Normal albino rats weighing 180-200 gm were used for a series of this investigation on change of skin mast cell under general and local anesthesia. At first, left side abdominal skin was prepared by hair cutting with scissors about 3cm square and eight irritations by mean of biting with tip of forceps mosquito were applied along the prepared skin margin. Skin specimens were submitted from central area which surrounded by irritated points and also from intact contra-lateral area in 15, 30, 60 and l20 minutes invervals. Submiitted skin specimens were fixed in 10% formalin solution, then were stained with 1% toluidine blue. The number of mast cell was counted under 450X of microscopic examination. CONCLUSION l. There were two stages in changes of skin tissue mast cell number on normal saline solution injected area and irritated area by mean of biting with tip of forceps without any types of anesthesia. i) Decreasing stage: Number of skin tissue mast cell was decreascd and reached to the lowest level at 30 minutes after each irritation. ii) Increasing stage: Number of skin tissue mast cell was increased to the highest level at 120 minutes after each irritation. 2. General ether anesthesia could not infIuence on the change of mast cell number after mechanical biting irritation. 3, Local anesthesia with 2% procaine hydrochloride solution revealed slightly suppressing effect to increasing number of mast cell at 60 and 120 minutes after mechanical irritation. Hnwever, it was not evidence at 15 and 30 minutes after mechanical irritation. 4. There was no significant change of rnast cell number in the intact contralateraI skin area within 120 minutes under gencral and local anesthesia. 5. The number of degranulated mast cells did not correlated with counted total number of mast cells.
Anesthesia ; Anesthesia, Local ; Animals ; Cell Count ; Culicidae ; Ether ; Formaldehyde ; Hair ; Mast Cells* ; Procaine ; Rats ; Skin ; Sodium Chloride ; Surgical Instruments ; Tolonium Chloride

We preset a rare case of traumatic rupture of the iliacus muscle associated with paralysis of the femoral nerve. It occurred in a healthy 17 year old boy immediately after a fall on his back during the Taekwondo practice. The clinical picture is characterized by pain in the groin, a tender mass in the iliac fossa, flexion contracture of the hip, and a complete paralysis of the ipsilateral femoral nerve. This condition rarely occurs in individuals without bleeding tendency
Contracture ; Femoral Nerve ; Groin ; Hemorrhage ; Hip ; Humans ; Male ; Paralysis ; Rupture

Pancreatic pseudocyst occurs as a complication of pancreatitis or trauma, which results in the escape of pancreatic enzymes from the parenchyma or ductal system of pancreas. At that time, serum amylase may have returned to normal level, and the patient may be subjectively asymptomatic. In this phase, the radiologic findings are relatively greater significance than laboratory data. In the conventional radiologic study, pancreatic pseudocyst have been frequently confused with other retroperitoneal mass, but recently with clinical application of ultrasound and CT scan, more accurate diagnosis can be obtained. The brief results are as follows; 1. Male to female ratio was 3:2 in 15 patients. Incidence was most common in young adult age. Most frequent symptom was epigastic pain, and which was noted in 11 cases of patients. 7 cases of patients had past history of abdominal trauma and past history of pancreatitis was only in 1 case. Most common laboratory finding was leukocytosis in 8cases of patients and elevated serum amylase was also noted in 7 cases. 2. In each 5 cases of patients, plain chest roentgenologic evidence of left side pleural effusion and hemidiaphragm elevation were observed. 3. On flat abdomen film, soft mass shadow was visualized in 8 cases of patients. On UGI series, evidence of retrogastric space widening was observed in 11 cases of patients. 4. The location of pseudocyst is mainly in body and tail of pancrease in 11 cases of patients. 5. More accruable diagnosis can be obtained through application of ultrasound and CT scan.
Abdomen ; Amylases ; Diagnosis ; Female ; Humans ; Incidence ; Leukocytosis ; Male ; Pancreas ; Pancreatic Pseudocyst ; Pancreatitis ; Pancrelipase ; Pleural Effusion ; Tail ; Thorax ; Tomography, X-Ray Computed ; Ultrasonography ; United Nations ; Young Adult

From March 1985 to Sep.1985, Transcatheter hepatic arterial embolization was perfromed in 17 primary heptomaand 8 metstasis of liver in Department of Radiology, Yonsei University College of Medicine. Metastatic cancers ofliver were one nasopharyngeal cancer, one small bowel leiomyosarcoma, one gall bladder cancer and 5 colon cancers.The used embolization materials were the followings: Gelfoam particles for one primary hepatoma, 95% absoluteethanol for 4 patients, Ivalon(250-590micro m) for 19 patients and autologous blood clots for one metastasis, Theresults were summarized as the follows: 1. The devascularization of tumor vessels in post-emblization hepaticangiogram was complete in 6 primary hepatom and one metastasis and partial in 11 primary hepatoma and 7metastasis. 2. In the follow-up CT evaluation 3 to 4 weeks after embolization, well necrotic density was revealedin 8 primary hepatoma and one metastasis. 3. The complications were fever with higher than 38 degrees C(92%),abdominal pain (72%) and nausia or vomiting(40%). They were subsided wtihin one to 7 days after embolization. 4.In liver function study, sGOT and sGPT were elevated in 80% of total cases and returned to normal within 15 to 30days. LDH was variable. In 4 cases of absolute ethanol infusion, above liver enzymes were markedly elvated as 10times or more as normal range.
Alanine Transaminase ; Aspartate Aminotransferases ; Carcinoma, Hepatocellular ; Colon ; Ethanol ; Fever ; Follow-Up Studies ; Gallbladder Neoplasms ; Gelatin Sponge, Absorbable ; Hepatic Artery ; Humans ; Leiomyosarcoma ; Liver Neoplasms ; Liver ; Nasopharyngeal Neoplasms ; Neoplasm Metastasis ; Reference Values

