Influence of acute and chronic carbon monoxide poisoning on the rat prostate has been studied enzymologically and the following results were obtained: 1. An increasing tendency of the total lactate dehydrogenase activity in the prostate tissue was observed is the chronic poisoning groups. 2. The lactate dehydrogenase isoenzyme distribution pattern was not remarkably influenced by chronic poisoning. 3. The lactate dehydrogenase isoenzyme distribution pattern is the prostate tissue was as LDH5> LDH4> LDH3> LDH2> LDH1.
Animals ; Carbon Monoxide Poisoning* ; Carbon Monoxide* ; Carbon* ; L-Lactate Dehydrogenase* ; Lactic Acid* ; Poisoning ; Prostate* ; Rats*

Influence of acute and chronic carbon monoxide poisoning on the rat testis has been studied enzymologically and the following results were obtained: Experimental animals were divided as 1) control, C1 (6 animals) 2) acute poisoning with 0.5% carbon monoxide until death, C2 (10 animals) 3) chronic poisoning with 0.05% carbon monoxide for 2 hours daily E1 (5 animals)...3 days/week for 8 weeks E2 (6 animals)...3 days/week for 4 weeks 4) acute poisoning until death with 0.5% carbon monoxide after chronic poisoning with 0.05% carbon monoxide E3 (5 animals)...chronic poisoning for 8 weeks plus acute poisoning E4 (5 animals)...chronic poisoning for 4 weeks plus acute poisoningUsing Neiland's method, the total activities and distribution patterns of lactic dehydrogenase in rat testis were measured. All of the data were analyzed statistically. 1. The total activities of lactic acid dehydrogenase in all experimental groups seemed to increase. In the group E3, the increase was statistically significant.(p<0.05) 2. No significant changes were observed in the lactic acid dehydrogenase isoenzyme distribution pattern of the testis. both is the control and experimental groups. 3. The lactic acid dehydrogenase distribution patterns were as fraction l>2>4>3>5 4. No significant histopathological changes were observed in the rat testis.
Animals ; Carbon Monoxide Poisoning* ; Carbon Monoxide* ; Carbon* ; L-Lactate Dehydrogenase* ; Lactic Acid* ; Oxidoreductases ; Poisoning ; Rats* ; Testis*

No abstract available.
Aged, 80 and over* ; Humans ; Transurethral Resection of Prostate*

Elephantiasis neuromatosa is one of 3 types of cutaneous tumors in Von Recklinghausen's disease. This 28 year-old male patient visited for adult-fist sized tumor associated with hairy pigmented patch on right antecubital fossa, and various sized tumors and cafe-au-lait spots on whole body of about 27 years duration. Past history was noncontributory. Family history revealed that his father and son had similar manifestations. Laboratory findings were noncontributory. Histopathology of cafe-au-lait spot and hairy pigmented patch revealed increase of melain in basal cell layer of the epidermis and increase in the concentratiton and activity of the melanocytes in basal cell layer of the epidermis. Histopathology of the mass revealed slightly thin, wavy fibrs lying in loosely textured strands extending in varying directions and a fairly large number of nuclei that are ovel to spindle-shaped and fairly uniform in size.
Adult ; Cafe-au-Lait Spots ; Deception ; Elephantiasis* ; Epidermis ; Fathers ; Humans ; Male ; Melanocytes ; Neurofibromatosis 1

No abstract available.
Humans* ; Saponins* ; Skin*

A 32-year-old male patient with uncontrolled diabetes mellitus was affected with hyperlipoproteinemia type II His skin lesion showed yellowish papulsr tuberoruptive xanthoma on forearm, shoulder, elbow and knee. Besides skin eruption, he showed abnormal liver function test and right bundle branch block on EKG. The laboratory examinations revealed increase of serum cholesterol, triglycerides. and fasting blood sugar, and slight turbid color of fasting blood serum which had been kept standing at 4C for 24 hrs. On the agarose electrophoresis, bands of different densities of LDL and VLDL in beta and pre-beta position Were noted. Authors discussed here about laboratory characteristics, clinical manifestations and differential diagnosis of hyperlipoproteinemia type II and III.
Adult ; Blood Glucose ; Bundle-Branch Block ; Cholesterol ; Diabetes Mellitus* ; Diagnosis, Differential ; Elbow ; Electrocardiography ; Electrophoresis ; Fasting ; Forearm ; Humans ; Hyperlipoproteinemia Type II* ; Hyperlipoproteinemias* ; Knee ; Liver Function Tests ; Male ; Sepharose ; Serum ; Shoulder ; Skin ; Triglycerides ; Xanthomatosis

