There are many reports on the therapeutic effects of medcation on experimental ulcers however as yet a definitive drug therapy has not been found. Reports concerning the therapeutic results of acupuncture are almost unheard of. We examined hist-morphologcally the influences of acupuncture acupoint stimulation on acetic-acid serosa-searing ulcers in rats. We used as a reference for experimental ulcers the methods of nationwide medical investigators. A flatiron heated to a temperature of 90°C was placed on top of a 3mm. paper which had been saturated with acetic acid to create an acetic serosa searing ulcer. A laporotomy was performed under ethyl anesthesia and the ulcer creating operation performed. The 3rd day after treatment was considered the starting point of therapeutic progress. From this day for 5 days (5 treatments) the amount of cure resulting in the acupuncture stimulation group was compared with that in a non-stimulation control group. There were over 10 cases. The form of the ulcer in the membraneous stomach areas was cut in paraffin and histologically comparatively examined. Acupuncture stimulation was administered at ST-36 and BL-21 from the ptints effective in the treatment of stomach disease. The results of the experiment indicated that cure in the acupuncture stimulation group surpassed that in the control group.