1.Analysis of the functional domain of the hepatitis B virus X gene product fused to the GAL4 binding domain.
Byung Hyune CHOI ; Cheol Yong CHOI ; Geon Tae PARK ; Hyung Mo RHO
Journal of the Korean Society of Virology 1993;23(1):1-10
No abstract available.
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
2.A Case of Paratesticular Embryonal Rhabdomyosarcoma.
Sinn JEONG ; Won Joon BHANG ; Tae Hyung RHO ; Young Chul YOON ; Soo Chan KIM ; Sam Keuk NAM
Korean Journal of Urology 2000;41(11):1415-1417
No abstract available.
Rhabdomyosarcoma, Embryonal*
3.The Effect of the Treatment of Prostatitis on the Serum Prostate Specific Antigen Levels and the Frequency of Prostatic Biopsies.
Tae Hyung RHO ; Jeong Gu LEE ; Sam Keuk NAM
Korean Journal of Urology 2002;43(10):847-851
PURPOSE: We attempted to identify the prostatitis in men with elevated serum prostate specific antigen (PSA) levels, and also determined whether treatment with antibiotics lowers serum PSA, resulting in decreases of the frequency of prostatic biopsies. MATERIALS AND METHODS: Men with lower urinary tract symptoms, and serum PSA greater than 4ng/ml, were evaluated for the presence of prostatitis. Prostatitis was defined as over 20 white blood cells in expressed prostatic secretions. Patients with prostatitis were treated with a 4-week course of antibiotics. Patient without signs of prostatitis underwent transrectal biopsies. PSA blood tests and prostatic massages were repeated 4 weeks later. Patients with PSA levels greater than 25ng/ml were excluded. RESULTS: Of the 49 patients with elevated PSA levels (with a mean PSA level of 9.26ng/ml), 29 (59%) had the laboratory signs of prostatitis. In 18 patients (62%) with prostatitis, the serum PSA level decreased to below 4ng/ml (mean 2.73ng/ml) after treatment. The remaining 11 patients with prostatitis, and the 20 patients without, underwent sextant transrectal ultrasound guided biopsies; which resulted in pathologic confirmation of prostate cancer in 3 out of the 11 patients with prostatitis, and in 4 (20%) out of the 20 patients without. Screening for prostatitis decreased the frequency of a prostatic biopsy by 32.7%. CONCLUSIONS: In over half of the patients with elevated serum PSA levels, the clinical evaluation revealed evidence of prostatitis. The treatment of prostatitis in this study decreased prostate biopsies by 32.7%. We suggest that screening for prostatitis in patients with elevated PSA levels, and it subsequent treatment can decrease the percentage of negative biopsies.
Anti-Bacterial Agents
;
Biopsy*
;
Hematologic Tests
;
Humans
;
Leukocytes
;
Lower Urinary Tract Symptoms
;
Male
;
Mass Screening
;
Prostate*
;
Prostate-Specific Antigen*
;
Prostatic Neoplasms
;
Prostatitis*
;
Ultrasonography
4.Transesophageal Atrial Pacing in Atrial Flutter.
Tae Ho RHO ; Man Young LEE ; In Soo PARK ; Jong Jin KIM ; Ho Joong YOON ; Kie Bae SEUNG ; Jae Hyung KIM ; Kyu Bo CHOI ; Soon Jo HONG
Korean Circulation Journal 1995;25(1):29-35
Atrial flutter, a common rhythm disturbance, was first described over 80 years ago. Despite extensive investigations, several important issues remain unresolved concerning its exact mechanism and management. Present therapeutic strategies often appear effective to prevent and terminate atrial flutter. However, controlled trial and definitive studies comparing the various treatment options are surprisingly scarce. Here we report on a study of 9 episodes of spontaneous atrial flutter(AF)(flutter wave cycle length 224+/-39 msec) treatedd by transesophageal atrial pacing(TAP) in 9 patients(7 men and 2 women; mean age 56.9 yrs). TAP was effective in 5 patients : sinus rhythm resumption was immediate in 3 patients and followed a short period of atrial fibrillation in 2 patients. TAP was unsuccessful in 4 patients. All the patients tolerated the procedure well. These data strongly support the immediate first choice use of TAP in AF therapy.
Atrial Fibrillation
;
Atrial Flutter*
;
Female
;
Humans
;
Male
5.A Case of Incessant Ventricular Tachycardia Abolished after Endomyocardial Biopsy.
Man Young LEE ; Jang Seong CHAE ; Gil Hwan LEE ; Dong Heon KANG ; Kie Bae SEUNG ; Tae Ho RHO ; Jae Hyung KIM ; Soon Jo HONG ; Kyu Bo CHOI
Korean Circulation Journal 1996;26(5):1074-1081
Ventricular tachycardia is an important tachyarrhythmia which is encountered commonly in clinical field. The accompanying manifestations could be variable just from palpitation to sudden cardiac death. The classification of this arrhythmia has not completly settled yet, but in a broad way this arrhythmia is classified according to the prescence or abscence or underlying heart disease, especially coronary artery disease. Recently, therapeutic modalities for this arrhythmia have been changed a lot from classical antiarrhythmic drugs to radiofrequency ablation or ICD implantation although there are still some problems to overcome. We experienced a case of 34-year-old female having an incessant ventricular tacycardia which was abolished after endomyocardial biopsy performed to differentiate underlying myocardial pathology.
