1.A STUDY OF ION BEAM ASSISTED DEPOSITION(IBAD) OF TiN ON Ni-Cr Be ALLOY FOR SURFACE CHARACTERISTIC.
Soo Young CHOI ; Sun Hyung LEE ; Ik Tae CHANG ; Jae Ho YANG ; Hun Young CHUNG
The Journal of Korean Academy of Prosthodontics 1999;37(2):212-234
Dental restorative materials must have the physical properties to withstand wear and corrosion. Base metal alloys possess better mechanical properties and lower price than the gold alloys. For these reason such alloys have largely replaced the precious metal alloys. One aspect to consider is the release of metal substances to oral environment. The release of elements from dental alloys is a continuing concern because the elements may have the potentially harmful biological effects on local tissue. The purpose of this study was to minimize metal release on the nonprecious metal surfaces by ion bea assisted deposition(IBAD) of titanium nitride (TiN). Ni-Cr-Be alloys with and without TiN coatings were secured in an wear test machine opposing ruby ball to determine their relative resistance to wear with 100m, 200m, 300m and 400m sliding distance. And the corrosion behavior of the Ni-Cr-Be alloys with and without TiN coating and 3 dental noble alloys have been studied. Potentiodynamic curves were used to analyse the corrosion characteristics of the alloys. The measurement of the released Ni and Ci ions was conducted by analysis of the electrolyte solution with atomic absorption spectroscopy. The results were as follows : 1. The critical sliding distance that wore down TiN coating of 2.5micrometer thickness in this study condition was 300m. 2. Ion beam assisted deposition of TiN showed a good surface modification with respect to the properties of wear and corrosion resistance. 3. X-ray diffraction showed that the strongest peak of TiN(111) in the coatings. 4. The release of Ni and Cr ions from alloys measured by means of atomic absorption spectroscopy was reduced by ion beam assisted deposition of TiN.
Absorption
;
Alloys*
;
Corrosion
;
Dental Alloys
;
Gold Alloys
;
Ions
;
Spectrum Analysis
;
Tin*
;
Titanium
;
X-Ray Diffraction
2.Antigenicity of the G2 Glycoprotein in Cell - Mediated Immune Response Against Hantanvirus Infection.
Ik Sang KIM ; Myung Sik CHOI ; Myung Ju YI ; Tae Hee HAN
Journal of the Korean Society for Microbiology 1998;33(6):619-624
Hemorrhagic fever with renal syndrom is an acute febrile disease which is caused by Hantanvirus and several other viruses that belong to the genus Hantavirus. Gl and G2 glycoproteins of Hantanvirus have been thought to be involved in protective immunity against Hantanvirus infection. In this study, the antigenicity of G1 and G2 glycoproteins in cell mediated immune response was investigated. When peripheral blood mononuclear cell fraction from recovered hemorrhagic fever with renal syndrome patient was cultivated with a recombinant protein containing amino-terminal 78 amino acids of G2 glycoprotein, these cells were activated to proliferate and secreted significant amount of interleukin-2 and interferon-r. These results suggest that T cell epitope exists in the amino-terminal region of G2 glycoprotein.
Amino Acids
;
Epitopes, T-Lymphocyte
;
Fever
;
Glycoproteins*
;
Hantavirus
;
Hemorrhagic Fever with Renal Syndrome
;
Humans
;
Interleukin-2
3.Xanthogranulomatous oophoritis: a case report.
Ik YANG ; Young Tae KO ; Dong Ho LEE ; Jae Hoon LIM ; Woo Suk CHOI
Journal of the Korean Radiological Society 1992;28(1):146-148
A case of xanthogranulomatous oophoritis is presented in a patient who had a 3-month history of intrapelvic mass protruding into the vagina. The sonographic findings are a well defined mass shadowing lower echogenicity than the echo of the uterus at the posteosuperior aspect of the uterus. The CT findings are an enhancing solid mass with central necrosis containing a multiseptated cystic component.
Female
;
Humans
;
Necrosis
;
Oophoritis*
;
Shadowing (Histology)
;
Ultrasonography
;
Uterus
;
Vagina
4.Two Cases of Fetal Bilateral Renal Agenesis.
