1.An Immunohistochemical Study for the neu and ras Oncoprotein and Epidermal Growth Factor Receptor in the Breast Carcinoma.
Jeong Ja PARK ; Tae In PARK ; Tae Joong SOHN ; In Soo SUH
Korean Journal of Pathology 1994;28(2):126-134
To evaluate correlation between the expression of neu and ras oncoprotein and epidermal growth factor receptor on breast carcinoma and other known prognostic factors, immunohisto-chemical studies were performed. Positive reaction for neu, which appeared as brown granular deposits along cell surface and cytoplasm of the tumor cells, was significantly correlated with the histological grade but not with other prognostic factors such as tumor size, lymph node me-tastasis, local recurrence, and estrogen and progesteron receptor status. Also granular deposits of ras were noted in the carcinoma cells in the cytoplasm, while the epithelaial cells of the normal lobule and duct showed negative reation. But expression of ras was not significantly associated ras with other prognostic factors. The reaction for EGFR was mostly negative on epithelial cells of both the normal lobule and duct, and was not significantly associated with other prognostic factors. The results suggested that expression of the neu oncoprotein is significantly associated with the histological grade of breast carcinoma, while the ras and the EGFR do not show significant prognostic value.
Breast Neoplasms
2.Solitary Bone Cyst of the Proximal Femur Mimicking Fibrous Dysplasia: A Case Report
Myoung Sik PARK ; Tae Sub JEONG
The Journal of the Korean Orthopaedic Association 1985;20(2):373-376
The following case of solitary bone cyst of the proximal femur was misdiagnosed as fibrous dysplasia because of similarity of X-ray findings and was confirmed by histological findings. The cyst was treated by curettage, packing with autogenous iliac bone and kiel bone graft and internal fixation with Ender nail. The most recent evaluation one year after surgery showed no pain and recurrence.
Bone Cysts
;
Curettage
;
Femur
;
Recurrence
;
Transplants
3.Biological detection of enterotoxigenic E. coli.
Jeong Kyu PARK ; Seong Kyu PARK ; Hwa Jung KIM ; Tae Hyun PAIK ; Tae Kyung CHOI
Journal of the Korean Society for Microbiology 1991;26(3):215-222
No abstract available.
Enterotoxigenic Escherichia coli*
4.In vitro transposition of Tn5.
Byung Tae PARK ; Min Ho JEONG ; Bong Hoon KIM
Journal of the Korean Society for Microbiology 1992;27(4):381-389
No abstract available.
5.Detection of mycobacterium tuberculosis in sputum samples by polymerase chain reaction.
Eun Gyeong JO ; Tae Kyung CHOI ; Tae Hyun PAIK ; Jeong Kyu PARK ; Hwa Jung KIM
Journal of the Korean Society for Microbiology 1993;28(2):131-142
No abstract available.
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Polymerase Chain Reaction*
;
Sputum*
6.Purification of 30-kDa and 32 kDa protein antigens from mycobacterium tuberculosis and activation of human monocytes by lymphokines.
Tae Kyung CHOI ; Hwa Jung KIM ; Eun Gyeong JO ; Jeong Kyu PARK ; Tae Hyun PAIK
Journal of the Korean Society for Microbiology 1993;28(2):113-130
No abstract available.
Humans*
;
Lymphokines*
;
Monocytes*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
7.Nonspecific Empirical Medical Therapy with Acetylcarnitine Effective in Oligoasthenospermic Men?.
Jong Woo KIM ; Jae Seok LEE ; Jeong Su PARK ; Won Tae KIM ; Ju Tae SEO
Korean Journal of Fertility and Sterility 2004;31(3):177-182
PURPOSE: To determine the efficacy of CarnitilR (acetylcarnitine, Hanmi, Korea) therapy in idiopathic oligoasthenospermic men. MATERIALS AND METHODS: Forty-four subfertile men with abnormal semen parameters were treated between March, 2003 and March, 2004 with 3 g of CarnitilR daily for 3 months. Changes in semen parameters were evaluated 3 months after this therapy. RESULTS: The mean age was 34.2 years and the mean follow-up duration was 3.7 months. In asthenospemic patients (n=28), semen analysis before and after CarnitilR treatment showed an increase in volume (2.64+/-1.65 ml vs. 3.10+/-1.60 ml), motility (35.1+/-17.7% vs. 45.9+/-20.4%) and viability (51.4+/-20.3% vs. 59.3+/-13.6%) respectively. In oligoasthenospermic patients (n=16), semen analysis before and after CarnitilR treatment showed an increase in sperm count (10.7+/-54.4 million/ml vs. 38.4+/-32.5 million/ml) respectively. CONCLUSIONS: These results suggested that in idiopathic oligoasthenospermic men the empirical medical therapy with acetylcarnitine may be considered as primary treatment.
Acetylcarnitine*
;
Carnitine
;
Follow-Up Studies
;
Humans
;
Infertility, Male
;
Male
;
Semen
;
Semen Analysis
;
Sperm Count
8.Purification and immunochemical charaterization of alpha-antigen from the culture filtrate of mycobacterium tuberculosis.
Seok Kwun KIM ; Tae Hyun PAIK ; Hwa Jung KIM ; Jeong Kyu PARK ; Tae Kyung CHOI
Journal of the Korean Society for Microbiology 1991;26(1):45-60
No abstract available.
Mycobacterium tuberculosis*
;
Mycobacterium*
9.Determination of antibody activities of alpha- and beta-protein antigens of mycobacterium tuberculosis in cerebrospinal fluid by ELISA for the diagnosis of tuberculous meningitis.
Kyung Suk LEE ; Tae Hyun PAIK ; Hwa Jung KIM ; Jeong Kyu PARK ; Tae Kyung CHOI
Journal of the Korean Society for Microbiology 1991;26(1):37-43
No abstract available.
Cerebrospinal Fluid*
;
Diagnosis*
;
Enzyme-Linked Immunosorbent Assay*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Tuberculosis, Meningeal*
10.Chronic Eosinophilic Pneumonia: A Case Report.
Hae Jeong JEON ; Jeong Hee PARK ; Jong Nam LIM ; Tae Haeng HEO ; Hyun Jun SHIN
Journal of the Korean Radiological Society 1995;32(5):733-735
Chronic eosinophilic pneumonia is a rare diasease characterized by chronic infiltration of the lung with ~eosinophils, usually associated with peripheral eosinophilia. In 65% of cases, the chest rad Ogroaph shows typiical nonsegmental air-space consolidation confined to the outer third of the lung and in 25)/0 of case "photographic negative of pulmonary edema". Typical lung manifestations with 'peripheral eosinophiliSa' tahrcharacteristic of chronic eosinophilic pneumonia. In the remaining cases, radiographic findings are nonspecific and require lung biopsy for confirmation. We repot a case of chronic eosinophilic pneumonia in which chest radiograph and CT scans revealed bilateral patchy or diffuse opacity with nodules scattered throughout the lungs.
Biopsy
;
Eosinophilia
;
Eosinophils*
;
Lung
;
Pulmonary Eosinophilia*
;
Radiography, Thoracic
;
Thorax
;
Tomography, X-Ray Computed