BACKGROUND: Classical surgical treatment of axillary osmidrosis and hyperhidrosis results in many complications such as scarring, hematoma and necrosis, therefore, gentle skin flap cares is needed. OBJECTIVE: In order to lessen the complications and to obtain an improved clinical outcome, a new easy-learn, surgical excision method of treating subcutaneous tissue is required. METHOD: On 16 patients, We carried out a type-1 surgical method to treat axillary osmidrosis and hyperhidrosis. This invoved major removal of the subcutaneous tissue by scissor excision, and partial removal by the subwtaneous shaver method, to minimise trauma. We then analyzed the clinical efficiency, complications, patient satisfaction, and pathologic specimens according to clinical severity. RESULTS: All 16 patients showed an improved odor or sweating pattern, and a good or very good level of satisfaction. One patient also showed that hematoma was improved with proper post- operative care. Hyperactivity of the apocrine glands in osmidrosis and eccrine gland in hyperhidrosis was seen, and various morphologic features of apoeccrine glands were found in both osmidrosis and hyperhidrosis. We observed that apocrine and eccrine glands were completely excised by following the biopsy of 2 patients. CONCLUSION: Our present method of minimal skin incision and major removal of subcutaneous fat with manual scissor excision, in combination with partial excision with the subcutaneous shaver method, showed a good clinical outcome and few complications.
Apocrine Glands ; Biopsy ; Cicatrix ; Eccrine Glands ; Hematoma ; Humans ; Hyperhidrosis* ; Necrosis ; Odors ; Patient Satisfaction ; Skin ; Subcutaneous Fat ; Subcutaneous Tissue* ; Sweat ; Sweating

Eccrine porocarcinoma is a very rare, locally-aggressive, potentially fatal, malignant cutaneous neoplasm that arises from the intraepithelial ductal portion of the eccrine sweat gland. Eccrine porocarcinoma may develop either spontaneously or from a longstanding benign eccrine poroma. Herein, we describe two cases of eccrine porocarcinoma and review the related literature.
Eccrine Porocarcinoma* ; Poroma ; Sweat Glands

The histogenesis and differentiation of sweat gland tumors are controversial. Twenty-two cases of sweat gland tumors were stained by immunoperoxidase technique (ABC method) for the presence of S-100 protein, CEA, and two kinds of keratin. Four syringomas, 4 eccrine poromas, 2 eccrine porocarcinomas, 2 eccrine spiradenomas, 1 papillary eccrine adenoma, 3 clear cell hidradenomas, 3 mixed tumors of skin, 2 papillary syringocystadenomas, and 1 cylindroma were included. All samples were formalin-fixed and paraffin-erribedded. Two monoclonal cytokeratin ant.ibodies, MA-902 (specific for cytokeratin No. 8) and MA-903 (specific for cytokeratins No.1,5,10,11) were used. In normal eccrine and apocrine glands, MA-902 stains cells of the intradermal duct and secretory portion. While MA-903 stains cells of the intraepidermal and intradermal duct and myoepithelial cells of eccine and apocrine glands, S-100 protein is found in the secretory cells of the intradermalduct and secretory portion, while CEA stains the secretory and ductal cells of eccrine and apocrine glands. All sweat gland tumors we studied stained by 4 antibodies in variable positive rates, Based on these findings, we discuss the histogenesis of various sweat gland tumors.
Acrospiroma ; Adenoma ; Antibodies ; Apocrine Glands ; Carcinoma, Adenoid Cystic ; Coloring Agents ; Eccrine Porocarcinoma ; Immunoenzyme Techniques ; Keratins ; Poroma ; S100 Proteins ; Skin ; Sweat Glands* ; Sweat* ; Syringoma

Apocrine sweat gland carcinoma is a very unusual malignant skin adnexal tumor and mostly occurs in areas where apocrine elands are abundant namely. axilla. upper arm. scalp. eyelid. vulva and external auditory meatus. The scrotal location is not yet reported. We report a case of apocrine sweat gland carcinoma of scrotum in a man aged 85, which was managed by local excision. The histologic finding is that of poorly differentiated adenocarcinoma. Evidence of decapitation secretion typical or apocrine glands. is present in some areas.
Adenocarcinoma ; Apocrine Glands ; Arm ; Axilla ; Decapitation ; Eyelids ; Scalp ; Scrotum* ; Skin ; Sweat Glands* ; Sweat* ; Vulva

