1.AIDS-related recognition among the general population in Korea.
Be Long CHO ; Byung Goog YANG ; Hoon Ki PARK ; Seong Won KIM ; Tai Woo YOO ; Bong Yul HUH
Journal of the Korean Academy of Family Medicine 1993;14(10):670-679
No abstract available.
Korea*
2.Local exposure of 849 MHz and 1763 MHz radiofrequency radiation to mouse heads does not induce cell death or cell proliferation in brain.
Tae Hyung KIM ; Tai Qin HUANG ; Ja June JANG ; Man Ho KIM ; Hyun Jeong KIM ; Jae Seon LEE ; Jeong Ki PACK ; Jeong Sun SEO ; Woong Yang PARK
Experimental & Molecular Medicine 2008;40(4):477-477
3.The monitoring Case Analysis of Nutrition-related Programs Presented on Television Broadcast Media.
Hea Sook RYU ; Hyun Sook KIM ; Il Sun YANG ; Ki Tai KIM ; Mi Yong BAE
Journal of the Korean Dietetic Association 2003;9(2):138-148
The purpose of this study was to analyze information about food and nutrition topics presented throughout the television broadcast media, thereby suggest the optimal communication method to give right information to the general public. To perform this study, total sixteen monitoring people were recruited and trained through monitoring practice before and during the study. Five domestic TV channels were selected to be monitored, for six months. For the best efficiency, all the monitoring people were divided into 8 teams based on the regional consideration. The statistical analysis of data was completed using SAS program. The main results of this study are as follows. First, the total reporting cases of information about foods and nutrition were 237 , among which about 30% was classified as appropriate and 70% as inappropriate based on the trained monitors' evaluation. Second, the analysis of contents about incorrect informations showed that the insufficient descriptions of terminology and contents were the highest. And insufficient scientific evidences, incorrect contents excessively entertainment-oriented, no provision of alternatives , improper selection of expert advisors were followed. These results suggest that systematical monitoring should be continued to reduce the frequency of incorrect communication thereby give the right information in food and nutrition area to the general public. And there should be a closely cooperated system to provide the professional information to broadcasting production team by establishing the strategic program. In order to do that, most importantly the advisory team should be organized to professionally connect mass media to corresponding specialists. In addition, more educational programs about food and nutrition should be developed to provide right information to the general public.
Mass Media*
;
Specialization
;
Television*
4.The monitoring Case Analysis of Nutrition-related Programs Presented on Television Broadcast Media.
Hea Sook RYU ; Hyun Sook KIM ; Il Sun YANG ; Ki Tai KIM ; Mi Yong BAE
Journal of the Korean Dietetic Association 2003;9(2):138-148
The purpose of this study was to analyze information about food and nutrition topics presented throughout the television broadcast media, thereby suggest the optimal communication method to give right information to the general public. To perform this study, total sixteen monitoring people were recruited and trained through monitoring practice before and during the study. Five domestic TV channels were selected to be monitored, for six months. For the best efficiency, all the monitoring people were divided into 8 teams based on the regional consideration. The statistical analysis of data was completed using SAS program. The main results of this study are as follows. First, the total reporting cases of information about foods and nutrition were 237 , among which about 30% was classified as appropriate and 70% as inappropriate based on the trained monitors' evaluation. Second, the analysis of contents about incorrect informations showed that the insufficient descriptions of terminology and contents were the highest. And insufficient scientific evidences, incorrect contents excessively entertainment-oriented, no provision of alternatives , improper selection of expert advisors were followed. These results suggest that systematical monitoring should be continued to reduce the frequency of incorrect communication thereby give the right information in food and nutrition area to the general public. And there should be a closely cooperated system to provide the professional information to broadcasting production team by establishing the strategic program. In order to do that, most importantly the advisory team should be organized to professionally connect mass media to corresponding specialists. In addition, more educational programs about food and nutrition should be developed to provide right information to the general public.
Mass Media*
;
Specialization
;
Television*
5.Chronic Spinal Epidural Abscess after Epidural Analgesia: Case Report.
Tai Ki YANG ; Keun Su KIM ; Jung Chung LEE
Journal of Korean Neurosurgical Society 2003;33(6):599-601
Three cases of chronic spinal epidural abscess following spinal epidural analgesia are presented. Spinal epidural abscess is a relatively rare infectious disease. It has recently increased in frequency due to the increased use of epidural steroid injections and epidural analgesia. It is very difficult to detect the spinal epidural abscess from its variable symptoms. So, it is important in making a diagnosis of epidural abscess to take into account the previous history of epidural analgesia.
Analgesia, Epidural*
;
Communicable Diseases
;
Diagnosis
;
Epidural Abscess*
6.Analysis of Gene Expression in the Human Chorion of Preterm Labor Using cDNA Microarray.
