1.The Clinical Coures of Mild Neonatal Hydronephrosis.
Jong Ho PARK ; Young Tae LEE ; Jae Seop SHIN
Korean Journal of Urology 2000;41(7):872-877
No abstract available.
Hydronephrosis*
2.Two cases of nasopharyngeal carcinoma in children.
Tae Sun HA ; Chul Ho JANG ; Hee Young SHIN ; Hyo Seop AHN
Journal of the Korean Pediatric Society 1991;34(4):587-593
No abstract available.
Child*
;
Drug Therapy
;
Humans
;
Radiotherapy
3.A Case of Renal Cyst with Peripheral Thick Egg-shell Calcification.
Jae Seop SHIN ; Jae Woo KIM ; Young Tae LEE
Korean Journal of Urology 1989;30(2):235-238
Calcification is found in 4% to 12% of renal masses due to a number of causes and can be seen in various patterns. This is found in 1% to 3% of the simple renal cysts. Among these a peripheral egg-shell type of calcification is more rare. We experienced the simple renal cyst associated with the thick egg-shell calcification on the renal upper pole in a 66-year-old female complaining upper abdominal discomfort, so we report that with literature.
Aged
;
Female
;
Humans
4.A Metastatic Giant Cell Tumor of the Soft Tissue of the Thoracic Wall: A case report.
Duk Seop SHIN ; Tae Eun CHUNG ; Jang Hoon LEE ; Jun Hyuk CHOI
The Korean Journal of Thoracic and Cardiovascular Surgery 2007;40(7):526-528
A giant cell tumor of bone is a benign bone tumor, but has very high local recurrence rate and, very rarely metastasizes to the lung or a distant area. We report a case of a 29-year-old male patient presenting with a metastatic giant cell tumor of the soft tissue of the chest wall, who underwent a total resection of the radius for recurrence of the giant cell tumor. The tumor was not related to any bony structure of the thorax. We resected the tumor with a wide surgical margin. No evidence of malignancy was seen in the frozen and permanent pathological report.
Adult
;
Giant Cell Tumor of Bone
;
Giant Cell Tumors*
;
Giant Cells*
;
Humans
;
Lung
;
Male
;
Radius
;
Recurrence
;
Thoracic Wall*
;
Thorax
5.Herpes Zoster in Children with Malignancy.
Tae Heung KIM ; Kyung Chan PARK ; Jeong Aee KIM ; Seon Hoon KIM ; Yoo Shin LEE ; Hyo Seop AHN
Korean Journal of Dermatology 1990;28(4):441-444
We described the clinical manifestation of herpes zoster in thirteen children with underlying malignancies. Among the associated malignancies, hematologic malignancy including acute lymphotytic leukemia was the commonest and CNS tumors were also frequently associated. Pain was mild, and some showed high fever and abnormal liver function test results. Recurrent attacks were observed in 3 cases(23%). Thoracic segment and trigeminal nerve were commonly affected. In most cases, herpes zoster developed within two years after the diagnosis of the malignancy.
Child*
;
Diagnosis
;
Fever
;
Hematologic Neoplasms
;
Herpes Zoster*
;
Humans
;
Leukemia
;
Liver Function Tests
;
Trigeminal Nerve
6.Extracellular vesicles derived from small intestinal lamina propria reduce antigen-specific immune response
Tae-Seop SHIN ; Jae Yong PARK ; Yoon-Keun KIM ; Jae Gyu KIM
The Korean Journal of Internal Medicine 2022;37(1):85-95
Background/Aims:
Extracellular vesicles (EVs) are secreted from various types of cells and have specific functions related to their origin. EVs are observed in the small intestinal lamina propria (lpEVs), but their function remains unclear. This study aimed to investigate the role of lpEVs.
Methods:
LpEVs were isolated from antigen (ovalbumin [OVA])-fed mice (lpEVs/OVA), and administrated to the naïve mice for 5 days before induction of lung inflammation. Afterwards, the mice were sensitized and challenged with OVA to evaluate the role of lpEVs/OVA in the regulation of immune tolerance.
Results:
The isolated lpEVs/OVA were sphere-shaped, bi-layered vesicles of approximately 50 to 100 nm in size. The vesicles expressed CD81, A33 antigen, and major histocompatibility complex (MHC) class II on the surface. When administrated to naïve mice, the lpEVs/OVA migrated to the spleen. Intraperitoneal lpEVs/OVA administration to naïve mice decreased the immune response against sensitized antigen in a CD4+FoxP3+T cell-dependent manner.
Conclusions
EVs are actively secreted from small intestinal epithelial cells to deliver information about orally administered antigens to immune cells, which will facilitate the modulation of the immune response by acting as an intercellular communicasome.
7.Comparison of Microsurgical One-layer Vasovasostomy Techniques.
Je Won KIM ; Jae Seop SHIN ; Young Tae LEE
Korean Journal of Urology 2001;42(11):1185-1190
PURPOSE: The purpose of the study is to compare the outcomes between three different one-layer vasovasostomy techniques: original one-layer, modified one-layer, and V-V type one-layer microsurgical vasovasostomy. MATERIALS AND METHODS: We retrospectively reviewed the charts and surgical records of all surgical procedures performed on a series of 117 consecutive patients undergoing a microsurgical one-layer, modified one-layer or V-V type one-layer vasovasostomy between May 1995 and March 2000. An original one-layer vasovasostomy was used in 48 men (group 1), a modified one-layer vasovasostomy in 35 men (group 2), and V-V type one-layer vasovasostomy in 34 men (group 3). A successful outcome (patency) was defined as sperm presenting at the follow-ups. RESULTS: The sperm concentration (million/ml) and motility (%) were as follows: in original one-layer vasovasostomy 17.5 and 32.9, in modified one-layer vasovasostomy 26.1 and 28.5 and in V-V type vasovasostomy 30.5 and 32.3. There were no significant differences in patency (85.4%, 91.4% and 91.2%) and pregnancy rate (56%, 62.5% and 63.6%) of the procedures. If the obstructive interval had been less than 4 years, patency was 87.5% and pregnancy rate was 61.5%, 5 to 9 years 95.8% and 63.4% and 10 years or more 83% and 58.3%. There were no correlations between obstructive interval and rates of patency and pregnancy. CONCLUSIONS: The patency and pregnancy rate revealed slightly better result in modified one-layer or V-V type one-layer microsurgical vasovasostomy than in original one-layer microsurgical vasovasostomy. However, they had statistically no significant differences in overall.
