No abstract available.
Chiroptera*

The changes in the size of human oviduct and ovary after immersion in formalin (4%, 10%) were investigated. The results were as follows : 1. After fixation, the length of oviduct was significantly reduced to 93%, but the cross sectional area of oviduct was significantly increased. The length of oviduct showed no significant difference between 4% and 10% formalin. The length of ovarian ligament was also significantly reduced to 84% after fixation. 2. After fixation, the volume of oviduct was increased significantly and showed a difference between the two fixatives. The volume of oviduct in 4% formalin has increased to 107%, as compared to 103% increase in 10% formalin. 3. After fixation, the volume of ovary was increased significantly and showed a difference between the two fixatives. The volume of ovary in 4% formalin has increased to 109%, as compared to 103% increase in 10% formalin.
Animals ; Female ; Fixatives ; Formaldehyde* ; Humans* ; Immersion* ; Ligaments ; Ovary* ; Oviducts*

No abstract available.
Cardiac Catheterization* ; Cardiac Catheters* ; Echocardiography* ; Pulmonary Valve Stenosis*

Background: Fluvastatin is the first entirely synthetic 3-hydroxy-3-methylglutaryl-coenzyme A(HMG-CoA) reductase inhibitor. Clinical data indicate that this agent exhibits the proven efficacy of its class and also has some theoretical advantages in safety for long-term use because of its unique pharmacololgic property consistent with hepatoselectivity(i.e., low systemic exposure). This study is to evaluate efficacy and safety of fluvastatin in hypercholesterolemic patients in Korea. Methods: An open clinical trial with fluvastatin was conducted in 31 subjects who continued to have high blood cholesterol levels of 6.21 mmol/L(240 mg/dl) or greater after 1 month of lipid-lowering diet plus single blind placebo period. Fluvastatin was administered for 8 weeks with the initial dose of 20 mg per day and if serum cholesterol levels did not fall below 5.20 mmol/L(200 mg/dl) after 4 weeks the dose was increased to 40 mg per day for the second 4 weeks. On each visit every 4 weeks they underwent interview and laboratory tests about side effects and tolerability. Results: The mean % changes in plasma total cholesterol and LDL-cholesterol from baseline were
Cholesterol ; Creatine Kinase ; Diet ; Humans ; Hypercholesterolemia ; Korea ; Oxidoreductases ; Plasma ; Sleep Stages ; Triglycerides

No abstract available.
Granuloma, Lethal Midline*

No abstract available.
Gastrostomy*

BACKGROUND: The self-inflating bag-valve resuscitator is an useful breathing support equipment in the cardiopulmonary resuscitation, the transportation of patients who required ventilation assist, or respiratory therapy. The inspiratory oxygen concentration (FiO2) or tidal volume (VT) delivered to the patient depends on various conditions during bag-valve ventilation. METHODS: During bag-valve ventilation without a reservoir at oxygen flow rates of 10 l/min, we evaluated fifty six volunteers to determine the FiO2 and VT at ventilatory frequencies of 10, 12 and 15 cycles per minute and to observe the effect of hand size and grasp power on FiO2 and VT in two-hand compression methods. RESULT: The FiO2 at frequency of 10 cycles/min were 50.1% and it was higher than other ventilatory frequencies. However, the VT was not statistically different among the changes of ventilatory frequency. In the change of VT according to characteristics of the hand, the operator's hand size exerted influence on VT(larger vs. smaller ; 942ml vs. 885ml, p<0.05), but the grasp power of the hand did not significantly affect. Separate analyses with size or grasp power of the hand failed to reveal significant differences of the FiO2. CONCLUSION: The results suggest that a slowing of ventilatory frequency within the allowable ranges for adequate gas exchange increase the FiO2 during bag-valve ventilation without reservoir, and that hand size may exert influence on the VT without FiO2 changes but grasp power may not be a contributing factor to the VT or FiO2 changes.
Cardiopulmonary Resuscitation ; Hand Strength ; Hand* ; Humans ; Oxygen* ; Respiration ; Respiratory Therapy ; Tidal Volume* ; Transportation of Patients ; Ventilation* ; Volunteers

A Statistical observations were done on 587 pediatric patients who were diagnosed as having congenital heart disease by cardiac catheterization angiography and operation at Dong San Hospital Keimyung University, during the period of January 1982 to june 1987. The results were as follows 1) Out of 587 patients, 317 cases were male and 276 cases were female. There were female preponderance in atrial septal defect and patent ductus arteriosus, whille in male tetralogy of Fallot, pulmonary stenosis, and ventricular septal defect. 2) The incidence of congenital heart disease were as folliws;ventricular septal defect 35.7% tetralogy of Fallot 17.5%, patient ductus arteriousus 13.9%, arterial septal defect 7.5% and pulmonary stenosis 2.9%. 3) Most of the patients were visited hospital for the first time between the age of 2 and 10 years. 4) Assosiated anomalies of major congenital heart disease were as follows:the most commonly associated anomaly in ventricular septal defect were pulmonary stenosis and patent ductus arteriosus. Pulmonary stenosis was frequently associated with atrial septal defect. Right sided aortic arch and pentalogy were assosiated with tetralogy of Fallot. The mitral regurgitation was associated with patent ductus arteriosus mostly. 5) The overall surgical mortality was 6.8%. The mortality was high in tetralogy of Fallot(16.1%), transposition of great vessels(28.5%).
Angiography ; Aorta, Thoracic ; Cardiac Catheterization ; Cardiac Catheters ; Ductus Arteriosus, Patent ; Female ; Heart Defects, Congenital* ; Heart Septal Defects, Atrial ; Heart Septal Defects, Ventricular ; Humans ; Incidence ; Male ; Mitral Valve Insufficiency ; Mortality ; Pulmonary Valve Stenosis ; Statistics as Topic* ; Tetralogy of Fallot

