1.Dermatitis Herpetiformis Associated with Bronchogenic Carcinoma: Report of a Case.
Duck Hyun KIM ; Hong Il KOOK ; Tae Ha WOO
Korean Journal of Dermatology 1973;11(1):53-56
A case of dermatitis herpetiformis associated with bronchogenic carcinoma is reported. The 56 year-old female patient developed cough with expectorants and exertional dyspnea one year ago, and also showed the pinhead to rice sized erythematous papulovesicular eruptions on the back and extremities with severe itching sensation one month ago. Bronchogenic carcinoma was confirmed by chest X-ray and so on. Skin biopsy was performed on the vesicular lesion and reveled subepidermal bullae with eosinophilic and neutrophilic inflammatory cells infiltertaion.
Biopsy
;
Carcinoma, Bronchogenic*
;
Cough
;
Dermatitis Herpetiformis*
;
Dermatitis*
;
Dyspnea
;
Eosinophils
;
Expectorants
;
Extremities
;
Female
;
Humans
;
Middle Aged
;
Neutrophils
;
Pruritus
;
Sensation
;
Skin
;
Thorax
2.Treatment of fracture of the femoral shaft with the Brooker-Wills distal locking intramedullary nail in adulthood.
Joo Tae PARK ; Kil Yeong AHN ; Il Hyun NAM ; Tae Hoon KIM
The Journal of the Korean Orthopaedic Association 1992;27(7):1731-1737
No abstract available.
3.The management of foreign body ingestion in gut.
Jae Chun YOON ; Sang Ho LEE ; Tae Il HYUN ; Sang Hyun RHO
Journal of the Korean Surgical Society 1993;44(6):814-819
No abstract available.
Eating*
;
Foreign Bodies*
4.Changes in Detrusor and Urinary Growth Factors According to the Bladder Function after Partial Bladder Outlet Obstruction in Rat.
Joon Chul KIM ; Seong Il SEO ; Tae Kon HWANG ; Yong Hyun PARK
Korean Journal of Urology 2000;41(10):1155-1162
No abstract available.
Animals
;
Intercellular Signaling Peptides and Proteins*
;
Rats*
;
Urinary Bladder Neck Obstruction*
;
Urinary Bladder*
5.Characterization of a Replication Element in the Coat Protein ORF of Turnip Yellow Mosaic Virus.
Journal of Bacteriology and Virology 2012;42(1):49-55
Turnip yellow mosaic virus (TYMV) is a non-enveloped icosahedral virus that has a single 6.3 kb positive-strand RNA as a genome. Previously, it was observed that the recombinant construct TY-eGFP2, where an eGFP gene was inserted at the position downstream of the coat protein (CP) ORF of TYMV genome, barely replicated. The inhibition of replication was relieved by insertion of an additional copy of the 3' quarter of the CP ORF after the foreign sequence. In this study, we have examined if the 3' quarter of the CP ORF contains any replication elements. M-fold analysis predicted three stem-loop structures in this region. Analysis of the TY-eGFP2 constructs containing one or two of these stem-loop structures indicates that the secondary structure predicted in the region between nt-6139 and nt-6181, termed SL2, is essential for TYMV replication. The critical role of SL2 was confirmed by the observation that deletion of the 3' quarter of the CP ORF from the wild-type TYMV genome nearly abolished replication and that insertion of SL2 into the deletion mutant restored the replication. Mutations disrupting the stem of SL2 greatly reduced viral RNA replication, indicating that the secondary structure is essential for the enhancing activity.
Animals
;
Brassica napus
;
Coat Protein Complex I
;
Ecthyma, Contagious
;
Genome
;
RNA
;
RNA, Viral
;
Tymovirus
;
Viruses
6.A Sequence in Coat Protein Open Reading Frame Is Required for Turnip Yellow Mosaic Virus Replication.
Journal of Bacteriology and Virology 2011;41(2):109-116
Turnip yellow mosaic virus (TYMV) is a spherical plant virus that has a single 6.3 kb positive strand RNA genome. Information for TYMV replication is limited, except that the 3'-terminal sequence and 5'-untranslated region are required for genome replication. When a foreign sequence was inserted at the position upstream of the coat protein (CP) open reading frame (ORF), replication of the recombinant TYMV was comparable to wild type, as long as an RNAi suppressor was provided. In contrast, when the foreign sequence was inserted between the CP ORF and the 3'-terminal tRNA-like structure, replication of the recombinant virus was not detected. This result suggests that the CP ORF contains an essential replication element which should be appropriately spaced with respect to the 3'-end. Analysis of TYMV constructs containing a part or a full additional CP ORF indicates that the 3' quarter of the CP ORF is required for TYMV replication.
