1.A Case of Female Infertility Treated with Unkei-to after Clomifene-induced Ovarian Hyperstimulation Syndrome.
Takashi SUZUKI ; Takenori HARADA
Kampo Medicine 1997;48(2):211-216
A 26-year-old woman visited our hospital complaining of infertility. Initially treatment was given based on clomiphene for induction of ovulation. However, she suffered from ovarian hyperstimulation syndrome (OHSS) due to the clomiphene, accompanied by abdominal pain. Unkei-to was decided on as the best mode of treatment since clomiphene could not be continued. The patient's basal body temperature (BBT) returned to its biphasic cycle. Three months later, natural pregnancy occurred that resulted in the birth of a healthy boy by normal delivery.
Unkei-to is frequently given for a variety of gynecological disorders, such as irregular menstruation, dysmenorrhea, discharge, climacteric disturbance, etc.
Although induction of ovulation is often a necessary and effective infertility therapy, multiple pregnancies and OHSS can be problematic. The present case suggests that Unkei-to may be effective for infertility involving clomiphene-induced OHSS
2.Indications and Evaluation of Coronary Artery Bypass Grafting with Myocardial Single Photon Emission Tomography Using 123I-BMIPP, a New Tracer of Myocardial Metabolism of Fatty Acid.
Shintaro Nemoto ; Masanori Harada ; Takashi Oshitomi ; Masahiro Endo ; Hitoshi Koyanagi
Japanese Journal of Cardiovascular Surgery 1996;25(2):113-119
To evaluate viability and severity of ischemically damaged myocardium, myocardial single emission tomography (SPECT) using 123I-BMIPP (BMIPP), a new tracer of myocardial metabolism of fatty acid, was performed before and after coronary artery bypass grafting (CABG). 201Tl myocardial SPECT (Tl) and left ventriculography (LVG) were also used. Thirty-three revascularized areas in eight patients were investigated. (1) Areas showing good redistribution on Tl and normal uptake on BMIPP indicated good viability and simple ischemic myocardium. Postoperative uptake of both tracers returned to normal levels. (2) Areas showing good redistribution on Tl and severely decreased uptake on BMIPP indicated jeopardized myocardium with severe ischemia. All such areas were seen in patients with unstable angina. Postoperative uptake of both tracers returned to normal levels. (3) Areas showing poor redistributionor severely decreased uptake on Tl and slight uptake on BMIPP indicating hibernating areas. Postoperative uptake became normal or better than preoperative uptake on Tl necrosis. However on BMIPP, the uptake was unchanged or recovered slightly. (4) Areas showing complete defect in Tl and BMIPP indicated necrosis and had no viability. Postoperatively the defect in both tracers were unchanged. Therefore, these areas required no revascularization. The ischemic state of myocardium could be assessed by evaluation of uptake patterns of BMIPP and Tl using myocardial SPECT. Therefore, using this new tracer of myocardial fatty acid metabolism “BMIPP”is useful for deciding culprit and viable lesions requiring coronary revascularization and evaluating therapeutical effects.
4.Improvement of Pulmonary Function by Spa Therapy in Patients with Emphysema, Evaluated by Residual Volume(RV) and Low Attenuation Area(LAA) of High-Resolution Computed Tomography(HRCT).
Fumihiro MITSUNOBU ; Takashi MIFUNE ; Yasuhiro HOSAKI ; Kozo ASHIDA ; Hirofumi TSUGENO ; Makoto OKAMOTO ; Seishi HARADA ; Yoshiro TANIZAKI ; Koji OCHI ; Hideo HARADA
The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine 1999;62(3):121-128
5.A Recent 5-Year Study on 511 Patients with Chronic Obstructive Pulmonary Disease(COPD) Admitted at Misasa Medical Branch for Spa Therapy.
Takashi MIFUNE ; Fumihiro MITSUNOBU ; Yasuhiro HOSAKI ; Kozo ASHIDA ; Hirofumi TSUGENO ; Makoto OKAMOTO ; Seishi HARADA ; Yoshiro TANIZAKI ; Koji OCHI ; Hideo HARADA
The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine 1999;62(3):147-153
6.Effects of Spa Therapy on Patients with Pulmonary Emphysema. Relationship to disease severity evaluated by low attenuation area of the lung on high resolution computed tomography.
Fumihiro MITSUNOBU ; Takashi MIFUNE ; Yasuhiro HOSAKI ; Kouzou ASHIDA ; Hirofumi TSUGENO ; Makoto OKAMOTO ; Seishi HARADA ; Yoshiro TANIZAKI ; Koji OCHI ; Hideo HARADA
The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine 1998;61(2):79-86
7.Comparison of the front crawl leg kick and arm stroke characteristics of male age-group and college swimmers.
TAKASHI HARADA ; KAORU KITAGAWA ; SHIGEHIRO TAKAHASHI ; TAKESHI MATSUI ; NOBUO MATSUI ; TOSHIHIRO ISHIKO
Japanese Journal of Physical Fitness and Sports Medicine 1996;45(1):83-90
The purpose of this study was to determine the physiological responses, stroke rate and stroke length of front crawl leg kick and arm stroke of age-group and college swimmers and to elucidate the characteristics of male age-group swimmers, which have not been highlighted adequately. The subjects were ten 11.8-to 12.4-year-old well-trained male elementary school swimmers (group E) and nine 20.1-to 21.1-year-old well-trained male college swimmers (group C) . All the subjects were categorized into similar swimming levels for their ages. All the experiments were performed in a swimming flume (AQUAGYM made by IHI) . The water velocities during leg kicking and arm stroking were 60 and 70%, respectively, of the maximal velocity at maximal oxygen uptake (Vmax) . The oxygen uptake (VO2), heart rate (HR), pulmonary ventilation (VE), tidal volume (TV), respiratory rate (RR) and blood lactate (BL) level of each group were significantly higher during leg kicking than arm stroking at both velocities. VO2, VE; and TV were significantly higher in group C than group E during leg kicking and arm stroking at both velocities, but HR, RR and BL did not differ significantly. The leg kick to arm stroke VO2 ratio at 70% Vmax was significantly higher in group E than group C. The stroke rate at the same velocity was significantly lower and the stroke length was significantly higher in group C than group E, but the kick rate and length did not differ significantly. VO2·SR-1 and VO2 KR-1 at both velocities were significantly higher in group C than group E. VO2 Wt-1 SR-1 at 70% Vmax was significantly higher in group C than group E, but VO2 Wt-1 KR-1 at both velocities was significantly lower in group C than group E. These results clarified the differences between group E and group C, which must be considered carefully when designing a training program for age-group swimmers.
8.Clinical Effects of Spa Therapy on Bronchial Asthma. 7. Relationship between spa effects and airway inflammation.
Yoshiro TANIZAKI ; Hikaru KITANI ; Morihiro OKAZAKI ; Takashi MIFUNE ; Fumihiro MITSUNOBU ; Koji OCHI ; Hideo HARADA ; Ikuro KIMURA
The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine 1993;56(2):79-86
10.Distant Effect of Spa Therapy on Bronchial Asthma in Relation to Cellular Composition of the Airways and Ventilatory Function.
Yoshiro TANIZAKI ; Hikaru KITANI ; Takashi MIFUNE ; Fumihiro MITSUNOBU ; Kazuhiro KAJIMOTO ; Koji OCHI ; Hideo HARADA ; Ikuro KIMURA
The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine 1994;57(3):199-208