1.Implication of Neoadjuvant Chemotherapy for the Management of Patients with Locally Advanced Cervical Cancer.
Jae Wook KIM ; Eun Gyung CHOI ; Young Tae KIM
Korean Journal of Obstetrics and Gynecology 2000;43(8):1375-1383
No abstract available.
Drug Therapy*
;
Humans
;
Uterine Cervical Neoplasms*
3.MRI of cervical carcinoma: before and after chemotherapy.
Jung Sik KIM ; Soo Jhi SUH ; Tae Jin CHOI ; Tae Sung LEE ; Young Wook SUH
Journal of the Korean Radiological Society 1992;28(6):927-934
To evaluate usefulness of MR in assessment of tumor response to the chemotheraphy, we prospectively studied cases of cervical carcinoma with more then 2.5cm in diameter or stage IIb or more. Three courses of chemotherapy were performed with cisplatin and 5 F-U. MR images were obtained both before and after chemotherapy. Nine of 13 patients were undertaken radical hysterectomy after chemotherapy and MR examination. MR volumetry, stage and depth of stromal invasion were compared before and after chemotherapy. And in 9 patients who underwent radical hysterectomy, comparison of pathologic and MR imaging findings were also done. @ES The results were following. @EN 1) All tumors dectrased in volume (m=80.5%). 2) Five tumors (38.5%) reduced in stage, IB→CIS(1); IIA→CIS(1), IIA→IB(2), IIB→IB(1). 3) Depth of stromal invasion in MRI correlated well with that of histo-pathologic specimen in 7 of the 9 patients. Conclusively MR imaging is useful in assessement of tumor response to chemotherapy.
Cisplatin
;
Drug Therapy*
;
Humans
;
Hysterectomy
;
Magnetic Resonance Imaging*
;
Prospective Studies
4.Peritonitis during CAPD in children.
Ja Wook KOO ; Tae Sun HA ; In Seok LIM ; Il Soo HA ; Hae Il CHEONG ; Yong CHOI ; Kwang Wook KO
Korean Journal of Nephrology 1991;10(3):379-386
No abstract available.
Child*
;
Humans
;
Peritoneal Dialysis, Continuous Ambulatory*
;
Peritonitis*
5.A clinical study of continuous ambulatory peritoneal dialysis in childhood.
Tae Sun HA ; Hye Won PARK ; Ja Wook KOO ; In Seok LIM ; Hae Il CHEONG ; Yong CHOI ; Kwang Wook KO
Journal of the Korean Pediatric Society 1991;34(3):363-370
No abstract available.
Child
;
Humans
;
Kidney Failure, Chronic
;
Peritoneal Dialysis, Continuous Ambulatory*
6.A clinical study of continuous ambulatory peritoneal dialysis in childhood.
Tae Sun HA ; Hye Won PARK ; Ja Wook KOO ; In Seok LIM ; Hae Il CHEONG ; Yong CHOI ; Kwang Wook KO
Journal of the Korean Pediatric Society 1991;34(3):363-370
No abstract available.
Child
;
Humans
;
Kidney Failure, Chronic
;
Peritoneal Dialysis, Continuous Ambulatory*
7.Comparison of MAST Chemiluminescent Assay(MAST-CLA) with Skin Prick, Test in Patients with Atopic Dermatitis.
In Wook LEE ; Tae Hyun KIM ; Sung Ku AHN ; Eung Ho CHOI
Korean Journal of Dermatology 1999;37(3):297-304
BACKGROUND: Allergic reactions are known to be associated with symptomatic aggravation of atopic dermatitis. Skin prick tests were used as a routine in vivo screening test for the evaluation of allergic patients. Many tests to detect specific IgE antibody including RAST, FAST and MAST chemilu-minescent assay (MAST-C~LA) were also used. Previous studies revealed that the results of skin prick tests and MAST-CLA were well correlated in patients with asthma, allergic rhinitis and urticaria. OBJECTIVES: The purpose of this study was to evaluate the effectiveness of MAST-CLA compared with skin prick tests in patients with atopic dermatitis. METHODS: We performed the chemiluminescent assay with 35 allergens and skin prick tests with 23 allergens common with allergens used in MAST-CLA in 34 patients with atopic dermatitis. The positive reaction rate of allergens in each test and sensitivity, specificity, efficiency, positive predictive value and negative predictive value of MAST-CLA to the skin prick test were evaluated and MAST net volts of serum total IgE was compared with PRIST.
Allergens
;
Asthma
;
Dermatitis, Atopic*
;
Humans
;
Hypersensitivity
;
Immunoglobulin E
;
Luminescent Measurements
;
Mass Screening
;
Rhinitis
;
Sensitivity and Specificity
;
Skin*
;
Urticaria
8.Acute dapsone intoxication: The dosage of activated charcoal and methylene blue.
