1.Mucous Gland Adenoma of the Bronchus: A case report.
Sook Tae HA ; Kang Suek SUH ; Sun Kyung LEE
Korean Journal of Pathology 1986;20(2):226-228
A case of mucous gland adenoma arising from the main bronchus of the middle lobe of the right lung is reported, with review of related literatures. The patient, a 12 year-old Korean male, was admitted to Pusan National University Hospital with complaints of progressive coughing and dyspnea. Roentgenographic studies revealed a well defined mass involving the right middle lobe of the lung. With the impression of benign tumor, right middle lobectomy was performed. The gross specimen revealed a polypoid mass involving the main bronchus, measuring 4.5x 3.7 x 2.5cm. The cut surface of the mass revealed yellow-gray myxoid tissue. Histologically, the mass consisted of glandular structures filled with mucus, which proved to be acid one on histochemical study. The glandular lining was made up of a single layer of berign mucous cells, many of them being flattened.
Adenoma
2.A Case of Neuroblastoma Originated from Mediastinum.
Suh Hong HA ; Won Kyung KIM ; Kyung Tae KIM ; Jung Hee LEE
Journal of the Korean Pediatric Society 1985;28(7):714-719
No abstract available.
Mediastinum*
;
Neuroblastoma*
3.Animal Experimentation for Bariatric Surgery.
Journal of Metabolic and Bariatric Surgery 2017;6(2):25-29
Bariatric surgery is considered the most effective treatment for reducing and maintaining weight for morbid obesity. Moreover, this surgery not only reduces weight but also improves comorbidity. However, concern about the safety of the surgery has grown with the favorable effects and has been heightened by high-profile reports in the death of a famous singer after bariatric surgery in Korea. In the beginning of the era of bariatric surgery, animal experiments had been conducted to improve surgical techniques in bariatric surgery. Among animals, a large animal such as pig and rabbit was used to develop and assess surgical skill. Recently, many researchers have been trying to investigate the mechanism of bariatric surgery for the resolution of morbid obesity and related comorbidities. An experimental model employing small animal has been developed to study underlying mechanism. We expect that this experiment will pave the way for developing a novel morbid obesity treatment.
Animal Experimentation*
;
Animals*
;
Bariatric Surgery*
;
Comorbidity
;
Korea
;
Models, Theoretical
;
Obesity, Morbid
;
Singing
4.Can Bariatric Surgery Be a Surgical Treatment to Prevent the Progression of Chronic Kidney Disease?.
Journal of Metabolic and Bariatric Surgery 2016;5(1):28-35
Obesity is a serious worldwide health problem causing numerous obesity-related comorbidities such as hyperlipidemia, hypertension, diabetes, and cardiovascular dysfunctions. Recently, many studies indicate that obesity is strongly related with high rate of renal lesions and reducing weight with surgical intervention can improve renal parameters in obese patients, but the effect of bariatric surgery on obesity-induced chronic kidney disease (CKD) is hardly documented. This review study shows that bariatric surgery demonstrates beneficial reduction in proteinuria and albuminuria leading to improve both glomerular hyperfiltration and chronic kidney disease in obese population. Yet, bariatric surgery is not a definite treatment of choice for the obese patients with CKD because of lack of evidence explaining the risk of complications following bariatric surgery and clarification on estimating glomerular filtration rate (eGFR) in obese patients. Future, high quality studies with a long term follow up are required to determine the effective durability of bariatric surgery on obese-related CKD patients.
Albuminuria
;
Bariatric Surgery*
;
Comorbidity
;
Follow-Up Studies
;
Glomerular Filtration Rate
;
Humans
;
Hyperlipidemias
;
Hypertension
;
Obesity
;
Proteinuria
;
Renal Insufficiency, Chronic*
5.Granulomatous Mycosis Fungoides: A case report.
