3.Frozen Section: Application in the Surgical Pathology.
Won Hee CHOI ; Tae Sook LEE ; Suk Jae HONG
Yeungnam University Journal of Medicine 1986;3(1):179-183
The frozen section technique is a means of intraoperative pathological diagnosis, and a procedure of great value to the surgeon. This method should be accurate, rapid and reliable. This method serves useful purposes, such as determining the presence of tumor, its type (especially whether it is benign or malignant), the adequacy of a biopsy of a suspected lesion, and the conditions of the surgical margins. But, it bears many disadvantages, the most of which is the danger of incorrect diagnosis. We studied the indications, the limitations, and the accuracy of the frozen section method and the materials studies was total of frozen section diagnosis of 809 cases was 98.1% with 0.5% of false negative, 0% of false positive 0.5% of incorrect histological diagnosis or grading errors, and 0.9% of deferred cases. The tissues submitted were lymph node, gastrointestinal tract, skin subcutaneous tissues in decreasing oder of frequency. The false positive case is not present, while the false negative cases were 4.
Biopsy
;
Diagnosis
;
Frozen Sections*
;
Gastrointestinal Tract
;
Lymph Nodes
;
Methods
;
Pathology, Surgical*
;
Skin
;
Subcutaneous Tissue
4.A Case of Mucoepidermoid Carcinoma of Parotid Gland Origin.
Dong Sup CHOI ; Tae Ha WOO ; Hong Sang CHIN
Korean Journal of Dermatology 1973;11(3):183-186
Mucoepidermoid earcinoma occurred in about 2% among salivary gland tumor and in about 15% among malignant parotid gland tumor. The tumor occurred usually in elderly persons and arose as innocent-appearing swelling in the parotid gland region with gradual painless enlargement without alarming and it's usual size is less than 2 cm, However, a few of the poorly differentiated neoplasms grew rapidly and were painful and accompanied by facial nerve paralysis in about 15%. But it's prognosis is better than other salivary gland origin. We report a case of typical mucoepidermoid carcinoma of parotid gland origin which is occurred in 15 years old girl. The tumor begins pea sized painless nodule since about 2 years ago, and enlarged gradually to apple size and accompanied by facial nerve paralysis and pain sensation recently. But there was no evidence of tumor in parotid gland itself and no metastasis.
Adolescent
;
Aged
;
Carcinoma, Mucoepidermoid*
;
Facial Nerve
;
Female
;
Humans
;
Neoplasm Metastasis
;
Paralysis
;
Parotid Gland*
;
Peas
;
Prognosis
;
Salivary Glands
;
Sensation
5.The Effect of Incubation Temperature on Susceptibility Test of Dermatophytes to Oral Antifungal Agents.
Tae Hun KWAK ; Jong Soo CHOI ; Ki Hong KIM
Korean Journal of Dermatology 1995;33(2):240-247
BACKGROUND: thermotherapy has been shown to be effective in the treatment of some fungal infections. Dermatophyte are well grown at 25degrees C rather than 37degrees C or high temperature. OBJECTIVE: An vitro test was done to assess the complemental effect and optimal conditions of local heating on the susceptability of t. rubrum to systemic antifungal agents. METHODS: Microdilution susceptability test to ketoconazole and itraconazole was done using 96 well microplate. Eight strains of T. rubrum were isolated from patients withtinea pedis and were cultured at 25degrees C, 37degrees C and 42degrees C for 1, 8 or 24 hours per day. MIC were checked at 4th, 7th, 9th day after inoculution. RESULTS: The growth without antifungal agents at 37degrees C and 42degrees C were decreased by 805 and 50% of the growth at 25degrees C respectively. Seven day after inoculation was the proper time to check the MIC. MIC50 of ketoconazole was the lowest at 42degrees C for 24hours per day in value of 0.006microgram/ml, and 0.09microgram/ml at 37degrees C for 24hours per day, 0.37microgram/mlat 42degrees C, for 8hours per day and 37degrees C for 8hours per day. MIC at 42degrees C for 1 hours er day, 37degrees C for 1 hyours and 25degrees C for 24hours per ady MIC were the same in value of 0.05microgram/ml. MIC50 of itraconazole was the lowest at 42degrees C for 24hours per day in value of 0.006microgram/ml, 0.01microgram/ml at 37degrees C for 24hours per day, 0.02microgram/ml at 37degrees C for 8hours per day. MIC at 42degrees C for 8hours per day, 42degrees C for 1hours per day, 37degrees C for 24hours per day MIC were the same in value of 0.05microgram/ml. CONCLUSION: Incubation at 37degrees C for 24 hours per day or 42degrees C for 24 hours per day increased the susceptability of T. rubrum to ketoconazole and itraconazole.
