The surgically treated 9 patients with anterior choroidal artery aneurysms were clinically analysed. The mean age of patients was fifty six and the size were between 3 mm and 12 mm. Anterior choroidal artery, although small, is important cerebral vessel because of its extensive strategic area of supply. We preserve anterior choroidal artery 8 out of 9 cases during clipping of aneurysm. Fortunately in the sacrificed case, no specific neurologic deficit was developed. So, we reviewed the anatomy & collateral circulation of this vessel.
Aneurysm* ; Arteries* ; Choroid* ; Collateral Circulation ; Humans ; Neurologic Manifestations

Spinal hemangioma is the uncommon, slowly growing benign tumor that arses from the blood vessels and was commonly located in the thoracic spine. The authors experienced 4 cases of spinal hemangioma from the thoracic spine that are diagnosed by simple spine X-ray, spine CT with myelography and confirmed by histological examination. We reviewed the literature concemed with spinal hemangioma.
Blood Vessels ; Hemangioma ; Myelography ; Spine

Sakai's method has been known as the simplest one for determination of erythrocyte pyrimidine 5'-nucleotidase (P5N) activity using high performance liquid chromatography(HPLC). However the drawback of the method is that it is difficult to wash the erythrocyte for isolation. To search for the simpler method, we compared Sakai's method with other methods using whole blood treated with heparin and concanavalin A or whole blood treated with EDTA-2K instead of washing the erythrocyte. The mean concentrations of lead in blood samples collected from 44 male and 16 female workers who are healthy without any exposure to lead in their workplace were 4.30 +/- 1.31 microgram /dl (mean +/-standard deviation), which were measured by frameless atomic absorption spectrophotometer. Erythrocyte P5N activities were measured by 3 methods; Sakai's method(Method I), using whole blood treated with heparin and concanavalin A (Method II), and using whole blood treated with EDTA-2K (Method III). The results were obtained as follows ; 1. The mean of erythrocyte P5N activity by Sakai's method(Method I) were 12.7 +/-2.47 amole uridine/hr/gm of Hb. 2. The mean of erythrocyte P5N activity by the method using heparinized whole blood treated with concanavalin A(Method II) were 13.1 +/-2.41 micromole uridine/hr/gm of Hb. 3. The difference of mean erythrocyte P5N activity between Method I and Method was not significant. 4. The erythrocyte P5N activity by the method using whole blood treated with EDTA-2K (Method III) was significantly different from Method I. We thought that omission of incubation period which was required on Method III using EDTA-2K caused the difference between Method I and Method III. 5. Simple linear regression equation for erythrocyte P5N activity between Method I (Y) and Method II(X) was significant: Y = -0.012 + 0.9724 X. These results suggest that the method using whole blood treated with heparin and concanavalin A is simpler to examine the erythrocyte P5N activity as a biological indicator of lead intoxication than Sakai's method.
5'-Nucleotidase* ; Absorption ; Concanavalin A ; Erythrocytes* ; Female ; Heparin ; Humans ; Linear Models ; Male

Sakai's method has been known as the simplest one for determination of erythrocyte pyrimidine 5'-nucleotidase (P5N) activity using high performance liquid chromatography(HPLC). However the drawback of the method is that it is difficult to wash the erythrocyte for isolation. To search for the simpler method, we compared Sakai's method with other methods using whole blood treated with heparin and concanavalin A or whole blood treated with EDTA-2K instead of washing the erythrocyte. The mean concentrations of lead in blood samples collected from 44 male and 16 female workers who are healthy without any exposure to lead in their workplace were 4.30 +/- 1.31 microgram /dl (mean +/-standard deviation), which were measured by frameless atomic absorption spectrophotometer. Erythrocyte P5N activities were measured by 3 methods; Sakai's method(Method I), using whole blood treated with heparin and concanavalin A (Method II), and using whole blood treated with EDTA-2K (Method III). The results were obtained as follows ; 1. The mean of erythrocyte P5N activity by Sakai's method(Method I) were 12.7 +/-2.47 amole uridine/hr/gm of Hb. 2. The mean of erythrocyte P5N activity by the method using heparinized whole blood treated with concanavalin A(Method II) were 13.1 +/-2.41 micromole uridine/hr/gm of Hb. 3. The difference of mean erythrocyte P5N activity between Method I and Method was not significant. 4. The erythrocyte P5N activity by the method using whole blood treated with EDTA-2K (Method III) was significantly different from Method I. We thought that omission of incubation period which was required on Method III using EDTA-2K caused the difference between Method I and Method III. 5. Simple linear regression equation for erythrocyte P5N activity between Method I (Y) and Method II(X) was significant: Y = -0.012 + 0.9724 X. These results suggest that the method using whole blood treated with heparin and concanavalin A is simpler to examine the erythrocyte P5N activity as a biological indicator of lead intoxication than Sakai's method.
5'-Nucleotidase* ; Absorption ; Concanavalin A ; Erythrocytes* ; Female ; Heparin ; Humans ; Linear Models ; Male