Animals
;
Brassica napus
;
Ecthyma, Contagious
;
Genome
;
Open Reading Frames
;
Plant Viruses
;
RNA
;
Tymovirus
;
Viruses
7.Changes of Detrusor Contractility and Growth Factors in Streptozotocin-induced.
Joon Chul KIM ; Seong Il SEO ; Yong Hyun PARK ; Tae Kon HWANG
Korean Journal of Urology 2000;41(5):615-621
No abstract available.
Intercellular Signaling Peptides and Proteins*
8.The Effect of Pantethine(Pantomin(R)) on Serum Cholesterol and Triglyceride in Hyperlipidemic Patients.
Il Gyun CHOI ; Sung Hyun YOON ; Tae Hwa KIM ; Bang Hun LEE ; Chung Kyun LEE
Korean Circulation Journal 1981;11(2):115-122
The incidence of atherosclerosis in Korea seems to be much increased due to diet change after national development. The pathogenesis of atherosclerosis is not clarified and there are many hypothesis but the most recent and reliable hypothesis is the ratio of HDL-cholesterol per total cholesterol. Under the basis of this hypothesis there have been much trials to administer the agents which has effect on lipid metabolism, so we tried pantethine on 30 patients who visited Han-Yang University Hospital Internal medicine Department, and the result as follows; 1) The mean age of study population was 50.1 years of age, mean body weight was 62kg, and mean height was 160.8cm. male was 17, and female 10. 2) The associated disease of study population was <19 with> cardiovascular disease, in 19, gastrointestinal disease 3, obesity in 1 and others in 4. 3) The undesirable effect of the drug was found on 3 patients; that is, constipation on 1 patient, dizziness on 1 patient, and skin eruption on 1 patient. 4) The mean serum lipids before and after pantethine administration(levels) are as following table. In conclusion, it seems that the effect of the drug which decreases the serum lipids is mild at initial but more increasing as the time goes by and constant, and we experience little side reaction except mild dizziness, constipation and skin eruption.
Atherosclerosis
;
Body Weight
;
Cardiovascular Diseases
;
Cholesterol*
;
Constipation
;
Diet
;
Dizziness
;
Female
;
Gastrointestinal Diseases
;
Humans
;
Incidence
;
Internal Medicine
;
Korea
;
Lipid Metabolism
;
Male
;
Obesity
;
Skin
;
Triglycerides*
9.Systemic Scleroderma in Childhood.
Wook Hwa PARK ; Tae Hyun PARK ; Kyung Deuk PARK ; Dong Sik BANG ; Soo Il CHUN
Korean Journal of Dermatology 1995;33(1):183-187
The onset of systemic scleroderma in the first. decade of lif occurs in less than 1.5% of instances. Systemic sclerodrma in childhood have been characterized by less severe visceral involvement and a benign course We report a boy, aged 7 years, with a history of Raynaid; phenomenon and dysphagia. He had a mask-like face, flexion contracture of hands and knee joints, digital pitting scars, ichthyosiform skin change on leg and hyperpigrnented induration on all extremities and trunk. Antinuclear antibodies were positive in nucleolar type and Scl-70 antiocy was also present. On radiologie study, the pattern of reflux esophagitis and resorption of the listal ends of all phalanges were nated. Histopathological findings were compatible with sclerodma. He was treated with Penicillamine-D and oral corticosteroic with good improvernent.
Antibodies, Antinuclear
;
Cicatrix
;
Contracture
;
Deglutition Disorders
;
Esophagitis, Peptic
;
Extremities
;
Hand
;
Humans
;
Knee Joint
;
Leg
;
Male
;
Scleroderma, Systemic*
;
Skin
10.The Effect of Intracellular and Extracellular Ca++ on Biphasic Contraction of Bladder in Growing Rats.
Seong Il SEO ; Joon Chul KIM ; Jai Young YOON ; Yong Hyun PARK ; Tae Kon HWANG
Korean Journal of Urology 2000;41(3):444-448
No abstract available.
Animals
;
Rats*
;
Urinary Bladder*