No Abstract Available.
Retinal Detachment* ; Retinaldehyde*

No abstract available.
Humans ; Kidney Failure, Chronic* ; Kidney Transplantation* ; Thyroid Gland*

No abstract available.
Humans ; Kidney Failure, Chronic* ; Kidney Transplantation* ; Thyroid Gland*

This study was performed to investigate the clinical efficacy of intralesional recombinant interferon-γ (IFN-γ) in the treatments of warts, using a placebo comparison. Warts of each groups were injected with INF-γ containing 5×10⁶ IU/ml (high dose), 1×10⁶ IU/ml (low dose), or distilled water for injection as placebo, respectively, twice weekly for three weeks. The final therapeutic efficacy was determined on the fourth week after the beginning of therapy. Among the 74 patients with periungual warts, plantar warts, or warts of other sites, complete clearing of the treated warts at week four occurred in 56% of the 36 patients receiving the high dose IFN-γ compared to 30% of the 53 receiving the low dose IFN-γ and 17% of the 36 receiving the placebo. Marked improvement showing 75% or greater regression of wart lesions was noted as 89% of patients receiving the high dose INE compared with 55% receiving the low dose IFN and 50% receiving the placebo. The group of patients with warts of other sites showed the best response. The group receiving the high dose IFN experienced some adverse effects more frequently or more severely than the group receiving low dose IFN. However, the effects were relatively tolerable to the patients. Therefore, intralesional injection of the high dose IFN-γ may be more useful in treating warts than a low dose IFN-γ.
Humans ; Injections, Intralesional ; Interferon-gamma* ; Treatment Outcome ; Warts* ; Water

A comparative observation was done on 139 patients of the lower ureteral stone, those were applied cystoscopic manipulation with 3 different types of stone dislodger at the Department of Urology, Seoul Adventist Hospital, during the periods from Jan. 1982 to June 1985. During that periods, we applied end-loop catheter in 48 patients, blunt-tip Dormia basket in 38 patients. The results were as follows; 1. The success rate of passage of dislodger beyond the stone was the highest in filiform-tip Dormia basket (97.4%) and loop catheter was the lowest (8l.3%). 2. The success rate of the primary stone extraction with filiform-tip Dormia basket was the highest (86.8%). 3. Indwelling of the dislodger in the ureter loop catheter was the most successful method among them(62.5%). 4. Of the cases of passage beyond the stone, the success rates of the stone extraction were very high and similar in their results, as in 92.3% with loop catheter, in 90.9% with blunt-tip Dormia basket, in 91.9% with filiform-tip Dormia basket. 5. The overall success rate of stone extraction was 75.0% in loop catheter, 75.5% in blunt-tip Dormia basket 89.5% in filiform-tip Dormia basket.
Catheters ; Humans ; Seoul ; Ureter ; Urolithiasis ; Urology

Extravasation of toxic chemotherapeutic 'agents cause severe skin ulceration and necrosis which often need secondary surgical intervention. Still, there were not established antidote agent in case of extravasation with mitomycin-c. Dimethyl sulfoxide is known as an effective chemical scavenger of toxic hydroxyl free radical and sodium thiosulfate also was demonstrated significant protector from mitomycin-c induced ulceration by a few experimental studies. Author investigated necrotic area of mitomycin-c injected site and compare to the effectiveness of topical treatment with dimethyl sulfoxide and intradermal injection of sodium thiosulfate according to starting times, forty five mice were divided into 3 groups. Control group(n=5) had no treatment after subcutaneous injection of mitomycin-c. Experimental group I and 11 were 20 mice treated dimethyl sulfoxide and sodium.
Animals ; Dimethyl Sulfoxide ; Injections, Intradermal ; Injections, Subcutaneous ; Mice ; Mitomycin* ; Necrosis* ; Skin Ulcer ; Sodium* ; Ulcer

We have encountered a rare case of erythema nodosum-like leukemia cutis associated with acute myelocytic leukemia(AML) in a 57-year-old male. He was in good health until about 2 weeks prior to admission, when the systemic symptoms of high fever, anorexia, general weakness and malaise, and subcutaneous nodules developed. The nodules were multiple, red and noted bilaterally on the pretibial areas. Histological findings of his skin lesions showed diffuse cellular infiltrates intermingled with leukemic cells predominantly involving the adipose tissues. The cells displayed negative stainirig to antibodies CD3 and CD20, but positive staining to LCA. The diagnosis of AML(M4) was made by blood and bone marrow studies. He had a rapid downhill course and was discharged after 2 weeks of admission, with no anti-cancer chemotherapy.
Anorexia ; Antibodies ; Bone Marrow ; Diagnosis ; Drug Therapy ; Erythema* ; Fever ; Humans ; Leukemia* ; Leukemia, Myeloid, Acute ; Male ; Middle Aged ; Skin

