No abstract available.
Adolescent ; Emphysema/etiology* ; Face ; Human ; Male ; Mediastinal Emphysema/etiology ; Neck ; Peptic Ulcer Perforation/complications* ; Pneumoperitoneum/etiology ; Stomach Ulcer/complications*

The occurrence of malignancies during pregnancy has increased over the last decades. Risks of cancer surgery during pregnancy include spontaneous abortion and preterm labor. Radiation therapy especially during the first trimester generally is not offered because it poses high risks : teratogenecity, induction of childhood malignancies and hematologocal disorders. All chemotherapeutic agents used in the treatment of breast cancer are pregnancy category D, meaning that teratogenic effects have occurred in humans. We report a baby of a 33-year-old pregnant woman with breast cancer. She was treated with modified radical mastectomy one month before the pregnancy and full-dose adriamycin, cyclophosphamide and taxol since the first trimester, and 5,400 cGy of radiation therapy in the second trimester. The infant was delivered at 33+6 weeks of gestation and showed no evidence of malformation or abnormalities and developed normally until 8 months of corrected age.
Abortion, Spontaneous ; Adult ; Breast Neoplasms* ; Breast* ; Cyclophosphamide ; Doxorubicin ; Drug Therapy* ; Female ; Humans ; Infant ; Mastectomy, Modified Radical ; Obstetric Labor, Premature ; Paclitaxel ; Pregnancy ; Pregnancy Trimester, First ; Pregnancy Trimester, Second ; Pregnant Women*

OBJECTIVES: Recently, the number of female gamblers has increased, therefore, the proportion of women is around one third of all the pathological gamblers. However, the majority of previous studies on pathological gambling have been performed with only male subjects and tended to generalize those results to females. The authors have investigated the gender differences in level 3 gambling in terms of characteristics of gambling and associated psychiatric symptoms. METHODS: 166 participants (104 males, 62 females) who came to a casino have been evaluated for their sociodemographic data and the characteristics of gambling. Participants completed the following self-reported questionnaires: The Korean Version of South Oaks Gambling Screen (KSOGS), The Korean Version of Zung Self-Rating Depression Scale (SDS), The Korean Version of Beck Anxiety Scale (BAI), The Korean Version of Barratt Impulsiveness Scale (BIS), The Korean Version of Behavioral Activation/Inhibition System Scale (K-BAS/BIS), CAGE (The CAGE Questionnare), The Korean Version of Eating Attitudes Test (KEAT). RESULTS: Female level 3 gamblers had significantly later age of onset for their gambling behavior than male. Female level 3 gamblers were significantly more depressed and male level 3 gamblers had more severe alcohol use problems. The proportion of the participants with more severe eating problems was significantly higher in female level 3 gamblers than their male counterparts. CONCLUSION: This study suggests the importance of considering the associated depressive symptoms and eating problems in female gamblers.
Age of Onset ; Anxiety ; Depression ; Eating ; Female* ; Gambling ; Humans ; Male ; Surveys and Questionnaires

No abstract available.
Antibodies, Monoclonal* ; Humans* ; Interleukins*

We presented here a rare case of intestinal Behecet's disease simulating Grohn's disease. A 20 year old female complained of recurrence of oral ulcer, genital ulcer, arthralgia, erythema nodosum, abdominal pain and diarrhea, but she had no anal ulcer or anal fistulas. The colonoscopic examanation disclosed diffuse colonie involvement with multiple longitudinal ulcers and inflammatory pseudopolyposis. In hospital, she received ileocecectomy because of distal ilea perforation. Postoperative specimen showed multiple geographic ulcer on ileocecal region, creeping mesenteric fat and thickening of cecal wall. Pathological examination showed perivasculitis, transmural inflammation, fissuring, multiple lymph follicles which are compatible with intestinal Behect's disease. There were no granuloma sugges tive of Crohn's disease. Clinically, the patient met the international criteria of Behcet's disease. Punched out ulcer in the ileocecal region and pathological findings described above confirmed the diagnosis of intestinal Behcet's disease.
Abdominal Pain ; Arthralgia ; Colon* ; Crohn Disease ; Diagnosis ; Diarrhea ; Erythema Nodosum ; Female ; Fissure in Ano ; Granuloma ; Humans ; Inflammation ; Oral Ulcer ; Rectal Fistula ; Recurrence ; Ulcer* ; Young Adult

The occurrence of the small intestinal adenocarcinoma is infrequent and the primary adenocarcinoma of the jejunum is rare. The survival of adenocarcinoma of the small bowel does not improve over the past three decades. Although symptoms appeared to be of long duration, most patients were diagnosed with advanced disease. All reports agree that these tumors are difficult to achieve good examination of the small bowel by both clinician and radiologist, so it cause a significant delay in diagnosis. The survival of these tumors appear to correlate with stage at presentation, and therefore early and aggressive diagnostic intervention seems to improve the outlook. We report a case of primary jejunal adenocarcinoma assoeiated with iron deficiency anemia with literatures review.
Adenocarcinoma* ; Anemia, Iron-Deficiency ; Diagnosis ; Humans ; Jejunum

No abstract available.
Humans

Spontaneous renal rupture with subcapsular renal hematoma is a rare disease entity. Hereby, we report a 60-year-old female who presented with abrupt right flank pain and was diagnosed as spontaneous renal rupture with subcapsular hematoma related to urinary tract infection and review related literatures.
Female ; Flank Pain ; Hematoma ; Humans ; Kidney ; Middle Aged ; Rare Diseases ; Rupture* ; Rupture, Spontaneous ; Urinary Tract Infections*

Most patients with tyrosine kinase inhibitor (TKI)-sensitive non-small cell lung cancer (NSCLC) eventually develop acquired resistance to TKIs. Factors that affect TKI-sensitive patient survival after progression during TKI treatment remain unknown. We attempted to identify factors that affected post-progression survival. We retrospectively reviewed 81 advanced NSCLC patients with disease progression following tumor response and durable (> or = 6 months) disease stabilization with first-line or second-line gefitinib. Post-progression survival (PPS) and characteristics were investigated and compared in patients who did (n = 16) and did not (n = 65) resume TKIs. Most patients were female never-smokers with adenocarcinoma. Median overall PPS was 10.3 months (95% confidence interval [CI], 7.458-13.142). Age, gender, smoking history, histology, Eastern Cooperative Oncology Group performance status at gefitinib initiation, initial stage, and platinum-based chemotherapy after gefitinib were not significant predictors of PPS. Pemetrexed use after gefitinib significantly improved PPS (18.5 vs 8.6 months; hazard ratio [HR], 0.45; P = 0.008). Gefitinib reuse tended to lengthen PPS but was insignificant in multivariate analysis (27.4 vs 8.8 months; HR, 0.53; P = 0.095). NSCLC patients assumed to have clinically acquired resistance to TKIs had relatively long PPS. TKIs reuse or pemetrexed use after progression with gefitinib may improve PPS.
Adenocarcinoma/drug therapy/*mortality ; Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/therapeutic use ; Carcinoma, Non-Small-Cell Lung/drug therapy/*mortality ; Disease-Free Survival ; Drug Resistance, Neoplasm ; Female ; Glutamates/*therapeutic use ; Guanine/*analogs & derivatives/therapeutic use ; Humans ; Lung Neoplasms/drug therapy/*mortality ; Male ; Middle Aged ; Protein Kinase Inhibitors/*therapeutic use ; Quinazolines/*therapeutic use ; Retrospective Studies ; Survival ; Treatment Outcome

No abstract available.
Retina* ; Uveitis*