Treatment of persistent uveitis with Methotrexate (MTX) in a 35 years-old Korean male has been reported. The patient vision was HM in right eye and 0.02 in left eye on admission, and improved to 0.2 in right eye and 1.0 in left eye after MTX treatment for 45 days. A brief review of literatures has also been described.
Adult ; Humans ; Male ; Methotrexate* ; Uveitis*

Authors present two casas of familial metaphyseal dysplasia which was first described by Pyle as a skeletal disorder affecting the metaphyseal region of tubular bones. The cases reported here bear some resemblance to that of Bawkin and Krida.

Percutaneous transluminal angioplasty(PTA) were performed in three patients with atherosclerotic stenosis of subclavian arteries. The arteries were successfully dilated without complications during the procedure. All patients were asymptomatic during follow-up periods ranging from eight months to fifteen months after PTA.
Angioplasty* ; Arteries ; Constriction, Pathologic ; Follow-Up Studies ; Humans ; Subclavian Artery*

PURPOSE: To evaluate the diagnostic efficacy and complications of ultrasound-guided percutaneous renal biopsy using automatic biopsy gun in patients with pediatric diffuse renal disease. MATERIALS and METHODS: Using an 18G automatic biopsy gun, biopsies were performed on 97 pediatric patients with clinically suspicious diffuse renal disease. The acquired tissue specimens were analyzed by photomicroscopy, immunofluorescence, and electron microscopy to support the diagnosis. In the 97 biopsies, the success of the histologic diagnosis, number of glomeruli, and complication rates were retrospectively evaluated by analyzing the variable exams and clinical records. RESULTS: Adequate tissue for histologic diagnosis was obtained in 91 of 97 biopsies (94%) and the mean number of glomeruli was 9.6. Complications such as minute pain, gross hematuria, and small perirenal hematoma presented in 22 of the 97 biopsies (23%), all of which either improved within 5-72 hours or did not need specific treatment. CONCLUSION: Ultrasound-guided percutaneous renal biopsy using 18G automatic biopsy gun is an effective and safe method for the histologic diagnosis of pediatric diffuse renal disease without any major complication.
Biopsy* ; Diagnosis ; Fluorescent Antibody Technique ; Hematoma ; Hematuria ; Humans ; Microscopy, Electron ; Retrospective Studies

OBJECTIVE: The purpose of this study was to evaluate the MR spectrum and MR cholangiographic imaging findings of clonorchiasis. MATERIALS AND METHODS: We reviewed 26 patients with confirmed clonorchiasis by either stool tests (n=24) or surgery (n=2). MR imaging was performed on a 1.5 T system (GE Medical Systems, Milwaukee, WI) with a torso coil. Axial T1-and T2-weighted, gadolinium-enhanced dynamic images and MR cholangiography were obtained. Image analyses were used to identify abnormalities of the intrahepatic and extrahepatic bile ducts and the presence of hepatobiliary malignancy. All MR examinations were reviewed by the consensus of two abdominal radiologists. RESULT: Intrahepatic bile duct abnormalities were seen in 23 (89%) of the 26 patients. The most common finding was mild dilatation of the intrahepatic bile duct which was found in 21 (81%). "Too many intrahepatic ducts" were found in 16 (62%), wall enhancement and thickening in 21 (81%) and filling defects and ductal stricture in the intrahepatic bile duct in 6 (24%) and 3 (12%) patients, respectively. Extrahepatic ductal dilation was found in 5 (19%) and 9 (35%) revealed hepatobiliary malignancy. CONCLUSION: MR imaging revealed various findings of clonorchiasis, including dilatation, wall enhancement, stricture of the intrahepatic ducts and filling defect within the intrahepatic bile duct.
Adult ; Aged ; Cholangiography/methods ; Clonorchiasis/*diagnosis/radiography ; Female ; Human ; *Magnetic Resonance Imaging/methods ; Male ; Middle Aged

Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder that is characterized by proliferation of benign histiocytes, and this commonly involves the liver, spleen, lymph nodes, bone marrow and central nervous system (CNS). We report here on the CT and MR imaging findings in a case of CNS HLH that showed multiple ring enhancing masses mimicking abscess or another mass on the CT and MR imaging.
Tomography, X-Ray Computed ; Male ; Lymphohistiocytosis, Hemophagocytic/*diagnosis/drug therapy/radiography ; Humans ; Diffusion Magnetic Resonance Imaging ; Diagnosis, Differential ; Child, Preschool ; Central Nervous System Diseases/*diagnosis/drug therapy/radiography

