1.The Clinical Coures of Mild Neonatal Hydronephrosis.
Jong Ho PARK ; Young Tae LEE ; Jae Seop SHIN
Korean Journal of Urology 2000;41(7):872-877
No abstract available.
Hydronephrosis*
2.Two cases of nasopharyngeal carcinoma in children.
Tae Sun HA ; Chul Ho JANG ; Hee Young SHIN ; Hyo Seop AHN
Journal of the Korean Pediatric Society 1991;34(4):587-593
No abstract available.
Child*
;
Drug Therapy
;
Humans
;
Radiotherapy
3.A Metastatic Giant Cell Tumor of the Soft Tissue of the Thoracic Wall: A case report.
Duk Seop SHIN ; Tae Eun CHUNG ; Jang Hoon LEE ; Jun Hyuk CHOI
The Korean Journal of Thoracic and Cardiovascular Surgery 2007;40(7):526-528
A giant cell tumor of bone is a benign bone tumor, but has very high local recurrence rate and, very rarely metastasizes to the lung or a distant area. We report a case of a 29-year-old male patient presenting with a metastatic giant cell tumor of the soft tissue of the chest wall, who underwent a total resection of the radius for recurrence of the giant cell tumor. The tumor was not related to any bony structure of the thorax. We resected the tumor with a wide surgical margin. No evidence of malignancy was seen in the frozen and permanent pathological report.
Adult
;
Giant Cell Tumor of Bone
;
Giant Cell Tumors*
;
Giant Cells*
;
Humans
;
Lung
;
Male
;
Radius
;
Recurrence
;
Thoracic Wall*
;
Thorax
4.Herpes Zoster in Children with Malignancy.
Tae Heung KIM ; Kyung Chan PARK ; Jeong Aee KIM ; Seon Hoon KIM ; Yoo Shin LEE ; Hyo Seop AHN
Korean Journal of Dermatology 1990;28(4):441-444
We described the clinical manifestation of herpes zoster in thirteen children with underlying malignancies. Among the associated malignancies, hematologic malignancy including acute lymphotytic leukemia was the commonest and CNS tumors were also frequently associated. Pain was mild, and some showed high fever and abnormal liver function test results. Recurrent attacks were observed in 3 cases(23%). Thoracic segment and trigeminal nerve were commonly affected. In most cases, herpes zoster developed within two years after the diagnosis of the malignancy.
Child*
;
Diagnosis
;
Fever
;
Hematologic Neoplasms
;
Herpes Zoster*
;
Humans
;
Leukemia
;
Liver Function Tests
;
Trigeminal Nerve
5.A Case of Renal Cyst with Peripheral Thick Egg-shell Calcification.
Jae Seop SHIN ; Jae Woo KIM ; Young Tae LEE
Korean Journal of Urology 1989;30(2):235-238
Calcification is found in 4% to 12% of renal masses due to a number of causes and can be seen in various patterns. This is found in 1% to 3% of the simple renal cysts. Among these a peripheral egg-shell type of calcification is more rare. We experienced the simple renal cyst associated with the thick egg-shell calcification on the renal upper pole in a 66-year-old female complaining upper abdominal discomfort, so we report that with literature.
Aged
;
Female
;
Humans
6.Extracellular vesicles derived from small intestinal lamina propria reduce antigen-specific immune response
Tae-Seop SHIN ; Jae Yong PARK ; Yoon-Keun KIM ; Jae Gyu KIM
The Korean Journal of Internal Medicine 2022;37(1):85-95
Background/Aims:
Extracellular vesicles (EVs) are secreted from various types of cells and have specific functions related to their origin. EVs are observed in the small intestinal lamina propria (lpEVs), but their function remains unclear. This study aimed to investigate the role of lpEVs.
Methods:
LpEVs were isolated from antigen (ovalbumin [OVA])-fed mice (lpEVs/OVA), and administrated to the naïve mice for 5 days before induction of lung inflammation. Afterwards, the mice were sensitized and challenged with OVA to evaluate the role of lpEVs/OVA in the regulation of immune tolerance.
Results:
The isolated lpEVs/OVA were sphere-shaped, bi-layered vesicles of approximately 50 to 100 nm in size. The vesicles expressed CD81, A33 antigen, and major histocompatibility complex (MHC) class II on the surface. When administrated to naïve mice, the lpEVs/OVA migrated to the spleen. Intraperitoneal lpEVs/OVA administration to naïve mice decreased the immune response against sensitized antigen in a CD4+FoxP3+T cell-dependent manner.
Conclusions
EVs are actively secreted from small intestinal epithelial cells to deliver information about orally administered antigens to immune cells, which will facilitate the modulation of the immune response by acting as an intercellular communicasome.
7.Leiomyomas on the Bilateral Corpus Cavernosa of the Penis: A Case Report.
