No abstract available.
Delivery of Health Care* ; Humans ; Japan*

No abstract available.
Behavioral Medicine*

The 10 cases of psoriasis were treated with topical application of 0.3% of Vitamin A acid ointment, once daily, without dressing, and were observed at weekly intervals. Histopathological studies were obtained 5 cases out of former 10 psoriasis patients, before and 3 weeks after treatment. Clinical results(table 1)revealed 6 cases of good result, 4 cases of moderate resuIt in efficacy. In generally, the scales and infiltration were more rapidly responded to the treatment than the erythemas. Histopathological findings after treatment (table 2) were revealed, compare with before treatment, reduced or absence of parakeratosis, regenration of granular cell layer, reduced acanthosis, and decreased inflammatory cell infiltration in the upper derms. Side reaetions, as irritation dermatitis, occurred only on the normaI skin especially periollicular regions, which was cured easily by wet dressing with Burow's solution for a few days. Recurrences were occurred in 3 cases of the treated 10 patients, within 10 days after stop of the therapy.
Bandages ; Dermatitis ; Erythema ; Humans ; Parakeratosis ; Psoriasis* ; Recurrence ; Skin ; Tretinoin* ; Vitamin A* ; Vitamins* ; Weights and Measures

No abstract available.
Fatty Liver* ; Obesity*

Malignant hibernoma, also called round cell liposarcoma, is a subtype of liposarcome. It is composed of so-called mulberry cells with scanty stroma. The characteristic mulberry cell has a centrally located nucleus and multivaculoated foamy cytoplasm in which eosinophilic fat droplet granules are contained. The authors experienced a case of malignant hibernoma. The patient, 16-year-old male, had a slowly growing nontender firm solitary subcutaneous mass on the center of chin for about 6 months. He hadn't episode of trauma or exposure to X-ray irradiation on the chin. Histopathological findings of punch biopsied skin specimen revealed compact mulberry cells intermingled with normally matured fat cells in the deep dermis and muscle layer, but there were neither significant infiltrations of lymphocyte nor myxoid changes. The tumor mass was totally removed including surrounding tissues as much as possible. The surgically removed tissue specimen revealed brownish discoloration in the center. Histopathologically, it revealed numerous capillaries and massive extravasated erythrocytes like a hemangiona, just beneath the hibernoma mass. There was no evidence of local recurrence or metastasis during 2.5 years of post-operative observation.
Adipocytes ; Adolescent ; Capillaries ; Chin ; Cytoplasm ; Dermis ; Eosinophils ; Erythrocytes ; Humans ; Lipoma* ; Liposarcoma ; Lymphocytes ; Male ; Morus ; Neoplasm Metastasis ; Recurrence ; Skin

Normal albino rats weighing 180-200 gm were used for a series of this investigation on change of skin mast cell under general and local anesthesia. At first, left side abdominal skin was prepared by hair cutting with scissors about 3cm square and eight irritations by mean of biting with tip of forceps mosquito were applied along the prepared skin margin. Skin specimens were submitted from central area which surrounded by irritated points and also from intact contra-lateral area in 15, 30, 60 and l20 minutes invervals. Submiitted skin specimens were fixed in 10% formalin solution, then were stained with 1% toluidine blue. The number of mast cell was counted under 450X of microscopic examination. CONCLUSION l. There were two stages in changes of skin tissue mast cell number on normal saline solution injected area and irritated area by mean of biting with tip of forceps without any types of anesthesia. i) Decreasing stage: Number of skin tissue mast cell was decreascd and reached to the lowest level at 30 minutes after each irritation. ii) Increasing stage: Number of skin tissue mast cell was increased to the highest level at 120 minutes after each irritation. 2. General ether anesthesia could not infIuence on the change of mast cell number after mechanical biting irritation. 3, Local anesthesia with 2% procaine hydrochloride solution revealed slightly suppressing effect to increasing number of mast cell at 60 and 120 minutes after mechanical irritation. Hnwever, it was not evidence at 15 and 30 minutes after mechanical irritation. 4. There was no significant change of rnast cell number in the intact contralateraI skin area within 120 minutes under gencral and local anesthesia. 5. The number of degranulated mast cells did not correlated with counted total number of mast cells.
Anesthesia ; Anesthesia, Local ; Animals ; Cell Count ; Culicidae ; Ether ; Formaldehyde ; Hair ; Mast Cells* ; Procaine ; Rats ; Skin ; Sodium Chloride ; Surgical Instruments ; Tolonium Chloride

No abstract available.
Arthritis, Rheumatoid*

No abstract available.
Arthritis, Rheumatoid*

No abstract available.
Mast Cells* ; Skin Diseases*

A case of lupus miliaris desseminatus faciei, 23 year old male was reported. The multiple minute discrete yellowish brown superficial nodules, 2 to 3 mm in diameter, revealed apple-jelly color under diascopy without any subjective symptoms since June, 1971. The lesions affect lower eyelids, forehead, cheeks, malar region, upper lip, chin and nasolabial folds symmetrically. Histopathological findings revealed conglomerated individual tubercles with prominent central caseation necrosis. He was given 600mg of INH and 12 mg of PAS daily per os for 2 months. The eruptions were healed gradually with pitted scars.
Cheek ; Chin ; Cicatrix ; Eyelids ; Forehead ; Humans ; Lip ; Male ; Nasolabial Fold ; Necrosis ; Young Adult