1.Two Cases of Multicystic Encephalomalacia in a Surviving Co-twin with One Intrauterine Fetal Death.
Tae Bok SONG ; Young Youn CHOI ; Tae Hyung CHO ; Ji Sun KANG ; Chang Yee CHO
Korean Journal of Perinatology 1998;9(3):314-319
Various anatomical defects have been described in the surviving co-twin who had stillborn, macerated monozygotic co-twin with disseminated intravascular coagulation. The suggested mechanism was the transfer of emboli or thromboplastic materials of dead fetus to co-twin through placental vascular anastomoses. Multicystic encephalomalacia is the condition defined anatomically by the presence of multiple cavities in the great part of both cerebral hemispheres. The most common pathogenesis is circulatory disturbance caused by neonatal asphyxia during the perinatal period. We experienced two cases of monozygotic twin with deceased co-twin at 26 weeks, 33 weeks of gestation and confirmed the diffuse multicystic encephalomalacia by cranial ultrasonography and MRI in a surviving co-twin. Only one patient has been followed who showed spastic cerebral palsy and severe mental retardation. We report two cases of multicystic encephalomalacia in a surviring co-twin with a intrauterine fetal death and its related literatures.
Asphyxia
;
Cerebral Palsy
;
Cerebrum
;
Disseminated Intravascular Coagulation
;
Encephalomalacia*
;
Fetal Death*
;
Fetus
;
Humans
;
Intellectual Disability
;
Magnetic Resonance Imaging
;
Pregnancy
;
Pregnancy, Twin
;
Twins, Monozygotic
;
Ultrasonography
3.The antitumor effect of various cytokines on human neuroblastoma cell lines SK-N-SH, IMR-32, and SK-N-MC.
Tae Sook HWANG ; Hyung Geun SONG ; Seong Hoe PARK ; Eui Keun HAM
Journal of the Korean Cancer Association 1992;24(1):35-46
No abstract available.
Cell Line*
;
Cytokines*
;
Humans*
;
Neuroblastoma*
4.Secondary Biliary Cirrhosis in A Case with Intraductal Growth of Hepatocellular Carcinoma.
Hyung Geun SONG ; Yong Il KIM ; Chung Yong KIM ; Soo Tae KIM
Korean Journal of Pathology 1987;21(3):185-191
A case of hepatocellular carcinoma (HCC) complicating with secondary biliary cirrhosis due to intrahepatic bile duct growth of the tumor is presented. The patient was 34 years-old male who had been suffered from right upper quadrant pain with intermittent fluctuating jaundice for 4 months. Left lobectomy specimen contained a single, 4 cm sized, relatively well circumscribed and partly protruding nodular HCC in the medial seqment of left lobe. It compressed the left hepatic duct, and the intra and extra-hepatic ducts were completely plugged with tumor casts (extending to the common bile duct at the operating table). Remaining hepatic parenclyma was the seat of advanced secondary biliary cirrhosis in which were abundance of HBsAg-containing hepatocytes possibily representing a HBsAg carrier status. Biliary cirrhosis in HCC is an extremely rare manifestation, reflecting the delayed adequate clinical procedure by unusual pattern of obstructive jaundice. In such a case presenting as persisting and fluctuating obstructive jaundice in HCC, an intrabile duct tumor growth should be suspected.
Male
;
Humans
;
Carcinoma, Hepatocellular
5.Production of monoclona antibody to infectious bursal disease virus as a diagnostic methods.
Hyung Kwan JANG ; Jai Hong KIM ; Chang Seon SONG ; Soon Jae KIM ; Tae Jong KIM
Journal of the Korean Society of Virology 1993;23(2):171-182
No abstract available.
Infectious bursal disease virus*
6.A Case of Hepatopulmonary Syndrome Diagnosed by 99mTc - MAA Perfusion Lung Scan.
Hyung Tae OH ; Moo Yong LEE ; Il Han SONG ; Seok Gun PARK
Korean Journal of Nuclear Medicine 2002;36(3):203-208
No abstract available.
Hepatopulmonary Syndrome*
;
Lung*
;
Perfusion*
7.The Effect of Ultraviolet B Irradiation on the Skin Barrier Function in Hairless Mice.
