A 23-year-old man had multiple small, skin-colored firm papules on the both sides of the nasolabial folds since the age of approximately 17. His mother had a similar skin lesions on her face. The histopathological findings of skin biopsy specimens from patient(son) showed horn cysts consist of a fully keratinized center surrounded by basophilic cells and tumor islands composed of basophilic cells arranged in a lacelike or adenoid network and occasional solid aggregates and there are also a foreign body giant cell reaction in the vicinity of the ruptured horn cysts.
Adenoids ; Animals ; Basophils ; Biopsy ; Giant Cells, Foreign-Body ; Heredity ; Horns ; Humans ; Islands ; Mothers* ; Nasolabial Fold ; Skin ; Young Adult

No abstract available.
Diagnosis*

No abstract available.

No abstract available.
Clonidine* ; Depression* ; Growth Hormone* ; Humans ; Panic Disorder* ; Panic*

No abstract available.
Dislocations* ; Hip* ; Osteotomy*

We present a case of mycosis fungoides of an 52-year-old woman who showed multiple pruritic erythematous papules, plaques with ulcers on the trunk, extremities and face. Her skin biopsy specimens were studied irnmunohistochemically with, monoclonal antibodies against T cells(80%, Leu-4, OKT11), T-cell subsets (60% Leu-3a, OKT4a, 40% OKT8) and Langerhans cell(OKT6). We think that this case should be considered in the differential diagnosis of adult T-cell leukemia/lymphoma. The proliferating cells were negative for anti-Tac.
Adult ; Antibodies, Monoclonal ; Biopsy ; Diagnosis, Differential ; Extremities ; Female ; Humans ; Middle Aged ; Mycosis Fungoides* ; Skin ; T-Lymphocyte Subsets ; T-Lymphocytes ; Ulcer

There are several methods available to check bone masses. One of them is Singhs index which is singlest way with grading trabecular pattern of the proximal femur on anteroposterior X-ray film and the other is recently developed Dual Photon X-ray Absorptiometry which measures bone mineral contents. Some authors proclaim that Singh's index has low accuracy, objectiveness and reproducibility. So we studied for reliability of Singh's index and correlation between Singh's index and bone mineral contents measured by Dual Photon X-ray Absorptiometry in 65 patients. There are significant differences between 3 orthopedic surgeons in interpreting Singh's index (interpersonal difference). There are significant differences between first and second interpretation out of same surgeons (intrapersonal difference). There are significant differences interpretating among interpreted Singh's indices from films of different radiological exposures in the same radiograph. There are fair correlations(0.60-0.66) between Singhs index and bone mineral density. The Singh's index was overestimated in low bone mineral density with under-exposed radiograph, but Singh's index was under-estimated in high bone mineral density with over-exposed radiograph. Singh's index can be useful in clinical application by some modification.
Absorptiometry, Photon ; Bone Density ; Femur ; Humans ; Orthopedics ; Surgeons ; X-Ray Film

PURPOSE: To assess the difference between auditory and visual stimuli when determining hemispheric language dominance by using functional MRI. MATERIALS AND METHODS: In ten healthy adult volunteers (8 right-handed, 1 left-handed, 1 ambidextrous), motor language activation in axial slices of frontal lobe was mapped on a Simens 1.5T Vision Plus system using single-shot EPI. Series of 120 consecutive images per section were acquired during three cycles of task activation and rest. During each activation, a series of four syllables was delivered by means of both a visual and auditory method, and the volunteers were asked to mentally generate words starting with each syllable. In both inferior frontal gyri and whole frontal lobes, lateralization indices were calculated from the activated pixels. We determined the language dominant hemisphere, and compared the results of the visual method and the auditory method. RESULTS: Seven right-handed persons were left-hemisphere dominant, and one left-handed and one ambidextrous person were right-hemisphere dominant. Five of nine persons demonstrated larger lateralization indices with the auditory method than the visual method, while the remaining four showed larger lateralization indices with the visual method. No statistically significant difference was noted when comparing the results of the two methods(p>0.05). CONCLUSION: When determining hemispheric language dominance using functional MRI, the two methods are equally appropriate.
Adult ; Frontal Lobe ; Humans ; Magnetic Resonance Imaging* ; Volunteers

No abstract available.
Acute Kidney Injury* ; Humans ; Pancreatitis*

Using peanut agglutinin(PNA), neurarninidase, and avidin-biotin peroxidase com plex(ABC) technique, normal skin specimens, nevocellular nevi, and malignant melanomas were studied, and different PNA binding patterns between nevocellular nevi and malignant melanomas were observed. The results were as follows : 1. In normal skin, except the basement membrane, epidermis and hair follicle epithelium showed a cell membrane staining of PNA after neuraminidase pretreat ment. Sebaceous glands revealed membranous and cytoplasmic staining of PNA, but sweat ducts were not stained. 2. In nevocellular nevi, none of the nevus cells were stained with PNA aftet neuraminidase preteatment. 3. In malignant melanomas, all of the melanorna cells were stained along the cell mernbrane with PNA after neuraminidase pretreatment. Therefore, the PNA staining after neuraminidase pretreatment on paraffin embedded sections using ABC technique is considered to be a useful probe for the differentiation between malignant malanoma and nevocellular nevus.
Basement Membrane ; Cell Membrane ; Cytoplasm ; Epidermis ; Epithelium ; Hair Follicle ; Melanoma* ; Neuraminidase ; Nevus* ; Paraffin ; Peanut Agglutinin* ; Peroxidase ; Sebaceous Glands ; Skin ; Sweat