1.In vitro 31P NMR spectroscopic assessment of the endurance and recovery capacity of skeletal muscle: comparison between the sedentaries and canoe athletes.
Tae Hawn LIM ; Tae Keun LEE ; Ki Hong SEONG ; Chi Woong MUN ; Sang Tae KIM ; Myung Jin SHIN
Journal of the Korean Radiological Society 1992;28(5):776-782
In vivo 31P NMR spectroscopic study of forearm wrist flexor muscles was performed in two groups of volunteers composed respectively of 6 sedentaries and 6 canoe athletes. A continuous isometric contraction of endurance exercises was adopted in oder to assess the endurance capacity and recovery potential of skeletal muscles. Differences in high energy phosphorus metabolism between the sedentaries and athletes were evaluated with and emphasis on the intracellular pH and Pi/PCr ratio as indicators of high energy phosphorus metabolism. There were no differences of baseline pH and Pi/PCr ratio between the two groups. The athletes sustained the exercise at more acidic intracellular pH and at a higher Pi/PCr ratio of intracellular conditions for an all-out than did the sedentaries. The recovery rate of pH showed no difference between the two groups. There was a tendency of faster recovery of Pi/PCr in athletes showing half recovery time(T1/2) of 39.0±3.0 seconds as compared to that of sedentaries (55.7±7.5 seconds). The recovery rate of Pi/PCr as a function of Pi/PCr ratio at a given period of time was significantly faster in athletes than in sedentaries (P<0.001). The correlation coefficient of the recovery rate of Pi/PCr against the Pi/PCr ratio was 0.985 and 0.914 respectively for the athletes and sedentaries. The pH and the Pi/PCR ratio at an all-out state can be used as indicators of endurance capacity and the recovery rate of Pi/PCr, as a reovery potential of skeletal muscles.
Athletes*
;
Exercise
;
Forearm
;
Humans
;
Hydrogen-Ion Concentration
;
In Vitro Techniques*
;
Isometric Contraction
;
Metabolism
;
Muscle, Skeletal*
;
Muscles
;
Phosphorus
;
Volunteers
;
Wrist
2.The change of lymphocyte subpopulation of the thermal injured rats by exchange transfusion.
Ki Taek HAN ; Kyung Seul CHUNG ; Jung Gil CHUNG ; Sang Tae AHN ; Poong LIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(3):327-337
No abstract available.
Animals
;
Lymphocyte Subsets*
;
Lymphocytes*
;
Rats*
3.Clinical Study of Cerebral Blood Flow in Patients with Subarachnoid Hemorrhage Due to Ruptured Intracranial Aneurysms.
Young Jin LIM ; Tae Sung KIM ; Gook Ki KIM ; Bong Arm RHEE ; Won LEEM
Journal of Korean Neurosurgical Society 1990;19(10-12):1258-1275
This study was carried out to find out changes in regional cerebral blood flow(r-CBF) in relation to(i) clinical status of patients with subarachnoid hemorrhage due to ruptured intracranial aneurysms ; (ii) the degree of subarachnoid hemorrhage as indicated by brain CT scanning ; (iii) the severity of angiographic vasospasm, and (iv) other neuropathological condition. Measurement of r-CBF were performed, using 133Xe inhalation method, on 50 patients with ruptured intracranial aneurysms. Some of the major findings were as follows : 1) The degree of abnormalities of blood flow correlated well with the clinical severity of neurological deficits. 2) A marked reduction in r-CBF was found in patients with intracerebral hematoma, ischemic lesion and hydrocephalus. 3) In angiospasm area, r-CBF was found in patients with intracerebral hematoma, ischemic lesion and hydrocephalus. 3) In angiospasm area, r-CBF decreases below 30ml/100gm/min in almost all of the patients, and severity of vasospasm correlated with the decrease of CBF. 4) The measurement of CBF on patients with subarachnoid hemorrhage was thought to the useful for foreseeing the clinical outcome of the patients.
Brain
;
Hematoma
;
Humans
;
Hydrocephalus
;
Inhalation
;
Intracranial Aneurysm*
;
Subarachnoid Hemorrhage*
;
Tomography, X-Ray Computed
4.EMA-CO regimen in high-risk gestational trophoblastic disease.
Sang Lim CHOI ; Yong Hak KIM ; Ki Tae KIM ; Hyun Chan KIM
Korean Journal of Obstetrics and Gynecology 1992;35(1):85-96
No abstract available.
Gestational Trophoblastic Disease*
5.Changes of lymphocyte subpopulation & histologic finding of thymus and spleen after thermal burn in mouse.
Ki Taek HAN ; Yoon Seob KANG ; Sang Tae AHN ; Poong LIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(4):587-596
No abstract available.
Animals
;
Burns*
;
Lymphocyte Subsets*
;
Lymphocytes*
;
Mice*
;
Spleen*
;
Thymus Gland*
6.CT Evaluation of Solitary Pulmonary Nodule.
