1.Study on the cel biological properties of human ovarian mucinous cystadenocarcinoma cell line(RMUG) and two sublines(RMUG-S, RMUG-L).
Soo Hyoung SEO ; Soon Gone LEE ; Kwon Hae LEE ; Tai Ho CHO
Korean Journal of Obstetrics and Gynecology 1993;36(7):1931-1947
No abstract available.
Cystadenocarcinoma, Mucinous*
;
Humans*
;
Mucins*
2.Morphometric Analysis of the Pedicle of Lumbar Vertebrae Based on Radiologic Images in Koreans.
Tai Hyoung CHO ; Chang Sub UHM ; Im Joo RHYU
Korean Journal of Physical Anthropology 1997;10(2):243-250
The vertebral pedicle is an important structure used as an implant site for spinal instrumentation surgery. Since precise anatomical knowledge of lumbar pedicles in vivo is essential for risk - free surgery, we analyzed Korean vertebrae with radiologic imaging techniques. The authors analayzed 500 pedicles from L1 to L5 vertebrae with computerized tomograms (CT) and simple radiograms taken from patient free of vertebral abnormality. Five morphometric parameters: transverse pedicle width, transverse pedicle angle, sagittal pedicle width, sagittal pedicle angle depth to anterior cortex were measured. The transverse diameter and angle of pedicle increased gradually from L1 to L5, while the sagittal diameter and angle decreased from L1 to L5. The depth to anterior cortex from posterior elements was longer along the pedicle axis than along axis parallel to midline.
Axis, Cervical Vertebra
;
Humans
;
Lumbar Vertebrae*
;
Spine
3.Traumatic Cervical Cord Transection without Facet Dislocations-A Proposal of Combined Hyperflexion-Hyperextension Mechanism: A Case Report.
Yoo Hyun CHA ; Tai Hyoung CHO ; Jung Keun SUH
Journal of Korean Medical Science 2010;25(8):1247-1250
A patient is presented with a cervical spinal cord transection which occurred after a motor vehicle accident in which the air bag deployed and the seat belt was not in use. The patient had complete quadriplegia below the C5 level and his imaging study showed cervical cord transection at the level of the C5/6 disc space with C5, C6 vertebral bodies and laminar fractures. He underwent a C5 laminectomy and a C4-7 posterior fusion with lateral mass screw fixation. Previous reports have described central cord syndromes occurring in hyperextension injuries, but in adults, acute spinal cord transections have only developed after fracture-dislocations of the spine. A case involving a post-traumatic spinal cord transection without any evidence of radiologic facet dislocations is reported. Also, we propose a combined hyperflexion-hyperextension mechanism to explain this type of injury.
Accidents, Traffic
;
Adult
;
Cervical Vertebrae/*injuries/radiography/surgery
;
Fracture Fixation, Internal
;
Humans
;
Laminectomy
;
Male
;
Spinal Cord Injuries/etiology/*radiography/surgery
;
Tomography, X-Ray Computed
4.Intraspinal Epidermoid Tumor with Previous Lumbar Puncture.
Taek Hyun KWON ; Jung Keun SUH ; Tai Hyoung CHO ; Hoon Kap LEE
Journal of Korean Neurosurgical Society 1997;26(8):1145-1148
Congenital intraspinal epidermoid tumors, while rare, do occur ; that they are related to spinal puncture is less well understood. This article describes the case of a 10 year-old boy with intraspinal epidermoid tumor, who five years previously had undergone lumbar puncture. A striking clinical features of this case is pain in the lower extremity. In this report, we review the literature and discuss the probable developmental mechanism of such tumor.
Child
;
Humans
;
Lower Extremity
;
Male
;
Spinal Puncture*
;
Strikes, Employee
5.Surgical Experience with Craniopharyngioma.
Taek Hyun KWON ; Yong Gu CHUNG ; Tai Hyoung CHO ; Heung Seob CHUNG ; Ki Chan LEE ; Hoon Kap LEE
Journal of Korean Neurosurgical Society 1997;26(5):698-703
A retrospective review was performed of all patients with craniopharyngioma treated over a 6-year period. Of the 19 patients, 10 were males and 9 were females, with a mean age of 29 years(range 4 to 65 years). Their clinical follow-up periods ranged from 8 to 73 months, with a mean of 33.4 months. Eight patients(42%) were less than 18 years of age. In children, the most common symptoms were relared to increased intracranial pressure(100%), followed by short stature(50%), whereas visual disturbance(63.6%) was most common in adult. Obstructive hydrocephalus was observed in 7 patients(36.8%), and was more frequently developed in cases with larger tumor size and retrochiasmatic location. All patients were underwent for surgical removal and the most of the surgical procedures were carried out by the pterional or subfrontal approach. Total removal of the tumor was achieved in 8 patients(42.1%), and in 6 subtotally removed. Surgical outcome was favorable in 16 patients(84.2%), but 2 patients(10.5%) died in the postoperative period due to the hypothalamic dysfunction. Persistent diabetes insipidus requiring hormonal replacement therapy occurred in 8 patients(42.1%). Recurrence or regrowth of the tumor was observed in 5 patients(29. 4%). Recurrence was related with the extent of surgical resection.