Dou Hee YOON ; Hyung Ok KIM ; Tae Yoon KIM ; Chung Won KIM ; Kyae Yong SONG
Korean Journal of Dermatology 1995;33(4):669-678
BACKGROUND: Stratum corneum lipids serve as a water retainer as well as permeability barrier by forming a multi-lamellae structure in the stratum corneum. The major constituent of these lipids, ceramides, have been shown to be predominantly associated with both functions. OBJECTIVE: Exposure of human epidermis to ultraviolet(UV) irradiation leads to changes in the physiologic and biochemical features of the skin. In order to investigate the effect of UVB irradiation on the skin barrier function in hairless mice, transepidermal water loss (TEWL) and lipid composition of stratum corneum were evaluated in hairless mice. METHODS: Hairless mice were irradiated 3 times weekly for 3 weeks with suberythemal dose (0.6MED, Group I) and minimal erythemal dose(MED), Group II) of UB. The mice of Group III received high dose of UVB(3MED) on the back in a single exposure. The control was Group IV. TEWL measured by evaporimeter and lipid composition of stratum corneum appraised by high performance thin layer chromatography(HPTLC) were evaluated weekly for 3 weeks. RESULTS: 1. Each time it was measured, the values of TEWL in group I were lower than group IV, but the difference was not significant. The peak value of TEWL in group II was 8.2+/-1.56 g/cm/h on the 7th day. The increase in TEWL was markedly significant at this point(P<0.001). Although the values of TEWL on the 14th and 21th day in group E increased compared with those of the control group, the significance of the values decreased (P<0.05). 2. The peak value of TEWL in group III was 9.88+/-1.13 g/cm/h on the 2nd day, showed a markedly significant increase compared with that of the control group(P<0.001). The values of TEWL decreased to the level of the control group on the 14th day. 3. The lipid(cholesterol sulfate, ceramide and neutral lipid) and total lipid mass in group 1 were insignificantly larger than that of the group IV measured each time. On the 7th and 14th day, the amount of each three lipid and total lipid mass significantly increased (P<0.05). On the 21th day, the amount of ceramide and neutral lipid showed a significant increase(P<0.05), furthermore the total lipid mass increased pronouncedly(P<0.01) in group II. 4. The amount of the 3 kinds of lipid and total lipid mass in group III significantly increased compared with those of the control group on the 2nd day(P<0.05). After the 7th day, no significant difference of the lipid mass except neutral lipid compared with that of the control group was seen. Comparing the 2nd and 14th day, there was a significant decrease in the amount of ceramide and total lipid mass(P<0.05) CONCLUSION: These results results suggest that considerable amount of UVB irradiation given in single or repeated exposure causes the disruption of skin barrier function, but a compensatory increase of skin lipid, especially ceramide, protests it from further damage and also improves skin barrier function.
Animals
;
Ceramides
;
Epidermis
;
Humans
;
Mice
;
Mice, Hairless*
;
Permeability
;
Skin*
8.The Ultrastructure of Tongue Mast Cells in Bombina orientalis.
Chang Ho SONG ; Hyung Tae KIM ; Ok Hee CHAE ; Sun Ok LEE ; Moo Sam LEE
Korean Journal of Anatomy 1997;30(1):29-34
This study was carried out to observe the ultrastructure of tongue mast cells in frog, Bombina orientalis. In the light microscopy, mast cells were round, oval, spindle-like and irregular shape and occasionally had one or more tail-like long cytoplasmic processes. Mast cells had many red granules stained with toluidine blue in the cytoplasm. In the electron microscopy, mast cells had membrane-bounded granules and poorly developed organelles. The granules were composed of two parts, low and dense electron density. In high magnification the dense part in the middle region of granule had honey comb-like crystalline structure.
Anura*
;
Crystallins
;
Cytoplasm
;
Honey
;
Mast Cells*
;
Microscopy
;
Microscopy, Electron
;
Organelles
;
Tolonium Chloride
;
Tongue*
9.Atrial Morphology Related to Secretory Function and Transport of Metabolites : I. Fenestrations of Basal Lamina in Rat Atrial Endocardium.
Moo Sam LEE ; Chang Ho SONG ; Hyung Tae KIM ; Gyung Woo JO ; Chang Hyun LEE
Korean Journal of Anatomy 1997;30(2):191-198
It was well known that atrial myocytes systhesize atrial natriuretic peptide[ANP], and secrete it into the atrial lumen through the atrial endocardium. But the mechanism for regulation of ANP secretion has not been clearly elucidated, because there was little information of the atrial morphology concerning basal lamina. Basal lamina is surmised as one of barriers that control the movement of ANP, a large molecule. This study was attempted to elucidate the morphological characteristics of basal lamina and connective tissue fibers of atrial endocardial layer by scanning electron microscopy. Basal lamina was exposed by removal of the overlying endothelium. This was achieved by using OsO4 maceration, immersion in aqueous boric acid or EDTA treatment. After removal of the endothelial cell, the specimens were exposed to ultrasonic vibration in case of need. The external surface of basal lamina showed a fairly smooth appearance on the whole, although a few irregular folds are often encountered. Fenestrations, 0.1-1 micrometer in diameter, were randomly observed on the basal lamina, and they were circular to oval in shape. Margin of fenestrations was somewhat distinct and some was divided into two parts by linear structures. The structural differences of fenestrations between right and left atria were not found. The fibroreticular lamina under the basal lamina was revealed by removal of the endothelial cells and their basal lamina. This layer was consisted of interwoven fine fibers. These fine fibers were repeatedly divided and fused, forming reticular network. Some fine fibers connected with basal lamina. Some connective tissue fibers below fibroreticular layer were collected into thick bundles running parallel to myocytes. Above results may serve as a basis for the physiological and morphological studies of atrium.
Animals
;
Atrial Natriuretic Factor
;
Basement Membrane*
;
Connective Tissue
;
Edetic Acid
;
Endocardium*
;
Endothelial Cells
;
Endothelium
;
Immersion
;
Microscopy, Electron, Scanning
;
Muscle Cells
;
Rats*
;
Running
;
Ultrasonics
;
Vibration
10.Effects of middle ear and temporal bone pathology on bone conduction hearing level in chronic otitis media.
Song Ho KANG ; In Young KWAK ; Chul Won PARK ; Hyung Seok LEE ; Kyung Sung AHN ; Kyung TAE
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(5):694-701
No abstract available.
Bone Conduction*
;
Ear, Middle*
;
Otitis Media*
;
Otitis*
;
Pathology*
;
Temporal Bone*