The man aged 31, who had attempted suicide by taking poison of the herbicide PARAQUAT, died of its toxicity 12 hours later.In 3 hours of his hospitalization, the blood chemistry examination showed slight hepatic and renal failure and abnormality of electrolite in the serum.The examinations of E. C. G., X-ray, urine and stool could not be studied for shortness of his hospitalization.
At the time of post-mortem examination, for the chemical assay of PARAQUAT a piece of tissue was cut out from each organ, which were demonstrated in the liver, kidney, and contents of the stomach and intestine.At autopsy, the marked atrophy of the adrenal gland, congestion and edema of the lung, corrosive inflammation of the gastrointestinal tract, and degeneration of the liver and kidney were recognized.Clear toxic findings were not evident on gross appearance.Microscopically, the zonal necrosis in the adrenal, toxic neuropathia, focal degeneration and cytolytic necrosis in the liver, kidney and gastrointestinal mucosa, heavy congestion and edema of the lung, and slight fatty degeneration of the liver were noted.
The pathohistological appearance of poisoning by herbicide was compared with that of insecticide on other reports.And in present report, it was discussed that the toxicity of PARAQUAT may exhibit the similar findings as that of other organic chlorinated hydrocarbons.

Objective: It has been recognized that most medical institutions preferred the printed medium for their information sheets for patient education of inhaler usage. However, some questions have arisen. In a case where patients are not sufficiently informed of drug administration guidance due to limited information with only pictures and text, they might not be able to obtain a proper understanding. Contrarily, it is assumed that video medium, with audio and visual elements, is a format for education conveying a larger amount of information. We conducted comparative research regarding patient’s degree of understanding of inhalation guidance, comparing two groups of print- and video-medium-based instructions for inhaler usage and examined how effective two types of media explanations were on patients.Methods: Research participants were thirty persons visiting Jinjo Pharmacy, who were randomly assigned to the print medium group and the video medium group. After one group read and saw an explanation sheet of an inhaler where the maker wrote inhalation instructions and the other group watched an instruction video, the two groups practiced inhaler usage. Evaluation was performed with specified items and comprehensive assessment, and in addition, the time required for inhalation was measured.Results: Score of the evaluation score was statistically significantly higher in the video medium group than in the print medium group in score of specified items and score of comprehensive assessment, and was also significantly shorter in the operation time of the inhaler.Conclusion: This study clarified that the video medium group had fewer improper inhalation occurrences and shorter operation time and, therefore, showed the effectiveness of the video medium. It is recommended that the video medium should be actively utilized,which could improve patient medication adherence. Accessibility is required for patient education to achieve inhaler techniques by watching video-based instruction.