Jong Kuk BAEK ; Jung Hwan HYUN ; Yun Seok CHOI ; Tae Sang KIM ; Ik Su KIM
Korean Journal of Obstetrics and Gynecology 1999;42(9):2122-2125
Fetal bilateral renal agenesis is a lethal congenital anomaly. An early and reliable prenatal diagnosis is extremely important as it may offer options for pregnancy termination as early as possible. The criteria for the ultrasonographic diagnosis of bilateral renal agenesis are severe oligohydramnios, nonvisualization of the bladder, and the empty renal fossa. However, severe oligohydramnios makes it difficult to diagnose the disease because of poor sonographic resolution. We present two cases of bilateral renal agenesis, one is diagnosed by ultrasonography after amnioinfusion at 24 weeks gestation, the other is diagnosed postnatally after term delivery.
Diagnosis
;
Female
;
Oligohydramnios
;
Pregnancy
;
Prenatal Diagnosis
;
Ultrasonography
;
Urinary Bladder
5.Correlation between Chromosome Abnormalities and Genomic Imprinting in Developing Human 2) Independent Expression of Imprinted Genes, H19 and Insulin-like growth factor II (IGF2), in Androgenetic Hydatidiform Moles.
Sung Ik CHANG ; Bo Hwa CHOI ; Tae Sung LEE ; Dae Kwang KIM ; In Hwan LEE
Korean Journal of Anatomy 1998;31(4):611-617
Human uniparental gestations such as androgenetic hydatidiform moles provide a model to evaluate the integrity of parent-specific gene expression,-i.e, genomic imprinting,- in the absence of a complementary parental genetic contribution. Several imprinted genes are characterized so far including the insulin-like growth factor-2 gene (IGF2) coding for a fetal growth factor and the Hl9 gene whose normal function is unknown but which is likely to act as an untranslated mRNA for its tumor-suppressing function. IGF2 is expressed exclusively from the paternal allele while Hl9 from the maternal allele. Such an alternate expression is quite interesting because both Hl9 and IGF2 genes are located close to each other on chromosome 11p15.5. An in situ hybridization analysis has shown strong expression of Hl9 and IGF2 alleles in nine hydatidiform moles. Especially, a prominent expression of Hl9 and IGF2 was detected in cytotrophoblast and the cellular localization was almost paralleled in Hl9 and IGF2 transcripts . Hl9 and IGF2 genes could be expressed either biallelically or monoallelically in the moles. However, IGF2 biallelic expression did not affect allele-specificity of Hl9 expression.. These results suggest that both H19 and IGF2 transcripts are expressed in the same cells and that the functional imprinting of H19 and IGF2 genes in hydatidiform moles can be controlled individually and independently of each other.
Alleles
;
Chromosome Aberrations*
;
Clinical Coding
;
Female
;
Fetal Development
;
Genomic Imprinting*
;
Humans*
;
Hydatidiform Mole*
;
In Situ Hybridization
;
Insulin-Like Growth Factor II*
;
Parents
;
Pregnancy
;
RNA, Messenger
;
Trophoblasts
6.A Clinical Alnalysis of Arthorodesis of the Knee Joint
Young Tae KANG ; Taik Seon KIM ; Young Jong CHOI ; Jae Ik SHIM ; Dong Eun KIM
The Journal of the Korean Orthopaedic Association 1986;21(5):844-854
In the past, arthrodesjs was a widely used procedure but in recent times, with the development of replacement arthroplasty, decreased in tuberculosis and polio. etc, it is not commonly used by orthopedic surgeons. However, for those in the young age group, people employed in hard labor and patients with acute inflammatory disease, arthrodesis is through to be more appropriate than replacement arthroplasty. From January 1980 to December 1985, 20 cases of arthrodesis of the knee joint were carried out. The results were follows.; 1. Methods of arthrodesis used were Charnley compression arthrodesis in 10 cases, Hoffman compression arthrodesis in 2 cases, cross pinning in 3 cases and and cross pinning with patella graft in 5 cases. 2. Bone union was seen in all 12 cases of compression arthrodesis at an average of 21.3 weeks while bone union was seen in 7 out of 8 cases of non-compression arthrodesis at an average 25 weeks. 3. Among the 20 cases, complication were pseudoarthrthrosis in one case, pin tract infection in 2 cases and skin necrosis in 5 cases. 4. Inconclusion of the above results, bone union was carried out in 19 cases out of total 20 cases, and compression arthrodesis showed faster bone union at an average of 3.7 weeks earlier than non-compression arthrodesis.
