No abstract available.
Drainage* ; Humans ; Hydrocephalus*

BACKGROUND AND OBJECTIVES: We aimed to evaluate the clinical manifestation and treatment outcome of the nasal cavity squamous cell carcinoma (SCC) and compared its survival rate with that of the maxillary sinus (MS) SCC. SUBJECTS AND METHOD: Thirty two patients who were diagnosed as nasal cavity SCC or ethmoid sinus SCC between 1984 and 2005 were selected. These patients were referred to as the intranasal (IN) SCC group. Ten prognostic factors were evaluated in terms of survival rate and recurrence. The survival rate of 61 patients who were diagnosed as MS SCC was compared with that of the IN SCC. RESULTS: Chief complaints of the patients with IN SCC were nasal obstruction (40.4%), epistaxis (25.0%), and rhinorrhea (13.5%). The 5 year survival rate of IN SCC was 44.6% and the 5 year disease free survival rate was 27.7%. The most important prognostic factor was T stage (p<.001). The 5 year survival rate of MS SCC was 55.4%, and it was statistically not different from that of the IN SCC (p=.472). In the T1, T2, T3 stages, the 5-year-survival rate of the IN SCC was similar to that of MS SCC (p=.637). But in the T4 stage, IN SCC tended to have a worse prognosis (p=.074). CONCLUSION: The prognosis of IN SCC was similar to that of the MS SCC. However, MS SCCs were detected in a more advanced stage and T4 stage of the IN SCC had a worse prognosis compared to the same stage of MS SCC.
Carcinoma, Squamous Cell* ; Disease-Free Survival ; Epistaxis ; Ethmoid Sinus* ; Humans ; Maxillary Sinus ; Nasal Cavity* ; Nasal Obstruction ; Paranasal Sinuses ; Prognosis ; Recurrence ; Survival Rate ; Treatment Outcome

No abstract available.
Mediastinal Neoplasms ; Teratoma*

BACKGROUND: Hepatitis B virus(HBV) DNA integration is one of the cause of hepatocellular carcinoma (HCC). Epidemiologic evidences indicate that HBV infection is associated with the high risk of development of HCC. We wanted to evaluate the HBV DNA integration in hepatocellular carcinoma. So we detected HBV DNA by PCR in aseptically obtained 37 HCC tissues. METHODS: A total 37 surgical specimens from HCC patients were evaluated. Patient's serologic findings were analyzed retrospectively. Serologic markers were tested by radioimmunoassay. Genomic DNA was extracted from HCC paraffin blocks by microwave oven method. PGR was done. RESULTS: The sensitivity of HBV DNA PCR was 100 fg. Among 37 Patients tested, 30 cases of HCC patients had HBV DNA in their liver tissue. Among 25 HBs Ag positive patients, 23 had PCR positive results. All of the anti-HBc positive patients had HBV DNA. CONCLUSIONS: These findings are highly suggestive of HBV infection in the development of hepatocellular carcinoma. Detection of HBV DNA in patients with hepatocellular carcinoma is highly suggestive of HBV infection in the development of hepatocellular carcinoma.
Carcinoma, Hepatocellular* ; DNA ; Hepatitis B virus* ; Hepatitis B* ; Hepatitis* ; Humans ; Liver ; Microwaves ; Paraffin ; Polymerase Chain Reaction* ; Radioimmunoassay ; Retrospective Studies

No abstract available.
Cardioplegic Solutions* ; Ischemia*

OBJECTIVES: This study was carried out to investigate the clinical availability of topographic auditory event related potential P300 as a biological marker in children with attention deficit hyperactivity disorder(ADHD). METHODS: The subjects were composed of children with ADHD(n=22:16 boys, 6 girl s:mean age=89.8+/-17.1months) and normal controls(n=20:12 boys, 8 girls:mean age=90.6+/-16.8months). Topographic auditory event related potential was measured by "oddball paradigm", and the latencies and amplitudes of P300 of both groups were determined by Global Field Power Measurement. After 8 weeks treatment with methylphenidate, P300 of ADHD children were also measured. RESULTS: Both P300 latency and amplitude were not different between ADHD children after treatment and normal controls, but significantly different between ADHD children before treatment and normal controls, and between before and after treatment of ADHD children. CONCLUSIONS: The results implicate that the latency and amplitude of P300 may be considered as state markers of ADHD.
Attention Deficit Disorder with Hyperactivity* ; Biomarkers ; Child* ; Evoked Potentials* ; Female ; Humans ; Methylphenidate

No abstract available.

