1.Pathophysiology of tuberculosis.
Tuberculosis and Respiratory Diseases 1991;38(4):331-339
No abstract available.
Tuberculosis*
3.Biological detection of enterotoxigenic E. coli.
Jeong Kyu PARK ; Seong Kyu PARK ; Hwa Jung KIM ; Tae Hyun PAIK ; Tae Kyung CHOI
Journal of the Korean Society for Microbiology 1991;26(3):215-222
No abstract available.
Enterotoxigenic Escherichia coli*
4.Lymphocyte proliferation and antibody response against 30-kDa protein antigen of mycobacterium tuberculosis.
Tae Hyun PAIK ; Bong Kyu LEE ; Hwa Jung KIM ; Eun Gyeong JO ; Tae Kyung CHOI
Journal of the Korean Society for Microbiology 1992;27(3):253-268
No abstract available.
Antibody Formation*
;
Lymphocytes*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
5.Purification and immunochemical charaterization of alpha-antigen from the culture filtrate of mycobacterium tuberculosis.
Seok Kwun KIM ; Tae Hyun PAIK ; Hwa Jung KIM ; Jeong Kyu PARK ; Tae Kyung CHOI
Journal of the Korean Society for Microbiology 1991;26(1):45-60
No abstract available.
Mycobacterium tuberculosis*
;
Mycobacterium*
6.Determination of antibody activities of alpha- and beta-protein antigens of mycobacterium tuberculosis in cerebrospinal fluid by ELISA for the diagnosis of tuberculous meningitis.
Kyung Suk LEE ; Tae Hyun PAIK ; Hwa Jung KIM ; Jeong Kyu PARK ; Tae Kyung CHOI
Journal of the Korean Society for Microbiology 1991;26(1):37-43
No abstract available.
Cerebrospinal Fluid*
;
Diagnosis*
;
Enzyme-Linked Immunosorbent Assay*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Tuberculosis, Meningeal*
7.Detection of mycobacterium tuberculosis in sputum samples by polymerase chain reaction.
Eun Gyeong JO ; Tae Kyung CHOI ; Tae Hyun PAIK ; Jeong Kyu PARK ; Hwa Jung KIM
Journal of the Korean Society for Microbiology 1993;28(2):131-142
No abstract available.
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Polymerase Chain Reaction*
;
Sputum*
8.Purification of 30-kDa and 32 kDa protein antigens from mycobacterium tuberculosis and activation of human monocytes by lymphokines.
Tae Kyung CHOI ; Hwa Jung KIM ; Eun Gyeong JO ; Jeong Kyu PARK ; Tae Hyun PAIK
Journal of the Korean Society for Microbiology 1993;28(2):113-130
No abstract available.
Humans*
;
Lymphokines*
;
Monocytes*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
9.Paget's Disease of the Breast.
Journal of the Korean Surgical Society 2001;61(1):40-45
PURPOSE: Paget's disease of the breast (PDB) occurs in approximately 1~3% of all primary breast carcinomas. This study aimed to determine the optimal surgical treatments for PDB in this study. METHODS: The medical records of 16 patients with PDB who had been treated between January 1986 and December 1998 were clinically reviewed retrospectively. RESULTS: 13 patients had nipple changes consistent with clinical Paget' disease (CPD) including 8 who had an associated breast mass, and 5 who had no associated mass. Of the 13 patients with CPD, 12 were treated with a modified radical mastectomy while 1 was treated with a radical mastectomy. Breast cancer (BC) was found in all of 13 patients (100%) with CPD. The BC was centrally located in 46% of patients including 38% in CPD associated with the mass and 60% in CPD not associated with the mass. Out of 8 CPD patients associated with the mass, 7 (88%) had invasive cancer, 1 (12%) had a ductal carcinoma in situ (DCIS), and 2 (25%) had pathologic axillary nodes (PAN). The 5 year survival rate was 87.5%. Of the 5 CPD patients not associated with the mass, 4 (80%) had an invasive cancer, 1 (20%) had a DCIS and none had PAN. Their 5 year survival rate is 100%. CONCLUSION: All the patients with CPD had an associated BC. BC is more frequently centrally located in the CPD not associated with the mass (60%) than those associated with the mass (38%). Contrarily, the BC in CPD that was not associated with the mass was located more peripherally (40%). Therefore, the treatment of patients with CPD must be individualized in order to avoid under or overtreatment.
Breast
;
Breast Neoplasms
;
Carcinoma, Intraductal, Noninfiltrating
;
Humans
;
Mastectomy, Modified Radical
;
Mastectomy, Radical
;
Medical Records
;
Nipples
;
Paget's Disease, Mammary*
;
Retrospective Studies
;
Survival Rate
10.Determination of Anti-tuberculous Antibody Against Triton X-100 Solubilized Protein ( TSP ) Antigen of Mycobacterium tuberculosis in the Sera of Patients with Pulmonary Tuberculosis.
Tae Hyun PAIK ; Jeong Kyu PARK ; Hwa Jung KIM ; Kyung Jin KIM ; Eun Kyeong JO
Journal of the Korean Society for Microbiology 1997;32(1):59-70
Some of the proteins of mycobacteria are preferentially associated with the cell wall and are powerful immunogens, and humoral antibody responses to these mycobacterial antigens may occur in patients with tuberculosis. In this study, Triton X-100 solubilized protein (TSP) antigen was isolated from Mycobacterium tuberculosis H37Rv by overnight shaking with 1% Triton X- 100/PMSF and 10-90% ammonium sulfate precipitation. IgG and IgM antibody levels against TSP, crude protein from the unheated cultrue filtrate (CF#) and 30 kDa antigens were determined in the sera of 80 patients with pulmonary tuberculosis and 99 healthy controls with PPD (+) and (-). High IgG reactivity to TSP and CF antigen was observed in tuberculosis patients. Mean IgG antibody titers against all of three mycobacterial antigens were differed significantly (P<0.01) between patients and controls but IgM showed no difference. By the cut-off value adding 2 standard deviation to the mean absorbance of controls, the sensitivity and specificity of the IgG antibody to TSP antigen were 93.9% and 77.5%. The specificity to TSP antigen was a litttle higher than those obtained by CF and 30 kDa antigen. From the above results, the TSP antigen may be useful for the serodiagnosis of tuberculosis.
Ammonium Sulfate
;
Antibody Formation
;
Cell Wall
;
Humans
;
Immunoglobulin G
;
Immunoglobulin M
;
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Neptune*
;
Octoxynol*
;
Sensitivity and Specificity
;
Serologic Tests
;
Tuberculosis
;
Tuberculosis, Pulmonary*