Hyun Sun KO ; Yeun Hee KIM ; Ki Cheol KIL ; Dong Eun YANG ; In Yang PARK ; Sa Jin KIM ; Tai Churl PARK ; Jong Chul SHIN
Korean Journal of Perinatology 2006;17(2):204-216
OBJECTIVE: We used a genome-wide approach to identify differentially expressed genes in patients with preterm delivery caused by preterm labor to improve the understanding of underlying molecular mechanism. METHODS: RNA was isolated from the chorions of patients with preterm delivery caused by preterm labor with intact membranes and term vaginal delivery. cDNA microarray experiments were used to identify differentially expressed genes, and reverse transcriptase-polymerase chain reaction was used in follow-up experiment. RESULTS: cDNA microarray experiments identified significantly increased expression of 104 genes and decreased expression of 102 genes in the preterm cases. 18 genes showed more than 1.5-fold increased expressions in the chorions of patients with preterm delivery by preterm labor than those with term vaginal delivery. In preterm delivery, up-regulated genes were associated with cell adhesion, cell cycle regulation, development, transport, morphogenesis, muscle contraction, signal transduction, and transcription. 15 genes showed more than 1.5-fold decreased expressions in chorions of patients delivered preterm by preterm labor than delivered term by labor. In preterm delivery, down-regulated genes were associated with cell differentiation, development, metabolism, morphogenesis, RNA processing, signal transduction, transcription, and transport. CONCLUSION: This study suggests cDNA microarray technique might provide insights into the molecular basis of preterm delivery caused by preterm labor.
Cell Adhesion
;
Cell Cycle
;
Cell Differentiation
;
Chorion*
;
DNA, Complementary*
;
Female
;
Follow-Up Studies
;
Gene Expression*
;
Humans*
;
Membranes
;
Metabolism
;
Morphogenesis
;
Muscle Contraction
;
Obstetric Labor, Premature*
;
Oligonucleotide Array Sequence Analysis*
;
Pregnancy
;
RNA
;
Signal Transduction
7.Difference of Fibroblast Growth Factor Receptor-1(FGFR-1) and Progesterone Receptor(PR) Expression between Classic and Aggressive Meningiomas.
Tai Hyoung CHO ; Jung Yul PARK ; Yang Suk CHAI ; Youn Kwan PARK ; Yong Gu CHUNG ; Hung Seob CHUNG ; Hoon Kap LEE ; Ki Chan LEE
Journal of Korean Neurosurgical Society 1996;25(8):1555-1560
Fibroblast growth factor(FGF) is a mitogen and a potent antigenic factor. It is also known as a differentiation factor for neuroectodermal-derived cell. It has been observed to be expressed in more than 90% of m-RNA of human meningiomas and gliomas. Progesterone receptor(PR) is well known surface receptor of meningioma and its number is greater than that of estrogen receptor. It is one os the known prognostic factors of meningioma. Meningiomas themselves are regarded as benign tumors in general, however some types show aggressive features. In the present study, authors examined the expression of FGF-1 and PR in meningioma tissues using immunohistochemical techniques with monoclonal antibody against human FGF-1 and PR. FGF-1 was detected in 25 of 35 classic meningiomas and in 7 of 9 aggressive ones. PR is expressed in 5 cases of classic and 2 cases of aggressive meningiomas. These results suggest FGF-1 may be involved in aggressive progression of meningioma. There was no significant difference of aggressiveness and expression of FGFR-1 and PR between classic and aggressive meningiomas, including their subtypes.
Estrogens
;
Fibroblast Growth Factor 1
;
Fibroblast Growth Factors*
;
Fibroblasts*
;
Glioma
;
Humans
;
Meningioma*
;
Progesterone*
8.Search for Differentially Expressed Genes in Preterm Human Placentae and Their Membranes by Annealing Control Primer System.
Hyun Sun KO ; Yeun Hee KIM ; Ki Cheol KIL ; Ju Hee JEONG ; Dong Eun YANG ; Dae Young CHUNG ; Tai Churl PARK ; Soo Pyung KIM ; Jong Chul SHIN
Korean Journal of Perinatology 2005;16(4):300-308
OBJECTIVE: The aim of this study was to investigate the gene expression profiles using GeneFishingTM kit in human placentae and their membranes delivered at preterm caused by preterm labor. METHODS: Specimens were obtained from placenta, chorion, and amnion delivered at preterm and term, respectively. Total RNAs were isolated from each specimen. Thereafter, the profiles of expression genes between preterm and term specimens were compared using a new and accurate reverse transcription-polymerase chain reaction (RT-PCR) that involves annealing control primers (ACPs) to identify the genes expressed differentially and screened by basic local alignment search tool (BLAST) search. RESULTS: Using 20 ACPs, 13 differentially expressed genes (DEGs) were identified and sequenced. 7 of them were expressed up-regulation, while 6 were expressed down-regulation in preterm deliveries. A BLAST searches revealed that 11 were known genes and 2 were unknown genes. Among known genes, up-regulated genes were insulin-like growth factor II associated protein, vigilin, acyl-Coenzyme A dehydrogenase, tissue inhibitor of metalloproteinase 1 (TIMP1), ribosomal protein S26 (RPS26), follistatin-like 1 (FSTL1) and down-regulated genes were two mitochondrial DNAs, ribosomal protein S28 (RPS28), transglutaminase 2 (TGM2), heparin sulfate proteoglycan (HSPG, perlecan). CONCLUSION: This study shows that the ACP system is a good method for the identification of preterm-related genes. Furthermore, this study suggests that further analysis of the differentially expressed genes in preterm we have identified should provide insights into the molecular basis of preterm delivery caused by preterm labor.