Out of 75 patients who were admitted to our hospital because of abdominal trauma and were undergone theprocedures such as ultrasonography and/or CT scan within 24 hours of abdominal trauma due to suspected abdominalorgan injury. We analyzed the results of 38 patients who were confiremd of diagnosis by operation, follow-up CTscan or ultrasonography. 1. In the abdominal organ injury, solid organ injury consists of 8 cases of spleenlaceration, 1 of splenic subcapsular hematoma, 7 of hepatic laceration, 7 of pancreas laceration, 3 of renallaceration, and 3 of subcapsular hematoma of kidney. 2. In addition, there were 7 bowel and/or mesentericlaceration, 2 diaphragmatic hernia, and 1 urethral rupture. 3. 2 cases fo retroperitoneal hematoma and 1 case inwhich hemoperitoneum occurred without abdominal organ injury were confirmed by follow-up CT or ultrasonography. 4.In all of the 4 patients with multiple organ injury, pancreatic laceration was associated. 5. In abdominal traumapatients, ultrasonography or CT can be used to survey rapidly the entire abdomen for possible associated injury,and be of great help to clinicians in identifying the patients who need immediate surgery or in minimizing theincidence of unnecessary emergency abdominal exploration.
Abdomen ; Diagnosis ; Emergencies ; Follow-Up Studies ; Hematoma ; Hemoperitoneum ; Hernia, Diaphragmatic ; Humans ; Kidney ; Lacerations ; Pancreas ; Rupture ; Tomography, X-Ray Computed ; Ultrasonography

No abstract available.
Athletes* ; Forearm* ; Humans ; Magnetic Resonance Spectroscopy* ; Metabolism* ; Phosphorus*

No abstract available.
Carcinoma, Hepatocellular*

BACKGREOUND: Tetracaine has been the most commonly used spinal anesthetic agent. Recently bupivacaine has been found to be a useful agent, and has been reported not to cause neurologic complications as well as being a better quality anesthetic. The purpose of this study was to compare the anesthetic effects of bupivacaine with that of tetracaine. METHODS: Forty patients undergoing lower abdomen and lower limb operation were randomly allocated to two groups. Group I (n=20) received 15mg, 0.5% tetracaine in 10% dextrose, while Group II (n=20) received 15mg, 0.5% bupivacaine in 8% dextrose. After intrathecal injection of the agent at the level of L3-4 intervertebral space, the changes in sensory and motor block, blood pressure and heart rate were measured in two groups. RESULTS: The onset time of sensory block was more rapid in Group I than in Group II. Two segment regression time of sensory block was significantly longer in Group II than in Group I (p<0.05). The time for maximum motor block was shorter in group I than in Group II (p<0.05), but the duration of decreased motor block was significantly longer in Group I. The change of systolic blood pressure in Group II was less than the change in Group I. CONCLUSIONS: Bupivacaine has a longer sensory block duration, a weaker, shorter motor block duration and yields a less change in systolic blood pressure than tetracaine in spinal anesthesia.
Abdomen ; Anesthesia, Spinal* ; Anesthetics ; Blood Pressure ; Bupivacaine* ; Glucose ; Heart Rate ; Humans ; Injections, Spinal ; Lower Extremity ; Tetracaine*

Cervical pregnancy is a rare form of ectopic gestation in which the blastocyst implants in the cervical mucosa below the histologic cervical os. Because of the serious vaginal bleeding, hysterectomy was usually done in the management of cervical pregnancy. Howerver, conservative treatment is desirable for women who want to be pregnancy in the future. Methotrexate has been utilized recently for conservative management of cervical pregnancy. We report a case of cervical pregnancy which was treated succesfully with intramuscular methotrexate injection.
Blastocyst ; Female ; Humans ; Hysterectomy ; Methotrexate* ; Mucous Membrane ; Pregnancy* ; Uterine Hemorrhage

The distance fmm skin to the lumber epidural space was measured in 60 male patients receiving epidural analgesia. The mean distance was found to be 4.45cm. The epidural depths were identified most frequently at 4.0 to 4.5cm deep and over 90% of total cases were less than 5.5cm deep. The epidural depths had correlations with weight and PI(P < 0.001), but not correlated with height.
Adult* ; Analgesia, Epidural ; Epidural Space* ; Humans ; Male* ; Skin*