For the past two years, nephropexy using PCN was underwent in 9 cases of nephroptosis (8 patients) with variable degrees of flank pain. All were female and 6 on right, 1 on left and 1 on bilateral. All patients had a very mobile kidney and exact distance of movement measured on the film was greater than 6cm (6 to 15 cm). After this operation, 14-20 Fr. nephrostomy catheter was indwelled for about two weeks. All patients were followed at least 3 months(3 to 32, median 17 months). We followed the patients with symptom relief and IVP after 3 months. Nephropexy was regarded as success if she remained asymptomatic for more than 3 months. Five cases were successful and four cases felt recurrent flank pain within 1 month after the surgery. Among four cases of recurrence, one had repeated PCN and got successful result, another had open nephropexy and the others have been followed so far So overall success rate was 67% (6/9). In conclusion, nephropexy using PCN is less invasive, needs shorter period of admission and leaves ignorable scars postoperatively. Furthermore it can be repeated even in the case of failure or recurrence, which would make this new technique available as the first step for the surgical treatment of nephroptosis. And the success rate could be increased if the nephrostomy tract is dilated upto 30 Fr. and the PCN catheter is placed about 4 weeks.
Catheters ; Cicatrix ; Female ; Flank Pain ; Humans ; Kidney ; Nephrostomy, Percutaneous* ; Pregnenolone Carbonitrile ; Recurrence

PURPOSE: Administration of antiretroviral drugs to mothers and infants significantly decreases mother-to-child human immunodeficiency virus (HIV) transmission; cesarean sections and discouraging breastfeeding further decreases this risk. The present study confirmed the HIV status of babies born to mothers infected with HIV and describes the characteristics of babies and mothers who received preventive treatment. METHODS: This study retrospectively analyzed medical records of nine infants and their mothers positive for HIV who gave birth at Korea University Ansan Hospital, between June 1, 2003, and May 31, 2013. Maternal parameters, including HIV diagnosis date, CD4+ count, and HIV ribonucleic acid (RNA) copy number, were analyzed. Infant growth and development, HIV RNA copy number, and HIV antigen/antibody test results were analyzed. RESULTS: Eight HIV-positive mothers delivered nine babies; all the infants received antiretroviral therapy. Three (37.5%) and five mothers (62.5%) were administered single- and multidrug therapy, respectively. Intravenous zidovudine was administered to four infants (50%) at birth. Breastfeeding was discouraged for all the infants. All the infants were negative for HIV, although two were lost to follow-up. Third trimester maternal viral copy numbers were less than 1,000 copies/mL with a median CD4+ count of 325/microL (92-729/microL). Among the nine infants, two were preterm (22.2%) and three had low birth weights (33.3%). CONCLUSION: This study concludes that prophylactic antiretroviral therapy, scheduled cesarean section, and prohibition of breastfeeding considerably decrease mother-to-child HIV transmission. Because the number of infants infected via mother-to-child transmission may be increasing, studies in additional regions using more variables are necessary.
Breast Feeding ; CD4 Lymphocyte Count ; Cesarean Section ; Diagnosis ; Female ; Growth and Development ; Gyeonggi-do ; HIV Infections ; HIV* ; Hospitals, Teaching* ; Humans ; Infant ; Infant, Low Birth Weight ; Infant, Newborn ; Infectious Disease Transmission, Vertical ; Korea ; Lost to Follow-Up ; Medical Records ; Mothers ; Parturition ; Postnatal Care ; Pregnancy ; Pregnancy Trimester, Third ; Retrospective Studies ; RNA ; Zidovudine

Hypertensive encephalopathy is a medical emergency that is usually presented with manifestating headache, nausea, and visual disturbance. The disease predominantly involves the parieto-occipital white matter. Although cerebellar lesion accompanying hydrocephalus has been occasionally described in the literature, medical management has been sufficient for relieving the posterior fossa hypertension. In the present case, we report a patient who was diagnosed with primary hypertensive cerebellar encephalopathy refractory to medical management and who was successfully treated by surgical decompression of the posterior fossa. A pathologic microscopic inspection of the tissue specimen confirmed hypertensive vascular change.
Decompression* ; Decompression, Surgical ; Emergencies ; Headache ; Humans ; Hydrocephalus ; Hypertension ; Hypertensive Encephalopathy ; Nausea