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This study was performed to investigate clinical and histopathologic features of steroid acne, which was induced by systemic administration and topical application of corticosteroids. Thirty five cases of steroid acne visited to Department of Dermatology, Hangang Sacred Heart Hospital from September, 1g79 to June, 1984 were analyzed, and the results obtained can be summarized as follows: 1. The peak age of the subjects was third decade(42.9%) with an average age of 30. 1 years, and male to female ratio was l.9: 1,2. The skin lesions had unique clinical features that showed many, uniform sized, erythematous papules and pust;ules. 3 The predilection sites of steroid acne induced by systemic steroid therapy were anterior chest(93.1%), back(44,8%), neck(31.0%), shoulder(31.0%) and face (20.7%) 4 Among thirty five cases of steroid acne, twenty cases were induced by parenteral adrninistration of dexamethasone disodium phosphate(group A), nine cases by oral administration of prednisolone(group B), and six cases by topical application of three kinds of steroid creams(group C). 5. The mean induction time after starting steroid in group A(ll. 3 days) was shorter than those in group B and C(18.9 days and l4.8 days respective)y). The mean total dosage of used steroid in group A was 191. 3mg of dexamethasone disodium phosphate and that in group B was 515. 7mg of prednisolone. On histopathologic findings of twenty two skin biopsy specimens of the three groups, perivascular inflammatory reaction was the most common finding followed by intra-and peri-follicular inflammatory reaction, dermal vascular dilatation, necrosis of follicular epithelium, comedo, intraand periollicular abscess and rupture of follicle.
Abscess ; Acne Vulgaris* ; Administration, Oral ; Adrenal Cortex Hormones ; Biopsy ; Dermatology ; Dexamethasone ; Dilatation ; Epithelium ; Female ; Heart ; Humans ; Male ; Necrosis ; Prednisolone ; Rupture ; Skin

1.Results of observation versus operation for right lower abdominal pain in pediatric patients.

2.Results of observation versus operation for right lower abdominal pain in pediatric patients.

3.Clinical and Histopathologic Study of Steroid Acne.

4.In vitro transposition of Tn5.

5.Clinical analysis of 98 patients undergoing concomitant cholecystectomy and exploration of the common bile duct.

6.A Case of Solitary Nevus Lipomatosus Superficialis with Congenital Onset.

7.A Case of Sparganosis Detected by Ultrasonography in a Patient with Colon Cancer.

8.2 Cases of Prostatic Myosarcoma : Rhabdomyosarcoma andn Leiomyosarcoma.

9.Complete Androgen Insensivity Syndrome in Sisters.

10.Continuous arteriovenous hemofiltration in the treatment of acute renal failure and intractable edema.

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