BACKGROUND: The relation between clinical characteristics and a change of thymid functions in patients with hyperemesis gavidarum(HO) has not been well described. In order to clarify this characteristics, we evaluated thyroid function in patients with HG and compared the relationship to clinical characteristics of gestational thyrotoxicosis and hyperemesis. METHODS: From March, 1991, to April, 1997, 20 patients were admitted to the department of obstetrics in Chonbuk National University Hospital because of HG. We examined clinical characteristics of patients with HG(age, marrital age, levels of educations, obstetrical history, gestational duration, vomiting duration, degree of weight loss, infant's birth weights, duration of pregnancy). Thyroid functions, liver functions and serum electrolytes was measured. Also, we compared to the clinical characteristics of patients with HG according to thyroxine concentration. RESULTS: An increased free thyroxine concentration was observed m 65% of 20 pregnancies complicated by severe HG. The level of serum ALT was greater in thyrotoxicosis patients(91.2+-76.6 IU/L, mean +-SD) than normothyroxemic patients(20.3+-12.7 IU/L, P=0.027). Also, increased level of serum AST was observed in patients with HG. In patients with thyrotoxicosis, the long durations of vomiting was observed. CONCLUSIONS: Increased free thyroxine concentration is found in severe HG. Because the relatively higher risk for thyrotoxicosis, patients with severe hyperemesis, they must be evaluated about thyroid functions.
Birth Weight ; Electrolytes ; Humans ; Jeollabuk-do ; Liver ; Obstetrics ; Pregnancy ; Thyroid Gland* ; Thyrotoxicosis ; Thyroxine ; Vomiting ; Weight Loss

Many studies for LPS-induced cytokines, chemokines gene expressions have been reported, but results are highly diverse. The dose of LPS used, cell type studied or other technical factors may contribute to the differences. We investigated the cytokine mRNA expressions, interleukin-2 (IL-2), IL-6, IL-10 and IFNr, on thioglycollate (TG) elicited-mouse peritoneal macrophages stimulated with various concentrations, 1 ng/ml, 10 ng/ml, 100 ng/ml, 1 ug/ml and 10 ug/ml, of LPS used by reverse transcription polymerase chain reaction (RT-PCR) and northern blot analysis. TG- elicited peritoneal macrophages expressed IL-6 and IFN-r mRNA in a dose-dependent manner. The expressions of IL-2 and IL-10 mRNA were dose-independent manner. In northern blot analysis, IL-6 mRNA expression was detected only in 10 ug/ml LPS concentration for short stimulation time (0.5 h), while IL-10 mRNAs were expressed evenly in all LPS concentrations. The expression of IL-6 mRNA was sustained until 72 h at 10 ug/ml concentration only, but IL- 10 mRNAs of all cases of LPS concentrations were sustained evenly until then. These results suggest that the concentration of LPS required for cytokine induction must be determined differently from gene to gene types, and although LPS concentration 10 ug/ml has not been used as an ordinary concentration in vitro cytokine study, 10 ug/ml of LPS might be more appropriate concentration in the study of IL-6 expression on mouse peritoneal macrophages.
Animals ; Blotting, Northern ; Chemokines ; Cytokines ; Gene Expression ; Interleukin-10 ; Interleukin-2 ; Interleukin-6 ; Macrophages, Peritoneal* ; Mice* ; Polymerase Chain Reaction ; Reverse Transcription ; RNA, Messenger*

Collet-Sicard syndrome is one of the syndromes of the multiple lower cranial nerve palsies, characterized by unilateral paralysis of 9th through 12th cranial nerves. The present report describes a 34-year-old woman who had hoarseness, dysarthria, and loss of taste developed after febrile illness. Brain MRI, both T1WI and T2WI, showed high signal intensity in the left jugular foramen. Gd-GTPA contrast injection revealed thickening and enhancement of the left tentorium. Angiography disclosed nonvisualization of the left transverse and sigmoid sinus, and reconstruction of the left internal and external jugular vein by collaterals from the angular, facial, and posterior fossa veins. The patient improved spontaneously two months later. This is the first report of Collet-Sicard syndrome resulting from jugular vein thrombosis.
Adult ; Angiography ; Brain ; Colon, Sigmoid ; Cranial Nerve Diseases ; Cranial Nerves ; Dysarthria ; Female ; Hoarseness ; Humans ; Jugular Veins* ; Magnetic Resonance Imaging ; Paralysis ; Thrombosis* ; Veins

