This purpose of the present study was to inestigate the correlations of malocclusion between the mother and the offression and thus heritable features from mother to her offspring. Dental impression was taken of the both jaws of 73 mothers and their sons and 109 mothers and their daughters, and the measurement was obtained from the models. The correlation coefficient of the mesio-distal diameters of teeth and that of occlusion and arch variable was calculated from the mesurement. After the data was analyzed and estimated, the following results were obtained: 1. It was evident that the tooth size of the offspring was influenced from their mother. 2. It was evident that the occlusion, the arch size and shape of the offspring were influenced from their mother. 3. There was not the marked difference between the heredity of occlusion variable and arch variable on the mother-offspring relationship. 4. The correlation of the lower intercanine width and the lower available space discrepancy between the mother and the offspring were greatly influenced with the environmental factor.
Heredity ; Humans ; Jaw ; Malocclusion* ; Mothers* ; Nuclear Family ; Tooth ; Wills*

No abstract available.
Heat-Shock Proteins* ; Hot Temperature*

No abstract available.
Heat-Shock Proteins* ; Hot Temperature*

Backgound: The placement of stents in coronary arteries has been shown to reduce acute closure and restenosis in comparison to balloon angioplasty. However, clinical use of intracoronary stents is impeded by the subacute stent thrombosis and hemorrhagic complications associated with the anticoagulant regimen. It's known that the complete stent deployment with high pressure inflation and new antiplatelet agents are effective in reduction of subacute thrombosis and hemorrhage. So we evaluated initial results (success and complication rate) after high pressure-stent deployment with new anticoagulation protocol. METHODS: One hundred and ninety one patients with 201 lesions were treated with 231 stents of various types. The high pressure balloon inflation and antiplatelets agents were used in all cases. Final high pressure balloon inflation guided by IVUS were performed in 23 consecutive cases with incomplete stent deployment according to angiographic findings. RESULTS: 1) The indications of stenting (n=210) were De novo in 124 (59%), bailout procedure in 57 (27%), suboptimal result after PTCA in 19 (8%), and restenosis after PTCA in 14 (6%). The location of lesions were LAD in 101, RCA in 67, circumflex in 28, ramus intermedius in 3, and LMT artery in 2 lesions. Angiographic morphologic characteristics were type A in 2, type B in 158 (B1: 57, B2: 101), and type C in 22 lesions. 2) The angiographic and clinical success rate was 96% (192/201) and 92% (186/201) respectively. 3) In angiographic analysis, the baseline average reference vessel dirmeter was 3.33+/-0.35 mm. Baseline minimum lumen diameter (MLD) was 0.58+/-0.29 mm, with baseline percent diameter stenosis of 82.86+/-8.64%. The final stent diameter was 3.37+/-0.29 mm, with mean final percent stenosis of 0.63+/-8.25. The mean MLD after stenting was significantly increased (p<0.001). The mean MLD within stent increased 14%, from 2.91+/-0.39 mm at the nominal balloon inflation (inflation pressure=7 atm) to 3.37+/-0.29 mm at high pressure balloon inflation (inflation pressure <0A65B>12atm) (p<0.001). The length of lesions in GR I (cook), GR II, and Micro II stents were significantly longer than ones in PS, Cordis, Wiktor, Nir (p<0.001). 4) In intravascular ultrasound analysis, the mean lumen CSA at the tightest point within stent increased 11%, from 8.4+/-2.4 mm2 at the intial intravascular ultrasound to 9.4+/-2.1 mm2 at the final intravascular ultrasound (p<0.001). 5) The procedural and postprocedural complications were 2 acute closures associated with AMI and emergent CABG, 1 subacute closure which was revascularized by bail out stenting, 5 major hemorrhage requiring transfusion associated with 1 CVA and 2 metabolic acidosis induced by acute renal failure, and 5 death. CONCLUSION: The high pressure stent deployment procedure and new anticoagulation protocol associating tidopidine and aspirin without coumadin or prolonged heparin infusion allow us to obtain an acceptably low subacute thrombosis or bleeding complication rate. These results are encouraging and allow a wide use of coronary stenting.
Acidosis ; Acute Kidney Injury ; Angioplasty, Balloon ; Arteries ; Aspirin ; Constriction, Pathologic ; Coronary Vessels* ; Hemorrhage ; Heparin ; Humans ; Inflation, Economic ; Platelet Aggregation Inhibitors* ; Stents* ; Thrombosis ; Ultrasonography ; Warfarin