Won Dong KIM ; Koun Sik SONG ; Young Hwan KIM ; Tae Hwan LIM ; Ki Young KO
Journal of the Korean Radiological Society 1995;32(1):85-91
PURPOSE: To evaluate criteria for differentiating benign versus malignant solitary pulmonary nodules (SPNs) by analyzing their morphology and perinodular parenchymal changes on CT/HRCT. MATERIALS AND METHODS: We retrospectively reviewed the CT/HRCT in 99 patients with SPN. Sixty two cases were proved by surgery, PCNA, clinical follow up and etc. Thirty seven cases were diagnosed by typical benign calcification. We defined SPN as a discrete, single lesion in the lung with margins that are sharp enough to permit measurement of diameter. We excluded lesions more than 4cm in diameter and lesions with cavity from our study protocol. The study included 41 malignant nodules and 58 benign nodules. RESULTS: Mean diameter of malignant nodule was 2.9cm, benign nodule was 2.2cm. Peripheral location of nodule was 28 in malignant nodules, 50 in benign nodules. Typical benign calcification was observed in 37 tuberculoma and three hamartoma. Lobulated margin was noted in 32 malignant nodules and 14 benign nodules. Spiculated margin was observed in 17 malignant nodules and 20 benign nodules. Low attenuation within the nodule was observed in 14 malignant nodules and 12 benign nodules. Pleural tail was observed in 14 malignant nodules and 31 benign nodules. Air bronchogram was noted in 18 malignant nodules and 4 benign nodules. Juxta nodular tuberculosis was observed in 6 malignant nodules and 29 benign nodules. CONCLUSION: Malignant nodules were larger than benign nodules and more commonly demonstrated a Iobulated contour and air bronchogram (p<0.05). Benign nodules more commonly demonstrated low density in the nodule and associated with juxta nodular tuberculosis and peripheral location (p<0.05). Spiculated margin and pleural tail were not helpful to differentiate benign from malignant nodule.
Follow-Up Studies
;
Hamartoma
;
Humans
;
Lung
;
Proliferating Cell Nuclear Antigen
;
Retrospective Studies
;
Solitary Pulmonary Nodule*
;
Tuberculoma
;
Tuberculosis
7.CT Evaluation of Solitary Pulmonary Nodule.
Won Dong KIM ; Koun Sik SONG ; Young Hwan KIM ; Tae Hwan LIM ; Ki Young KO
Journal of the Korean Radiological Society 1995;32(1):85-91
PURPOSE: To evaluate criteria for differentiating benign versus malignant solitary pulmonary nodules (SPNs) by analyzing their morphology and perinodular parenchymal changes on CT/HRCT. MATERIALS AND METHODS: We retrospectively reviewed the CT/HRCT in 99 patients with SPN. Sixty two cases were proved by surgery, PCNA, clinical follow up and etc. Thirty seven cases were diagnosed by typical benign calcification. We defined SPN as a discrete, single lesion in the lung with margins that are sharp enough to permit measurement of diameter. We excluded lesions more than 4cm in diameter and lesions with cavity from our study protocol. The study included 41 malignant nodules and 58 benign nodules. RESULTS: Mean diameter of malignant nodule was 2.9cm, benign nodule was 2.2cm. Peripheral location of nodule was 28 in malignant nodules, 50 in benign nodules. Typical benign calcification was observed in 37 tuberculoma and three hamartoma. Lobulated margin was noted in 32 malignant nodules and 14 benign nodules. Spiculated margin was observed in 17 malignant nodules and 20 benign nodules. Low attenuation within the nodule was observed in 14 malignant nodules and 12 benign nodules. Pleural tail was observed in 14 malignant nodules and 31 benign nodules. Air bronchogram was noted in 18 malignant nodules and 4 benign nodules. Juxta nodular tuberculosis was observed in 6 malignant nodules and 29 benign nodules. CONCLUSION: Malignant nodules were larger than benign nodules and more commonly demonstrated a Iobulated contour and air bronchogram (p<0.05). Benign nodules more commonly demonstrated low density in the nodule and associated with juxta nodular tuberculosis and peripheral location (p<0.05). Spiculated margin and pleural tail were not helpful to differentiate benign from malignant nodule.
Follow-Up Studies
;
Hamartoma
;
Humans
;
Lung
;
Proliferating Cell Nuclear Antigen
;
Retrospective Studies
;
Solitary Pulmonary Nodule*
;
Tuberculoma
;
Tuberculosis
8.The Value of Tc-99m DTPA Diuretic Renography for Assessment of Dilated Upper Urinary Tract in Children.