A 65-year-old male received captoPnl therapy (25mg three times a day, for the treatment of congestive heart failure. Seven months after starting the captopril therapy he developed flaccid vesiculobullae and erythematous patches with oozing, crusted surfaces on his trunk and the proximal portion of his extremities. The mucous membranes were not involved. The mucous membranes were not involved.) The histopathologic findings showed subcorneal bulla containing a few acantholytic cells and direct immunofluorescent studies revealed intercellular deposition of IgG and C3 throughout entire epidermis, consistent with pemphigus foliaceus. After captopril therapy was discontinued, the skin lesions gradually improved within 1 month. Pemphigus foliaceus; is a rare complication of captopril therapy and this is, to our knowledge, the first case report in Korea.
Aged ; Captopril ; Epidermis ; Extremities ; Heart Failure ; Humans ; Immunoglobulin G ; Korea ; Male ; Mucous Membrane ; Pemphigus* ; Skin

No abstract available.
Female ; Obstetric Labor, Premature* ; Pregnancy ; Ritodrine*

We report a case of rhinocerebral mucormycosis in a 63-year-old female with a 1-year history of poorly controlled diabetes mellitus. She had black necrotic ulcers on the hard palate, bloody nasal discharge, swelling of the left side of her face, left blepharoptosis, proptosis, and conjunctival injection. Histopathological examination of the palatal lesion showed large, nonseptate, right-angled branching fungal hyphae in the dermis, and Rhizopus species was isolated on Sabouraud's agar media. The patient was treated with a combination of amphotericin B and surgical debridements but died of asphyxia one month after admission. This is a relatively uncommon, opportunistic infection occurring in a diabetic woman, and only several cases are reported in the Korean literature up to date.
Agar ; Amphotericin B ; Asphyxia ; Blepharoptosis ; Debridement ; Dermis ; Diabetes Mellitus ; Exophthalmos ; Female ; Humans ; Hyphae ; Middle Aged ; Mucormycosis* ; Opportunistic Infections ; Palate, Hard ; Rhizopus ; Ulcer

No abstract available.
Colitis, Ulcerative* ; Sweet Syndrome* ; Ulcer*

No abstract available.
Papilloma*

PURPOSE: This study investigates nurses' organizational commitment, internal marketing, and occupational satisfaction depending on their age, martial status, clinical experience and income. METHODS: The subjects of this study were 350 nurses from six hospitals in Jeolla-do. The t-tests were used to analyze the differences in internal marketing, occupational satisfaction, and organizational commitment depending on their age, marital status, career, and income. The relationships among internal marketing, occupational satisfaction, and organizational commitment were analyzed by the path analysis. RESULTS: The results of this study showed that organizational commitment was correlated with age, clinical experiences, and income, but not significantly associated with martial status. Education and training policy, benefit system, and fairness of the internal marketing were influencing factors on occupational satisfaction. These factors were correlated with organizational commitment through occupational satisfaction. CONCLUSION: This study addressed the relationships among nurses' internal marketing, occupational satisfaction, and organizational commitment. Based on the results, it is suggested that hospital organizations introduce more diverse incentive policies to enhance nurses' occupational satisfaction and organizational commitment.
Marital Status ; Marketing ; Motivation

We describe a 23-year-old man showing typically clinical and histological features of targetoid hemosiderotic hemangioma. About 35 cases of this newly-described entity have been reported since the first description by Santa Cruz and Aronherg in 1988. It is important to distinguish these tumors from patch stage Kaposi's sarcoma, retiform hemangioendothelioma and progressive lymphangioma.
Hemangioendothelioma ; Hemangioma* ; Humans ; Lymphangioma ; Sarcoma, Kaposi ; Young Adult