ObjectiveTo give health guidance and intervention to Alzheimer's patients and observe its impact on their quality of life. MethodsBasic care, psychological care and safety of care measures were given to 45 Alzheimer's patients in our hospital from March 2007 to September 2008, self-care ability and cognitive ability were observed. ResultsThe Alzheimer's patients were alleviated in the following symptoms such as accidental aspiration, wrong intake, falls, self- injury, straying away, self- care ability, cognitive ability and social skills. ConclusionsStrengthening of diet and daily life care, attention to psy-chological and safety care in patients with Alzheimer's disease can improve their quality of life, which is worthy of hospital, community and family promotion.