Antifungal Agents*
;
Arthrodermataceae*
;
Complement System Proteins
;
Heating
;
Hot Temperature
;
Humans
;
Hyperthermia, Induced
;
Itraconazole
;
Ketoconazole
6.Correlation of egg counts of Clonorchis sinensis by three methods of fecal examination.
Min Ho CHOI ; Tao GE ; Shang YUAN ; Sung Tae HONG
The Korean Journal of Parasitology 2005;43(3):115-117
The Kato-Katz (KK) method is a well-known method of fecal examination for helminthiases. Its diagnostic sensitivity was found very high for clonorchiasis. The present study evaluated the correlation of Clonorchis sinensis egg counts by the KK method with those by direct smear and formalin-ether (FE) technique. The egg counts obtained by the KK method (Y) were correlated with the counts by direct smear (X) with the equation of Y = 659.4 + 0.266X (r2= 0.738), but not with those by the FE method. The present study demonstrated that the KK method and direct smear were useful for both qualitative and quantitative diagnosis of clonorchiasis, especially in the field.
Animals
;
Cellophane
;
Clonorchiasis/*diagnosis/parasitology
;
Clonorchis sinensis/*isolation & purification
;
Comparative Study
;
Ether, Ethyl
;
Feces/parasitology
;
Formaldehyde
;
Humans
;
Parasite Egg Count/*methods
;
Sensitivity and Specificity
7.Histopathological Studies on Tumors of Testis in the Taegu Area.
Suk Jae HONG ; Tae Sook LEE ; Won Hee CHOI
Yeungnam University Journal of Medicine 1987;4(2):149-154
For evaluation on the histopathologic studies and age distribution of the testicular tumors in the Taegu area, the inguinal orchidectomized materials were collected at the Department of Pathology, College of Medicine, Yeungnam University, and the analyzed results were as follows: 1. In total of 11 cases of orchidectomized materials, germ cell tumors are 10 cases (90.9%). In germ cell tumors according to the histologic types, seminoma was 5 cases (45.5%), and embryonal carcinoma, 3 (27.2%). 2. The highest age incidence of the group is 20th and 30th, and the next, 50th and 10th.
Age Distribution
;
Carcinoma, Embryonal
;
Daegu*
;
Incidence
;
Neoplasms, Germ Cell and Embryonal
;
Pathology
;
Seminoma
;
Testicular Neoplasms
;
Testis*
8.A Clinical Observation on Spinal Stenosis
Chong Il YOO ; Ju Ho SONG ; Tae Hong CHOI
The Journal of the Korean Orthopaedic Association 1984;19(3):544-552
A clinical observation was made on 35 patients who were admitted to the Department of Orthopedic Sugery, Busan National University Hospital, 29 of whom had undergone operation from January 1979 to December 1983. The results obtained were as follows: 1. The peak incidence of age ranged from 51 to 60 years, which comprised 16 cases (45.7%) 2. The type of theDisease'were 15 cases with degenerative spinal stenosis, which comprised highest incidence, 11 cases with combined spinal stenosis, 6 cases with spondylolisthesis, 2 cases with idiopathic spinal stenosis and 1 case with iatrogenic spinal stenosis. 3. The duration of symptom before admisson ranged from 3 months to 20 years. Duration over 3 years comprised 54.3% of highest incidence. 4. The most common symptom on admission was pain in low back and leg, which comprised 31 cases (88.6%) and 4 cases had no specific neurologic deficit. 5. Myelogram was performed in 30 cases, C.T. scan in 7 cases and the most common myelographic finding was bilateral single level hour glass defect in 8 cases (26.7%). 6. Decompressive surgerys were done on 30 cases and post-operative results obtained were as follows: excellent in 11 cases (36.7%), good in 13 cases (43.3%), fair in 4 cases (13.3%) and poor in 2 cases (6.7%).
