1.Frequency of Granulocyte-Spedfic Anhgens among Koreans.
Korean Journal of Blood Transfusion 1996;7(1):1-9
Granulocyte-specific antigens, such as NA1, NA2, NBI, NB2, NC1, NDI, NE1, are a group of antigens specifically expresesed only on the granulocytes. Antibodies against these are involved in some clinical disorders such as alloimmune neonatal neutropenia(ANN), autoimmune neutropenia(AIN), and transfusion-related acute lung injury(TRALI). We investigated the frequencies of NA1, NA2, NB1, and Mart antigens among Koreans by the granulocyte indirect immunofluorescence test employing flow cytometry. The subjects were 105 Koreans(male 65, female 40), whose mean age was 31.7+/-8.2 years (range 16~57). The antigen and gene frequencies were as follows, NA1, 0.78, 0.53, NA2, 0.75, 0.50, NB1 0.86, 0.62, and Mart, 1.00, 1.00, respectively. The proportions of NB 1 -positive granulocytes among NB 1-positive individuals were variable(range, 27~100%). Through this study, the authors procured granunlocyte-specifiic antigen papnel, which is essential in the identification of causative antibody(-ies) in immune neutropenias.
Antibodies
;
Female
;
Flow Cytometry
;
Fluorescent Antibody Technique, Indirect
;
Gene Frequency
;
Granulocytes
;
Humans
;
Lung
;
Neutropenia
2.Diagnostic significance of serum A and B glycosyltransferase assay for the classification of ABO subgroups.
Kyou Sup HAN ; Tae Hee HAN ; Dong Hee WHANG ; Bok Yeon HAN ; Hyun Jin JUNG
Journal of the Korean Society for Microbiology 1999;34(1):27-34
BACKGROUND: A and B transferase are glycosyltransferase that transfer N-acetylgalactosamine and D- galactose to H antigen, respectively and lead to the expression of A and B phenotypes in ABO blood group system. Reduced or no activities of serum A and B transferase were observed in some A and B subgroup individuals. Determining the activities of serum A and B transferase can be useful in discriminating rare A and B subgroups. MATERIALS AND METHODS: ABO typing, saliva test, adsorption elution test and serum transferase assay were performed on samples from 12 individuals showing ABO discrepancy or weakened cell typing reactions which were referred to the Seoul National University Hospital to confirm their ABO blood types. Serum transferase activity was assayed by determining the ability of serum to convert group 0 RBCs into A or B cells. RESULTS: Determination of serum ABO transferase activity was useful in the identification of Ael (3 cases), B. (2 cases), Bm (1 case), Am (1 case), Bx (1 case), 0 with weakened anti-A or anti-B (3 cases), and A without anti-B due to hypogammaglobulinemia (1 case). CONCLUSION: Determining serum A and B glycosyltransferase activity was proven to be a simple and useful tool for the classification of several ABO subgroups.(Korean J Blood Transfusion 10(1): 27-33, 1999)
ABO Blood-Group System
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Adsorption
;
Agammaglobulinemia
;
B-Lymphocytes
;
Blood Transfusion
;
Classification*
;
Galactose
;
Phenotype
;
Saliva
;
Seoul
;
Transferases
5.A Study of Genetic Inheritance of Bromidrosis.
Han Ho CHU ; Young Tae SEO ; Han Sol LEE ; Yeon Su KIM ; Yoo Hyun BANG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(2):210-214
Bromidrosis is a disorder characterized by rancid body odor which influences a patient's social life and mental health. The therapeutic modalities and the mechanism of bromidrosis have been carefully studied, however, there have been few reports about the genetic inheritance of bromidrosis. We investigated the family history of 42 patients who were operated on for bromidrosis and followed up to the third generation in 10 cases. The results were as follows: Results of investigation which were followed up the second generation. The fathers of five patients and the mothers of 11 patients had bromidrosis in 18 male patients. The fathers of six patients and the mothers of 12 patients had bromidrosis in 24 female patients. Thirty-four patient (81.0%) among a total of 42 have a single parent with bromidrosis. Result of investigation which were followed up to the third generation Bromidrosis was occurred in 17 of 42 patients (40.5%) in the second generation, and 18 of 27 patients (66.7%) in the third generation. In one case, a father transmitted bromidrosis to his three sons, and as a result, X-linked inheritance could be ruled out Bromidrosis was not skipped in every generation of all families. We on conclude that bromidrosis is an autosomal dominant inherited disorder.
Fathers
;
Female
;
Genes, X-Linked
;
Humans
;
Male
;
Mental Health
;
Mothers
;
Odors
;
Single Parent
;
Wills*
6.Procedure-Related Complications of Transjugular Intrahepatic Portosystemic Shunt (TIPS) and Its Clinical Significance.
