1.Sugical treatment of stage IV gastric cancer.
Journal of the Korean Cancer Association 1993;25(3):343-349
No abstract available.
Stomach Neoplasms*
2.Depression of highschool senior students in Seoul.
Min Chang LEE ; Mi Kyung OH ; Jong Tae CHOI
Journal of the Korean Academy of Family Medicine 1992;13(12):927-934
No abstract available.
Depression*
;
Humans
;
Seoul*
3.Malignant Lymphoma of Mucosa-associated Lymphoid Tissue Arising in the Conjunctiva.
Tae Kyung KIM ; Jang Oh KIM ; Sang Won KIM ; Hoon Kyu OH ; Jae Bok PARK
Annals of Dermatology 1995;7(3):273-277
We report two cases of malignant lymphoma of mucosa-associated lymphoid tissue arising in the conjunctiva. Case 1, an 18-year-old girl, showed her left lower conjunctival swelling for four months and Case 2, a 29-year-old man, showed similar lesions on both his eyes for one year. Histologically, both cases revealed monomorphous dense lymphoid infiltrates invading the overlying conjunctival epithelium with diffuse patterns. The infiltrates were composed of small lymphocytes admixed with centrocyte-like cells within the conjunctival epithelium and stroma in association with B-cell lineage. No relapse was noted during the period of about 1½ years follow-up in case 1 treated by local excision only and in the follow-up period of 2 months in case 2 treated by local excision and subsequent chemotherapy.
Adolescent
;
Adult
;
B-Lymphocytes
;
Conjunctiva*
;
Drug Therapy
;
Epithelium
;
Female
;
Follow-Up Studies
;
Humans
;
Lymphocytes
;
Lymphoid Tissue*
;
Lymphoma*
;
Recurrence
4.A Study on the Role of Bacteria in the Pathogenesis of Confluent and Reticulated Papillomatosis.
Hyun Tae LEE ; Tae Ahn CHUNG ; Kyung Sool KWON ; Ho Sun JANG ; Chang Keun OH
Korean Journal of Dermatology 1998;36(1):78-85
BACKGROUND: The pathogenesis of confluent and reticulated papillomatosis(CRP) is still unknown, although many theories have been suggested. It is stressed that abnormal host response to colonization of pityrosporum orbiculare might play a role in the pathogenesis of CRP, but is not completely understood. Frequently, we have observed bacterial colonies in the stratum corneum and, especially, within the hair follicles from biopsy specimens of patients with CRP. In addition, successful treatment for CRP with minocycline, a derivative of tetracyclines, has been reported continuously. OBJECTIVE: The purpose of this study was to document the possible association of bacterial factors in the pathogenesis of CRP and to elucidate the effectiveness of minocycline. METHODS: We performed Brown and Brenn gram staining in 12 biopsy specimens, bacterial cultures, identification of microorganisms and antibiotics sensitivity testing including minocycline. We administered oral minocycline with an initial dose of 100mg per day for 1 to 3 months and a maintenance dose 50mg per day for I to 2 months, then evaluated the response of treatment. RESULTS: 1. On Brown and Brenn staining, the gram positive bacterial colonies that stained dark bluish or nearly black were observed within the infundibulum of hair follicles in 10 out of 12 biopsy specimens(83.3%) and on the keratotic invagination of stratum corneum in 11 out of 12 biopsy specimens(91.7%). 2. Histological features of regions where bacterial colonies were observed showed, hyperkeratosis and keratotic invagination on the stratum corneum in all cases. Hyperkeratosis(66.7%), parakeratosis(16.7%), inflammatory cell infiltration(25.0%), perifollicular fibrosis(33.3%), and abnormal keratin in sebaceous ducts(50.0%) were shown in hair follicles. 3. In anaerobic cultures, no bacteria was grown. In aerobic cultures, staphylococcus species were identified in 6 cases, streptococcus viridans in one case, sternotrophomonas maltophilia in one case. In the susceptibiliity test, minocycline was sensitive in 7 from 8 cases. 4. The therapeutic response to minocycline was observed within one month in all cases, and the time to clear the lesions was 1/2 month in 2 cases, 1 month in 4 cases, 2 months in 5 cases, 3 months in one case, respectively. CONCLUSION: Form these results, we suggest that bacterial factors may play an important role in the pathogenesis of CRP and that the action mechanism of minocycline in the treatment of CRP may be due to antibacterial effects.