Adult
;
Anti-Arrhythmia Agents
;
Arrhythmias, Cardiac
;
Biopsy*
;
Catheter Ablation
;
Classification
;
Coronary Artery Disease
;
Death, Sudden, Cardiac
;
Female
;
Heart Diseases
;
Humans
;
Pathology
;
Tachycardia
;
Tachycardia, Ventricular*
6.A Study on Neurosis According to Experience of Sexual Abuse among Female High School Students in Tasegu.
Hyung Bae PARK ; Jin Sung KIM ; Sang Ruyl JANG ; Tae Yong RHO ; Hye Soo SUH ; Chang Su KIM ; Kwang Hun LEE
Yeungnam University Journal of Medicine 1995;12(1):113-123
1) The sexual abuse victim group showed significantly higher neurotic traits of Free floating anxiety (p<0. 05), Phobic(p<0.01), Obsession(p<0.01), Somatic(p<0.05), Depression(p<0.01) than the control group. 2) The Neurotic traits of Somatic(p<0.01), Depression(p<0.01), Hysteric(p<0.01) were higher in the multiple-abused than the single-abused. 3) When the duration of being abused was concerned, subjects with more than 1 year duration had significantly higher neurotic traits of Obsession(p<0.05), Somatic(p<0.05), Depression(p<0.05) than subjects with less than 1 year duration. 4) The neurotic traits of Phobic, Somatic, Depression were significantly higher in the subjects with higher intensity of sexual abuse than with lower intensity. 5) Among 68 victims, 31 girls(45%) were assaulted by strangers, 10(14%) were by relatives, 7(10.3%) were by siblings, 6(8.8%) were by neihbors. Among them, 34 girls(50%) bad counselling or psychotherapy and the people to whom they had sought for help were friends(23 girls ; 68%), parents (7 girls ; 11.7%) and mental health professonals (2 girls ; 5.9%).
Anxiety
;
Daegu*
;
Depression
;
Female*
;
Humans
;
Mental Health
;
Parents
;
Psychotherapy
;
Sex Offenses*
;
Siblings
7.Radiofrequency Catheter Ablation in Patients with Paroxysmal Supraventricular Tachycardia : The Initial Experience and The Extent of Myocardial Damage.
Ji Won PARK ; Ho Joong YOUN ; Wook Sung CHUNG ; Man Young LEE ; Tae Ho RHO ; Jang Seoung CHAE ; Jae Hyung KIM ; Kyu Bo CHOI ; Soon Jo HONG
Korean Circulation Journal 1995;25(3):554-559
BACKGROUND: The catheter ablation usin radiofrequency(RF) energy in patients with atrioventricular nodal reentrant tachycardia(AVNRT) and atrioventricular reentrant tachycardia(AVRT) ahs been proved as a safe and effective nonpharmacologic therapeutic modality. The purpose of our study was to evaluate the success rate and complications of the initial experience and to determine the extent of myocardial damage of RF catheter ablation. METHODS: Electrophysiologic study was performed with the standard technique. Twenty five patinents(M:F=16:9, mean age:42 years old) underwent RF catheter ablation in St. May's Hospital from April to December in 1994. The RF generator in this study was RFG-3D model and catheters were 6F or 7F steerable catheters with 4mm kistal tip. In order to evaluate the extent of myocardial damage the WBC count, LDH, CK, and CK-MB fraction were checked before and after RF catheter ablation and the Tc99m myocardial scintigraphy was performed within 72 hours of the porcedure. RESULTS: Six of twenty five patients had AVNRT, in which the success rate of selective ablation of the slow pathway was 83.8%. Nineteen patients with AVRT had one accessory pathway. The ablation success rate of 14 accessory pathways in left free wall location was 85.7%, and that of 3 in left posteroseptal location was 66.6%. Two right sided accessory pathways were not ablated successfully. The level of CK-MB fraction after ablation was within normal limit. Only one case revealed grade 2 of hot spot in Tc99m myocardial scintigraphy. CONCLUSION: The RF catheter ablation in patients with AVNRT and AVRT is a safe and effective nonpharmacologic therapeutic modality. But right sided accessory pathways are more difficult to ablate than left sided accessory pathways, requiring more experiences and better technique. The extent of myocardial damage after RF catheter ablation reveals relatively minimal by cardiac enzyme study and Tc99mmyocardial scintigraphy.
Catheter Ablation*
;
Catheters
;
Humans
;
Myocardial Perfusion Imaging
;
Radionuclide Imaging
;
Tachycardia, Supraventricular*
8.Changes of Monophasic Action Potentials during PTCA.