No abstract available.
Hemangioma, Cavernous* ; Urinary Bladder*

The brain is the highly organized organ which attributes to consciousness, memory and language. Approximately 85ml of oxygenated blood from the heart is delivered to the brain each minute. In human beings, a steady cerebral blood flow is maintained which cerebral structures are perfused roughly in proportion to their metabolic demands which are actively depend on function. Therefore, cerebral function is the most important physiologic regulator of cerebral blood flow. The measurement of cerebral blood flow is a very important toolin exploring the function of the human brain in healthand disease. An impairment of normal cerebral blood flow indicates clinical derangement of central neruous system. Besides the clinical sympatoms, cerebral blood flow investigation has become our main guideline for judging the timing of operation and prognosis of disease as well as evaluation of treatment. The determination of normal cerebral blood flow in Korean seemed to be enormously important for further study on this subject. For the purpose of establishing normal value of cerebral blood flow in Korean, the author have studied 93 healthy persons with 133Xe-inhalation method using Obrist's two compartmental analysis. Followings were the results. 1) Normal values of FI, ISI, and WIin children below the age of 9 were 113.5+/-36.9, 62.5+/-13.0 and 55.6+/-6.4 each. 2) Normal values of FI, ISI, and WI in the group above the age of 9 were 75.5+/-15.5, 44.6+/-5.7 and 43.1+/-3.95 each. 3) There was no significant difference between mean values of right and left side hemisphere. 4) There was significant decrease in r-CBF in the group above the age of 9, but the decrement by age since after the age of 9 was not significant statistically. 5) The difference of mean values among each lobe was not significant statistically.
Brain ; Child ; Consciousness ; Heart ; Humans ; Memory ; Oxygen ; Prognosis ; Reference Values

The number of persons with HIV infection in Korea have increased steadily, total number of HIV infection in Korea were 478 on August, 1995. To investigate the clinicoimmunologic manifestation of AIDS in Korea, we reviewed complete blood counts (CBC), CD4 counts, serum beta2-microglobulin level, opportunistic infections and cause of death for 19 AIDS patients who had been admitted or visited at Pusan national university hospital during the period of January, 1990 to August, 1995. 1) The predominant mode of HIV transmission was heterosexual contact(18), other modes of transmission were homosexual contact(1). Clues of diagnosis of HIV infection were routine occupational health examination(14), and opportunistic infection symptoms such as fever, coughing(4). 2) Mean CD4 cell counts(/mm3) were 53 +/- 72 totally, 22 +/- 27 for 8 dead patients at mean 2 month before, 91 +/- 87 for 7 living patients. There were not significant difference(p>0.05). 3) Serum beta2-microglobulin(MG;ug/ml) was measured at 12 patients, mean serum beta2-MG level was4.8 +/- 7.3 totally, 7.1 +/- 10.3 for 6 dead patients at mean 1.3 month before, 2.5 +/- 0.4 for 6 living patients. There were not significant(p>0.05). 4) At CBC examination, WBC(/mm3) was 5,932 +/- 2,899 totally, 5,452 +/- 3,436 for 10 dead patients, 6,500 +/- 2,221 for 9 living patients(p>0.05). Hb(g/dl) was 11,4 +/- 2.8 totally, 9.4 +/- 1.8 for dead patients, 13.6 +/- 1.8 for living patients(p<0.05). Lymphocyte count(/mm) was 1,255 +/- 800 totally, 731 +/- 424 for dead patients, 1,838716 for living patients(p<0.05). ESR(mm/h) was 72 +/- 47 totally, 97 +/- 33 for dead patients, 47 +/- 47 for living patients(p<0.05). 5) Opportunistic infections had developed at 14 patients, candidiasis 7, pneumocystis carinii pneumonia 5, tuberculosis 3, cytomegalovirus infection 2, herpes zoster 3, toxoplasmosis 1, cryptococcal infection 2, bacterial pneumonia 5, and herpes simplex l. Malignant lymphoma had developed in 1 patient. 6) Mean survival interval from diagnosis of HIV infection to death was 32.8 +/- 19.1 months, and the most common cause of death was pneumocystis carinii pneumonia, and other causes of death were meningitis, bacterial pneumonia and AIDS-wasting syndrome. Based on these results, We concluded that CD4 counts, serum beta2-microglobulin level, Hb, total lymphocyte count and ESR in AIDS patients are specific laboratory markers of progression and prognosis of AIDS, the most common opportunistic infection was candidiasis, and the most common cause of death in AIDS patients was pneumocystis carinii pneumonia.
Biomarkers ; Blood Cell Count ; Busan ; Candidiasis ; Cause of Death ; CD4 Lymphocyte Count ; Cytomegalovirus Infections ; Diagnosis ; Fever ; Herpes Simplex ; Herpes Zoster ; Heterosexuality ; HIV ; HIV Infections ; Homosexuality ; Humans ; Korea ; Lymphocyte Count ; Lymphocytes ; Lymphoma ; Meningitis, Bacterial ; Occupational Health ; Opportunistic Infections* ; Pneumonia ; Pneumonia, Bacterial ; Pneumonia, Pneumocystis ; Prognosis ; Toxoplasmosis ; Tuberculosis