PURPOSE: To evaluate CT findings of internal hernia. MATERIALS AND METHODS: Three patients with internal hernia had abdominal CT scans and two of them had small bowel follow through examinations. The CT features of two patients with retroanastomotic and one patient with left paraduodenal hernia were evaluated and correlated with small bowel follow through examinations, and surgical findings. Two patients with retroanastomotic hernia had a history of subtotal gastrectomy with antecolic gastrojejunostomy. The diagnosis of internal hernia was made on the basis of surgical find ings in two patients of retroanastomotic hernia, and characteristic barium study findings in one patient of left paraduodenal hernia. RESULTS: The small bowel follow through examination showed small bowel loops gathered in a circumscribed mass in the left mid abdomen, and delay in passage through these loops. In case of left paraduodenal hernia, abrupt narrowing of the distal duodenum could be identified. The characteristic CT findings of all three patients were whorling of the mesentery and mesenteric vessels in the left mid-abdomen. In the patient with left paraduodenal hernia, after resolution of the gastrointestinal symptoms, a follow-up CT scan showed spontaneous disappearance of whorling of the mesentery and mesenteric vessels suggesting spontaneous resolution of the hernia. In the other two cases, upon exploration of the abdomen, dilatation of afferent duodenum caused by adhesion between ligament of Treitz and adjacent bowel walls, and retro- anastomotic herniation of the efferent loops were found. CONCLUSION: The usual diagnosis of internal hernia is based on the appearance of the small bowel follow through examination. However, we consider that the whorling appearance(we call it whorling sign) of the mesentery and mesenteric vessels on CT scan is also suggestive of internal hernia in patients under clinical suspicion.
Abdomen ; Barium ; Diagnosis ; Dilatation ; Duodenum ; Follow-Up Studies ; Gastrectomy ; Gastric Bypass ; Hernia ; Humans ; Ligaments ; Mesentery* ; Tomography, X-Ray Computed

Postoperative hemorrhage after eardiopulmonary bypass(CPB) is one of the major causes of morbidity and mortality. Approximately 3% of patients have undergone surgical reexploration after open heart surgery. Coagulopathies after CPB are due to multiple hemostatic defects caused by hemodilution of procoagulants, firbrinogen, platelet, drugs and mechanical destruction by CPB machine. Thromboelastography(TEG) is the measures of viscoelastic properties of blood coagulation by providing information on the interaction of all the coagulation precursors and gives more clinically useful information on coagulation than that available from routine coagulation tests (RCT) or activated coagulation time(ACT). TEG is simple to use and can be performed within 30 minutes of blood sampling. Thirty-five patients of open heart surgery(12 were cyanotic and 23 were noncyanotic patients) were studied for the coagulation with TEG, ACT and RCT before and after CPB. Reaction time(R time), Coagulation time(R+K time), Maximum amplitude(MA), A60(Amplitude 60 min after MA), A60/MA index(Whole blood clot lysis index) and alpha angle were mea- sured in TEG, and at the same time RCT and ACT were also measured. Statistical analysis were performed by Student-t test for, significance, and 6 of TEG and 5 of RCT measurements were evaluated by multiple regression analytic methods(stepwise methods) for the correlation. The results were as follows: 1) TEG measurements before CPB were R time; 9.5+/-2.0min., R+K time; 14.6+/-2.7 min., MA; 52.4+/-3.6mm., A60; 45.1+/-4.5mm, Alpha; 46.2+/-5.50 and after CPB R time, 12.3+/-3.6min., R+K time, 24.3+/-16.4min., MA; 41.7+/-5.8min, A60; 36.4+/-4.4mm, Alpha, 32.0+/-8.90, respectively. There were significant differences between the measurements before and after CPB(P<0.005). 2) Before and after CPB, There was no significant difference between cyanotic and noncyanotic group in TEG 3) There was no fibrinolysis after CPB on TEG 4) There was significant correlation at the level of 95% significance after CPB following as; (1) R time vs aPTT and fivrinogen (2) R+K time vs PT, platelet and fibrinogen (3) MA vs platelet and PT (4) A60 vs platelet and fibrinogen (5) Alpha angle vs PT, aPTT, fibrinogen and Platelet 5) As the result of Multiple Regression Analytic Methods, R+K time, MA and Alpha angles after CPB could predict aPTT of RCT at the level of 99.5% signficance, In summary, thromboelastography is simple and easy to use in operating room for the diagnosis of coagulopathies compared with RCT.
Blood Coagulation ; Blood Platelets ; Cardiopulmonary Bypass* ; Diagnosis ; Fibrinogen ; Fibrinolysis ; Heart ; Hemodilution ; Hemostasis* ; Humans ; Mortality ; Operating Rooms ; Postoperative Hemorrhage ; Thoracic Surgery ; Thrombelastography*