PURPOSE: There were many studies on the distributions of the retinal ganglion cells(RGC) in the experimental model of the retinal ischemia. RGC was known to be more sensitive to the ischemic injury than the other types of the retinal cells. So, we would identify the changes of the retinal ganglion cell morphologies and distribution after the iatrogenic retinal ischemia induced by intraocular pressure(IOP) elevation. METHODS: Eight pigmented and six white rabbits were used and retinal ischemia was induced by increasing IOP higher than 120 mmHg for 60 minutes. Electroretinogram were recorded at 6 days or 13 days, and histologic findings were observed at 7 or 14 days. RESULTS: After 7 days, RGC densities decreased, cytoplasmic staining disappeared, and the intranuclear hyperpigmentation was noted. RGC densities decreased significantly at 14 days. In the vertical retinal section, some flattening of retinal ganglion cell layer and inner plexiform layer was observed. Changes in the cellular morphologies were prominent. CONCLUSIONS: It may be more appropriate to examine both the retinal whole-mount and the vertical tissue section for the estimatation of the changes of retinal ganglion cell layer in the pressure-induced retinal ischemia.
Cytoplasm ; Ganglion Cysts* ; Hyperpigmentation ; Ischemia ; Models, Theoretical ; Rabbits ; Retina* ; Retinal Ganglion Cells ; Retinaldehyde*

No abstract available.
Cyclosporine* ; Scleredema Adultorum*

Mitral valvular orifice area is important for the evaluation of prognosis and treatment of patients with mitral valvular stenosis. Until recently, Gorlin's formula using cardiac catheterization has been utilized in the measurement of mitral valve area, but it is invasive and impractical to examine repeatedly. Recently 2-Dimensional echocardiography appeared to be a practical and useful substitute in measurement of valve area and also it is economical and has no risk to patients. In 31 patients with mitral valvular stenosis examined at the echocardiography room of Busan national University Hospital from March 1982 to March 1983, we measured the mitral valve area with 2-Dimensional echocardiography and evaluated its relationship with the left ventricular functions measured on M-mode echocardiogram. Among many parameters on M-mode measurements EF slope, excursion amplitude and the ratio of left atrial dimension to aortic root dimension were rather helpful for the assessment of severity of mitral valvular stenosis than other parameters. And each relationship with the valve area showed correlation coefficient of 0.60, 0.05 and -0.58, respectively.
Busan ; Cardiac Catheterization ; Cardiac Catheters ; Constriction, Pathologic* ; Echocardiography* ; Humans ; Mitral Valve* ; Prognosis ; Ventricular Function, Left

One hundred normal optic discs were analysed by fluorographic fundus pictures. Horizontal diameter of optic disc was set as 10. The following results were obtained. 1) The vertical diameter of optic disc was larger than the horizontal one. (10.77 : 10). 2) The ratio of diameters of cenitral retinal vein(CRV) was 1 : 1.51 before and 1 : 1.47 after fluorescein injection. 3) The central retinal artery(CRA) located nasal to the CRV in most cases. 4) In nearly half of cases, physiologic cups located at the nasal portion of optic discs. 5) The average size of physologic cup was 2.90. 6) The cilioretinal artery was detected in 58% of cases in which one cilioretinal artery was found in 42%, two was found in 16%. 7) The CRA made branchings more than retinal veins (7.74 : 5.48) and total sum of diameters of retinal artery was larger than that of retinal vein at the disc margin.
Arteries ; Fluorescein ; Retinal Artery ; Retinal Vein ; Retinaldehyde

Uterine fibroids are the most common benign tumor of the female genital organ. Menorrhagia is the most common symptom associated with uterine fibroid. Since the first suggestion that embolization of uterine arteries might have a role in the management of fibroids by Ravina et al (France) in 1995,3 uterine artery embolization for management of fibroids has been performed actively in United states, United Kindom and Japan, and excellent therapeutic results have been reported. We have performed uterine artery embolization on patients with symptomatic fibroids or adenomyosis since August 1998. There have been few case reports of expelled fibroids out of vagina after uerine artery embolization, so we present a case in which successful embolization in woman with submucosal myoma resulted in a subsequent vaginal expulsion.
Adenomyosis ; Arteries ; Female ; Genitalia ; Humans ; Japan ; Leiomyoma* ; Menorrhagia ; Myoma ; United States ; Uterine Artery Embolization* ; Uterine Artery* ; Vagina

To predict eruptive path of maxillary canine, 13 male and 11 female malocclusions were longitudinally studied for 4 years. And to study frequency and distribution of impaction of maxillary canine, 1500 malocclusions were studied. The path, velocity and duration of maxillary canine eruption were determined by periodic angular and linear measurement using periodic orthopantomograms and cephalograms. The following results were obtained. 1. Maxillary canine was erupted with 14.5degrees distal tipping from initial stage 98.1degrees to final stage 83.6degrees of axial inclination on orthopantomogram. 2. Eruptive velocity of maxillary canine was fastest on stage 4, and mean eruptive velocity was 10.5mm per year on stage 4. 3. Eruption of maxillary canine was completed 12 year 5 months in male and 11 years 8 months in female. 4. To predict the duration for eruption completion by position of maxillary canine on cephalogram, regression equation was obtained. 5. Frequency of impaction of maxillary canine was 1.47% in malocclusion and more frequent in male. Distribution of buccal and palatal, right and left impaction was no different, but unilateral impaction was more frequent.
Female ; Humans ; Longitudinal Studies* ; Male ; Malocclusion