Follow-Up Studies
;
Humans
;
Infertility, Male
;
Male
;
Pregnancy
;
Pregnancy Rate
;
Retrospective Studies
;
Spermatozoa
;
Vasectomy
;
Vasovasostomy*
8.Leiomyomas on the Bilateral Corpus Cavernosa of the Penis: A Case Report.
Sun Tae HWANG ; Chi Young PARK ; Sang Kuk YANG ; Jae Seop SHIN ; Hong Sup KIM ; Yong Soo LHO
Korean Journal of Urology 1995;36(5):584-586
Leiomyoma is a benign tumor, which usually occur at the smooth muscle of the gastrointestinal tract and uterus but rarely occurs on the corpus cavernosum of the penis. We experienced a patient with leiomyomas on the bilateral corpus cavernosa of the penis accompanied with impotence in a 60-year-old man. The patient was treated with complete local excision and has remained well without recurrence for l year, So we report this case with review of literatures.
Erectile Dysfunction
;
Gastrointestinal Tract
;
Humans
;
Leiomyoma*
;
Male
;
Middle Aged
;
Muscle, Smooth
;
Penis*
;
Recurrence
;
Uterus
9.Comparison of cardiopulmonary hemodynamic changes according to different ethanol bolus injection doses in piglets: the applicability of the study of ethanol injection effects on cardiopulmonary hemodynamic changes in sclerotherapy of congenital arterioven.
Byung Seop SHIN ; Byung Dal LEE ; Tae Soo HAHM ; Chung Su KIM
Korean Journal of Anesthesiology 2008;55(2):204-209
BACKGROUND: Ethanol injection during a sclerotherapy for the treatment of arteriovenous malformation, which performed under general anesthesia, can cause significant hemodynamic changes, even cardiovascular collapse. However, guideline for adequate management of hemodynamic change or preventing detrimental complication has still not been proposed. METHODS: Twenty-two piglets were randomly allocated to one of two groups: a 2.5 ml and a 4.0 ml ethanol. After baseline hemodynamic measurements, 2.5 ml or 4.0 ml of absolute ethanol was repeatedly administered in distal portion of renal vein with 10 minute intervals, and hemodynamic parameters were measured immediately before and after bolus injection of absolute ethanol until 10 minutes after final injection. RESULTS: Compared with 2.5 ml group, systolic, mean and diastolic pulmonary arterial pressures (PAP) and pulmonary vascular resistance (PVR) of 4.0 ml group showed significant differences from the first bolus injection of absolute ethanol. Hemodynamic parameters of 2.5 ml group did not show the increasing or decreasing tendency during a session, whereas, in 4.0 ml group, systolic, mean and diastolic PAP and PVR showed significantly increasing tendency. However, systemic arterial blood pressure, heart rate, central venous pressure, pulmonary capillary wedge pressure, cardiac output, and systemic vascular resistance did not show increasing or decreasing tendency in both groups. CONCLUSIONS: Based on the hemodynamic alterations observed from piglet model, the bolus injection of absolute ethanol during sclerotherapy in congenital arteriovenous malformation requires careful hemodynamic monitoring. We strongly recommend that anesthesiologist should carefully monitor the hemodynamic parameters after injection of relatively large amount of absolute ethanol.
Anesthesia, General
;
Arterial Pressure
;
Arteriovenous Malformations
;
Cardiac Output
;
Central Venous Pressure
;
Ethanol
;
Heart Rate
;
Hemodynamics
;
Organothiophosphorus Compounds
;
Pulmonary Wedge Pressure
;
Renal Veins
;
Sclerotherapy
;
Vascular Resistance
10.A Case of Reconstruction of Abdominal Wall Defect using Tensor Fascia Lata Myocutaneous Flap: The Defect Caused by a Wide Resection of Squamous Cell Carcinoma of Bladder Invading Abdominal Wall.
Young Tae LEE ; Young Kwon HONG ; Jong Ho PARK ; Je Won KIM ; Jae Seop SHIN
Korean Journal of Urology 1999;40(6):795-798
Squamous cell carcinoma of bladder is best treated with a radical cystectomy. Squamous cell carcinoma of bladder invading the abdominal wall is not commonly reported and hard to manage surgically. Abdominal wall defect caused by a wide resection of squamous cell carcinoma invading abdominal wall can be reconstructed using various muscle flaps. We performed a salvage cystectomy for a patient with squamous cell carcinoma of bladder invading abdominal wall up to skin, and the abdominal wall defect was successfully reconstructed using a unilateral tensor fascia lata myocutaneous flap.
Abdominal Wall*
;
Carcinoma, Squamous Cell*
;
Cystectomy
;
Fascia Lata*
;
Fascia*
;
Humans
;
Myocutaneous Flap*
;
Skin
;
Urinary Bladder*