Adult
;
Child
;
Craniopharyngioma*
;
Diabetes Insipidus
;
Female
;
Follow-Up Studies
;
Humans
;
Hydrocephalus
;
Male
;
Postoperative Period
;
Recurrence
;
Retrospective Studies
6.Clinical Analysis of Repeated Lumbar Disc Surgery.
Chang Soo LIM ; Tai Hyoung CHO ; Jung Yul PARK ; Hung Seob CHUNG ; Jung Keun SUH ; Hoon Kap LEE
Journal of Korean Neurosurgical Society 1996;25(8):1620-1625
Results from lumbar disc operation in general are favorable in 70% to 90% of patients. The rate of necessary reintervention of the primary discectomy, however, may be as high as one fifth of cases even though diagnostic and technical standards have been improved. The purpose of this study was to analyse the reasons for failure of primary discectomy and which factors might have influenced the outcome of revisions in 53 patients with failed back surgery syndrome from the years 1989 to 1993. Mean follow up duration was 11.4 months with range of 1 to 69 months. Before revisions, all patients had one or more lumbar disc operations in whom disabling pain, neurologic deficits, and/or lumbar instabilities have been persisted or newly developed. The most common intraoperative findings of patients with revision were recurrent or persistent disc material(35.9%) followed by incomplete decompression from previous operations(24.5%), and disc lesions at new level(11.3%). In overall, 77.3% of total patients showed satisfactor y results(fair, good, and excellent) but this figure drops to 39.6% when those with at least good or excellent outcomes are only considered as definitively improved. Moreover only 22.9% good results were obtained among 35 patients with those less than 6 months of symptom duration. As for the total number of operations undertaken, it can not be conclusively stated due to small numbers in each categories, but less favorable results have been observed in those with more than one revisions. The factors predicting good outcome from revisions in our series were:1) greater than 6 months of pain relief after primary operation, 2) sciatica more prominent than lower back pain, 3) fewer operations.
Decompression
;
Diskectomy
;
Failed Back Surgery Syndrome
;
Follow-Up Studies
;
Humans
;
Low Back Pain
;
Neurologic Manifestations
;
Sciatica
7.Adjacent Segment Instability after Posterior Lumbar Fusion: Comparison Between Subtotal Laminectomy and Total Laminectomy.
Seong Dae AN ; Tai Hyoung CHO ; Yun Kwan PARK ; Se Hoon KIM ; Jung Yul PARK ; Jung Keun SEO
Korean Journal of Spine 2010;7(3):150-154
OBJECTIVE: Whereas fusion with pedicle screw fixation has shown satisfactory clinical results, solid fusion has been reported to accelerate degenerative changes in adjacent unfused levels. The purpose of this study was to evaluate the effect of bone/ligament/bone integrity after subtotal or total laminectomies on the development of adjacent segment instability (ASI). The hypothesis that total laminectomy would increase ASI more than would subtotal laminectomy was analyzed. Material and METHODS: This is a retrospective study of 316 patients who were treated with posterior fusion and pedicle screw fixation between 1996 and 2001. After attempts to review all 316 patients and radiologic files, 36 patients who were diagnosed with ASI were carefully reviewed, including follow-up periods of 2-8 years. The medical records were carefully reviewed for recurrence of low back pain or neurologic symptoms after a period of postoperative relief, and the radiologic files were evaluated to determine instability. All patients had undergone single-level or multilevel instrumented posterior lumbar interbody fusion for intractable pain related to degenerative conditions of the spine. RESULTS: Patients over the age of 60 were at a higher risk of developing clinical ASI however,fusion length, level and gender were not associated with ASI. The ASI was noted to occur most commonly in the cranial segment prior to fusion. CONCLUSIONS: This study revealed more frequent ASI after total laminectomy than after subtotal laminectomy, especially in elderly patients. The ideal procedure will be one combining maximal canal and foraminal decompressions with minimal resection of bony structures and supporting ligaments.