Arthrodesis
;
Arthroplasty, Replacement
;
Humans
;
Knee Joint
;
Knee
;
Necrosis
;
Orthopedics
;
Patella
;
Poliomyelitis
;
Skin
;
Surgeons
;
Transplants
;
Tuberculosis
7.Coronary Intervention of Cardiogenic Shock in Acute Myocardial Infarction.
Jae Woong CHOI ; Chang Sup SONG ; Chin Woo IMM ; Tae Hoon AHN ; In Seog CHOI ; Ik Kyun SHIN ; Young Hoon PARK
Korean Circulation Journal 1996;26(2):449-454
BACKGROUND: Despite improvement of mortality in acute myocardial infarcrtion, high mortality rate associated with cardiogenic shock remains essentially unchanged. We have reviewed our result of coronary intervention in 15 patients and found relative survival advantage. METHODS: Between Sep. 1992 and Aug. 1995, 15 consecutive patients(M. 10, F. 5) with cardiogenic shock in acute myocardial infarction were treated with coronary intervention using ballon PTCA. IABP was inserted in all patients prior to PTCA. RESULTS: 1) Most commonly found infarct related artery was left anterior descending artery(11) followed by right coronary artery(3) and left main coronary artery(1). 2) Successful reperfusion rate was 86.7%(13/15), and in-hospital mortality rate was 26.7%(4/15). 3) In-hospital mortality was higher in elderly patients compared with less than 70yaer old patients(0%(0/11)vs. 75.0%(3/4)(P < 0.05). 4) Mortality rate was lower in single vessel disease than multivessel disease(11.1%(1/9) vs. 50%(3/6) p<0.05). CONCLUSION: Although this study is uncontrolled, the date suggest that urgent coronary intervention for improving coronary perfusion may reduce mortality of acute myocardial infarction complicated by cardiogenic shock, particularly with single vessel disease and young age group.
Aged
;
Arteries
;
Hospital Mortality
;
Humans
;
Mortality
;
Myocardial Infarction*
;
Perfusion
;
Reperfusion
;
Shock, Cardiogenic*
8.A case report of cerebral sparganosis associated with seizure.
Kyung Sik KOH ; Tae Yul CHOI ; Ik YANG ; Woo Suk CHOI ; Sun Yung SHIN ; Hwan Jo SUH
Korean Journal of Infectious Diseases 1993;25(4):393-398
No abstract available.
Seizures*
;
Sparganosis*
9.Role of IGF2 Gene in Developing Human Ovary.
Hyung Tae PARK ; Hong Tae KIM ; Bo Hwa CHOI ; Jung Ran KIM ; Daeg Kwang KIM ; In Jang CHOI ; In Hwan LEE ; Sung Ik CHANG
Korean Journal of Physical Anthropology 1996;9(2):141-147
To understand the role of IGF2 gene in development of human ovary, IGF2 expression was detected by monoclonal antibody for IGF2 to its producted protein with immunohistochemical technique on human ovarian tissues. The results was as follows. IGF2 was highly expressed in ovum of mature follicle, IGF2 expression, however, was not high in granulosa and the cells. IGF2 was not highly expressed in ovum of primary follicle. Highly expressed IGF2 was found on corpus luteum and no expression of IGF2 was found in stroma and epithelial cells. These results suggest that IGF2 is important role in ovulation and in production of progesterone. Abnormal IGF2 expression may be concerned to carcinogenesis of ovarian tumor because most of all tumor from ovary is originated from epithelium.
Carcinogenesis
;
Corpus Luteum
;
Epithelial Cells
;
Epithelium
;
Female
;
Humans*
;
Ovary*
;
Ovulation
;
Ovum
;
Progesterone
;
Theca Cells
10.The prognostic significance of steroid hormone receptors, bcl-2 and p53 mutation in correlation with clinicopathological prognostic factors in endometrial cancer.
Sang Woon KIM ; Jae Wook KIM ; Eun Gyung CHOI ; Young Tae KIM ; Nam Hoon JO ; Woo Ik YANG
Korean Journal of Obstetrics and Gynecology 2000;43(12):2127-2134
No abstract available.
Endometrial Neoplasms*
;
Female