Sun Tae HWANG ; Chi Young PARK ; Sang Kuk YANG ; Jae Seop SHIN ; Hong Sup KIM ; Yong Soo LHO
Korean Journal of Urology 1995;36(5):584-586
Leiomyoma is a benign tumor, which usually occur at the smooth muscle of the gastrointestinal tract and uterus but rarely occurs on the corpus cavernosum of the penis. We experienced a patient with leiomyomas on the bilateral corpus cavernosa of the penis accompanied with impotence in a 60-year-old man. The patient was treated with complete local excision and has remained well without recurrence for l year, So we report this case with review of literatures.
Erectile Dysfunction
;
Gastrointestinal Tract
;
Humans
;
Leiomyoma*
;
Male
;
Middle Aged
;
Muscle, Smooth
;
Penis*
;
Recurrence
;
Uterus
8.A Case of Reconstruction of Abdominal Wall Defect using Tensor Fascia Lata Myocutaneous Flap: The Defect Caused by a Wide Resection of Squamous Cell Carcinoma of Bladder Invading Abdominal Wall.
Young Tae LEE ; Young Kwon HONG ; Jong Ho PARK ; Je Won KIM ; Jae Seop SHIN
Korean Journal of Urology 1999;40(6):795-798
Squamous cell carcinoma of bladder is best treated with a radical cystectomy. Squamous cell carcinoma of bladder invading the abdominal wall is not commonly reported and hard to manage surgically. Abdominal wall defect caused by a wide resection of squamous cell carcinoma invading abdominal wall can be reconstructed using various muscle flaps. We performed a salvage cystectomy for a patient with squamous cell carcinoma of bladder invading abdominal wall up to skin, and the abdominal wall defect was successfully reconstructed using a unilateral tensor fascia lata myocutaneous flap.
Abdominal Wall*
;
Carcinoma, Squamous Cell*
;
Cystectomy
;
Fascia Lata*
;
Fascia*
;
Humans
;
Myocutaneous Flap*
;
Skin
;
Urinary Bladder*
9.Treatment of Chronic Bacterial and Nonbacterial Prostatitis by Local Injection of Amikacin Sulfate.
Jong Ho PARK ; Young Tae LEE ; Young Kwon HONG ; Jae Seop SHIN
Korean Journal of Andrology 2000;18(1):63-67
PURPOSE: Prostatitis causes significant morbidity and represents a major indication for diagnostic procedures and treatment with antibiotics or other medications. Chronic bacterial prostatitis is effectively controlled by local injection of antibiotics and can be diagnosed by tissue culture. Also, chronic nonbacterial prostatitis often proves to be of bacterial origin by tissue culture. We introduced intraprostatic injection of antibiotic (amikacin sulfate) for chronic bacterial and nonbacterial prostatitis PATIENTS AND METHODS: From March 1996 to January 1998, we treated 42 patients complaining of prostatitis symptoms and showing >10 leukocytes/high-power field in expressed prostatic secretions (EPS). All patients had suffered prostatitis for more than 6 months and had histories of use of medications. Eight patients proved to have bacterial prostatitis and 34 patients nonbacterial prostatitis. We injected 500 mg of amikacin sulfate via the transperineal approach under the guidance of transrectal ultrasonography. RESULTS: Of the 42 patients, 27 (64%) improved symptomatically and showed normal EPS finding. Twenty-two patients (65%) in the nonbacterial prostatitis group and 5 patients (63%) in the bacterial prostatitis group were cured, with 23 patients (85%) requiring only one or two intraprostatic injections to obtain the cure. Complications occurred during and after the procedure in eight patients: severe pain, hemospermia, gross hematuria, and dysuria. CONCLUSIONS: Intraprostatic injection of amikacin sulfate is an alternative treatment for chronic bacterial and nonbacterial prostatitis. The advantage of this therapy is that it provides high concentration of the antibiotic at the infection focus without any risk of metabolic activation.
Amikacin*
;
Anti-Bacterial Agents
;
Biotransformation
;
Dysuria
;
Hematuria
;
Hemospermia
;
Humans
;
Prostatitis*
;
Ultrasonography
10.Two Cases of Duane's Retraction Syndrome.
Yong Ja HWANG ; Ki Ryong KIM ; Byoung Ho KIM ; Dong Min SHIN ; Wan Seop SHIM
Journal of the Korean Ophthalmological Society 1979;20(3):379-383
Duane's retraction syndrome is a deficiency in abduction and a defect in abduction movements, with retraction and narrowing of the palpebral fissure of the affected eye. In addition, there are often an upshoot or downshoot of the affected eye on attempted abduction, widening of the palpebral fissure with abduction and mild to marked defect in convergence. But, the clinical picture in Duane's retraction syndrome is extremely variable. Two cases of Duane's retraction syndrome are presented, each of them is Duane's type I and type III, which are affected on left eye. The literatures relating to this syndrome are briefly reviewed.
Duane Retraction Syndrome*