Behcets disease is a chronic systemic disease of unknown etiology, which is characterized by the recurrent orogenital ulcers, eye involvement and skin manifestations. In addition to the major symptoms, it includes arthritis, vasculitis, neurologic manifestations and gastrointestinal lesions. We report a case of Behcets disease associated with intestinal ulcers. The patient, a 45-year-old female, who had been treated under the diagnosis of Behcets disease for 4 years, presented with swallowing difficulty, vaginal discharge and persistent right lower abdominal pain. Colonoscopic examination showed multiple ulcers on the ileocecal region which is reported as the most common site of gastrointestinal Behcets disease. Gastrointestinal evaluation can be useful in diagnosis of Behcets disease, especially in a patient with gastrointestinal symptoms.
Abdominal Pain ; Arthritis ; Deglutition ; Diagnosis ; Female ; Humans ; Middle Aged ; Neurologic Manifestations ; Skin Manifestations ; Ulcer* ; Vaginal Discharge ; Vasculitis

We examined the morphological maturation of amacrine cells expressing neurokinin 1 (NK1) receptor, whose ligand is substance P, in the rat retina, focusing on the period from postnatal day 5 (P5) when the outer plexiform layer is formed, to postnatal day 13 (P13) when the eyes open, with immunohistochemistry using a specific antiserum against NK1 receptor, and we compared maturing NK1 receptor-immunoreactive (NK1 receptor-IR) amacrine cells with adult one. In the adult retina, numerous NK1 receptor-IR amacrine cells were located in the inner part of the inner nuclear layer (INL) adjacent to the inner plexiform layer (IPL), and their processes emerging from the somata branched and stratified at 1, 2, and 5 strata of within the IPL. NK1 receptor-IR amacrine cells were already observed at P5. The cell bodies were located in the inner INL away from the IPL and their processes branched and formed two distinct bands in the IPL. Afterwards, somata of NK1 receptor-IR amacrine cells moved toward the inner part of the INL, and thus, were located in the INL adjacent to the IPL. Their processes formed three distinct bands at P10 and then, at P13, three bands occupied the same strata as those of the adult, which were posed at 1, 2, and 5 strata of the IPL. During the postnatal development, most of NK1 receptor-IR amacrine cells directly extended one or a few primary dendrites toward the IPL and formed the strata. However, some of the labeled cells located at the outermost row had horizontal processes emerging from their primary dendrites, and these horizontal processes branched and formed plexuses in the INL. The NK1 receptor-IR amacrine cells with horizontal processes were frequently observed at P7, rarely at P10, and not at P13 and in the adult. These results indicate that the NK1 receptor-IR amacrine cells of the rat retina morphologically mature by way of migration of their somata within the INL and formation of distinct processes during postnatal development, and suggest that they morphologically and functionally complete the maturation process about the time of P13.
Adult ; Amacrine Cells* ; Animals ; Dendrites ; Humans ; Immunohistochemistry ; Rats* ; Retina* ; Substance P

PURPOSE: The purpose of this study was to evaluate the usefulness of diffusion tensor imaging (DTI) in the grading of gliomas. MATERIALS AND METHODS: DTI was performed in 24 patients with histologically confirmed brain gliomas. After placing the regions of interest (ROI) in the tumor center, tumor border, white matter adjacent to tumor, and normal-appearing white matter (NAWM) of the contralateral hemisphere, the FA values were measured. The size of the ROI was found to be 61 ml. In addition, the FA ratios were calculated for the ROIs in relation to the NAWM of the contralateral hemisphere. RESULTS: The mean FA ratios in patients with grade II gliomas were 0.348 for the tumor center, 0.564 for the tumor border, and 0.897 for the white matter adjacent to the tumor. For patients with grade III gliomas, the mean FA values were 0.247, 0.346, 0.782, respectively. Further, for patients with grade IV gliomas, the mean FA values were 0.204, 0.226, 0.336, respectively. The differences in the FA ratios between the grade II and III tumors were significant in the tumor center and tumor border (p = 0.005, p = 0.002, respectively). Moreover, the differences in the FA ratios between the grade III and IV tumors were significant in the tumor border and white matter adjacent to the tumor (p = 0.004, p = 0.004, respectively). CONCLUSION: DTI is a non-invasive imaging modality that may provide valuable information for the pre-operative grading of gliomas.
Brain ; Brain Neoplasms ; Diffusion Magnetic Resonance Imaging ; Diffusion Tensor Imaging ; European Continental Ancestry Group ; Glioma ; Humans

We report a case of an intraparenchymal schwannoma of the left parietal lobe. A 51-year-old woman was admitted to our hospital with complaints of intermittent headaches. Computed tomography and magnetic resonance images revealed a 1.3 cm sized intra-axial homogeneous enhancing mass in the left parietal lobe. The lesion was pathologically confirmed to be a schwannoma.
Brain Neoplasms ; Female ; Headache ; Humans ; Magnetic Resonance Spectroscopy ; Middle Aged ; Neurilemmoma ; Parietal Lobe