Hyung Sun SOHN ; Gye Yeon LIM ; Ki Ra YANG ; Seong Tae HAHN ; Jae Mun LEE
Korean Journal of Nuclear Medicine 1999;33(1):57-64
PURPOSE: The purpose of this study was to evaluate the accuracy of Tc-99m DTPA diuretic renal scans in children upper urinary tract. MATERIALS AND METHODS: We reviewed diuretic renal scans of 14 pediatric patients (age range: 3 days to 4 years) with unilateral hydronephrosis diagnosed by ultrasonography. Diuretic renal scan was done using Tc-99m DTPA and standardized protocol. In 3 neonates, diuretic renal scans were performed within 1 week and 3-7 months after birth. RESULTS: Six patients required pyeloplasty and eight were managed conservatively. All 6 patients requiring pyeloplasty were diagnosed as having ureteropelvic junction obstruction in the diuretic renal scan. In these 6 patients, post-operative renal scans at 3-12 months after surgery were converted to nonobstructive pattern in 5 and a nonobstructive patterns in 1. In 3 patients who underwent diuretic renal scan within 1 week after birth., nonobstructive patterns of initial scan were coverted to obstructive patterns in the follow-up scan. However, all patients with nonobstructive diuretic renal scans performed after the neonatal period did well on serial ultrasonography and showed favorable clinical outcome without progression to obstruction. CONCLUSION: Tc-99m DTPA diuretic renal scan with standarized protocol is useful in assessing suspected ureteropelvic junction obstruction in children as an initial diagnostic or post-operative follow-up modality. Nonobstructive or indeterminate scan RESULTS in the neonatal period requires follow-up scan to monitor development of the obstructive pattern.
Child*
;
Follow-Up Studies
;
Humans
;
Hydronephrosis
;
Infant, Newborn
;
Kidney Pelvis
;
Parturition
;
Pentetic Acid*
;
Radioisotope Renography*
;
Ultrasonography
;
Urinary Tract*
9.Cryopreservation of Human Embryos.
Tae Ki YOON ; Hyung Min CHUNG ; Jeong Mook LIM ; Kwang Yul CHA
Korean Journal of Obstetrics and Gynecology 1999;42(12):2648-2656
Technology for the long-term preservation of gamete and embryo has improved greatly over the past 20 years and currently is used for supporting various assisted reproductive technologies (ART). Recent progress in cryobiology and its related sciences have made it possible to preserve human embryos effectively, and several cryopreservation methods also have been developed. Successful freezing of supernumerary embryos has allowed patients undergoing ART the opportunity to achieve pregnancies from more than one embryo transfer without being subjected to controlled ovarian hyperstimulation and oocyte retrieval each time. It also allows a delay in embryo transfer where certain adverse conditions exist for fresh transfer, e.g. when the patient is at risk for ovarian hyperstimulation syndrome or when there is poor endometrial development during the retrieval cycle. Cryopreservation of all available embryos from retrieval is utilized when an oocyte recipient is not properly synchronized with oocyte donor's cycle. In this paper is to review the current status and perspectives of embryo cryopreservation in ART program. Also, briefly discuss the oocyte cryopreservation for the establishment of ovum bank.
Cryopreservation*
;
Embryo Transfer
;
Embryonic Structures*
;
Female
;
Freezing
;
Humans*
;
Oocyte Retrieval
;
Oocytes
;
Ovarian Hyperstimulation Syndrome
;
Ovum
;
Pregnancy
;
Reproductive Techniques, Assisted
10.Intraoperative use of Real-time Ultrasonography in Neurosurgery.
Nam In KIM ; Young Jin LIM ; Tae Sung KIM ; Gook Ki KIM ; Bong Arm RHEE ; Won LEEM
Journal of Korean Neurosurgical Society 1991;20(1-3):3-12
Recent technological advances in ultrasound instrumentation have resulted in equipment that will image in "real-time" slices of the human brain similar in quality to computerized tomography(CT). Multiple authors have attested to its usefulness in locatin, characterizing, and facilitating in the biopsy or removal, or both, of intracerebral masses. In this study, the author has examined the efficacy of intraoperative neurosurgical ultrasound in 18 patients who were admitted to the Department of Neurosurgery, Kyung Hee University Hospital. The results were as follows : 1) It can provide critical assistance in precise localization of subcortical masses, since in many instances the overlying surface of brain provides no clue for localization. 2) This technique is very useful for the identificantion of deep lesions, provding infromation about their solid and cystic components and about the shortest route of access to tumor. 3) It provides precise information to help guide biopsy needles into deep lesions, and to confirm their presence within the lesion itself. 4) The system is highly accurate in visualizing ventricular catheters during and after their placement. 5) The system is inherently safe for the patient and the operating room personnel since there is no radiation exposure.
Biopsy
;
Biopsy, Needle
;
Brain
;
Catheters
;
Humans
;
Needles
;
Neurosurgery*
;
Operating Rooms
;
Ultrasonography*