Kyung Sin LEE ; Young Oak KIM ; Kee Suck SUH ; Sang Tae KIM ; Man Ha HUH
Korean Journal of Pathology 1995;29(5):694-697
Granulomatous mycosis fungoides is an extremely rare and unusual histologic variant of mycosis fungoides. This form is clinically characterized by spontaneous resolution of ulcerated nodular lesions into poikiloderma. Histologically, a strong granulomatous component can obscure the underlying cutaneous lymphoma, which is frequently mistaken for non-neoplastic dermatitides or cutaneous sarcoidosis. We report a case of granulomatous mycosis fungoides occurring on the left cheek of 34-year-old man confirmed histologically with an aid of immunohistochemistry and clinical course (immediate response to PROMACE-CYTOBAM chemotherapy), with emphasis on differential diagnosis, along with a review of literature. This is the first documented report in the Korean literature.
Male
;
Humans
;
Diagnosis, Differential
6.Malignant Histiocytosis: A case report.
Sook Tae HA ; Gi Yeong HUH ; Kang Suek SUH ; Sun Kyung LEE
Korean Journal of Pathology 1986;20(3):395-398
We have recently experienced a clinically atypical case of malignant histiocytosis involving the spleen, ileum and bone marrow, in a 25-year-old Korean male. He was admitted to our hospital because of multiple purpuric lesions of skin which had been appearing since 2 years ago. Physical and laboratory examinations revealed marked splenomegaly with pancytopenia. With clinical impression of hypersplenism, splenectomy was performed. During the operation, the surgeons found a dark red mucosal lesion in the ileum incidentally, to resect the segment. Microscopic findings of the spleen and the ileal lesion showed extensive proliferation of atypical histiocytes, many of them phagocytosing numerous erythrocytes. Bone marrow biopsy was done for follow-up study, which showed increased cellularity with infiltration of atypical histiocytes.
Follow-Up Studies
;
Biopsy
7.Clinical Importance of the Resection Margin Distance in Gastric Cancer Patients.
Journal of the Korean Gastric Cancer Association 2006;6(4):277-283
PURPOSE: The way in which the resection margin distance for gastric cancer patients who undergo a gastric resection influences the recurrence rate, aspects of recurrence, and the prognosis according to the characteristic of the tumor is not known. We aim to find a standard for tailor-made treatment after selecting patients in this point of view who need a more sufficient resection margin. MATERIALS AND METHODS: A retrospective study was done on 1,472 patients who underwent a gastrectomy due to gastric cancer at our hospital from 1992 to 2005. The median follow-up period was 37 months. RESULTS: There were no significant differences in the recurrence rate, the aspects of recurrence, and the 5-year survival rate between early gastric cancer (EGC) patients with a resection margin distance of less than 2 cm compared with EGC patients with a resection margin distance of greater than 2 cm. However, significant differences in the survival rate were found in advanced gastric cancer (AGC) patients when the patients were classified into groups with resection margin distances less than or greater than 3 cm (P=0.02). Significant differences were noted especially in cases of diffuse histologic-type tumors located in the lower third of the stomach and in cases with Borrmann type-3 and -4 tumors. CONCLUSION: The distance between the tumor resection margin and the proximal gastric resection margin has no significant influence on the survival rate in EGC patients if the resection margin is negative. However, to improve a patient's survival rate, it is important to guarantee a resection margin of more than 3 cm in AGC patients, especially when the tumor is a diffuse histologic type located in the lower third of the stomach or a Borrmann type 3 and 4.
Follow-Up Studies
;
Gastrectomy
;
Humans
;
Prognosis
;
Recurrence
;
Retrospective Studies
;
Stomach
;
Stomach Neoplasms*
;
Survival Rate
8.SIADH Caused by the Synergistic Effect of S-1 and Thiazide.
