BACKGROUND: To evaluate usefulness of cerebrospinal aspartate aminotransferase(AST) as a biologic marker for differentiation of Alzheimer's disease(AD) and Vascular dementia(VD) METHODS: A consecutive series of patients who met either the criteria of the National Institute of Neurological Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association(NINCDSADRDA) for probable AD or National Institute of Neurological Disorders and Stroke and the Association Internationale pour la Recherche et l'Enseignement en Neurosciences(NINDS-AIREN) criteria for porbable VD were included in the study. Enzymatic determinations in cere brospinal fluid of aspartate aminotransferase in cerebrospinal fluid of aspartate aminotransferase and serologic analysis of apolipoprotein E were performed in 17 patients with AD and in 15 patients with VD. And we compared CSF AST of AD with that of VD. RESULTS: We found no difference of CSF AST concentration between patients with Alzheimer's disease and vascular dementia. Cerebrospinal AST activity also did not correlate with K-MMSE score, serum AST activity, Functional inde-pence measure(FIM) as a ADL(Activity of daily living), and presence of Apolipoprotein E4 allele in AD. Only serum AST of VD shows correlation with CSF AST. CONCLUSION: These findings suggest that cerebrospinal AST concentration is not useful maker for differentiation between AD and VD.
Alleles ; Alzheimer Disease* ; Apolipoprotein E4 ; Apolipoproteins ; Aspartate Aminotransferases* ; Aspartic Acid* ; Biomarkers ; Cerebrospinal Fluid* ; Dementia, Vascular* ; Humans ; National Institute of Neurological Disorders and Stroke

An epidemiological survey on cholera was made toward the 291 cases admitted in Pusan National University Hospital. The results were as follows. 1. The most predominant age groups among all cholera patients were form 30 to 39(21.3%). 2. 74.9% of all cases got under the educational background of primary school and 69.4% of all cases occurred at the low income group. 3. Daily average numbers of patient were 6.2 and maximum numbers were 15, August 19, 1970. 4. Among the food eaten prior to onset, drinking water was the most predominant with 16.2% and next, food and noodle groups were 14.8% and 10.3% respectively. 5. Regarding incubation period, it was found that "within 48 hours" was 83 5%. 6. Patients occurred mainly in Suh Ku area with 105(36.1%) of all closes. 7. Carrie rates among family members were 1.78%. 8. Carrier rates among residents of epidemic area were 0.l2%.
Busan* ; Cholera* ; Drinking Water ; Humans

Retrocaval ureter is a rare embryologic venous system anomaly of genitourinary tract and its essentially to the right side. We have reported diagnosed preoperatively in 41 years old male with complaints of intermittent right flank pain, with gross hematuria, urinary frequency, nocturia, tenesmus, and high fever. I.V.P. revealed delayed dye excretion on the right side with pyelocalyectasis and ureterectasis of upper ureter and stenotic portion beneath ureter was non visualization. R.G.P. revealed same as I.V.P. and right ureter was `sickle shape` course and its descent alonged over the right side of 4th and 5th lumbar vertebra column. On post operation 8th days, I.V.P. revealed slightly reduced of previous marked dilated right pelviocalyceal system with upper ureter and preoperative placed ureter was corrected to normal course.
Adult ; Fever ; Flank Pain ; Hematuria ; Humans ; Male ; Nocturia ; Retrocaval Ureter* ; Spine ; Ureter

Statistical observation was made on in-patients in the Department of Urology, Inje Medical College, Pusan, Korea, during the period from June 1, 1979 to Aug. 31, 1980. 1. Among 237 cases of in-patients, 177 cases were male and 60 cases were female with a ratio of 3:1. Most common diseases were ureter stone (20. 9%), renal stone (9.4%), hydrocele (7.8%) in order. 2. Of 237 in-patients, operation was done in 178 cases (75%). 3. Of 178 operation cases, ureterolithotomy (15. 7%) was most common operation and nephrectomy (12. 9%), hydrocelectomy (10. 7%) in order.
Busan ; Female ; Humans ; Korea ; Male ; Nephrectomy ; Ureter ; Urology