Acyl-CoA Dehydrogenase
;
Amnion
;
Chorion
;
DNA, Mitochondrial
;
Down-Regulation
;
Female
;
Heparin
;
Humans*
;
Insulin-Like Growth Factor II
;
Membranes*
;
Obstetric Labor, Premature
;
Placenta*
;
Pregnancy
;
Proteoglycans
;
Ribosomal Proteins
;
RNA
;
Tissue Inhibitor of Metalloproteinase-1
;
Transcriptome
;
Up-Regulation
9.Solitary Spinal Osteochondroma Presenting as a Neck Mass: Case Report.
Se Hoon KIM ; Yong Gu CHUNG ; Tai Hyoung CHO ; Yang Seok CHAE ; Jung Keun SUH ; Ki Chan LEE ; Hoon Kap LEE
Journal of Korean Neurosurgical Society 1998;27(4):523-529
Osteochondroma, also known as osteocartilaginous exostosis or simply exostosis, comprises about 8.5% of all primary bone tumors and about 36% of those that are benign. Osteochondromas affect mostly the long bones; only 3% of solitary osteochondromas originate in the spine, while a solitary lesion in the cervical spine is distinctly rare. We present a case of osteochondroma of the upper cervical spine, presenting as a posterior neck mass. Although rare, spinal osteochondromas should be considered in the differential diagnosis of neck masses, and surgical treatment should be undertaken to correct secondary pain, disability, neurologic deficits, or cosmetic deformities.
Congenital Abnormalities
;
Diagnosis, Differential
;
Exostoses
;
Neck*
;
Neurologic Manifestations
;
Osteochondroma*
;
Spine
10.Efficacy and Safety of the Selective alpha1A-Adrenoceptor Blocker Silodosin for Severe Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia: A Prospective, Single-Open-Label, Multicenter Study in Korea.
Ki Hak MOON ; Phil Hyun SONG ; Dae Yul YANG ; Nam Cheol PARK ; Soo Woong KIM ; Sung Won LEE ; Sae Woong KIM ; Du Geon MOON ; Jong Kwan PARK ; Tai Young AHN ; Kwangsung PARK
Korean Journal of Urology 2014;55(5):335-340
PURPOSE: To evaluate the efficacy and safety of silodosin 8 mg once daily in a 12-week treatment of subjects with severe lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: A total of 100 subjects from 10 urology centers in Korea were included in this study. The inclusion criteria were as follows: age > or =50 years, International Prostate Symptom Score (IPSS) > or =20, quality of life (QoL) score > or =3, urine volume > or =120 mL and maximal urinary flow rate (Qmax) <15 mL/s, and postvoid residual volume (PVR) <100 mL. We assessed the improvement of LUTS with change in IPSS, QoL score, Qmax, PVR, and adverse events at baseline and 4 and 12 weeks after treatment with silodosin 8 mg once daily. RESULTS: The IPSS values were 23.27+/-3.34, 15.89+/-6.26, and 13.80+/-6.31 at baseline, 4, and 12 weeks, respectively, with significant improvements (p<0.0001, p=0.0214, respectively). QoL scores were 4.44+/-0.85, 3.38+/-1.20, and 3.04+/-1.20 at baseline, 4, and 12 weeks, respectively, and the differences were statistically significant (p<0.0001). There was a significant difference in Qmax between baseline and 12 weeks (p<0.0001) but not in PVR (p=0.9404) during the clinical trial. The most frequent adverse event in this study was ejaculation failure with 13 cases. However, no subject dropped out because of ejaculation failure, and in 12 of the 13 cases it was fully resolved without further treatment. CONCLUSIONS: Silodosin 8 mg once daily may be effective and safe in Korean patients with severe LUTS associated with BPH.
Ejaculation
;
Humans
;
Korea
;
Lower Urinary Tract Symptoms*
;
Male
;
Prospective Studies*
;
Prostate
;
Prostatic Hyperplasia*
;
Quality of Life
;
Residual Volume
;
Urology