No Abstract Available.
Retinal Detachment* ; Retinaldehyde*

No abstract available.
Humans ; Kidney Failure, Chronic* ; Kidney Transplantation* ; Thyroid Gland*

No abstract available.
Humans ; Kidney Failure, Chronic* ; Kidney Transplantation* ; Thyroid Gland*

We have encountered a rare case of erythema nodosum-like leukemia cutis associated with acute myelocytic leukemia(AML) in a 57-year-old male. He was in good health until about 2 weeks prior to admission, when the systemic symptoms of high fever, anorexia, general weakness and malaise, and subcutaneous nodules developed. The nodules were multiple, red and noted bilaterally on the pretibial areas. Histological findings of his skin lesions showed diffuse cellular infiltrates intermingled with leukemic cells predominantly involving the adipose tissues. The cells displayed negative stainirig to antibodies CD3 and CD20, but positive staining to LCA. The diagnosis of AML(M4) was made by blood and bone marrow studies. He had a rapid downhill course and was discharged after 2 weeks of admission, with no anti-cancer chemotherapy.
Anorexia ; Antibodies ; Bone Marrow ; Diagnosis ; Drug Therapy ; Erythema* ; Fever ; Humans ; Leukemia* ; Leukemia, Myeloid, Acute ; Male ; Middle Aged ; Skin

Extravasation of toxic chemotherapeutic 'agents cause severe skin ulceration and necrosis which often need secondary surgical intervention. Still, there were not established antidote agent in case of extravasation with mitomycin-c. Dimethyl sulfoxide is known as an effective chemical scavenger of toxic hydroxyl free radical and sodium thiosulfate also was demonstrated significant protector from mitomycin-c induced ulceration by a few experimental studies. Author investigated necrotic area of mitomycin-c injected site and compare to the effectiveness of topical treatment with dimethyl sulfoxide and intradermal injection of sodium thiosulfate according to starting times, forty five mice were divided into 3 groups. Control group(n=5) had no treatment after subcutaneous injection of mitomycin-c. Experimental group I and 11 were 20 mice treated dimethyl sulfoxide and sodium.
Animals ; Dimethyl Sulfoxide ; Injections, Intradermal ; Injections, Subcutaneous ; Mice ; Mitomycin* ; Necrosis* ; Skin Ulcer ; Sodium* ; Ulcer

We have analyzed 100 urinary calculi by chemical analysis, which obtained from the patients admitted our department during the period from March, 1981 to February, 1983. The following results were obtained: 1. The results of chemical analysis of 100 urinary calculi revealed calcium oxalate phosphate in 43%, calcium oxalate in 19%, calcium phosphate in 15%, ammonium phosphate in 12%, carbonate calcium oxalate phosphate in 7%, uric acid in 2%, acid + calcium phosphate in 2%. 2. 40 of 100 patients with urinary stones showed bacteriuria and Staphylococcus epidermidis was the most frequent organism. 3. The causative diseases of the urinary stones were renal tuberculosis 4 cases, neurogenic bladder in 4 cases, urethral stricture in 3 cases, BPH in 1 case and hyperparathyroidism in 1 case. 4. The incidence of high urinary calcium amount was greater in lithiasis group(43%) than in control group(17%) The incidence of high urinary calcium amount in lithiasis group was as following order: calcium oxalate phosphate in 55.8%, calcium phosphate in 46.7%, calcium in 42.1% and ammonium phosphate in 28%.
Ammonium Compounds ; Bacteriuria ; Calcium ; Calcium Oxalate ; Carbon ; Humans ; Hyperparathyroidism ; Incidence ; Lithiasis ; Staphylococcus epidermidis ; Tuberculosis, Renal ; Urethral Stricture ; Uric Acid ; Urinary Bladder, Neurogenic ; Urinary Calculi*

