that sensory nerve fibers innervating the knee are significantly damaged with destruction of subchondral bone junction, and induce neuropathic pain (NP). Our objective was to examine NP in the knees of OA patients using painDETECT (an NP questionnaire) and to evaluate the relationship between NP, pain intensity, and stage of OA. MATERIALS AND METHODS: Ninety-two knee OA patients were evaluated in this study. Pain scores using Visual Analogue Scales (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), painDETECT, duration of symptoms, severity of OA using the Kellgren-Lawrence (KL) system, and amount of joint fluid were evaluated and compared using a Spearman's correlation coefficient by rank test. RESULTS: Our study identified at least 5.4% of our knee OA patients as likely to have NP and 15.2% as possibly having NP. The painDETECT score was significantly correlated with the VAS and WOMAC pain severity. Compared with the painDETECT score, there was a tendency for positive correlation with the KL grade, and tendency for negative correlation with the existence and amount of joint fluid, but these correlations were not significant. CONCLUSION: PainDETECT scores classified 5.4% of pain from knee OA as NP. NP tended to be seen in patients with less joint fluid and increased KL grade, both of which corresponded to late stages of OA. It is important to consider the existence of NP in the treatment of knee OA pain.
Aged
;
Aged, 80 and over
;
Female
;
Humans
;
Knee/pathology/physiopathology
;
Male
;
Middle Aged
;
Neuralgia/*physiopathology
;
Osteoarthritis, Knee/*physiopathology
7.Survey on the Utilization of In-Hospital Formulation 10% Lidocaine Gel for Neuropathic Pain
Monami ARIFUKU ; Yuki SHIGETSURA ; Takeo YAMAGIWA ; Karin KATO ; Noriaki KITADA ; Satoshi IMAI ; Takayuki NAKAGAWA ; Tomohiro TERADA
Japanese Journal of Drug Informatics 2023;25(3):115-123
Objective: In many medical institutions in Japan, 10% lidocaine gel is prepared as an in-hospital formulation to treat intractable neuropathic pain. Clinical studies have reported the short-term efficacy of topical lidocaine therapy for neuropathic pain, while there are few reports in real-world practice. To clarify the clinical usage and its usefulness, in this study, we investigated the duration of use, amount, effectiveness, and safety of 10% lidocaine gel.Design: We conducted a retrospective study investigating the actual usage of 10% lidocaine gel using electronic medical records.Methods: This study included 74 patients treated with 10% lidocaine gel in Kyoto University Hospital between July 2019 and January 2022. Information about disease (purpose of use), concomitant medications and other background information of the patients were collected. In addition, the duration of use, amount, adverse events, and discontinuation of 10% lidocaine gel were investigated. Effectiveness was determined by physician interviews and the pain visual analogue scale (VAS).Results: Ten percent lidocaine gel was used primarily to treat postherpetic neuralgia and, in some cases, other types of chronic pain for a median duration of use of 3.2 months (0.03-118.5). Pain relief was achieved in 73.3% of patients according to physician interviews, with a significant decrease in the VAS score. Although adverse events were observed in 12 patients (16.2%), including skin problems (12.2%), paralysis (4.1%), and somnolence (1.4%), eight patients continued to use 10% lidocaine gel after their occurrence. Three patients discontinued it due to adverse events, and their symptoms subsequently improved thereafter.Conclusion: The present results suggest that 10% lidocaine gel is effective and safe even when used for a long-time. Although this is a single-center study, it is the first systematic investigation of real-world usage of an in-hospital formulation of 10% lidocaine gel and is expected to assist clinical practice and drug development.
8.Delayed surgical site infection after posterior cervical instrumented surgery in a patient with atopic dermatitis: a case report
Hiroshi TAKAHASHI ; Yasuchika AOKI ; Shinji TANIGUCHI ; Arata NAKAJIMA ; Masato SONOBE ; Yorikazu AKATSU ; Junya SAITO ; Manabu YAMADA ; Yasuhiro SHIGA ; Kazuhide INAGE ; Sumihisa ORITA ; Yawara EGUCHI ; Satoshi MAKI ; Takeo FURUYA ; Tsutomu AKAZAWA ; Masao KODA ; Masashi YAMAZAKI ; Seiji OHTORI ; Koichi NAKAGAWA
Journal of Rural Medicine 2020;15(3):124-129
Objective: Atopic dermatitis (AD) is one of the known risk factors for Staphylococcus aureus infection. The authors report the case of a patient with cervical spondylosis and AD who developed delayed surgical site infection after posterior cervical instrumented surgery.Patient: A 39-year-old male presented to our hospital with paralysis of the left upper extremity without any cause or prior injury. He had a history of severe AD. We performed C3–C7 posterior decompression and instrumented fusion based on the diagnosis of cervical spondylotic amyotrophy. One year after surgery, his deltoid and bicep muscle strength were fully recovered. Nevertheless, his neck pain worsened 2 years after surgery following worsening of AD. One month after that, he developed severe myelopathy and was admitted to our hospital. Radiographic findings showed that all the screws had loosened and the retropharyngeal space had expanded. Magnetic resonance imaging and computed tomography showed severe abscess formation and destruction of the C7/T1 vertebrae.Result: We diagnosed him with delayed surgical site infection. Methicillin-resistant Staphylococcus aureus was identified on abscess culture. The patient responded adequately to treatment with antibiotic therapy and two debridements and the infection subsided.Conclusion: We should consider the possibility of delayed surgical site infection when conducting instrumented spinal surgery in patients with severe AD.