Aged
;
Follow-Up Studies
;
Humans
;
Laminectomy
;
Ligaments
;
Low Back Pain
;
Medical Records
;
Neurologic Manifestations
;
Pain, Intractable
;
Recurrence
;
Retrospective Studies
;
Spine
8.Krukenberg Tumor Presenting with Brain Metastasis: A Case Report.
Taek Hyun KWON ; Tai Hyoung CHO ; Dong Jun LIM ; Jung Yul PARK ; Youn Kwan PARK ; Yong Gu CHUNG ; Hung Seob CHUNG ; Jung Keun SUH
Journal of Korean Neurosurgical Society 2000;29(9):1267-1270
No abstract available.
Brain*
;
Krukenberg Tumor*
;
Neoplasm Metastasis*
9.The Thoracic Radiculopathy in SAPHO Syndrome.
Seok HAN ; Tai Hyoung CHO ; Se Hoon KIM ; Dong Jun LIM ; Jung Yul PARK ; Yong Gu CHUNG ; Jung Keun SUH
Journal of Korean Neurosurgical Society 2001;30(11):1320-1323
SAPHO syndrome is an acronym for an increasingly recognized syndrome of synovitis, acne, pustulosis, hyperostosis, and osteitis. Most of the previously reported case are from Japan and Europe. The authors report a case of SAPHO syndrome in Korean female who presented with extrasternal neurologic symptoms. A 60-year-old female with thoracic and right chest wall pain presented with the sternocostoclavicular hyperostosis, and recurrent aseptic osteitis. Previously, she had hystrectomy and thyroidectomy due to uterine malignancy 25 years ago. Also, she started to take medications for palm and sole pustulosis 7 days prior to admission. Through evaluation of clinical, radiological, serological studies, studies was done along with bone needle biopsy for the biological reassessment. The hyperostosis was found in the pedicles of thoracic 8, 9, 10 vertebrae and sternoclavicular joint. Radio-isotope bone scan showed an accumulation of tracer in thoracic vertebra. The bone biopsy from these site showed increased osseous turnover, thickening of trabeculae accompanied by mild acculuation of granulation tissue and round cell infiltration, compatible with mild chronic inflammation with marrow fibrosis. The patient showed good response to conservative management. The authors report a case of SAPHO syndrome with thoracic radiculopathy. It is considered that SAPHO syndrome is related to spondyloarthropathy, and appears to have benign disease process with good prognosis.
Acne Vulgaris
;
Acquired Hyperostosis Syndrome*
;
Biopsy
;
Biopsy, Needle
;
Bone Marrow
;
Europe
;
Female
;
Fibrosis
;
Granulation Tissue
;
Humans
;
Hyperostosis
;
Hyperostosis, Sternocostoclavicular
;
Inflammation
;
Japan
;
Middle Aged
;
Neurologic Manifestations
;
Osteitis
;
Prognosis
;
Radiculopathy*
;
Spine
;
Spondylarthropathies
;
Sternoclavicular Joint
;
Synovitis
;
Thoracic Wall
;
Thyroidectomy
10.A Case of Neuroendocrine Carcinoma in Anterior Cranial Fossa.
Tai Hyoung CHO ; Jung Yul PARK ; Young Gu CHUNG ; Hung Seob CHUNG ; Yoon Kwan PARK ; Hoon Kap LEE
Journal of Korean Neurosurgical Society 1995;24(9):1084-1091
Neuroendocrine tumors are heterogeneous and potentially aggressive, and they must be distinguished from classic carcinoid tumors as the tumors share histologic features with their counterparts that occur in the lung, such as oat cell and intermediate cell carcinomas. Histopathologically, the oat cell neuroendocrine carcinoma displays itself in sheets, cord and rib-bons of small hyperchromatic, undifferentiated cells with very scanty cytoplasm. The intermediate cell is slightly larger than the oat cell and has more abundant cytoplasm. The authors report a case of a 52-year old patient with neuroendocrine carcinoma that occurred at the anterior cranial fossa extending into the nasal cavity. The patient presented with recurrent meningitis and seizure. Histological examination of the nasal biopsy tumor specimen confirmed neuroendocrine carcinoma, afterwhich the patient treated with a 4300 rad radiation therapy. Magnetic resonance imaging taken 2 years later showed an enlargement of the tumor mass at the anterior cranial fossa, and the patient was operated for removal of the intracranial tumor. The nasal cavity defect was reconstructed using rotation galeal flap technique.
Avena
;
Biopsy
;
Carcinoid Tumor
;
Carcinoma, Neuroendocrine*
;
Cranial Fossa, Anterior*
;
Cytoplasm
;
Humans
;
Lung
;
Magnetic Resonance Imaging
;
Meningitis
;
Middle Aged
;
Nasal Cavity
;
Neuroendocrine Tumors
;
Seizures