Yong Joo KIM ; Duk Sik KANG ; Hyun Han OH ; Kyung Hwan BYUN ; Tae Gwon KIM
Journal of the Korean Radiological Society 1995;33(1):67-72
PURPOSE: The purpose was to evaluate the procedure-related complications of the TIPS and its clinical significance. MATERIALS AND METHODS: The materials consisted of 52 patients who had 57 TIPS procedures for the management of variceal bleeding due to portal hypertension. To detect the occurrence of complications during transhepatic needle puncture(from hepatic vein to the portal vein), contrast material was injected with the withdrawl of the puncture needle. RESULTS: Procedure-related complications occurred in 28 patients (54%) among 52 patients. The corn lications were biliary tree puncture(15 cases), transperitoneal puncture(14 cases), stent malposition(3 cases) stent migration(1 case), hepatic arteries puncture(1 case), splenic vein perforation(1 case), and paroxysmal tricular tachycardia(1 case). Three patients had acute stent thrombosis with rebleeding immediately after procedure. The procedure was repeated in two patients. One patient was expired due to rebleeding. CONCLUSION: The procedure related complications were clinically insignificant in most instances, when stent thrombosis or proxysmal ventricular tachycardia was developed.
Biliary Tract
;
Esophageal and Gastric Varices
;
Hepatic Artery
;
Hepatic Veins
;
Humans
;
Hypertension, Portal
;
Needles
;
Portasystemic Shunt, Surgical*
;
Punctures
;
Splenic Vein
;
Stents
;
Tachycardia, Ventricular
;
Thrombosis
;
Zea mays
7.A Human case of thelaziasis in Korea.
Sung Tae HONG ; Sang Hyun LEE ; Hoon HAN
The Korean Journal of Parasitology 1985;23(2):324-326
A case of thelaziasis in 36 year-old Korean woman who suffered from foreign body sensation of both eyes and itching of conjuctiva, was reported in August 1984. Four thread-like white worms was removed from cojunctival fornix of both eyes. This is the 12th case of thelaziasis in Korea(summarized from text).
parasitology-helminth-nematoda
;
case report
;
Thelazia callipaeda
;
thelaziasis
8.A study of the low maternal weight gain and risk of preterm delivery.
Tae Hwa KIM ; So Hyun SONG ; Hae Kyeoung HAN ; Suok Jae CHO
Korean Journal of Obstetrics and Gynecology 1993;36(1):24-28
No abstract available.
Weight Gain*
9.Dynamic MR Imaging in gastric Cancer: Comparison Between Precontrast and Postcontrast Images.
Sung Hwan HONG ; Joon Koo HAN ; Tae Kyung KIM ; Kee Hyun CHANG ; Byung Ihn CHOI
Journal of the Korean Society of Magnetic Resonance in Medicine 1997;1(1):130-134
PURPOSE: To analyze contrast-enhancement pattern of stomach cancer on dynamic MRI and to verify the efficacy of intravenous contrast agent in the evaluation of stomach cancer. MATERIALS AND METHODS: Twelve patients with proven stomach cancer underwent dynamic MRI, By using 1.0T scanner, we obtained precontrast FLASH images, and 30, 60, 90 second delay FLASH images after intravenous contrast injection. All patients ingested on liter of water and had intramuscluar injection of Buscopan just before MR study. For quantitative analysis we measured signal to noise ratio (S/N) of stomach cancer on each image, and signal difference to noise ratio (SD/N) between cancer and intraluminal fluid, cancer and the pancreas. For qualitative analysis two radiologists evaluated lesion conspicuity on each image by grading system(grade 0, 1, 2, 3: poor, fair, good, excellent). RESULTS: S/N of stomach cancer increased gradually by time(precontrast, 30, 60, 90 second delay:38.7, 42.5, 57.4, 65.7). SD/N between cancer and intraluminal fluid significantly increased after contrast enhancement(1.24, 25.01, 39.30, 45.89). SD/Ns between cancer and the pancreas were 10.5, 9.33, 9.99, 10.66 respectively. In qualitative analysis, precontrast images were better than postcontrast images for delineation of stomach cancer, Postcontrast images showed clear endo-luminal side of stomach cancer, but outer margin of stomach cancer was more distinct on precontrast images. CONCLUSION: Precontrast MR images are better than postcontrast MR images in the depiction of stomach cancer. Intravenous contrast agent is not imperative in the evaluation of stomach cancer.
Butylscopolammonium Bromide
;
Humans
;
Magnetic Resonance Imaging*
;
Noise
;
Pancreas
;
Signal-To-Noise Ratio
;
Stomach Neoplasms*
;
Water
10.Clinical Observation on Human Rota Virus Gastroenteritis in Infants and Children.
Han Young JEONG ; Gu Seok JUNG ; Sung Won KIM ; Kyung Tae KIM ; Kil Hyun KIM
Journal of the Korean Pediatric Society 1986;29(5):53-60
No abstract available.
Child*
;
Gastroenteritis*
;
Humans*
;
Infant*