No abstract available.
Synapses

It is essential to search medical information precisely and efficiently in every aspect of medical practices and research activities. The growth of the medical literature has been tremendous in recent years, as exemplified by the annual growth of 710,000 records in MEDLINE in 2009, thus increasing the complexities of literature searching. Yet database search environments are changing toward very user-friendly ways facilitated by various hypertext linking capabilities such as "LinkOuts" to full texts and "reference linkings" among articles using Digital Object Identifiers (DOIs). Once a direct search of a keyword is initiated, a searcher can continue searching endlessly and seamlessly by simply clicking various links provided in the records retrieved. Search behaviors of researchers are changing accordingly, avoiding any complex or advanced searches. The basics of database search methods are described in this paper. A brief overview of major medical databases is given by database type to illustrate the differences in the information retrievable from such databases: MEDLINE/PubMed and KoreaMed are abstract databases; SCI/Web of Science, SCOPUS and KoMCI are citation indexes; and PubMed Central and Synapse are full text databases. Some of the advanced search features of each database are also noted: searches using MeSH terms in PubMed and KoreaMed; differences in the "related documents" algorithms of PubMed and SCI; citation analysis using "analyze results" in Web of Science and SCOPUS; and citation tracking in Synapse and PubMed. The Journal of the Korean Medical Association (JKMA) records are used for the illustration of such features.
Hypermedia ; Synapses ; Track and Field

No abstract available.
Animals ; Neostriatum* ; Rats* ; Synapses*

The Korean Journal of Urology began to be published exclusively in English in 2010 and is indexed in PubMed Central/PubMed. This study analyzed a variety of citation indicators of the Korean Journal of Urology before and after 2010 to clarify the present position of the journal among the urology category journals. The impact factor, SCImago Journal Rank (SJR), impact index, Z-impact factor (ZIF, impact factor excluding self-citation), and Hirsch Index (H-index) were referenced or calculated from Web of Science, Scopus, SCImago Journal & Country Ranking, Korean Medical Citation Index (KoMCI), KoreaMed Synapse, and Google Scholar. Both the impact factor and the total citations rose rapidly beginning in 2011. The 2012 impact factor corresponded to the upper 84.9% in the nephrology-urology category, whereas the 2011 SJR was in the upper 58.5%. The ZIF in KoMCI was one fifth of the impact factor because there are only two other urology journals in KoMCI. Up to 2009, more than half of the citations in the Web of Science were from Korean researchers, but from 2010 to 2012, more than 85% of the citations were from international researchers. The H-indexes from Web of Science, Scopus, KoMCI, KoreaMed Synapse, and Google Scholar were 8, 10, 12, 9, and 18, respectively. The strategy of the language change in 2010 was successful from the perspective of citation indicators. The values of the citation indicators will continue to increase rapidly and consistently as the research achievement of authors of the Korean Journal of Urology increases.
Achievement ; Bibliometrics ; Korea ; Synapses ; Urology

Publication lag is a determinant to journal efficiency that was not yet studied concerning Korean medical journals. To measure publication lag, we investigated the publication timestamps of 4,762 articles published by 10 Korean medical journals indexed in Scopus database, randomly selected from the KoreaMed Synapse since 2013. The total publication lag was 246.5 (Q1, Q3; 178.0, 347.0) days. The overall acceptance lag was 102.0 (65.0, 149.0) days. The overall lead lag was 123.0 (63.0, 236.0) days. The year of publication did not significantly affect the acceptance lag (P = 0.640), supposedly shortening it by about 1.4 (97.5% confidence interval [CI], −5.2 to 8.0) days/year, while the date affected the lead lag (P = 0.028), shortening it by about 12.9 (1.3 to 24.5) days/year. The Korean medical journals have reduced the total publication delay entirely by means of reducing the lead lag, not by reducing the acceptance lag.
Bibliometrics ; Peer Review ; Publications* ; Synapses

No abstract available.
Animals ; Brain* ; Neurons* ; Rats* ; Synapses*

No abstract available.
Animals ; Hippocampus* ; Rats* ; Serotonin* ; Synapses*

No abstract available.
Animals ; Olfactory Bulb* ; Olfactory Mucosa* ; Rats* ; Synapses*

In order to understand the pathogenesis and progression of some synaptic loss related neuropsychiatric diseases. We attempted to develop a computer model in this study. We made a simple autoassociative memory network remembering numbers, transformed it into a disease model by pruning synapses, and measured its memory performance as a function of synaptic deletion. Decline in performance was measured as amount of synaptic loss increases and its mode of declines is sudden or gradual according to the mode of synaptic pruning. The developed computer model demonstrated how synaptic loss could cause memory impairment through a series of computer simulations, and suggested a new way of research in neuropsychiatry.
Computer Simulation* ; Dementia ; Memory ; Neuropsychiatry ; Schizophrenia ; Synapses

Female ; Humans ; Male ; Neuronal Plasticity ; Synapses ; Vasopressins