PURPOSE: There were many studies on the distributions of the retinal ganglion cells(RGC) in the experimental model of the retinal ischemia. RGC was known to be more sensitive to the ischemic injury than the other types of the retinal cells. So, we would identify the changes of the retinal ganglion cell morphologies and distribution after the iatrogenic retinal ischemia induced by intraocular pressure(IOP) elevation. METHODS: Eight pigmented and six white rabbits were used and retinal ischemia was induced by increasing IOP higher than 120 mmHg for 60 minutes. Electroretinogram were recorded at 6 days or 13 days, and histologic findings were observed at 7 or 14 days. RESULTS: After 7 days, RGC densities decreased, cytoplasmic staining disappeared, and the intranuclear hyperpigmentation was noted. RGC densities decreased significantly at 14 days. In the vertical retinal section, some flattening of retinal ganglion cell layer and inner plexiform layer was observed. Changes in the cellular morphologies were prominent. CONCLUSIONS: It may be more appropriate to examine both the retinal whole-mount and the vertical tissue section for the estimatation of the changes of retinal ganglion cell layer in the pressure-induced retinal ischemia.
Cytoplasm ; Ganglion Cysts* ; Hyperpigmentation ; Ischemia ; Models, Theoretical ; Rabbits ; Retina* ; Retinal Ganglion Cells ; Retinaldehyde*

PURPOSE: We compared the clinicopathologic effects of TTT between pigmented and albino rabbits. METHODS: TTT was delivered using infrared diode laser at 810 nm(Iris Medical Instrument, Mountain Veiw, CA, USA) and applied with spot size of 3 mm, duration of 60 seconds. At 1 week and 4 weeks after TTT, fundus photographs and simultaneous FAG/ICG angiogram were taken with SLO(Scanning Laser Ophthalmolscopy, Rodenstock, Munish, Germany). Light and electron microscopic examination were performed. RESULTS: In pigmented rabbits, visible funduscopic change was visible even with minimal power setting(100 mW). Obliteration of choroidal vessels was observed on ICG angiogram. In microscopic examination, entire layers of neural retina, retinal pigment epithelial cells, and deep choroid were severely damaged at the center of treated fields. Whereas, in albino rabbits fundus changes were not observed at any power setting. However, focal thrombosis at margin of lesion was identified on ICG angiogram after power of 300 mW. In microscopic examination, tissue damage was developed up to 600 mW and the lesion extended into the superficial choroid posteriorly and outer neural retina anterioly. CONCLUSIONS: The effect of TTT was increased with fundus pigmentation. Clinically we should adjust TTT power setting according to the amount of melanin pigmentation in the fundus.
Choroid ; Epithelial Cells ; Lasers, Semiconductor ; Melanins ; Pigmentation ; Rabbits ; Retina* ; Retinaldehyde ; Thrombosis

In the recent 2 years, we performed 116 Foley catheter-tip(48 cases of latex, 35 cases of 100% silicone, 33 cases of Silastic) cultures from the male patients who did not have lower urinary tract infection before catheterization. The following result were obtained: 1. The overall positive culture rate of rather-tip culture was 35.3%, and the positive culture rate of urine aspirated from proximal catheter wall just before removal of catheter was 20.6%. 2. The most common microorganism was E-coli in 29.3% and followed by Proteus spp. in 14.7%, Pseudomonas aeruginosa in 12.2%, Klebsiella pneumoniae in 9.8%, Staphylococcus aureus in 7.3%, Candida tropical in 7.3% in orders. 3. In comparison with duration of catheterization, the positive culture rates of catheter-tip of 3 different materials removed within one day were similarly low from 0 th 12%. However, the positive culture rate was much increased in latex-tip (70%) than silicone-tip (23%) and Silastic-tip (14.3%) which were removed between 2 to 4 days. More than 5 days of indwelling catheterization, the positive culture rates were latex-tip in 100%, silicone-tip in 47% and Silastic-tip in 57.1%.
Candida ; Catheterization ; Catheters* ; Catheters, Indwelling ; Humans ; Klebsiella pneumoniae ; Latex ; Male ; Proteus ; Pseudomonas aeruginosa ; Silicones ; Staphylococcus aureus ; Urinary Tract Infections

No abstract available.
Pregnancy*