Renal tuberculosis is one of the most frequent disease in the urological field of Korea for a long period of time. A clinical observation of renal tuberculosis was made on the 50 cases admitted to the Department of Urology, Korea University Hospital from January 1968 to December 1975. The results summarized as follows: 1. The ratio of number of renal tuberculosis cases admitted against total number of urological inpatients is decreasing significantly every years. 2. 31 cases out of 50, belonged to the age group of 21 to 40. 3. Both kidneys were affected in 13 cases, while 21 cases in right side only and 16 cases in left kidney. 4. The important subjective symptoms were as follows: frequency in 54%, painful urination in 40%, flank pain in 40 %, gross hematuria in 38% and asymptomatic in 1 case. 5. 32% of the cases visited to the hospital within 6 months after onset of the symptoms. 6. 56% of the cases were associated with pulmonary tuberculosis. 7. Tuberculous epididymitis were complicated in 3 cases, bone tuberculosis in 1 case and squamous cell carcinoma of the bladder was found in 1 case. 8. Increased ESR were found in 42 cases and 43 cases were within normal range of BUN. 9. Urinary findings revealed proteinuria in 94%, hematuria in 74% and pyuria in 76%. Urine AFB was found in 26 cases (52%). 10. 18 cases of AFB culture was done with drug sensitivity test, which showed that INH was the most sensitive drug, but PAS and streptomycine were sensitive in high concentration of the drugs only. 11. On the urogram, non-visualization of the kidney was found in 20 cases and delayed visualization in 15 cases while abnormal ureteral findings noted in 18 cases. 12. Nephrectomy was performed in 23 cases out of 31 operated cases and nephrostomy was done in 7 cases. 13. Histopathological findings of 23 nephrectomized kidneys disclosed parenchymal tuberculous nodules in all cases and severely atrophic changes in 3 cases.
Carcinoma, Squamous Cell ; Epididymitis ; Flank Pain ; Hematuria ; Humans ; Inpatients ; Kidney ; Korea ; Male ; Nephrectomy ; Proteinuria ; Pyuria ; Reference Values ; Streptomycin ; Tuberculosis, Osteoarticular ; Tuberculosis, Pulmonary ; Tuberculosis, Renal* ; Ureter ; Urinary Bladder ; Urination ; Urology

We have analyzed 100 urinary calculi by chemical analysis, which obtained from the patients admitted our department during the period from March, 1981 to February, 1983. The following results were obtained: 1. The results of chemical analysis of 100 urinary calculi revealed calcium oxalate phosphate in 43%, calcium oxalate in 19%, calcium phosphate in 15%, ammonium phosphate in 12%, carbonate calcium oxalate phosphate in 7%, uric acid in 2%, acid + calcium phosphate in 2%. 2. 40 of 100 patients with urinary stones showed bacteriuria and Staphylococcus epidermidis was the most frequent organism. 3. The causative diseases of the urinary stones were renal tuberculosis 4 cases, neurogenic bladder in 4 cases, urethral stricture in 3 cases, BPH in 1 case and hyperparathyroidism in 1 case. 4. The incidence of high urinary calcium amount was greater in lithiasis group(43%) than in control group(17%) The incidence of high urinary calcium amount in lithiasis group was as following order: calcium oxalate phosphate in 55.8%, calcium phosphate in 46.7%, calcium in 42.1% and ammonium phosphate in 28%.
Ammonium Compounds ; Bacteriuria ; Calcium ; Calcium Oxalate ; Carbon ; Humans ; Hyperparathyroidism ; Incidence ; Lithiasis ; Staphylococcus epidermidis ; Tuberculosis, Renal ; Urethral Stricture ; Uric Acid ; Urinary Bladder, Neurogenic ; Urinary Calculi*

PURPOSE: We compared the clinicopathologic effects of TTT between pigmented and albino rabbits. METHODS: TTT was delivered using infrared diode laser at 810 nm(Iris Medical Instrument, Mountain Veiw, CA, USA) and applied with spot size of 3 mm, duration of 60 seconds. At 1 week and 4 weeks after TTT, fundus photographs and simultaneous FAG/ICG angiogram were taken with SLO(Scanning Laser Ophthalmolscopy, Rodenstock, Munish, Germany). Light and electron microscopic examination were performed. RESULTS: In pigmented rabbits, visible funduscopic change was visible even with minimal power setting(100 mW). Obliteration of choroidal vessels was observed on ICG angiogram. In microscopic examination, entire layers of neural retina, retinal pigment epithelial cells, and deep choroid were severely damaged at the center of treated fields. Whereas, in albino rabbits fundus changes were not observed at any power setting. However, focal thrombosis at margin of lesion was identified on ICG angiogram after power of 300 mW. In microscopic examination, tissue damage was developed up to 600 mW and the lesion extended into the superficial choroid posteriorly and outer neural retina anterioly. CONCLUSIONS: The effect of TTT was increased with fundus pigmentation. Clinically we should adjust TTT power setting according to the amount of melanin pigmentation in the fundus.
Choroid ; Epithelial Cells ; Lasers, Semiconductor ; Melanins ; Pigmentation ; Rabbits ; Retina* ; Retinaldehyde ; Thrombosis