As a special media of politics and culture spreading,internet has a unique influence on politics socialization due to its characteristics of openness,reciprocity,and anonymity.Combined with the features of medical students,this paper analyzes the positive and negative impacts of internet media on the politics socialization of medical students,and comes up with feasible countermeasures for promoting the politics socialization of medical students in current information era.

Objective This article made an exploration on the feasibility of combined applica-tion of TBL with LBL in immunology experiment teaching, and analyzed teaching effectiveness of such combined model in order to find a new way of teaching reformation. Methods 2012 grade biophar-maceutical technology students were chosen in this research, one class as the experimental group(n=42), the other one as control group(n=42). In the experimental group, students were taught on a TBL+LBL combination model, while in the control group, students were taught only on LBL model. After the course was finished, effects of teaching were evaluated by questionnaire survey and compre-hensive ability evaluation. SPSS 18.0 software was used to do statistical analysis. Quantitative data and qualitative data were analyzed by t test and chi-square test respectively. P<0.05 means that difference is statistically significant. Results Above 90.0% of students in experiment group approved that TBL+LBL can improve the interest in learning , can enhance sense of teamwork , can help acquiring of knowledge and improving of individual comprehensive ability. Average score of comprehensive ability evaluation and percentage of students achieving good score in experimental group were higher than those in control group, the differences were statistically significant(t=2.020, P=0.049; χ2=6.372, P=0.012). Conclusion The TBL+LBL combination model can improve immunology experiment teach-ing quality, and is worth publicizing.

Objective To evaluate the quality of cryoprecipitates prepared from fresh frozen plasma via deepfreeze method and siphonage method thawing at 4℃ water bath,and to select a proper preparation method for cryoprecipitates.Methods Sixty samples of cryoprecipitate prepared by deepfreeze method,and 60 samples of cryoprecipitate prepared by siphonage method were selected randomly.Factor FⅧ,fibrinogen(Fg) in cryoprecipitates were measured by coagulometer,and the qualification rates were calculated.Results The concentration of FⅧ(IU/pack) in the cryoprecipitates prepared via deepfreeze method and siphonage method were(70.30?23.68),and(161.62?39.45),respectively;the qualification rate of FⅧ prepared via the two methods were 43.33%(26/60),and 93.33%(56/60),respectively(P0.05).Conclusion Siphonage method,with a higher qualification rate of FⅧ,is simple and fast,which deserves a popular application.

Objective To study the MR imaging features of intracranial epidermal cyst.Methods 18 cases(include 7 male,11 female) epidermal cyst pathology confirmed were analysed.Results The epidermal cyst usually exhibited heterogeneously low signal intensity on T 1WI(88.9%),and only 2 patients showed high signal intensity on T 1WI(11.1%).After contrast medium enhancement 16 cases had no obvious enhancement,only 2 patients had rim light enhancement .Conclusion Typical epidermal cyst commonly show heterogenously low signal intensity on T 1WI. A typcal epidermal cyst has high signal intensity on T 1WI.Differential diagnosis shoud be consider on these kind of epidermal cyst.

ObjectiveDiscussion early period diagnosis uterine scar pregnancy effective method.Methods According to clinical medical history,HCG test,Type-B ultrasonic ( MR if Necessary) diagnosis.Under type-B ultrasonic monitoring clear uterine after interventional embolization of uterine artery drug infusion.Results41 cases (89.13％ ) according to clinical mdical history,HCG test,Type-B ultrasonic diagnosis.5 cases( 10.87％ ) diagnosed with nuclear magnetic resonance(MR),diagnosis rate 100％.46 cases disposable thorough clear uterine after interventional? embolization of uterine artery drug infusion,cure rate 100％.ConclusionAccording of clinical medical history,HCG test,Type-B ultrasonic was the best method of diagnosis uterine scar pregnancy in early period.Using interventional embolization of uterine artery drug infusion and then clear it,it was Safe reliable method.

Objective To study the efficacy and safety of pulmonary surfactant used in hyaline membrane disease(HMD)of newborn treatment.Methods 67 cases of HMD children were treated.And pulmonary surfactant was used by intratracheal instillation.Clinical manifestation,blood gas analysis,X-ray chest film and complication before and after treatment were observed and recorded.Results 65 cases of children were recovered and discharged(97.01％),while 2 cases were dead.The PO2 increased significantly after the surfactant was given(P＜0.05),while the PCO2 decreased significantly(P＜0.05),and situation of skin cyanosis was relieved.X-ray chest films in 24 hours showed that 62 cases were improved(92.54％),while 4 cases were not obvious(5.97％),and there was hemorrhage image in the last 1 caes(1.49％).There were 5 cases of complication,involving 3 cases of pneumonia,1 case of intracranial hemorrhage and 1 case of pulmonary hemorrhage.Conclusion Clinical symptoms could be impurved rapidly,pulmonary oxygenation could be ameliorated,the need of mechanical ventilation could be lower and the rate of incidence of complication and death could be reduced effectively by using pulmonary surfactant early.

