1.Clinical Study of Urinary Tract Infection associated with Vesicouretral Reflux.
Kwang Hyun KIM ; Tai Jin PARK ; Woo Gill LEE
Journal of the Korean Pediatric Society 1984;27(5):467-474
No abstract available.
Urinary Tract Infections*
;
Urinary Tract*
2.A STUDY ON THE FACTORS AFFECTING TO TOOTH WEAR.
Hyun Bae PARK ; Tai Ho JIN ; Kyung Soo HAN
The Journal of Korean Academy of Prosthodontics 1999;37(3):328-342
This study was performed to investigate the factors related to tooth wear. For this study, 78 patients with temporomandibular disorders and 76 dental students without any signs and symptoms of temporomandibular disorders were selected as the patients group and as the normal group, respectively. Preferred chewing side, Angle's classification, lateral guidance pattern, head and shoulder posture wee observed clinically. Electromyographic activity of anterior temporalis and masseter muscle were recorded with BioEMG and occlusal status were recorded with T-Scan . Wear facet area of each tooth was measured from working model of upper arch corresponding to the occlusal status from T-Scan, Wear facet area were measured with planimeter in mm2. Total area were divided into incisal, canine, posterior tooth area. Anterior wearfacet area was incisor area plus canine area, and unilateral area was anterior area plus posterior area. The data collected were analyzed by SAS statistical program and the results of this study were as follows: 1. There was no significant difference between the two groups in total werafacet area, and male subjects showed tendency to have larger area in the normal group but female subjects showed tendency vice versa. 2. There was no significant difference related to preferred chewing side and Angle's classification, however, some difference was observed by lateral guidance pattern. Anterior wear facet area in subjects of canine guidance was the largest in the three subgroups. 3. Subjects with head tilting to right side had larger posterior and total area, and subjects with higher shoulder in right side had larger canine and anterior area than any other subgrous. 4. Electromyographic activity of masseter muscle was more correlated with wear facet area than anterior temporalis muscle, and tooth contact number and force were significantly correlated with wear facet area, but the most important factor affecting tooth attrition was age.
Dental Occlusion
;
Female
;
Head
;
Humans
;
Incisor
;
Male
;
Malocclusion
;
Masseter Muscle
;
Mastication
;
Posture
;
Shoulder
;
Students, Dental
;
Temporomandibular Joint Disorders
;
Tooth Attrition
;
Tooth Wear*
;
Tooth*
3.Effects of Sensory Denervation by Neonatal Capsaicin Treatment on Cytokine Production and Various Immune Responses.
Tai You HA ; Jeong Ho LEE ; Jae Seung PARK ; Hyun Ju HA ; Young Hyun KIM
Korean Journal of Immunology 1999;21(3):193-208
Capsaicin, the pungent principle of hot peppers, is a neurotoxin that depletes unmyelinated primary sensory neurons (polymodal nociceptors) of neuropeptides like tachykinins. However, the role of capsaicin-sensitive sensory nerve in the production of cytokines, penicillin V (PEV)-induced active fatal anaphylaxis and other immune responses is not yet fully established. Neonatal mice were pretreated s.c. with a single injection of 10 ug of capsaicin per mouse in volume of 20 ul within 5 days of age. Using 5-8 week old mice pretreated as neonates with capsaicin, the capsaicin- pretreated and vehicle-treated control mice were examined for various parameters of immune responses described above. For the induction of active fatal anaphylaxis with PEV, 8 week old mice pretreated as neonates and age-matched capsaicin- untreated control mice were sensitized i.p. with 500 ug of PEV-ovalbumin conjugate plus 2*10(9) B. pertussis and 1.0 mg alum and challenged i.v. with PEV-bovine serum albumin conjugate 14 days later. It was found that neonatal capsaicin-pretreatment significantly enhanced contact hypersensitivity to TNCB and hemagglutination response to SRBC, but significantly inhibited the proliferation response of rnurine splenocyte to Con A and LPS. Interestingly, neonatal capsaicin pretreatment significantly inhibited the intensity of PEV-induced active fatal anaphylaxis and decreased the mortality due to anaphylactic shock. It also significantly inhibited LPS- induced production of cytokines such as TNF-a, IL-1B, IL-6, IL-10, and IL-12. The capsaicin-pretreatment also resulted in an inhibition of the activation of NF-kB. Taken together, these data showed for the first time that neonatal capsaicin-pretreatment significantly inhibited an antibiotic (PEV)-induced anaphylaxis and production of various cytokines, and suggest that capsaicin-sensitive primary sensory nerve may play an important regulatory role in active fatal anaphylaxis and cytokine production, thus potentially presenting tools for immune intervention. In particular, the data presented also indicated the possibility to selectively down-modulate cytokine production and NF-kB activation may offer a broad application for therapeutic intervention in neuroimmunological diseases and other pathological situations.