Anti-Bacterial Agents
;
Bacteria*
;
Biopsy
;
Colon
;
Hair Follicle
;
Humans
;
Malassezia
;
Minocycline
;
Papilloma*
;
Staphylococcus
;
Tetracyclines
;
Viridans Streptococci
5.Neonatal gastric perforation with diaphragmatic eventration: a case report.
Yeon Im LEE ; Sung Tae OH ; Kyung Kuk KIM ; Kyung Rae KIM ; Yong Kak LEE
Journal of the Korean Surgical Society 1993;45(1):140-145
No abstract available.
Diaphragmatic Eventration*
6.Primary adenocarcinoma of the appendix.
Seong Choon KANG ; Kyung Rae KIM ; Kyung Kook KIM ; Sung Tae OH ; Young Chae CHU
Journal of the Korean Society of Coloproctology 1992;8(3):319-325
No abstract available.
Adenocarcinoma*
;
Appendix*
7.Synchronous multiple gastric cancer: triple cancer.
Sung Tae OH ; Kyung Kuk KIM ; Kyung Rae KIM ; Yong Wha MOON
Journal of the Korean Surgical Society 1992;42(2):262-266
No abstract available.
Stomach Neoplasms*
8.Synchronous multiple gastric cancer: triple cancer.
Sung Tae OH ; Kyung Kuk KIM ; Kyung Rae KIM ; Yong Wha MOON
Journal of the Korean Surgical Society 1992;42(2):262-266
No abstract available.
Stomach Neoplasms*
9.Ultrasonographic diagnosis in acute appendicitis.
Hyeong Sur JEONG ; Kyung Rae KIM ; Sung Tae OH ; Kyung Kuk KIM
Journal of the Korean Surgical Society 1992;42(1):114-119
No abstract available.
Appendicitis*
;
Diagnosis*
10.Expression of Several Cell Cycle Regulatory Genes in Cultured AT-1 Cardiomyocytes after Formation of Synchronously Beating Sheets.
Kyung Keun KIM ; Chang Weon OH ; Kook Heon SEO ; Jeong Tae KOH
Korean Circulation Journal 1998;28(4):611-619
BACKGROUND AND OBJECTIVE: AT-1 cells have been derived from the left atrial tissue in which the ANF promoter targeted SV40 large T antigen expression. When cultured, clusters of spontaneously contracting cells were observed after 4-5 days and contiguous sheets of synchronously beating cardiomyocytes were formed after 10 days. In this study, expression of several cell cycle regulatory genes were monitored through Northern blot analyses in AT-1 cells during beating and after formation of beating sheets (BS). MATERIALS AND METHOD: AT-1 RNAs were obtained in 3 days after plating, during beating and after formation of BS, and used for Northern blot analyses. RESULTS: alpha-Cardiac myosin heavy chain expression was prominent in beating cells, as would be expected for this contractile protein isoform but ANF was decreased after beating. Gax was not expressed in cultured AT-1 cells but in AT-1 tumor and murine heart. p53 and p21 were decreased after beating which indicate transcription level of p53 and p21 correlated well in AT-1 cells. In contrast, pRB and p107 were increased after beating but p68 (2.4 kb) which arose by alternative splicing of p107 and lacks the pocket domain B was decreased in beating cells. pTCS2, murine tuberous sclerosis gene, represented similar levels during beating but a little was decreased after formation of BS. mRAD50, the murine homologue of yeast DNA recombinational repair gene RAD50, was increased in beating cells, a similar pattern to p107 and pRB. But the p50 arose by alternative splicing of mRAD50 and has 3' half of mRAD50 had unexpectedly appeared and maintained after beating. CONCLUSION: The expression of cell cycle regulatory genes after beating and formation of BS in AT-1 cells showed gene-specific pattern and the p50 which has homology to the mRAD50 may participate in differentiation of cardiomyocytes.
Alternative Splicing
;
Antigens, Viral, Tumor
;
Atrial Natriuretic Factor
;
Blotting, Northern
;
Cell Cycle*
;
Genes, Regulator*
;
Heart
;
Myocytes, Cardiac*
;
Myosin Heavy Chains
;
Recombinational DNA Repair
;
RNA
;
Tuberous Sclerosis
;
Yeasts