No abstract available.
Lipodystrophy, Congenital Generalized*

A clinical observation was made on 202 cases of urinary stones during the period from June, 1979 to Mar., 1982 on the Department of Urology of Paik Hospital, Inje Medical College in Busan. 1. The incidence of urinary stone was 30.6% of in-patients. 2. Age distribution was 4 and 77 years old showing most incidence in 20 to 49 years in about 76.2%. 3. Sexual distribution was 135 cases of male (66.8%l and 67 cases of females (33.2%). 4, The location of urinary stone was 78.21% in the ureter, 16.34% in kidney. 2.97% in bladder & 2.48% in urethra. 5. The most favored predilection of ureteral stone was lower ureter in 65.8% of all cases. 6. Highest incidence in size of urinary stone was below of 0.5 cm & 2.0 cm in diameter and the majority of stone number was single (90.1%). 7. Among renal stones. staghorn types were 11 cases. 8. Leukocytosis shown in 68 cases (33.6%). 9. Microscopic pyuria was shown in 82 cases/40.6%) and hematuria was present in 122 cases (60.4%) and positive culture was present in 35 cases (17.3%) of all cases of urinary stones and more than 100,000 colony/ml was only 6 cases. 10.Serum B.U.N. level was above 20.1 mg/100ml in 21 cases (10.4%) and creatinine. above 2.1 mg/100ml in 6 cases (2.97%l and Ca. & P. level were relatively almost normal range. 11 .Hydronephrotic changes shown in 134 cases (66.3%) and non-visualized kidney was 36 cases (17.8%) on the I.V.P. 12.Chief complain of upper urinary calculi were flank pain 92.6%. suprapubic discomfort in 30.7%, nausea & vomiting 26.7%, hematuria in 25.7% and frequency with tenesmus in 18.3% and lower urinary calculi were most common symptoms of vesical irritation signs. 13.Surgical correction in 101 cases (50%), expectant therapy in 65 cases (32.2%) and cystoscopic stone manipulation in 36 cases (17.3%) were performed.
Age Distribution ; Aged ; Busan ; Creatinine ; Female ; Flank Pain ; Hematuria ; Humans ; Incidence ; Kidney ; Leukocytosis ; Male ; Nausea ; Pyuria ; Reference Values ; Ureter ; Urethra ; Urinary Bladder ; Urinary Calculi* ; Urology ; Vomiting

A case of adenocarcinoma in the bladder is presented in a 24 years old man with complained of intermittent total gross hematuria. Preoperative diagnosis was established by cystoscopy, which showed a walnut sized circular pedunculated mass posterior to the air bubble on the bladder dome. A urachal sinus was absent. Partial cystectomy was performed. Biopsy showed adenocarcinoma with well differentiated glandular epithelium.
Adenocarcinoma* ; Biopsy ; Cystectomy ; Cystoscopy ; Diagnosis ; Epithelium ; Hematuria ; Humans ; Juglans ; Urinary Bladder ; Young Adult

Forty-three cases of cryptorchidism, admitted to the Inje Medical College Hospital from Jun. 1979 to Mar. 1982, have been clinically analysed and the results were as follows. 1. The age distribution was ranging from 2 years to 30 years and under 5 years of age group was mostcommonly affected (13 cases, 30%). 2. The location of cryptorchidism is most frequently in the inguinal type (37 cases, 86%). 3. The bilateral cryptorchidisms were observed in 10 cases (23%), of the unilateral 33 cases, right in 20 casesand left in 13 cases. 4. Associated diseases and complications were found in 41 cases (95%) and the most common diseases werehernia in 36 cases (83%). 5. Hormonal therapy was done on 5 cases but there were no response. 6. Orchiopexy was performed on 43 testes, orchiectomy on 8 cases and 2 cases were confirmed as monoorchism on exploration. 7. In the histopathologic findings of testicular biopsy in 8 cases, there were small size of seminiferous tubules,germ cell aplasia, basement membrane thickening and aspermatogenesis.
Age Distribution ; Basement Membrane ; Biopsy ; Cryptorchidism* ; Humans ; Male ; Orchiectomy ; Orchiopexy ; Testis

No abstract available.
Cesarean Section* ; Cicatrix* ; Endometriosis* ; Female ; Pregnancy

No abstract available.
Ultrasonography*