1.Retrospective Study of The Outcome of Primary Repair of Arteriovenous Fistula (AVF) Aneurysm and Pseudoaneurysm in Secondary Hospital Setting (Kajian Retrospektif Pembaikian Primer Ateriovenous Fistula (AVF) Aneurisma dan Pseudoaneurisma di Hospital Sekunder)
Ong Xin Zen ; Ling Li Fan ; Philip Ding Hsin Loong ; Chong Kar Hon ; Goh Neng Xiang
Malaysian Journal of Health Sciences 2023;21(No.1):9-14
Aneurysms and pseudoaneurysm are commonly encountered with arteriovenous vascular access for haemodialysis.
They are difficult complications to manage. Due to the limited number of vascular centers available, patients were
unable to seek treatment until further complications arise. The technique of partial aneurysmectomy and primary repair
was adopted as the method of repair in this study. A total of 20 cases underwent the surgery from 2019 to 2020. Among
the 20 cases, one patient had two pseudoaneurysms at different location which requires her to undergo the procedure
twice. The successful cannulation rate post repair was 70% whereas the overall complication rate was 35% which might
be attributed to the small sample size. Overall, this study demonstrated that AVF aneurysm and pseudoaneurysm can be
safely treated with this approach and can be done effectively in non-vascular centers by general surgeons.
2.IVIM-DWI combined with MRS in differential diagnosis of osteoporotic fractures and metastatic vertebral compression fractures
Qiuju FAN ; Hui TAN ; Nan YU ; Qi YANG ; Shaoyu WANG ; Taiping HE ; Yong YU ; Yu XUE
Chinese Journal of Medical Imaging Technology 2018;34(2):297-301
Objective To explore the value of intravoxel incoherent motion DWI (IVIM-DWI) combined with single-voxel MRS in distinguishing osteoporotic fractures from metastatic vertebral compression fractures.Methods Totally 70 patients with vertebral compression fractures,who underwent CT scanner were enrolled.The patients were divided into osteoporotic group or metastatic group based on pathological results or clinical follow-up.All patients underwent conventional sagittal T1W,T2W,STIR,IVIM-DWI and single-voxel MRS scanning.Relative peak areas of the signal of water at 4.7 ppm and lipid at 1.3 ppm were determined.IVIM-DWI parameters (diffusion coefficient [D],pseudo diffusion [D*],perfusion fraction [f]) and MRS parameters (lipid water ratio [LWR],fat fraction [FF]) were also recorded.The diagnostic performance of MRS,IVIM-DWI,as well as MRS combined with IVIM-DWI in distinguishing osteoporotic fractures from metastatic vertebral compression fractures were evaluated by using ROC curve,and the area under curve (AUC) was calculated.Results The f,D and FF in metastatic group were significantly lower than those in osteoporotic group,while D* in metastatic group was significantly higher than that in osteoporotic group (all P<0.05).The sensitivity,specificity and accuracy in differentiating osteoporotic fractures from metastatic vertebral compression fractures was 87.50% (28/32),57.89 (22/38) and 71.43% (50/70) of MRS,78.13% (25/32),89.47% (34/38) and 84.28% (59/70) of IVIM-DWI,90.63% (29/32),97.37% (37/38) and 94.29% (66/70) of MRS combining with IVIM-DWI,respectively.AUC of MRS,IVIM-DWI,as well as MRS combined with IVIM-DWI was 0.73,0.88 and 0.94 (all P <0.05),respectively.Conclusion Combination of IVIM-DWI and MRS can improve the diagnostic efficiency of differentiating osteoporotic fractures from metastatic vertebral compression fractures.
3.Practice of relieving emergency overcrowding in Peking Union Medical College Hospital
Jihai LIU ; Xianlin HAN ; Taiping ZHANG ; Quan LIAO ; Xisheng WENG ; Huadong ZHU ; Qing CHANG ; Hui PAN ; Na GUO ; Zhanjie ZHANG ; Yafang LI ; Di SHI ; Fan LI ; Pengxia SUN ; Jun XU ; Wenming WU ; Shuyang ZHANG
Chinese Journal of Hospital Administration 2021;37(6):518-521
Peking Union Medical College Hospital, as one of the most stressful medical institutions in China, is facing the problem of emergency department overcrowding. In order to effectively alleviate the emergency overcrowding, improve the medical quality and patients′ medical experience, the hospital firmly grasped the two incremental links of " throughput" and " output" factors, established a multidisciplinary and multi-department cooperation team, constructed a close medical alliance cooperation mode, and innovated and explored a harmonious emergency overcrowding relief mode with the goal of unblocking the " exit" of patients. The practice showed that the comprehensive measures could effectively alleviate the problem of emergency overcrowding, and improve the medical environment and medical quality.
4.Pharmacological importance of Kunxian Capsule in clinical applications and its adverse effects: A review.
Ruijiao MA ; Maharajan KANNAN ; Kaiyan ZHUANG ; Qing XIA ; Dong SUN ; Pengfei TU ; Taiping FAN ; Kechun LIU ; Yun ZHANG
Chinese Herbal Medicines 2023;15(2):222-230
Kunxian Capsule (KX) is a popular Chinese patent medicine for the treatment of rheumatoid arthritis, nephrotic syndrome, systemic lupus erythematosus, Henoch-Schönlein purpura, ankylosing spondylitis, psoriatic arthritis and eczema. However, there is scarcity of comprehensive information on the significance of KX in the clinical application and its side effects. Hence, it is aimed to provide a review of the significance of KX, with a focus on the pharmacological effects, clinical applications, and its adverse reactions. This review was based on the published literatures in PubMed, China National Knowledge Infrastructure and WanFang database. The articles were collected by two independent authors with no time limits applied until November 30, 2022. The search term includes Kunxian Capsule and/or clinical effect, pharmacology, disease, therapy, adverse effects and quality control. KX has been shown to be effective in the treatment of autoimmune arthritis by inhibiting inflammatory responses and inducing apoptosis. Many studies suggest that KX has anti-inflammatory and analgesic properties that aid in the improvement of joint functions. KX dispels wind, removes dampness, invigorates the kidneys, and promotes blood circulation, thereby curing various diseases. However, studies also suggest KX-related adverse reactions in multiple systems. Overall, this review highlights the scientific basis of KX in curing or preventing various diseases and provides novel insights for further research and clinical applications.