Busan
;
Glass
;
Humans
;
Incidence
;
Leg
;
Neurologic Manifestations
;
Orthopedics
;
Spinal Stenosis
;
Spondylolisthesis
9.A study of the factors influencing the compliance of hypertensivepatients to therapy.
Nam Hyeon CHOI ; Ki Hong KIM ; Jong Tae CHOI ; Ki Soon KIM
Journal of the Korean Academy of Family Medicine 1991;12(10):1-12
No abstract available.
Compliance*
10.Clinical and Histopathological Studies on Carcinoma of the Uterine Cervix in Taegu.
Joon Hyuk CHOI ; Won Hee CHOI ; Suk Jae HONG ; Tae Sook LEE
Yeungnam University Journal of Medicine 1988;5(2):121-128
Clinical and histopathological studies were made on 202 cases of malignancy of cervix, that were visited to the Department of Obstetrics and Gynecology, Yeungnam University Hospital, during 5 years from 1983 to 1987. The results were summarized as follows. 1. Malignancies of the uterine cervix were 10% of total female malignancies. 2. Among 202 cases, 195 cases (96.5%) were squamous cell carcinoma, in which 60 cases (30.0%) of carcinoma in situ, 9 cases (4%) of microinvasive, and 126 cases (62.5%) of invasive carcinoma were included. 3. The average age of the patients with squamous cell carcinoma was 49.4 years old; In case of carcinoma in situ, it was 43.8, microinvasive, 40.0, invasive 52.1 years old. 4. Clinical symptoms of the patient with squamous cell carcinoma in order of frequency were as follows; vaginal bleeding (47.5%), abnormal cytology (15.4%), and abnormal vaginal discharge (9.4%). 5. Duration of the chief complaints was most commonly less than 6 months (73.2%), and the average duration was 3.8 months. 6. The most common age of marriage was between 19 to 22 years old (46.5%). The average was 21.5 years old. 7. The gravity was 51.5% in 5-8 times, and average 6.2 times. The parity was 61.9% in 1-4 times, and average 3.9 times. 8. The subdivision of 126 cases of invasive carcinoma was made according to FIGO stage classification, stage I, 40 cases (31.8%), stage II, 54 cases(42.9%), stage III, 11 cases (8.7%), and stage IV, 8 cases (6.3%). 9. The histologic subtypes of invasive squamous cell carcinoma were distributed as follows; large cell keratinizing type, 25 cases (19.8%), large cell nonkeratinizing type, 101 cases (80.2%). 10. In the cytologic diagnosis, class I was 2 cases (1.9%), class II was 16 cases (15.1%), class III was 33 cases (31.1%), class IV was 31 cases (29.3%), class V was 24 cases (24.6%). 11. The frequency of lymph node metastasis was 7.5% in stage I, and 11.1% in stage II.
Carcinoma in Situ
;
Carcinoma, Squamous Cell
;
Cervix Uteri*
;
Classification
;
Daegu*
;
Diagnosis
;
Female
;
Gravitation
;
Gynecology
;
Humans
;
Lymph Nodes
;
Marriage
;
Neoplasm Metastasis
;
Obstetrics
;
Parity
;
Uterine Hemorrhage
;
Vaginal Discharge