We perform color Doppler scanning for all patients with leg varix as a preoperative examination. We discovered a case of leg varix with inverse placement of femoral artery and vein by color Doppler scanning and comfirmed it by operation. A 69-year-old female was admitted with a 30-year history of bilateral leg varix and with leg skin ulcer and dermatitis. Color Doppler scanning showed that the femoral vein was lateral to the femoral artery and that the great saphenous vein crossed over the femoral artery from medial side. This was confirmed on operation. This is the first report of this anomaly in Japan.