Proliferating trichilemmal cyst(PTC) is a rare benign neoplasm that is thought to be derived from the outer root sheath of anagen hair follicles differentiating toward the infundibular and matrical segments, sebaceous glands, apocrine glands, or acrosyringium. Clinically, it presents as a solitary elevated, lobulated mass on the scalp of elderly women. Histologically, it shows well demarcated multiple lobules of squamous epithelium. The center of the lobule undergoes abrupt keratinization without formation of keratohyalin and foci of calcification are often present in the areas of amorphous keratin. PTC can be associated with sebaceous nevus of Jadassohn, ectopic apocrine sweat glands, spindle cell carcinoma, etc. We report an unusual case of proliferating trichilemmal cyst with trichoepitheliomatous change in a young woman.
Aged ; Apocrine Glands ; Epithelium ; Female ; Hair Follicle ; Humans ; Nevus, Sebaceous of Jadassohn ; Scalp ; Sebaceous Glands ; Sweat Glands

Chromhidriosis or the production of colored sweat is a rare clinical finding. Several dyes, when injected intravenously, have been shown to be secreted in eccrine gland, but in most cases the sweat is colored in skin surface, resulting from the contamination by dyes, pigment from microorganisms, or other chemicals. We report a case of eccrine chromhidriosis which revealed blue-green spots on palms, soles, buttocks, and back.
Buttocks ; Coloring Agents ; Eccrine Glands ; Skin ; Sweat

Sweat glands are widely distributed in human skin, among which eccrine sweat glands play major roles in heat dissipation and sweat secretion. Sweat secretion is mainly regulated by nervous system and includes two processes of secretion of secretory coil and reabsorption of sweat duct, involving various ion channels and proteins such as calcium ion channel, potassium ion channel, sodium-potassium-chloride co-transporter 1, Best2 protein, aquaporin 5, cystic fibrosis transmembrane conductance regulator, and epithelial sodium ion channel. This paper reviews the nerve conduction system and various ion channels involved in sweat secretion of exocrine sweat glands in order to provide a theoretical basis for the study of regeneration, repair, and transformation of stem cells.
Eccrine Glands/metabolism* ; Humans ; Sweat/metabolism*

Tumors occurring in the external auditory canal (EAC) are rare. In particular, tubular adenoma (TA) is an extremely rare sweat gland neoplasm occurring in the EAC and is generally considered as benign. Up to now, less than one hundred cases of TA have been reported in the English literature. In fact, a comprehensive review of literature shows that TA in the EAC has seldom been reported. Herein, we report a case of a 35-year-old man with TA that occured in the EAC, together with characteristic histopathological findings.
Adenoma ; Aminocaproic Acids ; Apocrine Glands ; Ear Canal ; Sweat Gland Neoplasms

Eccrine angiomatous hamartoma (EAH) is a benign, uncommon cutaneous lesion, often localized to the distal extremities of children. It usually presents as a solitary, asymptomatic lesion that appears as a nodule or plaque, but sometimes it can occur as multiple lesions. Varying degrees of hyperhidrosis and pain have been reported. The histological feature is characterized by a proliferation of eccrine sweat glands and angiomatous channels. Occasionally, other elements are involved, such as mucin-secreting cells, adipose tissue, bony structures, apocrine glands or hair structures. We describe a case of eccrine angiomatous hamartoma with unusual lipomatous involvement.
Adipose Tissue ; Apocrine Glands ; Child ; Extremities ; Hair ; Hamartoma ; Humans ; Hyperhidrosis ; Sweat Glands

Malignant eccrine poroma is a rare skin appendageal tumor arising from the intraepidermal ductal portion of the eccrine sweat gland. It may develop either spontaneously or from a long-standing eccrine poroma. It usually affects the aged and is located most commonly on lower extremities. We report a case of malignant eccrine poroma occurring on the suprapubic area of a 75-year-old Korean man. He underwent wide excision and flap coverage.
Aged ; Eccrine Porocarcinoma ; Humans ; Lower Extremity ; Poroma ; Skin ; Sweat Glands