Sung Pil CHUNG ; Tae Sik HWANG ; Sung Wook CHOI ; Seung Ho KIM ; Hahn Shick LEE
Journal of the Korean Society of Emergency Medicine 1997;8(2):277-282
BACKGROUND: Methemoglobinemia(MetHb) induced by dapsone overdose is not uncommon in Korea, especially in rural area. For treatment of dapsone-induced methemoglobinemia, methylene blue(MB) and activated charcoal(AC) should be used. To date, no reports have compared the amount of MB used between MB alone with MB & AC combined group(MB+AC). And also between moderate (MetHb<35%) and severe (MetHb>35%) intoxicated group defined by initial MetHb level. Authors hypothesized that less amount of MB can be used if MB and AC was used together and larger amount of MB is necessary to reduce MetHb level to asymptomatic level in severely intoxicated group. METHODS: From Jan 1990 to Dec 1996, a total of 54 patients who received treatment for dapsone intoxication were subject of study, The study was done retrospective chart analysis for initial MetHb level, total amount of MB and AC. Wilcoxon rank sum test and Chi-sqiare test was used to compare the total dosage of MB used for each group. Linear regression analysis was used between initial MetHb and the total amount of MB. Results were considered statistically significant when p<0.05. RESULTS: For MB alone and MB+AC group, the differences in total amount of MB used were statistically significant with mean dosage of 7.14+/-1.1mg/kg and 4.28+/-0.7mg/kg, respectively. And total amount of MB used between moderate and severe intoxicated group, the differences were statistically significant with mean dosage of 5.16+/-1.1mg/kg vs. 10.98+/-1.9mg/kg, respectively. There was significant correlation between initial MetHb level (X) and the amount of methylene blue (Y), Y=0.3X-2.42 (r2=0.41, p=0.0001) in MB alone, Y=0.186X-1.95(r2=0.21, p=0.034) in MB+AC respectively. CONCLUSION: For methemoglobinemia induced by dapsone, total amount of MB can be reduced especially in severe Intoxicated group if AC use was combined in treatment modality. There was significant correlationship between initial MetHb level and total amount of MB used.
Charcoal*
;
Dapsone*
;
Humans
;
Korea
;
Linear Models
;
Methemoglobinemia
;
Methylene Blue*
;
Retrospective Studies
9.Evaluation of Effectiveness and Safety of Pazeron Treatment of Infection in Obstetric and Gynecology; Phase IV Clinical Study.
Jae Wook KIM ; Eun Kyoung CHOI ; Yong Won PARK ; Young Tae KIM
Korean Journal of Obstetrics and Gynecology 1999;42(9):2071-2077
OBJECTIVES: This study was planned to evaluate the clinical efficacy and safety of cefazedone in the treatment of patients with infectious disease in the field of obstetrics and gynecology. METHOD: Cefazedone was used in 20 patients with infectious disease in obstetrics and gynecology, who visited the department of obstetrics and gynecology, Yonsei university college of medicine, from June 1998 through July 1999. RESULTS: The mean age of the patients was 42.5 years(range of 18 to 68 years) and 17 of patients were diagnosed as pelvic inflammatory disease(PID), 2 were urinary tract infection due to huge ovarian tumor, and 1 was Bartholin's gland abscess. Cefazedone was proven its efficacy in treating infections of obstetrics and gynecology so as to reach 100% of response rate. The cefazedone was sensitive to all isolated organisms - G. vaginalis, E. coli, Staphylococcus, coagulase (+), etc. In the course of treatment, 1 patient experienced mild nausea, another 1 patient complained mild diarrhea, and another 1 patient showed transient leukopenia but their symptoms and signs were disappeared with only conservative management. There was no significant renal and hepatic function changes. CONCLUSION: Our results suggest that cefazedone is relatively effective in treating infections of obstetrics and gynecology to show excellent antibacterial effects and low incidence of complications.
Abscess
;
Coagulase
;
Communicable Diseases
;
Diarrhea
;
Gynecology*
;
Humans
;
Incidence
;
Leukopenia
;
Nausea
;
Obstetrics
;
Staphylococcus
;
Urinary Tract Infections
10.Expression of Vascular Endothelial Growth Factor : Clinical Implications in Cervical Neoplasia.
Eun Gyung CHOI ; Jae Wook KIM ; Young Tae KIM ; Nam Hoon JO
Korean Journal of Obstetrics and Gynecology 2000;43(12):2254-2262
No abstract available.
Vascular Endothelial Growth Factor A*