Retinitis Punctata Albescens is a condition characterized by night blindness and the presence of multiple small discrete white dots scattered over the fundus except in the macular area. Progressive form is progressive loss of the visual field, deterioration of central vision, anomalies of color vision, night blindness, some optic atrophy and occasionally appearance of pigmentary changes. Stationary form is benign evolution, little or no constriction of the visual field, good visual acuity and the presence of white dots in the fundus without pigmentary changes. Recently, the authors have been experienced Retinitis Punctata Albescens in 50-year-old male whose complaint was night blindness and slight impairment of visual acuity. Clinical, ophthalmoscopic examination, visual field test, color vision test, fluorescein angiography and electroretinography were performed in patient.
Color Vision ; Constriction ; Electroretinography ; Fluorescein Angiography ; Humans ; Male ; Middle Aged ; Night Blindness ; Optic Atrophy ; Retinitis* ; Visual Acuity ; Visual Field Tests ; Visual Fields

No abstract available.
Anterior Temporal Lobectomy* ; Seizures*

No abstract available.
Congenital Abnormalities* ; Spondylitis, Ankylosing*

We report a case of coincidental pituitary adenoma and sphenoid meningioma. Computed tomographic scan had shown a large intrasellar rim enhancing mass and another well-enhancing mass with reactive bony thickening on the medial sphenoidal ridge. Magnetic resonance image revealed a snow-man shaped, expansile intrasellar mass, with small supra-sellar component, and a small enplaque-type enhancing dural thickening on the right medial sphenoidal ridge. Histopathologically, the intrasellar mass was diagnosed as pituitary adenoma and the other mass as secretory meningioma. We present clinical, radiological, and histopathological findings and review the reported cases of coincidental pituitary adenoma and meningioma without irradiation or trauma.
Brain Neoplasms ; Meningioma* ; Pituitary Neoplasms* ; Sphenoid Bone

A 64-year-old female presented with unconscious state after sudden onset headache, nausea and vomiting. Computed tomography showed acute subdural hematoma (SDH) over the left convexity without subarachnoid hemorrhage. 3D-CT angiogram showed a saccular aneurysm at the junction of A2-A3 of the left anterior cerebral artery. Surgery for decompressive craniotomy and aneurysmal neck clipping was performed. In operative field, the left distal anterior cerebral artery was abnormally elongated toward the frontal pole and located not in the pericallosal cistern but on the cortical surface and the rupturing point was located in the adhesive portion of aneurysmal sac and arachnoid membrane near the falx. Pure acute SDH without subarachnoid hemorrhage (SAH) caused by ruptured aneurysm is extremely rare. Rupture of an aneurysm adhered to either the dura or falx and located in the subdural space may cause pure SDH. In our case, abnormally elongated location of artery may be related to this adhesion and rupture of aneurysm to subdural space. Therefore, ruptured intracranial aneurysm should be considered as a cause of non-traumatic SDH. Immediate removal of the SDH and aneurysmal clipping is recommended in such patients, even those in poor neurological condition.
Adhesives ; Aneurysm ; Aneurysm, Ruptured ; Anterior Cerebral Artery* ; Arachnoid ; Arteries ; Craniotomy ; Female ; Headache ; Hematoma, Subdural, Acute* ; Humans ; Intracranial Aneurysm* ; Membranes ; Middle Aged ; Nausea ; Neck ; Rupture* ; Subarachnoid Hemorrhage ; Subdural Space ; Unconsciousness ; Vomiting

BACKGROUND/AIMS: Since 1980 a group of pancreatic tumors have been termed intraductal papillary mucinous tumors (IPMT). Controversy about the term and clinico pathologic entity still exist. This study compared the clinicopathlogic features, imaging, prognostic differences between mucinous cystic tumors (MCT) and intraductal papillary mucinous tumors (IPMT) of pancreas. METHODS: We reviewed 7 operated patients between January of 1997 to December of 2000, retrospectively by clinical record. 4 patients with mucinous cystic tumors and 3 patients with intraductal papillary mucinous tumors. RESULTS: Gender, age, symptoms, signs, tumor location and size, the presence or abscece of communication with the pancreatic duct differed between two types. Mucinous cystic tumors showed single cyst, located in pancreatic tail. Intraductal papillary mucinous tumor showed pancreatic duct dilatation & mucin plug, located in pancreatic head & body. 4 patients of mucinous cystic tumor were received distal pacreatectomy. 2 patients of intraductal papillary mucinous tumor received pancreaticoduodenectomy. 1 patient of intraductal papillary mucinous tumor received distal pancreatectomy. CONCLUSIONS: Mucinous cystic tumors and Intraductal papillary mucinous tumors were different clinicopathologic entities. Complete resection should be attempted for these mucin producing tumors.
Dilatation ; Head ; Humans ; Mucins* ; Pancreas ; Pancreatectomy ; Pancreatic Ducts ; Pancreaticoduodenectomy ; Retrospective Studies