Anaphylaxis
;
Animals
;
Capsaicin*
;
Cytokines
;
Denervation*
;
Dermatitis, Contact
;
Hemagglutination
;
Humans
;
Infant, Newborn
;
Interleukin-10
;
Interleukin-12
;
Interleukin-6
;
Mice
;
Mortality
;
Neuropeptides
;
NF-kappa B
;
Penicillin V
;
Sensory Receptor Cells
;
Serum Albumin
;
Tachykinins
;
Whooping Cough
4.A Case Report of Congenital Hypoplastic Anemia.
Hyun Gi JUNG ; Tai Gyo WHANG ; In Soon PARK ; Chul Ho KIM ; Soon Yong LEE
Journal of the Korean Pediatric Society 1983;26(3):279-283
No abstract available.
Anemia, Hypoplastic, Congenital*
5.Nutritional Status of the Elderly Living in Cheongju - I. Health-Related Habits, Dietary Behaviors and Nutrient Intakes.
Ki Nam KIM ; Joung Won LEE ; young Sook PARK ; Tai Sun HYUN
Korean Journal of Community Nutrition 1997;2(4):556-567
The health-related habits dietary behaviors and nutrient intakes of the elderly living in Cheongju were investigated by interviews with a questionnaire from August to September in 1996. The responses of 169 free-living elderly aged over 65(male 91, female 78) were analyzed. Thirty-six percent of the subjects smoked currently, 33%, drank alcoholic beverages, and 52% exercise regularly. Exercise was mostly in the from of walking for 1/2-1 hour. Significantly higher proportions of males smoked, drank, and exercised as compared to females. Food groups eaten at every meal were examined on a 5-point scale, and the consumption scores were compared with groups according to sex, age, smoking, drinking, and exercise habits. The elderly who exercised regularly got significantly higher scores in their calcium intakes and the variety of the 6 food groups than the elderly who did not exercise. The dietary assessment data showed that the energy intakes of males and females were 81.9% and 72.8% of the RDAs, respectively. The proportions of the elderly consuming less than 75% of RDAs of vitamin A and calcium were 96.5% and 91.1% of the total subjects, respectively. Higher educational status, more pocket money and regular exercise had positive effects on nutrient intakes, while smoking and drinking among females, but not males, had negative effects. Therefore, to improve nutritional status of the elderly, intake of vitamin A-and calcium-rich food such as milk with regular exercise should be emphasized on the education program.
Aged*
;
Alcohol Drinking
;
Alcoholic Beverages
;
Calcium
;
Chungcheongbuk-do*
;
Drinking
;
Education
;
Educational Status
;
Female
;
Food Habits*
;
Humans
;
Male
;
Meals
;
Milk
;
Nutritional Status*
;
Smoke
;
Smoking
;
Vitamin A
;
Vitamins
;
Walking
;
Surveys and Questionnaires
6.Effect of dihydroergocristine(Unergol@) on supression of lactation.
Sang Cheon SEO ; Jin Wan PARK ; Tai Young HWANG ; Hyun Ho KIM ; Won Ki LEE
Korean Journal of Perinatology 1992;3(2):77-83
No abstract available.