Ho Joong YOUN ; Wook Sung CHUNG ; Tae Ho RHO ; In Soo PARK ; Chul Min KIM ; Jae Hyung KIM ; Kyu Bo CHOI ; Soon Jo HONG
Korean Circulation Journal 1995;25(2):483-491
BACKGROUND: Monophasic Action Potential(MAP) recording using contact electrode is very sensitive method to detect the ischemic changes of myocardium. The purpose of this study were to investigate changes of MAP during percutaneous transluminal coronary angioplasty(PTCA) and to evaluate through MAP whether or not a brief episode of ischemia influenced on subsequent ischemic episode during PTCA. Method: MAPs using endocardial contact electrode were recorded dbefore, during the fitst and second inflation and 3 min after PTCA in 7 patients undergoing PTCA. RESULTS: 1) MAP amplitude significantly decreased to 79.1+/-11.0% during the first inflation(p<0.05) and to 86.3+/-9.0% during the second inflation(p<0.05) and recovered to 92.7+/-3.7% at 3 min after PTCA. 2) MAP duration to 90% repolarization(MAPD 90) significantly decreased to 91.4+/-5.1% during the first inflation(p<0.05) and to 95.3+/-3.5% dudring second inflation(p<0.05) and recovered to 97.3+/-2.8% at 3 min after PTCA. 3) Double prodducts showed no significant difference between the first and second inflation. 4) The changes of MAP amplitude and MAP duration during the second inflation was significantly lower than that recorded during the first inflation. CONCLUSION: MAP recording using endocardial contact electode may be safe and very sensitive method to detect the ischemic changes of human endocardium and the lessened MAP changes during the second inflation supports the concept of preconditioning ischemia.
Action Potentials*
;
Electrodes
;
Endocardium
;
Humans
;
Inflation, Economic
;
Ischemia
;
Myocardium
9.A Case of Retroperitoneal Teratoma in an Adult.
Won Joon BHANG ; Tae Hyung RHO ; Young Chul YOON ; Ji Yong KIM ; Soon Chan KIM ; Sam Keuk NAM ; Hyo Jin LEE
Korean Journal of Urology 2001;42(7):767-769
The teratoma is made up of a variety of parenchymal cell types representative of more than one germ layer. Retroperitoneal teratoma is an uncommon neoplasm which occurs in only 10% of all retroperitoneal primary neoplasm. Primary retroperitoneal teratoma has been rarely seen in adults and 3 cases has been reported in Korea. Recently we experienced a case of retroperitoneal teratoma, which was suspected by clinical investigation and confirmed by exploration and microscopic examination. CT scan is very useful in differential diagnosis of this rare tumor. We report a case of retroperitoneal teratoma in 22 year old young woman.
Adult*
;
Diagnosis, Differential
;
Female
;
Germ Layers
;
Humans
;
Korea
;
Teratoma*
;
Tomography, X-Ray Computed
;
Young Adult
10.A study on the characteristics and the pathogenesis of hemodialy sis ascites . - Hemodialy sis adequacy ( Kt / V urea ) and serum ascites albumin gradient ( SAAG ) -.
Kyu Yong PARK ; Chung Mi YOUK ; Ja Ryong KOO ; Gheun Ho KIM ; Rho Won CHUN ; Hyung Jik KIM ; Dong Wan CHAE ; Jung Woo NOH ; Ik YANG ; Hyoun Tae KIM
Korean Journal of Medicine 2000;59(3):283-289
BACKGROUND: The aim of this study was to characterize the nature and elucidate the pathogenesis of hemodialysis ascites(HA), especially with regard to the levels of Serum Ascites Albumin radient(SAAG) and the degrees of hemodialysis adequacy(Kt/Vurea). METHODS: In the study group, seven cases of HA which had developed in 6 patients from Feb. 1997 through July 1998 were included. In the control group, 24 cases which had not developed HA were included. The study design was a retrospective. Analysis of ascites on WBC, total protein and albumin, cytology, ADA(Adenosine deaminase), osmolality, SAAG and routine work-up were performed in HA group. Serum total protein and albumin, C-reactive protein(CRP), osmolality, and routine liver function test were also checked. Kt/Vurea and weekly Kt/Vurea were calculated in both group. In statistical analyses, t-test and chi-square test were used. RESULTS: Mean SAAG of HA was >1.1(1.49+/-0.40) gm/dL, and mean concentration of total protein of HA was >2.5(4.26+/-0.58) gm/dL. The mean of weekly Kt/Vurea of patients with HA(2.61+/-0.85) was significantly lower than that of patients without HA(3.48+/-0.90)(p<0.05). Positive ratio of CRP in patients with HA was higher than that of patients without HA(p<0.05). Mean concentration of serum total protein was significantly higher in patients with HA than that of patients without HA but with comparable weekly Kt/Vurea levels(p<0.05). CONCLUSION: It is regarded that the nature of HA is an exudate having high SAAG over 1.1 gm/dL. Low weekly Kt/Vurea is suggested as a cause of HA. Chronic inflammation was also regarded as an important factor causing HA.
Ascites*
;
Exudates and Transudates
;
Humans
;
Inflammation
;
Liver Function Tests
;
Osmolar Concentration
;
Renal Dialysis
;
Retrospective Studies
;
Urea*