No abstract available.
Drug Therapy* ; Humans ; Uterine Cervical Neoplasms*

No abstract available.
Occupational Health*

To evaluate usefulness of MR in assessment of tumor response to the chemotheraphy, we prospectively studied cases of cervical carcinoma with more then 2.5cm in diameter or stage IIb or more. Three courses of chemotherapy were performed with cisplatin and 5 F-U. MR images were obtained both before and after chemotherapy. Nine of 13 patients were undertaken radical hysterectomy after chemotherapy and MR examination. MR volumetry, stage and depth of stromal invasion were compared before and after chemotherapy. And in 9 patients who underwent radical hysterectomy, comparison of pathologic and MR imaging findings were also done. @ES The results were following. @EN 1) All tumors dectrased in volume (m=80.5%). 2) Five tumors (38.5%) reduced in stage, IB→CIS(1); IIA→CIS(1), IIA→IB(2), IIB→IB(1). 3) Depth of stromal invasion in MRI correlated well with that of histo-pathologic specimen in 7 of the 9 patients. Conclusively MR imaging is useful in assessement of tumor response to chemotherapy.
Cisplatin ; Drug Therapy* ; Humans ; Hysterectomy ; Magnetic Resonance Imaging* ; Prospective Studies

No abstract available.
Child* ; Humans ; Peritoneal Dialysis, Continuous Ambulatory* ; Peritonitis*

No abstract available.
Child ; Humans ; Kidney Failure, Chronic ; Peritoneal Dialysis, Continuous Ambulatory*

No abstract available.
Child ; Humans ; Kidney Failure, Chronic ; Peritoneal Dialysis, Continuous Ambulatory*

PURPOSE: We evaluated the effect of vitrectomy and arteriovenous adventitial sheathotomy for branch retinal vein occlusion (BRVO) according to operation timing and obstruction site. METHODS: We performed vitrectomy and arteriovenous adventitial sheathotomy in 14 eyes with BRVO. Patient selection criteria were foveal involvement of macular hemorrhage or macular edema and a best corrected visual acuity (BCVA) of 0.1 or less. We compared 7 eyes with symptom duration of 2 months or less (Group 1) and 7 eyes with symptom duration of more than 2 months (Group 2). We analyzed 7 eyes for which the obstruction site was 1 disc diameter (DD) or less from the disc margin (Group A) and 7 eyes of more than 1 DD (Group B). RESULTS: Seven of 14 eyes (50%) had visual improvement. Six eyes of Group 1 (86%) had visual improvement and Group 1 had better visual improvement than Group 2. There was a statistically significant difference between Groups 1 and 2 (p=0.029). Five eyes of Group A (71%) had visual improvement and Group A had better visual improvement than Group B. There was no statistically significant difference (p=0.286). CONCLUSIONS: In the case of foveal involvement of macular hemorrhage or macular edema and a BCVA of 0.1 or less, vitrectomy and arteriovenous adventitial sheathotomy are effective in early BRVO.
Hemorrhage ; Macular Edema ; Patient Selection ; Retinal Vein Occlusion* ; Retinal Vein* ; Retinaldehyde* ; Visual Acuity ; Vitrectomy*

No abstract available.
Carcinoma, Squamous Cell* ; Cisplatin* ; Drug Therapy, Combination* ; Female ; Ovary* ; Paclitaxel*

Alterations in the expression of genes that control the cell cycle may be of critical importance in tumorigenesis and malignant transformation. The major regulatory events leading to cell proliferation occur in Gl phase of cell cycle, and the deregulated expression of Gl cyclins is related to oncogenesis. Cyclins Dl and E play important roles in the progression of cell through Gl phase of the cell cycle. Amplification and/or overexpression of the cyclin Dl gene and aberrant expression of cyclin E has been described in various forms of human cancer. However, the role of cyclins Dl and E in cervical cancer has been poorly defined. In this study, we examined the expression of cyclins Dl and E by Northern blot technique and the status of human papil- lomavirus(HPV) type 16 and 18 by polymerase chain reaction in 25 cases of cervical carcinoma to explore the relationship between cyclins Dl and E and cervical cancer. We found cyclin Dl expression showed down-regulated expression in cervical cancer but cyclin E expression was increased in cancer group. Other clinicopathological prognostic factors were not correlated with cyclins D1 and E expression. Further study based on larger numbers of cases with correlation of cyclins D1 and E status and survival data will be needed to elucidate the use of cyclin expressions as prognostic factor.
Blotting, Northern ; Carcinogenesis ; Cell Cycle ; Cell Proliferation ; Cyclin E ; Cyclins* ; Humans ; Polymerase Chain Reaction ; Uterine Cervical Neoplasms

No abstract available.