Natural isoflavones and flavones are important dietary factors for prostate cancer prevention. We investigated the molecular mechanism of these compounds (genistein, biochanin-A and apigenin) in PC-3 (hormone-independent/p53 mutant type) and LNCaP (hormone-dependent/p53 wild type) prostate cancer cells. A cell growth rate and apoptotic activities were analyzed in different concentrations and exposure time to evaluate the antitumor activities of genistein, biochanin-A and apigenin. The real time PCR and Western blot analysis were performed to investigate whether the molecular mechanism of these compounds are involving the p21 and PLK-1 pathway. Apoptosis of prostate cancer cells was associated with p21 up-regulation and PLK-1 suppression. Exposure of genistein, biochanin-A and apigenin on LNCaP and PC-3 prostate cancer cells resulted in same pattern of cell cycle arrest and apoptosis. The inhibition effect for cell proliferation was slightly greater in LNCaP than PC-3 cells. In conclusion, flavonoids treatment induces up-regulation of p21 expression, and p21 inhibits transcription of PLK-1, which promotes apoptosis of cancer cells.
Antineoplastic Agents/*pharmacology ; Apigenin/pharmacology ; *Apoptosis ; Cell Cycle/drug effects ; Cell Cycle Proteins/biosynthesis/*genetics/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Cyclin-Dependent Kinase Inhibitor p21/biosynthesis/*metabolism ; Flavonoids/*pharmacology ; Gene Expression Regulation, Neoplastic/drug effects ; Genistein/pharmacology ; Humans ; Male ; Prostatic Neoplasms/genetics/metabolism/*pathology ; Protein Kinase Inhibitors/pharmacology ; Protein-Serine-Threonine Kinases/biosynthesis/*genetics/metabolism ; Proto-Oncogene Proteins/biosynthesis/*genetics/metabolism ; Transcription, Genetic/drug effects

No abstract available.
Periodontal Diseases*

BACKGROUND: Piriformis syndrome (PS) is an uncommon disease characterized by symptoms resulting from compression/irritation of the sciatic nerve by the piriformis muscle. Uncertainty and controversy remain regarding the proper diagnosis and most effective form of treatment for PS. This study analyzes the diagnostic methods and efficacy of conservative and surgical treatments for PS. METHODS: From March 2006 to February 2013, we retrospectively reviewed 239 patients who were diagnosed with PS and screened them for eligibility according to our inclusion/exclusion criteria. All patients underwent various conservative treatments initially including activity modification, medications, physical therapy, local steroid injections into the piriformis muscle, and extracorporeal shock wave therapy for at least 3 months. We resected the piriformis muscle with/without neurolysis of the sciatic nerve in 12 patients who had intractable sciatica despite conservative treatment at least for 3 months. The average age of the patients (4 males and 8 females) was 61 years (range, 45 to 71 years). The average duration of symptoms before surgery was 22.1 months (range, 4 to 72 months), and the mean follow-up period was 22.7 months (range, 12 to 43 months). We evaluated the degree of pain and recorded the responses using a visual analog scale (VAS) preoperatively and 3 days and 12 months postoperatively. RESULTS: Buttock pain was more improved than sciatica with various conservative treatments. Compared with preoperatively, the VAS score was significantly decreased after the operation. Overall, satisfactory results were obtained in 10 patients (83%) after surgery. CONCLUSIONS: PS is thought to be an exclusively clinical diagnosis, and if the diagnosis is performed correctly, surgery can be a good treatment option in patients with refractory sciatica despite appropriate conservative treatments.
Buttocks ; Diagnosis ; Follow-Up Studies ; Humans ; Male ; Piriformis Muscle Syndrome* ; Retrospective Studies ; Sciatic Nerve ; Sciatica ; Shock ; Uncertainty ; Visual Analog Scale