Journal of the Korean Gastric Cancer Association 2006;6(3):198-201
Hyponatremia is a dangerous electrolyte disturbance in patients on chemotherapy and may cause sudden death if not detected early. SIADH (syndrome of inappropriate antidiuretic hormone) is one of the known causes of hyponatremia in patients undergoing chemotherapy. Few chemotherapeutic agents, however, are reported to cause SIADH. The current study reports that SIADH developed in a 55 year old woman on S-1 (80 mg/m2) and cisplatin (60 mg/m2) chemotherapy for the peritoneal metastasis of gastric cancer. The patient underwent a total gastrectomy, a splenectomy, and a segmental resection of the transverse colon for gastric cancer. She had used thiazide and betablocker to treat hypertension for 12 years. She admitted to our hospital with complaining of general weakness, dysarthria, loss of appetite, and urinary discomfort. The serum level of sodium and potassium were 94 mEq/L and 2.2 mEq/L respectively. The hyponatremia completely resolved uneventfully after 3% saline infusion, which led to normalized electrolyte balance. The patient was discharged on the 13th hospital day.
Appetite
;
Cisplatin
;
Colon, Transverse
;
Death, Sudden
;
Drug Therapy
;
Dysarthria
;
Female
;
Gastrectomy
;
Humans
;
Hypertension
;
Hyponatremia
;
Inappropriate ADH Syndrome*
;
Middle Aged
;
Neoplasm Metastasis
;
Potassium
;
Sodium
;
Splenectomy
;
Stomach Neoplasms
;
Water-Electrolyte Balance
9.Subclassification of Stage IV Gastric Cancer According to the Presence of Distant Metastasis (IVa and IVb).
Journal of the Korean Gastric Cancer Association 2006;6(3):173-180
PURPOSE: The TNM staging system showed limitation in stratifying patients into different prognostic groups with gastric cancer. Since the treatment for stage IV gastric cancer with distant metastasis (M1) is defined as non-curative one, we hypothesized that the survival rate of stage IV gastric cancer with M1 is different to that of stage IV gastric cancer with no distant metastasis (M0), which will provide a rationale to subdivide stage IV into IVa and IVb. MATERIALS AND METHODS: From June 1992 to December 2005, of 1,630 gastric cancer patients who underwent surgery, 308 patients with stage IV gastric cancer were selected and analyzed. The clinicopathologic characteristics and survival of the patients, according to distant metastasis, were determined retrospectively. Median follow-up period was 13 months (range: 1~154 month). RESULTS: 5 year survival rate of M0 and M1 group was 35% and 16% respectively with statistic significance (P=0.0000). When the survival rate of M0 group was analyzed according to the difference of T and M factor, T1-3N3M0 and T4N1-2M0 group showed no significant statistical difference (P=0.1898). CONCLUSION: Given the result in this study, we suggest that the stage IV gastric cancer be subclassified into stage IVa and IVb according to M factor.
Follow-Up Studies
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Humans
;
Neoplasm Metastasis*
;
Neoplasm Staging
;
Retrospective Studies
;
Stomach Neoplasms*
;
Survival Rate
10.A Case of Overlapping Syndrome of Primary Membranous Nephropathy and IgA Nephropathy.
Tae Seog KIM ; Mi Kyung CHA ; Jong Ho LEE ; Seung Yeon HA
Korean Journal of Nephrology 1998;17(4):624-628
We report a rare case of primary glomerular disease with both features of IgA nephropathy and membranous glomerulonephritis in a 27 year-old woman with nephrotic syndrome. Histologically, glomeruli showed slight mesangial expansion, proliferation of mesangial cells, and short subepithelial spikes on capillary wall. Direct immunofluorescence demonstrated granular IgG and C3 deposits along the capillary walls, and IgA with C3 deposits in mesangium. Granular subepithelial and rnesangial deposits were observed by electron microscopy. The patient showed complete remission after 6 months therapy with steroid and ACE inhibitor.
Adult
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Capillaries
;
Female
;
Fluorescent Antibody Technique, Direct
;
Glomerulonephritis, IGA*
;
Glomerulonephritis, Membranous*
;
Humans
;
Immunoglobulin A*
;
Immunoglobulin G
;
Mesangial Cells
;
Microscopy, Electron
;
Nephrotic Syndrome