The statistical study of new outpatients of skin problems seen in dermatologic department of Seoul Red Cross Hospital from l976 to 1980 was done and the 10 most common dermatoses were analysed in detail, The results were summarized as follows: 1) Of 19,679 outpatients, males were 10,530(53.5%) and females were 9,149(46.5%). The sex ratio of male to female was 1. 15: l. 2) The most common dermatoses were atopic dermatitis/eczema(16. 9%), fungal infection(16. 2%), contact dermatitis(15. 3%), scabies(10. 7%), urticaria(10. 6%), acne(9. 5%), pyoderma(8. 3%), insect bite(5. 6%), syphilis(4. 1%) and psoriasia (2. 8%). 3) Of 10 most common dermatoses, contact dermatitis, acne, scabies and urticaria were revealed to have a tendency to increase year by year, syphilis and psoriasis were constant pattern and other common dermatoses showed irregular pattern in their incidence. 4) The sex ratio of male to female of l0 most common dermatoses was l. 23: l. Fungal infection, scabies, pyoderma, insect bite, syphilis and psoriasis wereoutnumbered in male and atopic dermatitis/eczema, contact dermatitis, urticaria and acne were outnumbered in female. 5) Atopic dermatitis/eczema & scabies were prevalent in winter, acne, fungal infection, urticaria and pyoderma in summer, and contact dermatitis in spring and summer. 6) The most frequent age groups of atopic dermatitis/eczema were 1 to 10 years, acne and fungal infection, 11 to 30 years, and contact dermatitis and fungal infection, 31 to 50 years.
Acne Vulgaris ; Dermatitis, Contact ; Female ; Humans ; Incidence ; Insect Bites and Stings ; Insects ; Male ; Outpatients* ; Psoriasis ; Pyoderma ; Red Cross ; Scabies ; Seoul ; Sex Ratio ; Skin ; Skin Diseases ; Statistics as Topic* ; Syphilis ; Urticaria

Cerebral malaria means that the patient with demonstrable asexual forms of Plasmodium falciparum in peripheral blood smear who have disturbed mental state and in whom other causes of encephalopathy, such as bacterial, fungal, or viral meningoenoephalitides, drug intoxications other metabolic disease have been excluded. In cerebral malaria, the mortality rate is up to 30% and most of death is within 96 hours, so is known as neurological emergency that urgent treatment should be required. A 42 years old male patients admitted our emergency room with spiking fever 2 days before admission and drowsy mental state at the moming of admission day. The patient traveled in Africal 2 weeks ago. On physical and neurologic examination, the hepatomegaly, drowsy mental state and divergent eyeball was observed. Brain CT scan was normal but pulmonary edema was seen in chest PA and mild increased protein(76mg/dl) was observed in spinal tapping. In peripheral blood smear, severe thrombocytopenia and trophozoa of ring form and band form wer found so diagnosed as mixed infected cerebral malaria. The patient was started the treatment of chloroguine and tetracycline and recovered 2 weeks after treatment. Cerebral malaria should be once considered as differential diagnosis in patients with unknown origin fever and mental confusion in intemalized society like modem.
Adult ; Brain ; Diagnosis, Differential ; Emergencies ; Emergency Service, Hospital ; Fever ; Fever of Unknown Origin ; Hepatomegaly ; Humans ; Malaria, Cerebral* ; Male ; Metabolic Diseases ; Modems ; Mortality ; Neurologic Examination ; Plasmodium falciparum ; Pulmonary Edema ; Spinal Puncture ; Tetracycline ; Thorax ; Thrombocytopenia ; Tomography, X-Ray Computed

A case of systemic coccidioidomycosis with cutaneous lesions has been found in Dec. 1974, for the first time in Korea, which is proved through cutaneous biopsy .and mycologic culture from skin lesion. The patient was 57-year-old Korean male. Skin lesions on left extremities showed several skin colored or ligbt brownish papules and surrounding circular erythematous scaly patches with slightly elevated borders. The patient was also found to have moderate diabetes mellitus, hypokalemia and resultant neuropathy. Histopathology revealed granulomatous lesions in the upper dermis, and numerous spherules both inside and outside of giant cells. Mycologic culture from grind skin specimen on Sabourauds glulose agar showed snow-white colony and ather typical arthrospores. Ampbotericin B intravenous injection was started and continued for 16 days. During a,dministration of the drug, side effects consisting of chills, fever, headache, chest pain and dyspnea developed. Therefore, further administration of the drug could not be done. During tbe several months following last discharge from the hospital, the patient has been, with no further specific therapy, in relatively good general condition, and developed no new lesions. The old papules have diminished in size, but did not disappear.
Agar ; Biopsy ; Chest Pain ; Chills ; Coccidioidomycosis* ; Dermis ; Diabetes Mellitus ; Dyspnea ; Extremities ; Fever ; Giant Cells ; Headache ; Humans ; Hypokalemia ; Injections, Intravenous ; Korea ; Male ; Middle Aged ; Skin

Acrodynia is caused by chronic mercury poisoning and/or mercury, hypersensitivity occuring in infants and children only. Ingestion or inhalation of mercury contained in some house paints, calomel ingestion, the use of mercury ointments and other mercurial preparations can be the causes of acrodynia. We herein report a 3-year-old boy with typical acrodynia after expoaure to house paints and lacquer for 2 months. His hands and feet were erythematous and edematous vesiculo-bullous lesion with acral dark bluish discoloration. Mercury levels of blood and urine were significantly incresed by 61. 2ug/dl and 264ug/L (normal; below 30ug/dl and 100ug/L).
Acrodynia* ; Child ; Child, Preschool ; Eating ; Foot ; Hand ; Humans ; Hypersensitivity ; Infant ; Inhalation ; Lacquer ; Male ; Mercury Poisoning ; Ointments ; Paint