We measured serum levels of CA-125 and Tissue polypeptide antigen(TPA) in 135 patients with pelvic tumors(129 benign pelvic tumors and 6 malignant ovarian tumors) preoperatively. Each tumor marker was measured by immunoradiometric assay. Serum CA-125 levels of 35.0U/ml, 65.0U/ml and TPA levels of 80.0U/ml, 100.0U/ml were determined as cut-off values. The results were evaluated by each tumor marker and two tumor markers coincidently. The results were as follows : (continue)
Humans ; Immunoradiometric Assay ; Biomarkers, Tumor

BACKGROUND AND OBJECTIVES: Little is known about the treatment of open nasal bone fracture (ONF). The operative technique, timing, and management of ONF is still confusing. This study presents our treatment policy of ONF to help otolaryngologists decide proper management plan. MATERIALS AND METHODS: Of 380 consecutive patients who required surgical intervention, 57 patients underwent open nasal reduction. Of 57 patients, 15 had one-stage operation, and 42 had two- stage operation. Postoperative patients' satisfaction was evaluated using a visual analogue scale and the reasons of dissatisfaction were analyzed. RESULTS: ONF had poorer outcome than closed nasal bone fracture. Unsatisfactory cosmetic results such as scan of the external nose and change of the skin color were the most common problems associated with open nasal reduction. CONCLUSION: Operation timing and technique should be selectively applied to different types of nasal bone fracture and wound state. Meticulous wound care as well as accurate nasal bone reduction is mandatory for ONF.
Humans ; Nasal Bone* ; Nose ; Skin ; Wounds and Injuries

Hydramnios is a serious complication of pregnancy associated with a marked increase in perinatal mortality. A variety causes of this condition have been described, the majority of which relate to abnormalities of the fetus. Myotonic dystrophy is a progressive degenerative disease of the neuromuscular system, usually inherited in an autosomal dominant fashion. The disease is variable onset and clinical manifestations and usually severe in the male. Especially congenital myotonic dystrophy is a disease characterized by profound hypotonia. Affected infants present with varying degrees of respiratory failure, often necessitating immediate and prolonged ventilatory assistance. These neonates also have feeding difficulties due to impaired sucking and swallowing. The diagnosis of myotonic dystrophy in pregnancy is made retrospectively, following the birth of a severely affected neonates. A documented case of congenital myotonic dystrophy associated with hydramnios in two successive pregnancies is presented. The evidence suggests that myotonic dystrophy should be considered as a rare cause of recurrent hydramnios. We report a case of recurrent hyramnios in association with congenital myotonic dystrophy with a brief review of literatures.
Deglutition ; Diagnosis ; Fetus ; Humans ; Infant ; Infant, Newborn ; Male ; Muscle Hypotonia ; Myotonic Dystrophy* ; Parturition ; Perinatal Mortality ; Polyhydramnios* ; Pregnancy ; Respiratory Insufficiency ; Retrospective Studies