Objective:To investigate the resting energy expenditure of children with mechanical ventilation and analyze their association with anthropometric indicators (height, weight, and body mass index) and serum protein markers (pre-albumin, albumin, transferrin, and retinol).Methods:An observational study was held in Pediatric Intensive Care Unit(PICU) of Beijing Children′s Hospital, Capital Medical University, from August 2015 to April 2016.Critically ill children with mechanical ventilation were enrolled in this study.Inclusion criteria were as follows: (1)pediatric critical illness score<90 scores or meet the United States PICU admission criteria; (2)age>29 days, <18 years old; (3)mechanical ventilation>24 hours; (4) tidal volume >60 mL.Resting energy expenditure was determined by US Med Graphic Company CCM/D energy metabolism test system.German Famed Zywier intensive care bed with weight scale weighing, uniform measuring bed or meter measuring height, automatic biochemical analyzer and radioimmunoassay was adopted for the determination of albumin, pre-albumin, transferrin, retinol binding protein.SPSS 20.0 software was applied for carrying out Pearson line analysis correlation. Results:A total of 68 children were included in the study, including 36 males and 32 females, body weight (22.34±14.89) kg, height (122.23±14.89) cm, resting energy consumption (784.63±278.25) kcal(1 kcal=4.185 kJ), and resting energy consumption per kilogram of body weight (48.80±31.26) kcal.In anthropometric indicators, resting energy expenditure was significantly positively correlated with height, body weight ( r=0.764, 0.734, all P<0.05), a low positive correlation with body mass index( r=0.396, P<0.05). In serum proteomics, resting energy expenditure was negatively correlated with pre-albumin, transferrin ( r=-0.318, -0.282, all P<0.05), and a moderate negative correlation with retinol protein ( r=-0.505, P<0.05), while without correlation with albumin ( r=-0.075, P>0.05). Conclusions:The height, weight and serum proteomics of children with mechanical ventilation may affect resting energy expenditure.

Objective　To find out the morbidity and main pathogens of ventilator-associated pneumonia(VAP) in PICU.Methods　44 VAP cases were reviewed.Results　44 VAP cases were diagnosed and analyzed from 1998, 2 to 2001,1,the morbidity of VAP was 69.8%.The predominant pathogen was Pseudomonas aeruginosa.Conclusion　It has reference value in consideri ng the possible pathogens of pneumonia.

Objective To evaluate the images of MRCP acquired by adjusting 0.3 Tesla MR unit heavy T 2-weighted scanning parameters and altering scanning angle and diagnostic correctivity to biliary obstructive disease.Methods Routine MR T 1WI,T 2WI scanning were performed axial in 50 cases of patients with biliary obstruction.All of them were divided into two groups,20 cases of them were scanned coronal with FSE T 2-weighted fixed parameters,30 cases of them were scanned with altering scanning angle,increasing scanning slices,decreasing distance of two near slices,reducing signal collection times(NSA),shortening scanning time.Results The acquired images through adjusting FSE T 2-weighted scanning parameters were visualized clearly.The boundary of cholangiopancreatie ducts were showed clearly.The display rate of biliary and pancreatie ducts was elevaled from 20% to 83.3%.The accuracy of it for evaluating the causes of obstruction was increased from 88.9% to 93.3%.The accuracy of it in the detection of the location of bile duct obstruction was 100%.Conclusion Through adjusting scanning purameters low field MRCP is very helpful in improved images quality and reflecting veliable signs of biliary and pancreatie duct obstruction disease combined with MRI T 1-weighted T 2-weighted message.This method can increased the diagnostic accuracy of the causes of obseruction and supply the reliable ground for clinical treatment.

Objective To investigate the expression of nm23-H1 in human benign and malignant colorectal lesions and the relationship between invasion,metastasis in colorectal carcinoma.Methods The expression of nm23-H1 were determined by ABC immunohistochemical technique in 80 cases human colorectal carcinoma,and compared with that in adenoma and normal mucus.Result Positivity expression rates of nm23-H1 were 66.7% in colorectal carcinoma.No significant difference of the expression of nm23-H1 in normal mucus,adenoma and cancerous tissue (P>0.05).The positive rates of nm23-H1 expression in different pathological grading,lymph node metastasis and post-operative survival (3 years) were showed significant difference (P<0.05).Conclusions It is suggested that the deletion of nm23-H1 low expression might play an important role in the carcinogenesis,development,metastasis and prognostic value of human colorectal carcinoma.