Female
;
Lactation*
7.The clinical epidemiologic study of congenital anomalies in the newborn infants.
Hea Kyeong PARK ; Kae Hyun NAM ; Kwon Hae LEE ; Tai Ho CHO
Korean Journal of Perinatology 1991;2(1):58-67
No abstract available.
Epidemiologic Studies*
;
Humans
;
Infant, Newborn*
8.Effects of Capsaicin on Production of Cytokines and Nitric Oxide, Salmonella Infection and NF-kappa B Activation.
Tai You HA ; Suhn Young IM ; Jae Seung PARK ; Hyun Ju HA ; Du Young CHOI
Korean Journal of Immunology 1998;20(3):349-363
"Capsaicin, the pungent principle of hot peppers, is a neurotoxin that depletes primary sensory neurons of neuropeptides like tachykinin. The objectives of these experiment was to examine the effects of capsaicin on Salmonel/a typhimurium-induced production of cytokines such as TNF-a, IL-1B, IL-6, IL-10 and IL-12 and on production of nitric oxide in peritoneal macrophages. In addition, the effects of capsaicin on survival rates of S. typhimurium-infected mice and on nuclear transcription factor (NF-kB) activation were also investigated. Mice were pretreated with a single s.c. injection of 100 ug of capsaicin and were infected i.v. with S. typhimurium (5xO5/mouse) in 0.2 ml volume after capsaicin pretreatment. The serum cytokine levels were measured 30, 60, 120, 180 and 240 min after Salmonella infection, using ELISA kits. The activation of NF-B was also examined by gel shift assay in spleens, thymuses and brains of mice that had been pretreated with a single s.c. injection of 100 ug of capsaicin. It was found that Sa/mone/la infection induced the production of TNF-a, IL-1B, IL-6, IL-10 and IL-12, but capsaicin pretreatment inhibited the production of TNF-a, IL-1B, IL-10 and IL-12, but enhanced IL-6 production 120 min after Salmonella infection. Interestingly, the capsaicin pretreatment inhibited the activation of NF-kB in spleens and thymuses. There were no differences in the numbers of bacteria in livers, brains, spleens, kidneys and lungs between capsaicin- pretreated mice and the control animals in applied experimental conditions. Suprisingly, however, capsaicin pretreatment increased both the survival rates of Sa/mone//a-infected mice and production of nitric oxide by peritoneal macrophages compared with capsaicin-untreated control mice. Taken together, these results indicate that the capsaicin-sensitive primary sensory neurons may play an important modulatory role in the production of cytokine, nitric oxide and NF-B activation and the pathogenesis of salmonellosis."
Animals
;
Bacteria
;
Brain
;
Capsaicin*
;
Cytokines*
;
Enzyme-Linked Immunosorbent Assay
;
Interleukin-10
;
Interleukin-12
;
Interleukin-6
;
Kidney
;
Liver
;
Lung
;
Macrophages, Peritoneal
;
Mice
;
Neuropeptides
;
NF-kappa B*
;
Nitric Oxide*
;
Salmonella Infections*
;
Salmonella typhimurium
;
Salmonella*
;
Sensory Receptor Cells
;
Spleen
;
Survival Rate
;
Tachykinins
;
Thymus Gland
;
Transcription Factors
9.The effect of vaginal bleeding in the first half of pregnancy on outcome.
Jae Whan KWAK ; Jin Wan PARK ; Tai Young HWANG ; Hyun Ho KIM ; Won Ki LEE
Korean Journal of Obstetrics and Gynecology 1992;35(11):1577-1582
No abstract available.
Pregnancy*
;
Uterine Hemorrhage*
10.Cervical carcinoma with procidentia : a report of one case.
Jin wan PARK ; Tai Young HWANG ; Hyun Ho KIM ; Goo Hwa JE
Korean Journal of Obstetrics and Gynecology 1993;36(10):3662-3665
No abstract available.